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Radiosurgery, Tumor-Tracking Advancements Reduce Treatment Time for Cancer, Enhance Precision of Treatment

By MedImaging International staff writers
Posted on 06 Mar 2012

New technology expedites radiosurgery for spine, brain, and lung cancer and real-time tumor tracking enhances precision of prostate treatments.

Radiosurgery with fast dose delivery technology can drastically reduce the time it takes to complete treatments for spine, brain, and lung cancer, whereas tumor-tracking technology can enhance the precision of prostate cancer treatments, according to leading radiation oncologists.

The clinicians detailed their findings at the Varian Medical Systems (Palo Alto, CA, USA)-sponsored workshops during the scientific meeting of the Radiosurgery Society (RSS) held in Carlsbad (CA, USA) in February 2012. John B. Fiveash, MD, professor of radiation oncology, and Richard Popple, PhD, associate professor of medical physics at the University of Alabama at Birmingham (UAB; USA), detailed clinical experiences using RapidArc radiosurgery on a TrueBeam STx system developed by Varian.

Drawing on their experience planning and delivering some 435 courses of treatment for prostate, head and neck, brain, spine, lung, liver, and pancreatic cancer, Dr. Fiveash and Dr. Popple described the potential benefits of the high intensity mode on TrueBeam STx, which makes it possible to deliver dose more quickly than conventional dose delivery methods, and may reduce the amount of radiation scatter than can reach surrounding healthy tissues during treatment.

“The TrueBeam STx machine allows radiosurgery to be completed in a dramatically short time frame,” said Dr. Fiveash, who is also the interim associate director for clinical research at the UAB Comprehensive Cancer Center. “In many cases, these procedures can be scheduled to fit into a normal radiotherapy treatment time slot.”

The UAB clinicians also described their experiences using TrueBeam to deliver RapidArc radiosurgery, a fast, accurate strategy to targeting cancer with carefully shaped high-energy beams during one or more continuous rotations of the treatment machine around the patient. “RapidArc Radiosurgery enables us to deliver a highly conformal dose to a tumor, using multiple partial non-coplanar arcs,” Dr. Fiveash said, describing an approach to radiosurgery that increases the number of beam angles used, thereby minimizing the dose to surrounding healthy tissues.

In another Varian-sponsored workshop, Constantine A. Mantz, MD, chief medical officer at 21st Century Oncology (Fort Myers, FL, USA), presented preliminary findings from a prospective phase II study showing that low-risk prostate cancer patients treated with radiosurgery using Calypso real-time tracking technology had favorable health-related quality of life scores and minimal toxicities. The study evaluated 84 patients who received treatment between January 2007 and January 2011. Patients received five treatments, on alternating days, each at 8.0 Gy. Patients completed a quality of life questionnaire before and after treatment. Follow-up data were collected from patients three, six, and nine months, as well as one, two, and three years’ post-treatment.

Dr. Mantz emphasized that real-time tumor tracking is proving to be an important tool for decreasing treatment margins during SBRT for prostate cancer, which is vital in limiting side effects. “Based on 36 months’ worth of follow up data, our prostate cancer trial is showing that real-time tumor tracking with SBRT [stereotactic body radiation therapy, a form of radiosurgery targeting tumors in the body] appears to have clinically significant benefits in decreasing acute toxicity, as well as improving quality of life and biochemical outcomes. The Calypso real-time tracking technology enables us to deliver increased doses of radiation accurately to the tumor and minimize exposure of surrounding healthy tissues. These are the fundamental goals when treating prostate cancer.”

“Radiosurgery is poised to make a big difference in how cancer is treated,” said Tim Guertin, president and CEO of Varian Medical Systems, a major cosponsor of the meeting, in an address he made during one of the general sessions. “As the technology has advanced, radiosurgery utilization has been steadily rising over the last decade because clinicians are seeing--and publishing about--real benefits to patients.”

Varian’s TrueBeam machine and RapidArc Radiosurgery were also the focus of two of the meeting’s scientific sessions. Corey Zankowski, PhD, vice president of product management at Varian, collaborated with Sonia Dieterich, PhD, clinical associate professor and chief of physics at the department of radiation oncology, Stanford University Medical Center (Stanford, CA, USA), to detail the ways in which Varian’s TrueBeam and TrueBeam STx platforms have been optimized for radiosurgical procedures. In a following session, they reviewed the technical and clinical advantages of RapidArc Radiosurgery, summarizing the literature as well as Stanford’s clinical experience using this modality to treat brain, spine, lung, gastrointestinal, and genitourinary cancer.

“The applications, technologies, and methodologies in the field of radiosurgery have been developing rapidly over the last 10 years,” said Kolleen Kennedy, president of Varian’s oncology systems business. “We commend The Radiosurgery Society for its efforts to meet the need for continual learning in this field. The Society put together a stellar and comprehensive program with world-class clinical thought leaders who presented on a wide spectrum of topics over a period of three days. Varian was pleased to be the leading sponsor of this important meeting.”

