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27 Jul 2025 - 30 Jul 2025

AAPM 2025 - 67th Annual Meeting & Exhibition of the American Association of Physicists in Medicine

Ultra-Powerful MRI Scans Enable Life-Changing Surgery in Treatment-Resistant Epileptic Patients

By MedImaging International staff writers
Posted on 24 Mar 2025

Image: Comparison showing 3T and 7T scans for the same participant (Photo courtesy of P Simon Jones/University of Cambridge)

Approximately 360,000 individuals in the UK suffer from focal epilepsy, a condition in which seizures spread from one part of the brain. Around a third of these patients experience persistent seizures despite taking medication, and surgery remains the only treatment capable of curing their condition. Epileptic seizures are the sixth leading cause of hospital admissions. For surgeons to perform the necessary operation, they must accurately identify the brain lesions (damaged tissue) responsible for triggering seizures. By visualizing these lesions on MRI scans, surgeons can significantly increase the chances of the patient being seizure-free after surgery. Ultra-high-field 7T MRI scanners provide much higher resolution scans than the NHS’s standard 3T MRI scanners, enabling better detection of these lesions in patients with drug-resistant epilepsy. However, most NHS hospitals use even lower field strength, such as 1.5T scanners. Despite the advantages of 7T MRI, these scans are prone to signal dropouts, particularly in the temporal lobes, which is the area most commonly affected by epilepsy. Now, a new study published in Epilepsia has presented a technique to address this issue.

The research team from the University of Cambridge’s Wolfson Brain Imaging Centre (Cambridge, UK), in collaboration with colleagues from Université Paris-Saclay (Paris, France), applied a technique called ‘parallel transmit,’ which uses eight transmitters instead of the usual single transmitter to avoid the signal dropouts. The team tested this method with 31 drug-resistant epilepsy patients to assess whether the parallel transmit 7T scanner could outperform conventional 3T scanners in detecting brain lesions. Their findings revealed that the parallel transmit 7T scanner uncovered previously undetected structural lesions in nine patients. It also confirmed suspected lesions identified with the 3T scanner in four patients, and showed that suspected lesions in another four patients were not present. In more than half of the cases (57%), the parallel transmit 7T scans provided clearer images than the standard single-transmit 7T scans, while the remaining cases produced equally clear images.

Single-transmit scanners never surpassed the performance of parallel transmit scanners. Based on these results, the management of epilepsy was altered for more than half of the patients (18 patients, or 58%). Nine patients were offered surgery to remove the lesions, and one was recommended for laser interstitial thermal therapy, a procedure that uses heat to eliminate the lesion. For three patients, the scans revealed more complex lesions, which meant surgery was no longer an option. Five patients with larger or differently located lesions were offered stereotactic electroencephalography (sEEG), a procedure involving electrodes inserted into the brain to pinpoint the lesions. While sEEG is typically not used due to its cost and invasiveness, the detailed 7T scans made it feasible for the patients most likely to benefit from it. When patients were asked about their experience with the procedure, they reported only minor and occasional discomfort, such as dizziness when entering the scanner and increased claustrophobia due to the head coil. This suggests that parallel transmit 7T MRI is generally well tolerated by patients.

“Having epilepsy that doesn’t respond to anti-seizure medications can have a huge impact on patients’ lives, often affecting their independence and their ability to maintain a job. We know we can cure many of these patients, but that requires us to be able to pinpoint exactly where in the brain is the root of their seizures,” said Dr. Thomas Cope from the University’s Department of Clinical Neurosciences, and a Consultant Neurologist at CUH. “7T scanners have shown promise over the past few years since their introduction, and now, thanks to this new technique, more epilepsy patients will be eligible for life-changing surgery.”

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75 (144.95849609375): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

76 (51.975250244141): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (29.802322387695): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (50.067901611328): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (62.942504882812): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (60.081481933594): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (33.140182495117): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

89 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

90 (72.956085205078): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804428 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804428 AND published='1' LIMIT 1

91 (736.95182800293): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804428 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804428 AND published='1' LIMIT 1

92 (82.969665527344): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294804428 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

93 (94.890594482422): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804428 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804428 AND published='1' LIMIT 1

94 (46.014785766602): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804428 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804428 AND published='1' LIMIT 1

95 (782.01293945312): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294804428 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

96 (573.87351989746): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

97 (322.10350036621): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

98 (92.029571533203): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804428 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804428 AND published='1' LIMIT 1

99 (141.14379882812): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804428 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804428 AND published='1' LIMIT 1

100 (69.141387939453): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804428 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804428 AND published='1' LIMIT 1

101 (37.908554077148): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804428 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804428 AND published='1' LIMIT 1

102 (52.928924560547): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804428 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804428 AND published='1' LIMIT 1

103 (144.00482177734): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804428 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804428 AND published='1' LIMIT 1

104 (60.081481933594): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804428 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804428 AND published='1' LIMIT 1

105 (41.961669921875): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804428 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804428 AND published='1' LIMIT 1

106 (177.86026000977): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

107 (!!!!! 50404.787063599): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

108 (442.0280456543): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294804428 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294804428 AND type='deeppockets_item' AND published='1' LIMIT 1

109 (!!!!! 18481.016159058): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

110 (81.062316894531): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

111 (187.15858459473): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

112 (118.01719665527): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

113 (144.00482177734): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

114 (39.100646972656): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

115 (117.06352233887): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

116 (75.101852416992): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

117 (139.95170593262): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

118 (72.956085205078): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

119 (274.8966217041): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804428 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

120 (110.14938354492): SELECT name FROM jos_deeppockets WHERE id=212

121 (35.04753112793): SELECT name FROM jos_deeppockets WHERE id=212

122 (591.99333190918): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

123 (536.91864013672): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

124 (65.088272094727): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804428 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804428 AND published='1' LIMIT 1

125 (42.915344238281): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804428 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804428 AND published='1' LIMIT 1

126 (!!!!! 7596.0159301758): TRUNCATE TABLE jos_trademed_module

127 (126.12342834473): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294804428 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

128 (!!!!! 1024.9614715576): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804428 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

129 (83.92333984375): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804428 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

130 (92.983245849609): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804428 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804428 AND published='1' LIMIT 1

131 (66.041946411133): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804428 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804428 AND published='1' LIMIT 1

132 (!!!!! 1318.9315795898): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

133 (76.055526733398): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804428 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804428 AND published='1' LIMIT 1

134 (55.789947509766): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804428 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804428 AND published='1' LIMIT 1

135 (151.8726348877): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294804428 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294804428 AND type='deeppockets_item' AND published='1' LIMIT 1

136 (59.127807617188): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

137 (37.908554077148): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

138 (47.922134399414): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

139 (162.83988952637): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804428 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804428 AND published='1' LIMIT 1

140 (57.93571472168): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804428 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804428 AND published='1' LIMIT 1

141 (105.14259338379): select jos_twitters.link from jos_twitters where cat=10

142 (27.179718017578): select jos_facebook.link from jos_facebook where cat=10

143 (31.948089599609): select jos_google_plus.link from jos_google_plus where cat=10

144 (26.941299438477): select jos_linkedin.link from jos_linkedin where cat=10

145 (277.04238891602): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

146 (980.85403442383): insert into jos_banners_delta values (14615,'2025-06-21 01:13:11','216.73.216.120','view'),(14202,'2025-06-21 01:13:11','216.73.216.120','view'),(14203,'2025-06-21 01:13:11','216.73.216.120','view')

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