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Breast Radiotherapy Reduced to More Convenient Once-Weekly Regimen Option

By MedImaging International staff writers
Posted on 16 Sep 2014

An investigational regimen of once-weekly breast irradiation following lumpectomy is more convenient to patients at a lower cost, results in better completion rates of prescribed radiation treatment, and generates cosmetic outcomes comparable to the current routine of daily radiation.

These interim findings of the five-year phase II clinical trial were presented at the Breast Cancer Symposium 2014, held in San Francisco (CA, USA), in September 2014, by Anthony E. Dragun, MD, vice chair and associate professor of radiation oncology at the University of Louisville (UofL; KY, USA).

Dr. Dragun, a radiation oncologist with University of Louisville Physicians, launched the trial three years ago at UofL’s James Graham Brown Cancer Center, a part of KentuckyOne Health and the only site offering the experimental regimen in the United States. A second KentuckyOne Health site is being planned, he noted, and is expected to begin enrolling patients in the upcoming months.

Reviewing data from Europe, in particular the United Kingdom, Dr. Dragun discovered an alternative to the currently standard daily radiation treatments prescribed to patients after a lumpectomy. Physicians in the United Kingdom and other European countries were reporting excellent results with a regimen of radiation administered once-weekly. “Instead of daily treatments for 25–30 days, five to six treatments administered once each week were being used,” he said. “I thought this regimen would give our patients here in Kentucky a great deal of access and choice, so we developed the trial and launched it in 2011.”

Approximately 150 female patients have been enrolled in the trial up to now, Dr. Dragun reported. Patients undergoing a lumpectomy following diagnosis of breast cancer are offered a choice of the current standard of daily radiation treatments or the option to enroll in the trial and receive treatment once a week. The radiotherapy dosing has been adjusted to compensate for the change in how the sessions are administered, but no adverse effects have been seen, Dr. Dragun said. “The outcomes with once-weekly treatments are absolutely in line with what we see in daily breast irradiation,” he said. “The standard of care is maintained.”

Giving women the choice of how their treatment is administered means more women complete their treatment, he said. “Finding time for daily treatments for six weeks or more just isn’t possible for many women,” Dr. Dragun stated. “Scheduling once-weekly treatments is much easier to fit into the busy lives our patients lead. We also see many patients who depend on public transportation or live in rural areas that are 30 miles or more from our center, and they have told us that they would not have been able to complete a traditional course of daily radiation treatment. Their only alternative would be a mastectomy.”

Because radiation treatment is reimbursed on a per-treatment basis, Dr. Dragun reported that the overall cost is lowered. “We have reduced the number of treatments to about one-fourth to one-third of what the current daily treatment regimen is,” he said. “[US] Medicare reimburses radiation costs on a per-treatment basis, and most private insurers do likewise. This means we’ve been able to reduce the cost by 50%–60% without jeopardizing the quality of care.”

Dr. Dragun is planning to enroll another 50 patients at the Louisville site and 30 at the future trial site. After the completion of this trial, he intends to expand into a multicenter phase III trial at facilities in other US states. “We believe the once-weekly regimen such as this will become a standard option in the next decade,” he said.

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60 (249.86267089844): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294754620 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294754620 AND published='1' LIMIT 1

61 (!!!!! 11290.788650513): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

62 (!!!!! 7885.9329223633): SELECT fid FROM jos_deeppockets WHERE id=294754620 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294754620 AND published='1' LIMIT 1

63 (!!!!! 7830.8582305908): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=211 ORDER BY `ordering`

64 (!!!!! 7683.9923858643): select jos_twitters.link from jos_twitters where cat=10

65 (!!!!! 7236.9575500488): select jos_facebook.link from jos_facebook where cat=10

66 (!!!!! 6616.8308258057): select jos_google_plus.link from jos_google_plus where cat=10

67 (!!!!! 4274.845123291): select jos_linkedin.link from jos_linkedin where cat=10

68 (!!!!! 1569.0326690674): SELECT fid FROM jos_deeppockets WHERE id=294754620 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294754620 AND published='1' LIMIT 1

69 (!!!!! 2511.0244750977): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=211 ORDER BY `ordering`

