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Study Demonstrates Radiation Risk from Digital Screening Mammography Can Be Reduced Further

By MedImaging International staff writers
Posted on 19 Jan 2016

The risk of radiation-induced breast cancer for women undergoing digital screening mammography can be reduced even more for most women by employing simple changes in screening guidelines.

The findings were published in the January 2016, issue of the Annals of Internal Medicine. The research was part of a comprehensive modeling study, undertaken by the UC Davis School of Medicine (Sacramento, CA, USA) that found minimal risk of radiation-induced breast cancer for most women from digital mammography breast cancer screening. Women with large breasts or those with breast implants, often receive extra screening, and have increased radiation exposure. Larger detectors and other new technologies can help mitigate the risk for these women.

The researchers modeled the risk of women developing radiation-induced breast cancer during their lifetime from digital screening mammography, and as a result dying from the disease. The researchers compared this to the number of breast cancer deaths that were prevented by early detection and found that screening 100,000 women aged between 50 and 74, every two years, prevented 627 deaths. The radiation from such exams, and subsequent additional diagnostics, could cause 27 cases of breast cancer, and four deaths. When women aged 40 to 74 were screened every year, an additional 100 radiation-induced breast cancers occurred, and 12 breast cancer deaths, compared to women aged 50 to 74, who were screened every two years.

The results of the study showed screening mammograms taken every two years, instead of yearly, and starting from age 50, not 40 or 45, would be safer for all women.

Diana Miglioretti, first author of the study, and Biostatistics professor at UC Davis School of Medicine, said, “For most women, the risks are very low. The one group I worry about is women with very large breasts who choose to be screened annually from ages 40 to 74. Most screening mammograms are two views per breast. Some women with large breasts need more than four views for a complete screening examination, increasing their exposure to ionizing radiation. In addition, the dose per view increases with compressed breast thickness, further increasing exposure. For the average woman, having an additional workup for an abnormal screening result offers very small additional radiation exposure. But for some women who have additional mammography views and an image-guided biopsy, the additional workup can account for a quarter of their annual radiation exposure from mammography. For the majority of women, screening mammography is very safe. And if you screen every other year between 50 and 74, that makes it safest.”

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68 (77.009201049805): SELECT fid FROM jos_deeppockets WHERE id=294762333 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294762333 AND published='1' LIMIT 1

69 (46.968460083008): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=211 ORDER BY `ordering`

70 (473.97613525391): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294762333 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (361.91940307617): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294762333 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (!!!!! 1609.8022460938): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (58.174133300781): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (99.18212890625): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (33.855438232422): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (33.140182495117): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (54.121017456055): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (61.988830566406): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (66.995620727539): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294762333 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (28.848648071289): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294762333 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (32.901763916016): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (51.021575927734): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (65.088272094727): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (94.890594482422): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294762333 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294762333 AND published='1' LIMIT 1

105 (47.922134399414): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294762333 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294762333 AND published='1' LIMIT 1

106 (51.975250244141): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294762333 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (46.968460083008): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294762333 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (70.095062255859): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294762333 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294762333 AND published='1' LIMIT 1

109 (44.107437133789): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294762333 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294762333 AND published='1' LIMIT 1

110 (70.095062255859): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294762333 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (745.05805969238): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294762333 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (576.97296142578): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (315.90461730957): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (77.009201049805): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294762333 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294762333 AND published='1' LIMIT 1

115 (56.028366088867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294762333 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294762333 AND published='1' LIMIT 1

116 (47.922134399414): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294762333 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294762333 AND published='1' LIMIT 1

117 (75.101852416992): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294762333 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294762333 AND published='1' LIMIT 1

118 (72.956085205078): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294762333 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294762333 AND published='1' LIMIT 1

119 (42.915344238281): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294762333 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294762333 AND published='1' LIMIT 1

120 (41.007995605469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294762333 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294762333 AND published='1' LIMIT 1

121 (65.088272094727): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294762333 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294762333 AND published='1' LIMIT 1

122 (335.9317779541): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 19607.067108154): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (499.96376037598): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294762333 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294762333 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 10010.957717896): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (132.08389282227): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (391.00646972656): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (58.174133300781): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (422.00088500977): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (55.074691772461): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (338.07754516602): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (51.975250244141): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (222.20611572266): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (35.04753112793): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (452.99530029297): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294762333 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (388.14544677734): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294762333 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (272.98927307129): SELECT name FROM jos_deeppockets WHERE id=211

138 (33.140182495117): SELECT name FROM jos_deeppockets WHERE id=211

139 (588.89389038086): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (439.88227844238): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (105.85784912109): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294762333 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294762333 AND published='1' LIMIT 1

142 (51.021575927734): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294762333 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294762333 AND published='1' LIMIT 1

143 (!!!!! 8852.0050048828): TRUNCATE TABLE jos_trademed_module

144 (112.05673217773): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294762333 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (53.167343139648): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294762333 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (569.10514831543): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294762333 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (56.028366088867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294762333 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (59.843063354492): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294762333 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294762333 AND published='1' LIMIT 1

149 (44.107437133789): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294762333 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294762333 AND published='1' LIMIT 1

150 (!!!!! 1221.1799621582): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (65.088272094727): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294762333 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294762333 AND published='1' LIMIT 1

152 (49.114227294922): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294762333 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294762333 AND published='1' LIMIT 1

153 (39.100646972656): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294762333 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294762333 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (33.855438232422): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

155 (30.994415283203): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

156 (36.001205444336): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (66.041946411133): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294762333 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294762333 AND published='1' LIMIT 1

158 (45.061111450195): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294762333 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294762333 AND published='1' LIMIT 1

159 (102.04315185547): select jos_twitters.link from jos_twitters where cat=10

160 (47.922134399414): select jos_facebook.link from jos_facebook where cat=10

161 (40.054321289062): select jos_google_plus.link from jos_google_plus where cat=10

162 (36.954879760742): select jos_linkedin.link from jos_linkedin where cat=10

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