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Use of Iodinated Contrast Media Affects Thyroid Function

By MedImaging International staff writers
Posted on 30 Jan 2012

Exposure to iodinated contrast media during imaging procedures is linked to alterations in thyroid function and increased risk of developing hyperthyroidism.

The report’s findings were published in the January 23, 2012, issue of Archives of Internal Medicine, one of the Journal of American Medical Association (JAMA)/Archives journals. “Iodinated contrast media [ICM] are commonly administered pharmaceutical agents,” the authors wrote. ICM are frequently used in scans and imaging procedures such as cardiac catheterization and computed tomography (CT) scans. “Although certain complications of ICM [e.g., contrast-induced nephropathy] have been extensively studied, there has been little examination of the effect of ICM on thyroid function.”

Connie M. Rhee, MD, and colleagues from Brigham and Women’s Hospital, Massachusetts General Hospital, and Harvard Medical School, all Boston (MA, USA)-based organizations, studied data from patients treated between January 1990 and June 2010 who did not have preexisting hyperthyroidism or hypothyroidism. Patients were matched with euthyroid (normal thyroid function) controls, and exposure to iodinated contrast media was evaluated using claims data.

A total of 178 patients with incident hyperthyroidism and 213 patients with incident hypothyroidism were matched to 655 and 779 euthyroid individuals, respectively. The investigators found that iodinated contrast media exposure was linked with incident hyperthyroidism, but no statistically significant association was found with incident hypothyroidism.

A secondary analysis indicated an association between iodinated contrast media exposure and incident overt (clinical; diagnosed based on characteristic clinical features) hypothyrodism and incident overt (clinical) hyperthyroidism.

“In summary, these data support association between ICM exposure and incident hyperthyroidism, incident overt hyperthyroidism and incident overt hypothyroidism,” the authors concluded. “Given the pervasive use of ICM in contemporary practice and the known sequelae of thyroid functional derangements, further studies are needed to confirm and evaluate generalizability of these findings, to establish causality and to explore mechanisms.”

In an accompanying invited commentary, Elizabeth N. Pearce, MD, MSc, from Boston University School of Medicine (MA, USA) wrote that Dr. Rhee and colleagues “describe significant associations between contrast exposure and the development of hyperthyroidism. While no overall association exists between contrast exposure and all forms of hypothyroidism, an association was noted when cases were restricted to those with overt hypothyroidism. These data represent an important contribution to our knowledge about a clinically relevant and understudied area. Rhee et al have demonstrated that a relatively large proportion of individuals who developed iodine-induced thyroid dysfunction were not known to have underlying risk factors. Therefore, patients who may be particularly unable to tolerate thyroid dysfunction, such as those with underlying unstable cardiovascular disease, are also good candidates for monitoring of thyroid function after iodine exposure.”

Related Links:
Brigham and Women’s Hospital
Massachusetts General Hospital
Harvard Medical School

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65 (30.040740966797): select jos_facebook.link from jos_facebook where cat=10

66 (33.855438232422): select jos_google_plus.link from jos_google_plus where cat=10

67 (29.802322387695): select jos_linkedin.link from jos_linkedin where cat=10

68 (112.05673217773): SELECT fid FROM jos_deeppockets WHERE id=294739074 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294739074 AND published='1' LIMIT 1

69 (52.928924560547): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=211 ORDER BY `ordering`

70 (420.09353637695): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294739074 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (262.97569274902): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294739074 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (46.014785766602): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (64.13459777832): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (43.153762817383): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (38.14697265625): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (108.00361633301): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (43.153762817383): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (56.982040405273): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (43.869018554688): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (58.174133300781): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294739074 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (36.001205444336): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294739074 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (39.100646972656): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (65.803527832031): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (52.928924560547): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (41.007995605469): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (41.007995605469): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (46.014785766602): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (39.100646972656): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (44.822692871094): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (33.140182495117): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (79.154968261719): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (124.93133544922): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739074 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739074 AND published='1' LIMIT 1

105 (63.180923461914): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739074 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739074 AND published='1' LIMIT 1

106 (78.201293945312): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294739074 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (73.909759521484): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294739074 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (105.85784912109): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739074 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739074 AND published='1' LIMIT 1

109 (75.101852416992): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739074 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739074 AND published='1' LIMIT 1

110 (69.856643676758): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294739074 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (708.81843566895): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294739074 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (725.03089904785): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (529.05082702637): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (217.19932556152): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739074 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739074 AND published='1' LIMIT 1

115 (72.956085205078): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739074 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739074 AND published='1' LIMIT 1

116 (55.074691772461): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739074 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739074 AND published='1' LIMIT 1

117 (106.0962677002): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739074 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739074 AND published='1' LIMIT 1

118 (51.021575927734): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739074 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739074 AND published='1' LIMIT 1

119 (40.054321289062): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739074 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739074 AND published='1' LIMIT 1

120 (65.088272094727): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739074 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739074 AND published='1' LIMIT 1

121 (51.021575927734): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739074 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739074 AND published='1' LIMIT 1

122 (364.06517028809): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 23538.112640381): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (573.15826416016): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294739074 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294739074 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (56.028366088867): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (36.001205444336): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (92.983245849609): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (32.901763916016): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (102.99682617188): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (52.928924560547): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (36.954879760742): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (31.948089599609): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (31.948089599609): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (29.802322387695): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (580.0724029541): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739074 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (490.90385437012): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739074 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (49.114227294922): SELECT name FROM jos_deeppockets WHERE id=211

138 (31.948089599609): SELECT name FROM jos_deeppockets WHERE id=211

139 (751.97219848633): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (701.904296875): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (77.009201049805): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739074 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739074 AND published='1' LIMIT 1

142 (67.949295043945): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739074 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739074 AND published='1' LIMIT 1

143 (!!!!! 10684.013366699): TRUNCATE TABLE jos_trademed_module

144 (152.8263092041): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294739074 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (68.902969360352): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294739074 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (977.99301147461): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739074 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (66.995620727539): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739074 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (80.108642578125): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739074 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739074 AND published='1' LIMIT 1

149 (65.088272094727): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739074 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739074 AND published='1' LIMIT 1

150 (!!!!! 1429.0809631348): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (66.995620727539): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739074 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739074 AND published='1' LIMIT 1

152 (50.067901611328): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739074 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739074 AND published='1' LIMIT 1

153 (61.988830566406): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294739074 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294739074 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (55.074691772461): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

155 (44.822692871094): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

156 (41.007995605469): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (82.015991210938): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739074 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739074 AND published='1' LIMIT 1

158 (47.922134399414): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739074 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739074 AND published='1' LIMIT 1

159 (51.975250244141): select jos_twitters.link from jos_twitters where cat=10

160 (33.855438232422): select jos_facebook.link from jos_facebook where cat=10

161 (35.04753112793): select jos_google_plus.link from jos_google_plus where cat=10

162 (50.067901611328): select jos_linkedin.link from jos_linkedin where cat=10

163 (307.08312988281): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

164 (!!!!! 1883.0299377441): insert into jos_banners_delta values (14615,'2025-08-19 23:02:57','216.73.216.0','view'),(14202,'2025-08-19 23:02:57','216.73.216.0','view'),(14203,'2025-08-19 23:02:57','216.73.216.0','view')

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