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AAPM 2025 - 67th Annual Meeting & Exhibition of the American Association of Physicists in Medicine

AI Tool Offers Opportunistic Screening for Heart Disease Using Repurposed CT Scans

By MedImaging International staff writers
Posted on 05 Dec 2024

Image: AI-enabled analysis of images meant to catch one disease can reveal others (Photo courtesy of 123RF)

In the field of medical imaging, the term "opportunistic screening" refers to the repurposing of existing medical images by radiologists to diagnose illnesses beyond what the scan was originally meant to find. In yet another example of the trend in "opportunistic screening," a new study has shown how an artificial intelligence (AI) tool can be applied to computed tomography (CT) scans—initially performed to detect tumors, bleeding, or infections—to also reveal calcium buildup in arteries, a key indicator of advancing cardiovascular disease. This new discovery supports prior findings published in September in the journal Bone, where opportunistic screening was used to detect bone loss, also known as osteoporosis.

In the study presented at RSNA 2024, researchers from NYU Langone Health (New York, NY, USA) reanalyzed a large set of abdominal CT scans originally taken for various reasons. The goal was to assess a section of the aorta, the large artery that runs from the heart through the abdomen. Using this data from routine scans, the team applied AI to quantify the amount of calcium in the aorta, assign a standard score to the calcification level, and predict the likelihood of a major cardiovascular event, such as a heart attack or blockage. The study analyzed 3,662 CT scans, conducted between 2013 and 2023, from older adults who had both an abdominal scan (which captured part of the aorta) and a dedicated CT of their coronary arteries.

The researchers discovered that by measuring the calcium levels in the aorta from the abdominal scans, AI was able to predict coronary artery calcification and the risk of major cardiovascular events. This suggests that an abdominal CT scan alone could potentially be used to predict heart attacks or other cardiovascular conditions. Participants with detectable aortic calcification were found to be 2.2 times more likely to experience a major heart attack, stroke, or require procedures to restore heart blood flow within three years of monitoring. This outcome was observed in 324 of the study participants. Additionally, the study uncovered early signs of arterial calcium buildup in 29% of participants who were previously thought to have no such condition.

"Instead of relying on dedicated CT scans of coronary arteries, which are rare and not always covered by insurance, to find potentially fatal heart disease, we seek to use AI to help screen abdominal CT scans that are done for many reasons to opportunistically catch heart disease more often and earlier," said study senior investigator Miriam Bredella, MD, MBA. Bredella is the Bernard and Irene Schwartz Professor of Radiology and director of the Clinical and Translational Science Institute at NYU Grossman School of Medicine. "Our research demonstrates that opportunistic screening could help with diagnosing and treating osteoporosis in vulnerable groups who are at greater risk of the disease, in particular, the elderly and those who smoke. This work establishes the foundation for using opportunistic screening to address the lack of access to osteoporosis and heart disease prevention, as well as to screening for cancer and diabetes."

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81 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

89 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

90 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (56.982040405273): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (70.810317993164): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803337 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803337 AND published='1' LIMIT 1

93 (41.007995605469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803337 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803337 AND published='1' LIMIT 1

94 (54.836273193359): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294803337 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

95 (106.8115234375): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803337 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803337 AND published='1' LIMIT 1

96 (63.896179199219): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803337 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803337 AND published='1' LIMIT 1

97 (415.08674621582): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294803337 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

98 (619.88830566406): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

99 (324.01084899902): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

100 (83.92333984375): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803337 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803337 AND published='1' LIMIT 1

101 (57.93571472168): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803337 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803337 AND published='1' LIMIT 1

102 (122.0703125): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803337 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803337 AND published='1' LIMIT 1

103 (40.054321289062): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803337 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803337 AND published='1' LIMIT 1

104 (85.830688476562): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803337 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803337 AND published='1' LIMIT 1

105 (41.007995605469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803337 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803337 AND published='1' LIMIT 1

106 (56.028366088867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803337 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803337 AND published='1' LIMIT 1

107 (37.908554077148): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803337 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803337 AND published='1' LIMIT 1

108 (232.93495178223): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

109 (!!!!! 18610.954284668): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

110 (642.06123352051): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294803337 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294803337 AND type='deeppockets_item' AND published='1' LIMIT 1

111 (!!!!! 7647.9911804199): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

112 (87.976455688477): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

113 (329.97131347656): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

114 (55.074691772461): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

115 (258.9225769043): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

116 (45.7763671875): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

117 (209.80834960938): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

118 (37.908554077148): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

119 (196.93374633789): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

120 (38.862228393555): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

121 (261.06834411621): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803337 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

122 (119.92454528809): SELECT name FROM jos_deeppockets WHERE id=215

123 (36.954879760742): SELECT name FROM jos_deeppockets WHERE id=215

124 (525.95138549805): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))215((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

125 (864.02893066406): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))215((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

126 (71.048736572266): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803337 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803337 AND published='1' LIMIT 1

127 (46.014785766602): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803337 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803337 AND published='1' LIMIT 1

128 (!!!!! 7406.9499969482): TRUNCATE TABLE jos_trademed_module

129 (116.82510375977): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294803337 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

130 (962.97264099121): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803337 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

131 (82.969665527344): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803337 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

132 (61.988830566406): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803337 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803337 AND published='1' LIMIT 1

133 (45.061111450195): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803337 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803337 AND published='1' LIMIT 1

134 (!!!!! 1295.0897216797): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

135 (75.101852416992): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803337 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803337 AND published='1' LIMIT 1

136 (51.975250244141): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803337 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803337 AND published='1' LIMIT 1

137 (56.982040405273): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294803337 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294803337 AND type='deeppockets_item' AND published='1' LIMIT 1

138 (35.04753112793): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=215 or channel_id is null)

139 (31.948089599609): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=215 or channel_id is null)

140 (33.140182495117): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

141 (149.01161193848): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803337 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803337 AND published='1' LIMIT 1

142 (61.988830566406): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803337 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803337 AND published='1' LIMIT 1

143 (174.99923706055): select jos_twitters.link from jos_twitters where cat=10

144 (33.855438232422): select jos_facebook.link from jos_facebook where cat=10

145 (31.948089599609): select jos_google_plus.link from jos_google_plus where cat=10

146 (35.04753112793): select jos_linkedin.link from jos_linkedin where cat=10

147 (335.2165222168): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14202,14203)

148 (!!!!! 1658.9164733887): insert into jos_banners_delta values (14202,'2025-06-21 01:11:45','216.73.216.120','view'),(14203,'2025-06-21 01:11:45','216.73.216.120','view')

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