70 (!!!!! 1059.0553283691): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294754620 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (537.87231445312): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294754620 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (234.84230041504): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (!!!!! 4405.0216674805): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (608.92105102539): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (77.962875366211): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (47.922134399414): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (423.90823364258): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (58.889389038086): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (51.975250244141): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (44.107437133789): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (353.09791564941): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (108.95729064941): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (51.975250244141): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (!!!!! 3914.1178131104): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (660.18104553223): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (!!!!! 3165.0066375732): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (!!!!! 1885.1757049561): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294754620 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (91.791152954102): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294754620 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (!!!!! 1421.9284057617): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (767.94624328613): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (!!!!! 1714.9448394775): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (94.890594482422): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (57.93571472168): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (84.877014160156): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (58.889389038086): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (602.96058654785): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (!!!!! 2103.8055419922): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (!!!!! 3993.034362793): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (68.902969360352): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (!!!!! 3406.0478210449): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (138.99803161621): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (626.80244445801): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (!!!!! 3095.1499938965): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (!!!!! 1147.985458374): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294754620 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294754620 AND published='1' LIMIT 1

105 (539.77966308594): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294754620 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294754620 AND published='1' LIMIT 1

106 (370.97930908203): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294754620 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (!!!!! 1191.8544769287): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294754620 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (!!!!! 11359.930038452): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294754620 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294754620 AND published='1' LIMIT 1

109 (120.87821960449): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294754620 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294754620 AND published='1' LIMIT 1

110 (173.09188842773): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294754620 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (!!!!! 1367.0921325684): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294754620 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (!!!!! 2884.1495513916): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (!!!!! 1969.0990447998): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (!!!!! 16687.154769897): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294754620 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294754620 AND published='1' LIMIT 1

115 (!!!!! 1224.0409851074): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294754620 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294754620 AND published='1' LIMIT 1

116 (!!!!! 3756.046295166): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294754620 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294754620 AND published='1' LIMIT 1

117 (!!!!! 1466.9895172119): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294754620 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294754620 AND published='1' LIMIT 1

118 (!!!!! 2565.860748291): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294754620 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294754620 AND published='1' LIMIT 1

119 (!!!!! 1487.0166778564): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294754620 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294754620 AND published='1' LIMIT 1

120 (!!!!! 2421.1406707764): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294754620 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294754620 AND published='1' LIMIT 1

121 (137.0906829834): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294754620 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294754620 AND published='1' LIMIT 1

122 (580.0724029541): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 103666.06712341): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (!!!!! 1631.0214996338): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294754620 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294754620 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (759.12475585938): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (78.916549682617): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (995.15914916992): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (777.00614929199): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (!!!!! 1332.9982757568): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (234.84230041504): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (833.98818969727): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (755.07164001465): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (476.12190246582): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (82.969665527344): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (!!!!! 8143.9018249512): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294754620 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (!!!!! 4228.1150817871): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294754620 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (849.96223449707): SELECT name FROM jos_deeppockets WHERE id=211

138 (50.067901611328): SELECT name FROM jos_deeppockets WHERE id=211

139 (!!!!! 1057.8632354736): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (!!!!! 12927.055358887): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (!!!!! 31707.048416138): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294754620 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294754620 AND published='1' LIMIT 1

142 (!!!!! 8001.0890960693): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294754620 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294754620 AND published='1' LIMIT 1

143 (!!!!! 19623.994827271): TRUNCATE TABLE jos_trademed_module

144 (!!!!! 2445.9362030029): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294754620 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (!!!!! 3757.9536437988): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294754620 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (!!!!! 1389.9803161621): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294754620 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (185.96649169922): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294754620 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (946.044921875): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294754620 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294754620 AND published='1' LIMIT 1

149 (76.055526733398): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294754620 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294754620 AND published='1' LIMIT 1

150 (!!!!! 4615.0684356689): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (!!!!! 26242.971420288): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294754620 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294754620 AND published='1' LIMIT 1

152 (!!!!! 7977.0088195801): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294754620 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294754620 AND published='1' LIMIT 1

153 (!!!!! 8175.1346588135): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294754620 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294754620 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (!!!!! 7200.9563446045): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

155 (!!!!! 12292.146682739): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

156 (!!!!! 4518.985748291): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (!!!!! 4922.8668212891): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294754620 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294754620 AND published='1' LIMIT 1

158 (!!!!! 14601.945877075): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294754620 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294754620 AND published='1' LIMIT 1

159 (!!!!! 3420.8297729492): select jos_twitters.link from jos_twitters where cat=10

160 (!!!!! 2721.0712432861): select jos_facebook.link from jos_facebook where cat=10

161 (!!!!! 1878.023147583): select jos_google_plus.link from jos_google_plus where cat=10

162 (57.93571472168): select jos_linkedin.link from jos_linkedin where cat=10

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