Related Links:
Varian Medical Systems
University of Alabama at Birmingham
Stanford University Medical Center

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56 (!!!!! 2779.0069580078): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294739633 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

57 (!!!!! 4088.1633758545): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739633 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739633 AND published='1' LIMIT 1

58 (226.02081298828): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739633 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739633 AND published='1' LIMIT 1

59 (!!!!! 6122.8275299072): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739633 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739633 AND published='1' LIMIT 1

60 (828.98139953613): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739633 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739633 AND published='1' LIMIT 1

61 (!!!!! 13635.158538818): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

62 (!!!!! 1343.9655303955): SELECT fid FROM jos_deeppockets WHERE id=294739633 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294739633 AND published='1' LIMIT 1

63 (277.99606323242): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=211 ORDER BY `ordering`

64 (!!!!! 1174.9267578125): select jos_twitters.link from jos_twitters where cat=10

65 (!!!!! 1615.047454834): select jos_facebook.link from jos_facebook where cat=10

66 (!!!!! 1403.0933380127): select jos_google_plus.link from jos_google_plus where cat=10

67 (72.956085205078): select jos_linkedin.link from jos_linkedin where cat=10

68 (731.9450378418): SELECT fid FROM jos_deeppockets WHERE id=294739633 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294739633 AND published='1' LIMIT 1

69 (134.94491577148): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=211 ORDER BY `ordering`

70 (746.01173400879): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294739633 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (!!!!! 1096.9638824463): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294739633 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (61.988830566406): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (!!!!! 1885.1757049561): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (274.8966217041): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (257.01522827148): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (40.054321289062): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (605.82160949707): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (52.928924560547): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (!!!!! 4296.0643768311): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (!!!!! 4058.1226348877): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (!!!!! 4636.0492706299): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (!!!!! 7042.8848266602): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (!!!!! 3885.03074646): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (!!!!! 2089.0235900879): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (!!!!! 3633.0223083496): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (!!!!! 7938.8618469238): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (!!!!! 3535.9859466553): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294739633 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (!!!!! 7931.9477081299): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294739633 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (!!!!! 7924.0798950195): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (!!!!! 1203.0601501465): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (64.13459777832): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (383.85391235352): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (227.92816162109): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (47.922134399414): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (!!!!! 4948.1391906738): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (394.10591125488): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (49.829483032227): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (!!!!! 1430.0346374512): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (50.067901611328): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (32.186508178711): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (241.04118347168): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (!!!!! 4589.0808105469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739633 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739633 AND published='1' LIMIT 1

105 (724.07722473145): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739633 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739633 AND published='1' LIMIT 1

106 (102.04315185547): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294739633 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (981.09245300293): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294739633 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (!!!!! 4626.0356903076): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739633 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739633 AND published='1' LIMIT 1

109 (78.916549682617): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739633 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739633 AND published='1' LIMIT 1

110 (99.897384643555): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294739633 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (!!!!! 1057.1479797363): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294739633 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (!!!!! 1302.95753479): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (742.91229248047): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (!!!!! 1564.0258789062): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739633 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739633 AND published='1' LIMIT 1

115 (72.956085205078): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739633 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739633 AND published='1' LIMIT 1

116 (435.11390686035): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739633 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739633 AND published='1' LIMIT 1

117 (58.889389038086): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739633 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739633 AND published='1' LIMIT 1

118 (630.14030456543): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739633 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739633 AND published='1' LIMIT 1

119 (190.97328186035): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739633 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739633 AND published='1' LIMIT 1

120 (530.00450134277): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739633 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739633 AND published='1' LIMIT 1

121 (223.87504577637): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739633 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739633 AND published='1' LIMIT 1

122 (715.01731872559): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 51002.979278564): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (!!!!! 1530.1704406738): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294739633 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294739633 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (76.055526733398): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (54.836273193359): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (797.98698425293): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (67.949295043945): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (416.99409484863): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (241.04118347168): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (143.05114746094): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (!!!!! 1062.1547698975): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (314.95094299316): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (45.061111450195): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (!!!!! 1121.997833252): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739633 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (501.15585327148): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739633 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (56.028366088867): SELECT name FROM jos_deeppockets WHERE id=211

138 (36.001205444336): SELECT name FROM jos_deeppockets WHERE id=211

139 (737.19024658203): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (686.8839263916): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (524.04403686523): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739633 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739633 AND published='1' LIMIT 1

142 (340.93856811523): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739633 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739633 AND published='1' LIMIT 1

143 (!!!!! 18707.990646362): TRUNCATE TABLE jos_trademed_module

144 (111.81831359863): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294739633 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (62.227249145508): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294739633 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (!!!!! 4065.990447998): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739633 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (157.11784362793): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739633 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (!!!!! 3540.9927368164): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739633 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739633 AND published='1' LIMIT 1

149 (137.0906829834): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739633 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739633 AND published='1' LIMIT 1

150 (!!!!! 1420.9747314453): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (!!!!! 1655.101776123): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739633 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739633 AND published='1' LIMIT 1

152 (108.00361633301): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739633 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739633 AND published='1' LIMIT 1

153 (46.968460083008): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294739633 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294739633 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (46.968460083008): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

155 (36.954879760742): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

156 (46.968460083008): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (204.08630371094): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739633 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739633 AND published='1' LIMIT 1

158 (63.180923461914): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739633 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739633 AND published='1' LIMIT 1

159 (54.121017456055): select jos_twitters.link from jos_twitters where cat=10

160 (33.855438232422): select jos_facebook.link from jos_facebook where cat=10

161 (36.954879760742): select jos_google_plus.link from jos_google_plus where cat=10

162 (41.007995605469): select jos_linkedin.link from jos_linkedin where cat=10

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