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Up to 70% Reduction in Radiation Dose Achievable for Positron Emission Mammography Imaging

By MedImaging International staff writers
Posted on 20 Sep 2010

Radiation a patient receives from positron emission mammography (PEM) may be reduced by as much as 70% without altering image quality.

The study's findings were presented at the American Association of Physicists in Medicine (AAPM) 52nd annual meeting in Philadelphia (PA, USA) in August 2010 by researchers from the University of Washington (Seattle, USA).

PEM scanners are high-resolution breast PET systems that show the location as well as the metabolic phase of a lesion. More...

The metabolic image helps clinicians to make the optimal cancer care decision by providing an unprecedented ability to differentiate between benign and malignant lesions, what researchers term specificity. PEM is different from X-ray mammography in that it is currently not used as a screening modality, instead is utilized to confirm extent of disease in a patient already diagnosed with a primary breast cancer.

"We have several tools to help us make better patient care choices. Mammography is our primary screening tool. PEM is used in women with known breast cancer in order to plan treatment,” said Wendie Berg, M.D., a breast-imaging radiologist based in Lutherville (MD, USA). "Radiation for treatment of breast cancer uses doses which are roughly 5,000 times higher than a diagnostic PEM study. Minimizing radiation dose is still important for any patient, and we can likely cut the dose of PEM in half, but the benefit to proper treatment exceeds the still low risk from the radiation dose of PEM.”

Dr. Lawrence MacDonald, research assistant professor in the department of radiology at the University of Washington, and his team presented findings of a study to detect lesions with very low doses of radiation using the Naviscan PEM scanner. Early results using phantom images suggest that PEM lesion detection can be reduced down to approximately 3 mCi injected dose of 18FDG or three to four times lower than the dose typically used in clinical practice, while maintaining lesion detectability. These results are the basis of an ongoing clinical trial at Swedish Cancer Institute (Seattle, WA, USA) with the goal of determining the optimized dose levels of FDG required to produce high quality PEM images in patients with breast cancer.

"Naviscan believes that the radiation dose to patients who undergo PEM can be cut at least in half, if not more as suggested by the University of Washington study,” said Judy Kalinyak, M.D., medical director, Naviscan, Inc. "Our site in Japan is already injecting 5 mCi of FDG compared to the 10 mCi in the US and a recently published abstract in the Journal of Nuclear Medicine further validates the reduction in dose down to 5 mCi.”

Results from a recent presentation at the Society of Nuclear Medicine on findings from an U.S. National Institutes of Health (NIH; Bethesda, MD, USA)-sponsored clinical study comparing PEM with breast magnetic resonance imaging (MRI) further demonstrate PEM's clinical appropriateness. This multisite study of hundreds of women with newly diagnosed breast cancer revealed that PEM demonstrated a 6% improvement in specificity at comparably high sensitivity, and also recommended fewer unnecessary biopsies. These results are particularly significant for women who cannot tolerate an MRI exam and require an alternate imaging tool.

The Naviscan PEM scanner is currently installed and available in breast and imaging centers throughout the United States and other parts of the world. The company is the first to obtain U.S. Food and Drug Administration (FDA)-clearance for a high-resolution PET scanner designed to image small body parts and for breast biopsy image guidance.

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University of Washington
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59 (75.817108154297): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731215 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731215 AND published='1' LIMIT 1

60 (136.8522644043): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731215 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731215 AND published='1' LIMIT 1

61 (48.87580871582): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731215 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731215 AND published='1' LIMIT 1

62 (138.99803161621): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

63 (684.97657775879): SELECT fid FROM jos_deeppockets WHERE id=294731215 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294731215 AND published='1' LIMIT 1

64 (468.96934509277): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=211 ORDER BY `ordering`

65 (87.02278137207): select jos_twitters.link from jos_twitters where cat=10

66 (51.975250244141): select jos_facebook.link from jos_facebook where cat=10

67 (46.968460083008): select jos_google_plus.link from jos_google_plus where cat=10

68 (46.014785766602): select jos_linkedin.link from jos_linkedin where cat=10

69 (57.93571472168): SELECT fid FROM jos_deeppockets WHERE id=294731215 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294731215 AND published='1' LIMIT 1

70 (45.061111450195): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=211 ORDER BY `ordering`

