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27 Jul 2025 - 30 Jul 2025

AAPM 2025 - 67th Annual Meeting & Exhibition of the American Association of Physicists in Medicine

AI-Powered Chest X-Ray Detects Pulmonary Nodules Three Years Before Lung Cancer Symptoms

By MedImaging International staff writers
Posted on 14 Oct 2024

Image: The study showed that the qXR chest X-ray AI solution can detect pulmonary nodules much earlier than symptoms appear (Photo courtesy of Qure.ai)

Lung cancer has one of the worst survival rates among all cancers, with more than two-thirds of patients diagnosed at an advanced stage, making curative treatment no longer viable. The issue of missed lung cancer cases presents a significant concern for clinicians and poses a major medicolegal challenge, as missed nodules that develop into lung cancer are the third most frequent reason for malpractice claims. Now, a new study has shown that artificial intelligence (AI)--powered chest X-ray interpretation can be used to detect pulmonary nodules which could evolve into early-stage lung cancer long before symptoms emerge. The study, through its interim findings, revealed an average diagnostic delay of nearly three years from the first abnormal chest X-ray.

The study was conducted at the Phrapokklao Hospital’s Cancer Centre of Excellence (Bangkok, Thailand) using the qXR chest X-ray AI solution from Qure.ai (New York, NY, USA). The study retrospectively reviewed and assessed chest X-ray images of newly diagnosed lung cancer patients over a one-year period using qXR. Missed lung cancer cases were identified as those that went undetected in the original report six months prior to a confirmed lung cancer diagnosis. The results showed that 18% of patient cases had missed lung cancer diagnoses, with an average diagnostic delay of nearly three years (32.3 months), ranging from a maximum of over eight years (96 months) to a minimum of eight months. Half of these cases were 'incidentally detected,' as the chest X-rays were taken for non-respiratory symptoms during routine health check-ups.

"In most Thai government hospitals, chest X-rays are interpreted by non-radiologists. However, in community hospitals, there are often no radiologists available to read chest X-rays at all. By overlaying specialist AI to read all cases, we can support clinicians in detecting incidental high-risk nodules that may lead to lung cancer,” said Dr. Passakorn Wanchaijiraboon, Medical Oncologist and Deputy Director at Phrapokklao Hospital’s Cancer Centre of Excellence, who led the study. “This approach can streamline decision-making and potentially improve patient survival through the earlier diagnosis of cancer. The implementation of CXR AI is particularly beneficial in the context of community hospitals, where it can significantly enhance diagnostic capabilities in the absence of on-site radiologists.”

"This is an exciting evidence example that underscores the transformative potential of AI in the fight against lung cancer,” added Bhargava Reddy, Chief Business Officer, Oncology at Qure.ai. "Overlaying AI on chest X-rays casts the net wider by proactively triaging patients for the risk of lung cancer. It goes beyond people with symptoms or qualifying for screening initiatives based on age or smoking history, to currently invisible and unprofiled patient populations thus detecting lung cancers earlier.”

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84 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

89 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

90 (102.99682617188): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802751 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802751 AND published='1' LIMIT 1

91 (90.122222900391): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802751 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802751 AND published='1' LIMIT 1

92 (86.069107055664): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294802751 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

93 (102.04315185547): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802751 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802751 AND published='1' LIMIT 1

94 (65.088272094727): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802751 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802751 AND published='1' LIMIT 1

95 (632.04765319824): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294802751 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

96 (772.95303344727): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

97 (519.0372467041): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

98 (164.03198242188): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802751 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802751 AND published='1' LIMIT 1

99 (89.883804321289): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802751 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802751 AND published='1' LIMIT 1

100 (68.902969360352): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802751 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802751 AND published='1' LIMIT 1

101 (67.949295043945): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802751 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802751 AND published='1' LIMIT 1

102 (71.048736572266): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802751 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802751 AND published='1' LIMIT 1

103 (50.067901611328): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802751 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802751 AND published='1' LIMIT 1

104 (68.902969360352): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802751 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802751 AND published='1' LIMIT 1

105 (54.836273193359): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802751 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802751 AND published='1' LIMIT 1

106 (390.05279541016): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

107 (!!!!! 27590.990066528): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

108 (669.95620727539): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294802751 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294802751 AND type='deeppockets_item' AND published='1' LIMIT 1

109 (!!!!! 10382.175445557): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

110 (118.97087097168): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

111 (394.10591125488): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

112 (55.074691772461): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

113 (479.93659973145): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

114 (72.956085205078): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

115 (169.03877258301): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

116 (44.107437133789): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

117 (151.15737915039): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

118 (46.968460083008): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

119 (363.11149597168): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802751 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

120 (187.15858459473): SELECT name FROM jos_deeppockets WHERE id=211

121 (46.014785766602): SELECT name FROM jos_deeppockets WHERE id=211

122 (813.00735473633): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

123 (681.16188049316): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

124 (101.08947753906): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802751 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802751 AND published='1' LIMIT 1

125 (71.048736572266): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802751 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802751 AND published='1' LIMIT 1

126 (!!!!! 5437.1356964111): TRUNCATE TABLE jos_trademed_module

127 (151.15737915039): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294802751 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

128 (643.96858215332): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802751 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

129 (79.870223999023): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802751 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

130 (97.990036010742): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802751 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802751 AND published='1' LIMIT 1

131 (62.942504882812): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802751 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802751 AND published='1' LIMIT 1

132 (!!!!! 1574.0394592285): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

133 (88.930130004883): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802751 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802751 AND published='1' LIMIT 1

134 (61.988830566406): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802751 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802751 AND published='1' LIMIT 1

135 (56.028366088867): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294802751 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294802751 AND type='deeppockets_item' AND published='1' LIMIT 1

136 (44.822692871094): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

137 (43.153762817383): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

138 (48.87580871582): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

139 (160.93254089355): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802751 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802751 AND published='1' LIMIT 1

140 (74.863433837891): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802751 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802751 AND published='1' LIMIT 1

141 (140.90538024902): select jos_twitters.link from jos_twitters where cat=10

142 (37.908554077148): select jos_facebook.link from jos_facebook where cat=10

143 (36.001205444336): select jos_google_plus.link from jos_google_plus where cat=10

144 (35.04753112793): select jos_linkedin.link from jos_linkedin where cat=10

145 (378.13186645508): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

146 (!!!!! 1017.8089141846): insert into jos_banners_delta values (14615,'2025-06-21 01:58:36','216.73.216.120','view'),(14202,'2025-06-21 01:58:36','216.73.216.120','view'),(14203,'2025-06-21 01:58:36','216.73.216.120','view')

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