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27 Jul 2025 - 30 Jul 2025

AAPM 2025 - 67th Annual Meeting & Exhibition of the American Association of Physicists in Medicine

Photon Counting Detectors Promise Fast Color X-Ray Images

By MedImaging International staff writers
Posted on 26 Feb 2025

Image: Phase contrast and color X-ray imaging system used in the research (Photo courtesy of University of Houston)

For many years, healthcare professionals have depended on traditional 2D X-rays to diagnose common bone fractures, though small fractures or soft tissue damage, such as cancers, can often be missed. MRI scans, while more effective, are expensive, time-consuming, and not always suitable for routine screening. Now, a new 3D technology promises to transform medical imaging, providing a faster, more accurate, and more affordable alternative to conventional diagnostic methods.

Researchers from the University of Houston (Houston, TX, USA) have demonstrated how photon-counting detectors combined with innovative algorithms enable more precise 3D visualization of various tissues and contrast agents. These detectors capture X-rays at multiple energy levels simultaneously, helping to differentiate materials within the body. Currently, X-rays used in medical facilities and industries capture incoming photons as a whole, similar to how white light contains all the colors, without separating them. While traditional X-rays can distinguish differences in density, such as bone from soft tissue, they can't identify the specific materials inside the body.

The photon-counting detectors developed by the team can separate X-ray photons based on their energy levels, much like a prism splits white light into its component colors. This ability enables the identification of specific materials, such as aluminum, plastic, iodine, or contrast agents like gadolinium used in medical imaging. This advancement could significantly improve cancer detection, for instance, by visualizing the accumulation of different contrast agents targeting a tumor and inflammation. Currently, while bright areas in images can be seen, it is often difficult to identify what they represent. This new technology, discussed in a paper featured on the cover of Journal of Medical Imaging, offers a clearer, more quantitative analysis that would allow clinicians to not only see what's inside the body but also identify the materials present and their quantities.

However, even with this enhanced detection, some materials share similar X-ray properties, making it difficult to distinguish more than two or three materials at once. This challenge is further complicated by errors in the detectors when separating photons by energy levels. To address this, the research team has developed a method to compensate for these detector distortions by calibrating the detectors using known materials. Once calibrated, the data can be processed using the novel algorithm to accurately decompose an image into its constituent materials. This multi-step process improves accuracy, using the same CT data collected. Although significant work remains before these advanced detectors can be used widely, the research team is collaborating with industry partners in Europe to develop larger versions of these detectors and refine their performance.

“We’re still in the research and development phase,” said Mini Das, Moores professor at UH’s College of Natural Sciences and Mathematics and Cullen College of Engineering, who developed the 3D solution. “Right now, the detectors are small, and we need to refine their measurement accuracy. But once we solve those challenges, we can begin testing in real-world medical and industrial settings.”

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85 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (41.007995605469): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (38.862228393555): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (39.100646972656): SELECT show_live FROM jos_com_show_setting LIMIT 1

89 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

90 (103.95050048828): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804165 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804165 AND published='1' LIMIT 1

91 (70.095062255859): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804165 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804165 AND published='1' LIMIT 1

92 (79.154968261719): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294804165 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

93 (97.990036010742): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804165 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804165 AND published='1' LIMIT 1

94 (67.949295043945): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804165 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804165 AND published='1' LIMIT 1

95 (632.04765319824): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294804165 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

96 (533.10394287109): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

97 (319.9577331543): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

98 (77.009201049805): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804165 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804165 AND published='1' LIMIT 1

99 (82.969665527344): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804165 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804165 AND published='1' LIMIT 1

100 (56.028366088867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804165 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804165 AND published='1' LIMIT 1

101 (38.862228393555): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804165 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804165 AND published='1' LIMIT 1

102 (42.915344238281): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804165 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804165 AND published='1' LIMIT 1

103 (36.954879760742): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804165 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804165 AND published='1' LIMIT 1

104 (41.961669921875): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804165 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804165 AND published='1' LIMIT 1

105 (34.093856811523): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804165 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804165 AND published='1' LIMIT 1

106 (259.8762512207): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

107 (!!!!! 23384.094238281): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

108 (561.95259094238): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294804165 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294804165 AND type='deeppockets_item' AND published='1' LIMIT 1

109 (!!!!! 7006.1683654785): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

110 (95.129013061523): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

111 (318.05038452148): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

112 (70.095062255859): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

113 (249.86267089844): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

114 (52.928924560547): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

115 (187.15858459473): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

116 (38.862228393555): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

117 (185.01281738281): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

118 (41.007995605469): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

119 (295.87745666504): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804165 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

120 (158.07151794434): SELECT name FROM jos_deeppockets WHERE id=211

121 (58.889389038086): SELECT name FROM jos_deeppockets WHERE id=211

122 (607.01370239258): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

123 (502.8247833252): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

124 (184.05914306641): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804165 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804165 AND published='1' LIMIT 1

125 (69.141387939453): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804165 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804165 AND published='1' LIMIT 1

126 (!!!!! 7776.0219573975): TRUNCATE TABLE jos_trademed_module

127 (80.82389831543): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294804165 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

128 (823.02093505859): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804165 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

129 (55.074691772461): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804165 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

130 (71.048736572266): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804165 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804165 AND published='1' LIMIT 1

131 (43.869018554688): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804165 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804165 AND published='1' LIMIT 1

132 (!!!!! 1153.9459228516): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

133 (58.889389038086): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804165 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804165 AND published='1' LIMIT 1

134 (39.815902709961): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804165 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804165 AND published='1' LIMIT 1

135 (30.994415283203): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294804165 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294804165 AND type='deeppockets_item' AND published='1' LIMIT 1

136 (28.133392333984): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

137 (26.941299438477): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

138 (27.894973754883): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

139 (289.2017364502): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804165 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804165 AND published='1' LIMIT 1

140 (46.014785766602): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804165 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804165 AND published='1' LIMIT 1

141 (104.90417480469): select jos_twitters.link from jos_twitters where cat=10

142 (26.941299438477): select jos_facebook.link from jos_facebook where cat=10

143 (26.941299438477): select jos_google_plus.link from jos_google_plus where cat=10

144 (27.179718017578): select jos_linkedin.link from jos_linkedin where cat=10

145 (280.14183044434): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

146 (!!!!! 1040.9355163574): insert into jos_banners_delta values (14615,'2025-06-21 02:05:43','216.73.216.120','view'),(14202,'2025-06-21 02:05:43','216.73.216.120','view'),(14203,'2025-06-21 02:05:43','216.73.216.120','view')

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