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Beam-Shaping Collimator for Cancer Radiotherapy Accelerates Treatment

By MedImaging International staff writers
Posted on 17 Jul 2012

Utilizing new and faster technology, a new multileaf collimator (MLC) is expected to further improve therapy for oncology patients and speed up treatment times.

Using a combination of 160 high-resolution tungsten leaves and greatly faster leaf movement, Elekta’s (Stockholm, Sweden) new Agility MLC has the potential to provide a new degree of precision and delivery speed in radiation therapy treatments for cancer patients. Elekta recently received 510(k) clearance (K121328) from the US Food and Drug Administration (FDA) for Agility, enabling US medical centers to provide these clinical advances to their patients with cancer.

An MLC, a device comprised of numerous, individual tungsten “leaves,” is utilized to shape beams of therapeutic radiation that are delivered from different angles around the patient. Using twice the number of leaves typical of many standard MLCs, Agility precisely shapes delivered radiation to the unique contours of the tumor, while reducing the risk of exposure to healthy tissue.

The new Agility MLC also includes ultrafast leaf movements--twice as fast as other MLCs commonly used in the industry--enabling clinicians to further exploit the most advanced cancer therapies such as stereotactic radiosurgery (SRS), stereotactic radiation therapy (SRT), and volumetric-modulated arc therapy (VMAT). Further, with a new lower radiation leakage design, research has shown Agility can considerably reduce the patient's nontherapeutic radiation exposure as compared to other traditional MLCs.

“Culminating from years of close collaboration with our worldwide clinical partners, we are extremely proud to introduce Agility in the United States,” said Jay Hoey, executive vice president, Elekta North America. “With Agility, not only will treatment times be faster, but more importantly, patients also will benefit from this solution's enhanced targeting capabilities, which are expected to improve treatment outcomes as well as reduce the risk of potential complications. The promise of these critical patient benefits has generated a great deal of interest in the US radiation oncology community, which we predict will result in rapid adoption of this technology.”

Soon after Elekta received CE marking for Agility, permitting sales of the device in Europe, clinicians began reporting significant gains in beam-shaping ability and delivery speed. Shorter treatment times have resulted in increased patient comfort and convenience, as well as improved the ability for caregivers to treat more patients each day.

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67 (46.014785766602): select jos_linkedin.link from jos_linkedin where cat=10

68 (55.789947509766): SELECT fid FROM jos_deeppockets WHERE id=294741632 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294741632 AND published='1' LIMIT 1

69 (45.061111450195): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=211 ORDER BY `ordering`

70 (710.01052856445): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294741632 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (257.96890258789): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294741632 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (682.11555480957): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (899.07646179199): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (61.988830566406): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (42.200088500977): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (46.014785766602): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (285.14862060547): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (50.067901611328): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (43.869018554688): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (!!!!! 1827.9552459717): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (53.882598876953): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (73.19450378418): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294741632 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (66.995620727539): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294741632 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (47.206878662109): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (!!!!! 3520.0119018555): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (119.92454528809): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (97.036361694336): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (39.100646972656): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (92.983245849609): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (33.855438232422): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (39.815902709961): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (39.100646972656): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (120.87821960449): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741632 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741632 AND published='1' LIMIT 1

105 (63.180923461914): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741632 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741632 AND published='1' LIMIT 1

106 (78.916549682617): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294741632 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (65.088272094727): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294741632 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (!!!!! 3324.031829834): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741632 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741632 AND published='1' LIMIT 1

109 (105.14259338379): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741632 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741632 AND published='1' LIMIT 1

110 (74.148178100586): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294741632 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (599.14588928223): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294741632 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (!!!!! 16663.074493408): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (!!!!! 6543.8747406006): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (!!!!! 1835.823059082): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741632 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741632 AND published='1' LIMIT 1

115 (!!!!! 3819.9424743652): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741632 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741632 AND published='1' LIMIT 1

116 (924.82566833496): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741632 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741632 AND published='1' LIMIT 1

117 (308.03680419922): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741632 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741632 AND published='1' LIMIT 1

118 (564.8136138916): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741632 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741632 AND published='1' LIMIT 1

119 (249.86267089844): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741632 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741632 AND published='1' LIMIT 1

120 (209.09309387207): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741632 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741632 AND published='1' LIMIT 1

121 (310.89782714844): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741632 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741632 AND published='1' LIMIT 1

122 (!!!!! 3749.8474121094): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 44577.121734619): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (!!!!! 1110.0769042969): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294741632 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294741632 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (559.09156799316): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (41.007995605469): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (41.961669921875): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (31.948089599609): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (214.0998840332): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (189.06593322754): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (34.093856811523): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (31.948089599609): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (164.03198242188): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (35.04753112793): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (!!!!! 1081.9435119629): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741632 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (959.87319946289): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741632 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (319.00405883789): SELECT name FROM jos_deeppockets WHERE id=211

138 (50.067901611328): SELECT name FROM jos_deeppockets WHERE id=211

139 (924.11041259766): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (664.94941711426): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (!!!!! 3281.831741333): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741632 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741632 AND published='1' LIMIT 1

142 (924.11041259766): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741632 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741632 AND published='1' LIMIT 1

143 (!!!!! 12938.976287842): TRUNCATE TABLE jos_trademed_module

144 (!!!!! 4662.9905700684): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294741632 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (720.97778320312): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294741632 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (!!!!! 6243.9441680908): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741632 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (519.99092102051): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741632 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (!!!!! 4054.069519043): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741632 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741632 AND published='1' LIMIT 1

149 (!!!!! 7910.9668731689): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741632 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741632 AND published='1' LIMIT 1

150 (!!!!! 1629.8294067383): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (106.0962677002): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741632 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741632 AND published='1' LIMIT 1

152 (71.048736572266): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741632 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741632 AND published='1' LIMIT 1

153 (!!!!! 1011.1331939697): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294741632 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294741632 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (56.982040405273): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

155 (!!!!! 1559.0190887451): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

156 (!!!!! 1255.989074707): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (!!!!! 3584.8617553711): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741632 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741632 AND published='1' LIMIT 1

158 (!!!!! 7509.9468231201): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294741632 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294741632 AND published='1' LIMIT 1

159 (608.92105102539): select jos_twitters.link from jos_twitters where cat=10

160 (!!!!! 8311.9869232178): select jos_facebook.link from jos_facebook where cat=10

161 (!!!!! 3616.0945892334): select jos_google_plus.link from jos_google_plus where cat=10

162 (357.86628723145): select jos_linkedin.link from jos_linkedin where cat=10

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