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27 Jul 2025 - 30 Jul 2025

AAPM 2025 - 67th Annual Meeting & Exhibition of the American Association of Physicists in Medicine

First-Of-Its-Kind AI-Driven Brain Imaging Platform to Better Guide Stroke Treatment Options

By MedImaging International staff writers
Posted on 05 Mar 2025

Image: Composite samples of the MRI images that AStrID will draw on to advance research that promises to optimize stroke rehabilitation (Photo courtesy of GU School of Medicine)

Each year, approximately 800,000 people in the U.S. experience strokes, with marginalized and minoritized groups being disproportionately affected. Strokes vary in terms of size and location within the brain, making recovery studies particularly challenging. Each survivor faces different difficulties depending on where the stroke occurred and its severity, such as weakness on one side of the body or difficulty speaking. Some treatments designed to aid recovery may only benefit individuals with strokes in specific areas of the brain. Until now, it has been difficult to quickly identify individuals based on the size and location of their stroke in order to test these treatments. Now, a new artificial intelligence (AI)-driven brain imaging platform is expected to significantly improve treatment guidance and transform stroke recovery research.

A group of stroke physician-scientists at Georgetown University Medical Center (Washington, D.C., USA) has launched the Acute Stroke Imaging Database (AStrID), an initiative that scans MRI images to automatically identify the type and location of strokes in approximately 5,000 acute stroke cases seen annually at the MedStar Health system (Columbia, MD, USA). MedStar Health serves a diverse patient population, representing a wide range of socioeconomic, cultural, and racial backgrounds from 10 hospitals in Maryland, Washington, D.C., and Virginia. This makes it an ideal sample group to reflect the U.S. population. AStrID is part of a larger stroke registry that reviews electronic medical records of stroke patients to aid in research efforts. By allowing researchers to group stroke survivors based on the specifics of their strokes, AStrID enables the identification of the most appropriate clinical trials and treatments for each patient, thereby enhancing the reliability of stroke recovery studies.

The AStrID development process began with hundreds of training images in which the researchers manually identified the location of the strokes. They then fed this information into the AStrID learning algorithm, which, based on these training sets, can detect stroke locations in new MRI images. Using the platform’s search tool, researchers can pinpoint images in AStrID that display strokes in specific brain regions. In the next year, the researchers aim to include up to 20,000 stroke images in AStrID, potentially making it the largest stroke imaging repository globally. To protect patient confidentiality, AStrID removes all identifying details from the MRIs before processing them, storing only the digital images that mark the stroke locations, not the actual MRI scans. These images are kept separately from the electronic medical records within the broader stroke registry, with access to the two being restricted and linked only through anonymized codes.

The research team’s primary focus is on helping patients recover language abilities post-stroke. Approximately one-third of stroke survivors experience aphasia, a condition that impairs language use. After a stroke, the brain has the capacity to reorganize itself and form new connections, a process known as brain plasticity, which enables recovery of lost functions over time. Enhancing brain plasticity could improve recovery from aphasia, but the pattern of this plasticity varies based on the size and location of each stroke. With AStrID, the researchers can identify groups of patients with similar stroke profiles, helping them uncover previously hidden patterns of brain plasticity that could potentially be targeted by new treatments to enhance recovery.

“Disparities in access to services affect every phase of stroke care,” said Peter E. Turkeltaub, MD, PhD, director of the Cognitive Recovery Lab at Georgetown University and the Aphasia Clinic at MedStar National Rehabilitation Hospital. “AStrID and the broader stroke registry can help us understand how these disparities affect outcomes. We can identify groups of people who we’d expect to have similar recoveries because they have very similar strokes, and then assess if access to rehabilitation or other stroke services changes their recovery. That will help us find the people who would benefit most from better stroke services to improve equity and outcomes.”

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75 (31.948089599609): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

76 (49.114227294922): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

89 (31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1

90 (76.055526733398): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804233 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804233 AND published='1' LIMIT 1

91 (43.869018554688): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804233 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804233 AND published='1' LIMIT 1

92 (57.220458984375): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294804233 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

93 (69.141387939453): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804233 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804233 AND published='1' LIMIT 1

94 (49.829483032227): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804233 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804233 AND published='1' LIMIT 1

95 (491.85752868652): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294804233 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

96 (584.12551879883): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

97 (417.94776916504): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

98 (76.055526733398): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804233 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804233 AND published='1' LIMIT 1

99 (47.922134399414): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804233 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804233 AND published='1' LIMIT 1

100 (48.87580871582): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804233 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804233 AND published='1' LIMIT 1

101 (41.007995605469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804233 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804233 AND published='1' LIMIT 1

102 (44.107437133789): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804233 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804233 AND published='1' LIMIT 1

103 (38.14697265625): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804233 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804233 AND published='1' LIMIT 1

104 (50.067901611328): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804233 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804233 AND published='1' LIMIT 1

105 (38.862228393555): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804233 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804233 AND published='1' LIMIT 1

106 (277.99606323242): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

107 (!!!!! 19808.053970337): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

108 (546.93222045898): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294804233 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294804233 AND type='deeppockets_item' AND published='1' LIMIT 1

109 (!!!!! 8334.1598510742): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

110 (80.108642578125): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

111 (322.10350036621): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

112 (46.968460083008): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

113 (206.94732666016): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

114 (45.061111450195): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

115 (242.94853210449): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

116 (39.815902709961): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

117 (191.92695617676): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

118 (36.954879760742): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

119 (313.04359436035): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804233 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

120 (156.87942504883): SELECT name FROM jos_deeppockets WHERE id=212

121 (48.160552978516): SELECT name FROM jos_deeppockets WHERE id=212

122 (591.03965759277): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

123 (488.9965057373): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

124 (164.98565673828): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804233 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804233 AND published='1' LIMIT 1

125 (51.975250244141): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804233 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804233 AND published='1' LIMIT 1

126 (!!!!! 8805.0365447998): TRUNCATE TABLE jos_trademed_module

127 (236.03439331055): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294804233 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

128 (901.22222900391): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804233 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

129 (58.174133300781): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804233 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

130 (52.928924560547): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804233 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804233 AND published='1' LIMIT 1

131 (38.862228393555): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804233 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804233 AND published='1' LIMIT 1

132 (!!!!! 1189.9471282959): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

133 (72.002410888672): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804233 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804233 AND published='1' LIMIT 1

134 (59.843063354492): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804233 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804233 AND published='1' LIMIT 1

135 (41.007995605469): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294804233 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294804233 AND type='deeppockets_item' AND published='1' LIMIT 1

136 (29.802322387695): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

137 (27.894973754883): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

138 (29.087066650391): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

139 (186.20491027832): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804233 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804233 AND published='1' LIMIT 1

140 (65.088272094727): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294804233 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294804233 AND published='1' LIMIT 1

141 (179.05235290527): select jos_twitters.link from jos_twitters where cat=10

142 (41.007995605469): select jos_facebook.link from jos_facebook where cat=10

143 (35.04753112793): select jos_google_plus.link from jos_google_plus where cat=10

144 (36.001205444336): select jos_linkedin.link from jos_linkedin where cat=10

145 (294.92378234863): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

146 (!!!!! 1106.9774627686): insert into jos_banners_delta values (14615,'2025-06-21 01:18:58','216.73.216.120','view'),(14202,'2025-06-21 01:18:58','216.73.216.120','view'),(14203,'2025-06-21 01:18:58','216.73.216.120','view')

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