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AAPM 2025 - 67th Annual Meeting & Exhibition of the American Association of Physicists in Medicine

AI-Powered Mammography Screening Boosts Cancer Detection in Single-Reader Settings

By MedImaging International staff writers
Posted on 12 Mar 2025

Image: The INSIGHT MMG AI-powered mammography analysis solution (Photo courtesy of Lunit)

A new study has revealed that an artificial intelligence (AI)-powered solution significantly improves cancer detection in single-reader mammography settings without increasing recall rates, offering a transformative tool for countries that rely on single-reader mammography screenings.

This pioneering prospective study validated the real-world effectiveness of AI-driven mammography screening within South Korea's national breast cancer screening program. Conducted as the first large-scale, multicenter prospective study in a single-reading setting globally, the research highlights the significant improvements AI-assisted mammography interpretation brings to breast cancer detection, all while maintaining steady recall rates. Led by Soonchunhyang University Seoul Hospital (Seoul, South Korea), in collaboration with breast and general radiologists from six top academic hospitals in South Korea, the study analyzed 24,543 women aged 40 and older who underwent routine biennial mammography (2D full-field digital mammogram) between February 2021 and December 2022 as part of Korea's national screening initiative.

The study compared the performance of breast radiologists interpreting screening mammograms with and without Lunit’s (Seoul, South Korea) AI-based computer-aided detection, Lunit INSIGHT MMG. Results indicated that AI-assisted radiologists detected 13.8% more screen-detected breast cancers compared to those using traditional methods alone. The cancer detection rate (CDR) increased from 5.01 (per 1,000) to 5.70 with AI assistance, while recall rates (RRs) remained statistically unchanged, ensuring enhanced clinical effectiveness while avoiding unnecessary additional recalls. Additionally, AI assistance significantly improved the detection of smaller tumors and node-negative cancers, crucial indicators of early-stage detection. The study also assessed the impact of Lunit INSIGHT MMG on general radiologists without breast imaging expertise through a simulated retrospective study. The findings, published in Nature Communications, showed a 26.4% increase in CDRs for general radiologists, improving from 3.87 to 4.89 per 1,000, highlighting AI’s potential to assist radiologists with varying expertise.

This study builds upon Lunit INSIGHT MMG's established ability to enhance breast cancer detection. The findings are poised to influence breast cancer screening practices globally, especially in countries where single-reading mammography is standard. By demonstrating AI’s ability to improve radiologist accuracy without raising recall rates, the study provides essential data supporting AI’s role in optimizing cancer detection while alleviating radiologists’ workload. This is particularly pertinent as many countries face a shortage of specialized breast imaging professionals, making AI a crucial tool for improving efficiency and maintaining high diagnostic standards. With growing evidence supporting AI's effectiveness in breast cancer screening, Lunit is advancing its global adoption. Lunit INSIGHT MMG has already been implemented in national screening programs in Australia, Sweden, Iceland, Singapore, Saudi Arabia, and Qatar, helping healthcare systems increase efficiency and improve diagnostic accuracy.

"This latest prospective study in South Korea further solidifies Lunit INSIGHT MMG's potential as an indispensable tool in breast cancer screening. Whether in a single-reader or double-reader setting, AI can serve as a powerful force multiplier, assisting radiologists in detecting cancer earlier and more accurately," said Brandon Suh, CEO of Lunit. "As AI adoption accelerates, we remain committed to driving innovation and making AI-powered cancer screening the new standard of care. By working closely with healthcare providers worldwide, we aim to ensure that AI benefits as many patients as possible."

Related Links:
Lunit
Soonchunhyang University Seoul Hospital

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80 (34.809112548828): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

89 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

90 (65.088272094727): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804313 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804313 AND published='1' LIMIT 1

91 (45.061111450195): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804313 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804313 AND published='1' LIMIT 1

92 (57.93571472168): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294804313 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

93 (211.95411682129): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804313 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804313 AND published='1' LIMIT 1

94 (108.00361633301): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804313 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804313 AND published='1' LIMIT 1

95 (392.19856262207): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294804313 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

96 (595.0927734375): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

97 (410.07995605469): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

98 (73.19450378418): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804313 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804313 AND published='1' LIMIT 1

99 (45.061111450195): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804313 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804313 AND published='1' LIMIT 1

100 (48.87580871582): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804313 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804313 AND published='1' LIMIT 1

101 (66.995620727539): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804313 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804313 AND published='1' LIMIT 1

102 (42.200088500977): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804313 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804313 AND published='1' LIMIT 1

103 (252.96211242676): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804313 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804313 AND published='1' LIMIT 1

104 (143.05114746094): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804313 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804313 AND published='1' LIMIT 1

105 (95.844268798828): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804313 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804313 AND published='1' LIMIT 1

106 (338.07754516602): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

107 (!!!!! 19762.992858887): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

108 (479.93659973145): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294804313 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294804313 AND type='deeppockets_item' AND published='1' LIMIT 1

109 (!!!!! 7562.8757476807): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

110 (75.101852416992): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

111 (294.92378234863): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

112 (91.075897216797): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

113 (215.05355834961): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

114 (48.160552978516): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

115 (258.9225769043): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

116 (43.153762817383): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

117 (185.96649169922): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

118 (36.954879760742): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

119 (400.06637573242): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804313 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

120 (185.01281738281): SELECT name FROM jos_deeppockets WHERE id=211

121 (51.975250244141): SELECT name FROM jos_deeppockets WHERE id=211

122 (823.02093505859): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

123 (809.90791320801): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

124 (151.8726348877): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804313 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804313 AND published='1' LIMIT 1

125 (83.92333984375): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804313 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804313 AND published='1' LIMIT 1

126 (!!!!! 5568.0274963379): TRUNCATE TABLE jos_trademed_module

127 (111.81831359863): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294804313 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

128 (426.05400085449): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804313 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

129 (51.975250244141): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804313 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

130 (52.928924560547): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804313 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804313 AND published='1' LIMIT 1

131 (41.007995605469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804313 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804313 AND published='1' LIMIT 1

132 (!!!!! 1146.0781097412): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

133 (50.067901611328): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804313 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804313 AND published='1' LIMIT 1

134 (41.961669921875): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804313 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804313 AND published='1' LIMIT 1

135 (31.948089599609): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294804313 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294804313 AND type='deeppockets_item' AND published='1' LIMIT 1

136 (29.087066650391): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

137 (26.941299438477): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

138 (30.994415283203): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

139 (725.98457336426): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804313 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804313 AND published='1' LIMIT 1

140 (51.975250244141): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804313 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804313 AND published='1' LIMIT 1

141 (103.95050048828): select jos_twitters.link from jos_twitters where cat=10

142 (28.133392333984): select jos_facebook.link from jos_facebook where cat=10

143 (28.133392333984): select jos_google_plus.link from jos_google_plus where cat=10

144 (26.941299438477): select jos_linkedin.link from jos_linkedin where cat=10

145 (412.2257232666): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

146 (!!!!! 1214.9810791016): insert into jos_banners_delta values (14615,'2025-06-21 01:30:27','216.73.216.120','view'),(14202,'2025-06-21 01:30:27','216.73.216.120','view'),(14203,'2025-06-21 01:30:27','216.73.216.120','view')

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