71 (267.98248291016): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294731215 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (271.08192443848): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294731215 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

73 (42.200088500977): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

74 (84.161758422852): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (53.167343139648): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (49.114227294922): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (41.007995605469): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (47.922134399414): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (41.961669921875): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (46.014785766602): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (43.153762817383): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (41.007995605469): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (44.822692871094): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (40.054321289062): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (46.014785766602): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (40.054321289062): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (82.015991210938): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294731215 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (50.067901611328): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294731215 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

90 (53.167343139648): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

91 (90.122222900391): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (51.021575927734): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (60.796737670898): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (46.968460083008): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (54.121017456055): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (41.961669921875): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (51.021575927734): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (43.153762817383): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (48.160552978516): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (41.007995605469): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (49.829483032227): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (41.007995605469): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

105 (103.95050048828): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731215 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731215 AND published='1' LIMIT 1

106 (71.048736572266): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731215 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731215 AND published='1' LIMIT 1

107 (79.870223999023): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294731215 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (82.969665527344): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294731215 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

109 (87.02278137207): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731215 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731215 AND published='1' LIMIT 1

110 (67.949295043945): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731215 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731215 AND published='1' LIMIT 1

111 (72.956085205078): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294731215 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (669.00253295898): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294731215 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

113 (549.0779876709): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (310.89782714844): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

115 (77.009201049805): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731215 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731215 AND published='1' LIMIT 1

116 (56.028366088867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731215 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731215 AND published='1' LIMIT 1

117 (60.081481933594): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731215 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731215 AND published='1' LIMIT 1

118 (40.054321289062): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731215 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731215 AND published='1' LIMIT 1

119 (98.943710327148): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731215 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731215 AND published='1' LIMIT 1

120 (39.100646972656): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731215 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731215 AND published='1' LIMIT 1

121 (50.067901611328): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731215 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731215 AND published='1' LIMIT 1

122 (36.001205444336): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731215 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731215 AND published='1' LIMIT 1

123 (241.99485778809): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

124 (!!!!! 24270.057678223): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

125 (532.15026855469): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294731215 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294731215 AND type='deeppockets_item' AND published='1' LIMIT 1

126 (!!!!! 7073.1639862061): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (84.877014160156): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

128 (47.206878662109): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (30.040740966797): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

130 (51.975250244141): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (28.848648071289): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

132 (285.86387634277): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (35.04753112793): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

134 (30.994415283203): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (27.894973754883): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

136 (483.98971557617): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731215 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (313.99726867676): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731215 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

138 (208.85467529297): SELECT name FROM jos_deeppockets WHERE id=211

139 (37.908554077148): SELECT name FROM jos_deeppockets WHERE id=211

140 (653.02848815918): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (478.98292541504): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

142 (69.856643676758): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731215 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731215 AND published='1' LIMIT 1

143 (51.975250244141): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731215 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731215 AND published='1' LIMIT 1

144 (!!!!! 7897.1385955811): TRUNCATE TABLE jos_trademed_module

145 (92.983245849609): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294731215 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (55.789947509766): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294731215 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

147 (823.02093505859): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731215 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (52.928924560547): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731215 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

149 (54.836273193359): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731215 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731215 AND published='1' LIMIT 1

150 (47.206878662109): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731215 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731215 AND published='1' LIMIT 1

151 (!!!!! 1111.0305786133): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

152 (54.121017456055): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731215 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731215 AND published='1' LIMIT 1

153 (41.961669921875): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731215 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731215 AND published='1' LIMIT 1

154 (39.100646972656): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294731215 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294731215 AND type='deeppockets_item' AND published='1' LIMIT 1

155 (411.03363037109): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

156 (37.908554077148): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

157 (31.948089599609): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

158 (66.995620727539): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731215 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731215 AND published='1' LIMIT 1

159 (38.862228393555): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731215 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731215 AND published='1' LIMIT 1

160 (35.04753112793): select jos_twitters.link from jos_twitters where cat=10

161 (30.040740966797): select jos_facebook.link from jos_facebook where cat=10

162 (63.896179199219): select jos_google_plus.link from jos_google_plus where cat=10

163 (36.954879760742): select jos_linkedin.link from jos_linkedin where cat=10

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