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Nanoparticles Demonstrate Use as Injectable Marker

By MedImaging International staff writers
Posted on 01 Aug 2017

Image: An illustration of a multifunctional Tantalum oxide/silica core/shell nanoparticles (TSNs) with a radiopaque core for X-ray imaging, conjugated fluorescent dye for fluorescent imaging, a dense core material with a high sound-scattering effect for ultrasound imaging, and a silica surface for adhesive property (Photo courtesy of Nature Communications).

Researchers have found a new tissue adhesive that can be detected by clinical imaging modalities, and is also extremely biocompatible for minimally invasive procedures.

The injectable biocompatible radiopaque Tantalum oxide/Silica core/shell Nanoparticles (TSN) were not only very adhesive, but also demonstrated high-contrast for real-time imaging. Adhesives are becoming a convenient alternative to staples and sutures for reconnecting injured tissues and closing wounds following trauma or surgery, especially in minimally invasive procedures.

The results were published online in the July 19, 2017, issue of the journal Nature Communications by the researchers from the Seoul National University (Seoul, South Korea) and other academic and medical institutions in South Korea. The TSN particles cause significantly less inflammation, and cellular toxicity than CyanoAcrylate and Lipiodol (CA-Lp), imageable tissue adhesives.

TSNs could be used for image-guided procedures such as needle biopsy, catheter-directed embolotherapy, percutaneous angioplasty, vertebroplasty and Radio Frequency (RF) / microwave ablation. These minimally invasive procedures are increasingly used to replacing conventional surgery to control internal bleeding, to perform organ biopsies, and for vessel occlusion for example.

The researchers were able to demonstrate that the TSN glue was clearly visualized by X-Ray fluoroscopy, Computed Tomography (CT), Magnetic Resonance Imaging (MRI), ultrasound, and other clinical modalities. Tantalum oxide is inert, takes time to biodegrade in the body, and is normally only required in very small quantities in image-guided procedures, and remain in the target area without any extreme severe adverse reactions.

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63 (!!!!! 2496.0041046143): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

64 (!!!!! 1127.0046234131): SELECT fid FROM jos_deeppockets WHERE id=294770225 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294770225 AND published='1' LIMIT 1

65 (421.04721069336): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=211 ORDER BY `ordering`

66 (!!!!! 2699.1367340088): select jos_twitters.link from jos_twitters where cat=10

67 (56.028366088867): select jos_facebook.link from jos_facebook where cat=10

68 (38.862228393555): select jos_google_plus.link from jos_google_plus where cat=10

69 (36.954879760742): select jos_linkedin.link from jos_linkedin where cat=10

70 (417.94776916504): SELECT fid FROM jos_deeppockets WHERE id=294770225 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294770225 AND published='1' LIMIT 1

71 (!!!!! 2009.1533660889): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=211 ORDER BY `ordering`

72 (!!!!! 7613.8973236084): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294770225 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

73 (583.17184448242): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294770225 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

74 (92.983245849609): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

75 (!!!!! 9078.9794921875): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (!!!!! 3933.9065551758): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (!!!!! 5220.890045166): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (84.877014160156): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (32.186508178711): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

89 (67.949295043945): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294770225 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

90 (30.994415283203): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294770225 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

91 (35.04753112793): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

92 (!!!!! 2275.2285003662): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (43.869018554688): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (255.10787963867): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (366.9261932373): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (!!!!! 2655.029296875): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (53.882598876953): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (!!!!! 2797.1267700195): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (217.19932556152): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (326.15661621094): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

105 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

106 (!!!!! 1220.9415435791): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294770225 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294770225 AND published='1' LIMIT 1

107 (353.81317138672): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294770225 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294770225 AND published='1' LIMIT 1

108 (519.99092102051): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294770225 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

109 (!!!!! 1026.1535644531): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294770225 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

110 (!!!!! 3498.0773925781): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294770225 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294770225 AND published='1' LIMIT 1

111 (195.02639770508): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294770225 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294770225 AND published='1' LIMIT 1

112 (707.14950561523): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294770225 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

113 (792.9801940918): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294770225 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

114 (381.9465637207): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294770224 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

115 (474.92980957031): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294770224 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

116 (!!!!! 1167.0589447021): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

117 (560.99891662598): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

118 (!!!!! 2063.9896392822): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294770225 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294770225 AND published='1' LIMIT 1

119 (270.84350585938): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294770225 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294770225 AND published='1' LIMIT 1

120 (870.94306945801): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294770225 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294770225 AND published='1' LIMIT 1

121 (291.10908508301): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294770225 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294770225 AND published='1' LIMIT 1

122 (488.9965057373): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294770225 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294770225 AND published='1' LIMIT 1

123 (233.88862609863): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294770225 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294770225 AND published='1' LIMIT 1

124 (197.8874206543): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294770225 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294770225 AND published='1' LIMIT 1

125 (367.87986755371): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294770225 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294770225 AND published='1' LIMIT 1

126 (304.9373626709): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

127 (!!!!! 42137.145996094): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

128 (492.09594726562): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294770225 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294770225 AND type='deeppockets_item' AND published='1' LIMIT 1

129 (!!!!! 17556.90574646): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

130 (58.174133300781): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

131 (190.97328186035): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

132 (36.001205444336): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

133 (!!!!! 3333.8069915771): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

134 (571.01249694824): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

135 (185.01281738281): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

136 (44.822692871094): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

137 (149.96528625488): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

138 (33.855438232422): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

139 (571.96617126465): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294770225 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

140 (339.98489379883): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294770225 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

141 (!!!!! 1258.8500976562): SELECT name FROM jos_deeppockets WHERE id=211

142 (37.908554077148): SELECT name FROM jos_deeppockets WHERE id=211

143 (512.83836364746): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

144 (561.95259094238): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

145 (784.15870666504): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294770225 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294770225 AND published='1' LIMIT 1

146 (327.11029052734): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294770225 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294770225 AND published='1' LIMIT 1

147 (!!!!! 5321.0258483887): TRUNCATE TABLE jos_trademed_module

148 (!!!!! 6994.0090179443): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294770225 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

149 (!!!!! 1027.8224945068): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294770225 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

150 (!!!!! 3345.0126647949): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294770225 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

151 (478.98292541504): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294770225 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

152 (702.85797119141): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294770225 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294770225 AND published='1' LIMIT 1

153 (158.07151794434): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294770225 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294770225 AND published='1' LIMIT 1

154 (!!!!! 2768.0397033691): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

155 (659.94262695312): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294770225 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294770225 AND published='1' LIMIT 1

156 (158.78677368164): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294770225 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294770225 AND published='1' LIMIT 1

157 (!!!!! 4410.0284576416): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294770225 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294770225 AND type='deeppockets_item' AND published='1' LIMIT 1

158 (730.03768920898): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=0 or channel_id is null)

159 (47.922134399414): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=0 or channel_id is null)

160 (829.93507385254): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

161 (677.82402038574): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294770225 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294770225 AND published='1' LIMIT 1

162 (156.87942504883): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294770225 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294770225 AND published='1' LIMIT 1

163 (636.10076904297): select jos_twitters.link from jos_twitters where cat=10

164 (35.04753112793): select jos_facebook.link from jos_facebook where cat=10

165 (133.99124145508): select jos_google_plus.link from jos_google_plus where cat=10

166 (170.94612121582): select jos_linkedin.link from jos_linkedin where cat=10

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