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New Method Devised for Detecting High-Risk Cardiovascular Disease

By MedImaging International staff writers
Posted on 09 Sep 2010

Researchers have for the first time developed a way to visualize coronary artery plaques susceptible to rupture using multicolor computed tomography (CT) imaging, a development that should lead to better and earlier diagnosis, and subsequently, treatment of cardiovascular disease.

Ruptures of atherosclerotic plaques are the cause of nearly 70% of heart attacks. High-density lipoproteins (HDL), the "good” cholesterol, are drawn to plaques vulnerable to rupture and remove them from the arterial wall. The scientists, from Mount Sinai School of Medicine (New York, NY, USA), harnessed HDL by encapsulating tiny gold particles within it and injected them into mice. By using an advanced multi-color CT scanner, the researchers were able to see the gold particles as the HDL was targeting macrophages, or the cells that cause inflammation in the arterial wall, therefore illuminating the location of the vulnerable plaques.

"The use of multi-color CT and gold nanoparticles to visualize plaque will revolutionize cardiac imaging,” said the research team leader, Zahi A. Fayad, Ph.D., professor of radiology and medicine and the director of the Translational and Molecular Imaging Institute at Mount Sinai School of Medicine. "The acquisition of this technology and development of this method will help us improve cardiovascular disease diagnosis in our patients, furthering our commitment to translational research. We look forward to continuing our study of this technology in the clinical setting.”

Traditional CT detectors provide a gray image of the artery being examined, and do not provide contrast to differentiate types and density of tissue. In addition to showing the impact of the gold particles, spectral CT can simultaneously differentiate calcium deposits and contrast agents used such as iodine, which is frequently used to identify stenoses, or the narrowing of arteries, informing the severity of atherosclerosis and heart attack risk. Mount Sinai is the first institution in the world to use this scanner, developed by Phillips Medical Systems (Best, The Netherlands), in a preclinical setting.

"There is a significant unmet need for imaging technology that visualizes plaque vulnerable to rupture,” said the lead author of the work, David Cormode, Ph.D., postdoctoral fellow, Translational and Molecular Imaging Institute, Mount Sinai School of Medicine. "The fact that the multicolor CT technique shows the gold particles, iodine and calcifications, provides us with a more complete picture of the nature of the atherosclerotic arteries.”

Multicolor CT technology may also be advantageous in imaging other biologic process and diseases, including cancer, kidney disease, and bowel diseases. The Mount Sinai team plans to continue assessing the new scanner in additional animal studies and in humans.

"Mount Sinai has a decades-long history of making advances in cardiac imaging that have had a significant impact on the field and in patient care,” said Valentin Fuster, M.D., Ph.D., director of Mount Sinai Heart, the Zena and Michael A. Wiener Cardiovascular Institute and the Marie-Josee and Henry R. Kravis Center for Cardiovascular Health, The Mount Sinai Medical Center. "As the first center in the world to pioneer this imaging method, we are leading the charge once more in improving diagnostic tools that lessen the potentially devastating impact of heart disease.”

The study's findings were published in the September 2010 issue of the journal Radiology.

Related Links:
Mount Sinai School of Medicine
Phillips Medical Systems

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63 (46.014785766602): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=211 ORDER BY `ordering`

64 (39.815902709961): select jos_twitters.link from jos_twitters where cat=10

65 (27.894973754883): select jos_facebook.link from jos_facebook where cat=10

66 (30.994415283203): select jos_google_plus.link from jos_google_plus where cat=10

67 (29.087066650391): select jos_linkedin.link from jos_linkedin where cat=10

68 (37.193298339844): SELECT fid FROM jos_deeppockets WHERE id=294731061 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294731061 AND published='1' LIMIT 1

69 (32.901763916016): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=211 ORDER BY `ordering`

70 (329.01763916016): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294731061 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (247.95532226562): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294731061 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (41.007995605469): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (48.160552978516): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (50.067901611328): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (43.869018554688): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294731061 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (30.040740966797): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294731061 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (32.901763916016): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (61.988830566406): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (33.855438232422): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (39.100646972656): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (74.863433837891): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731061 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731061 AND published='1' LIMIT 1

105 (44.107437133789): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731061 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731061 AND published='1' LIMIT 1

106 (54.121017456055): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294731061 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (48.160552978516): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294731061 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (87.976455688477): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731061 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731061 AND published='1' LIMIT 1

109 (53.882598876953): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731061 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731061 AND published='1' LIMIT 1

110 (63.180923461914): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294731061 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (515.93780517578): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294731061 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (535.01129150391): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (357.15103149414): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (92.983245849609): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731061 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731061 AND published='1' LIMIT 1

115 (69.856643676758): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731061 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731061 AND published='1' LIMIT 1

116 (47.922134399414): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731061 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731061 AND published='1' LIMIT 1

117 (36.001205444336): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731061 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731061 AND published='1' LIMIT 1

118 (43.153762817383): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731061 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731061 AND published='1' LIMIT 1

119 (35.04753112793): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731061 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731061 AND published='1' LIMIT 1

120 (41.007995605469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731061 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731061 AND published='1' LIMIT 1

121 (38.14697265625): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731061 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731061 AND published='1' LIMIT 1

122 (249.86267089844): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 18779.993057251): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (545.97854614258): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294731061 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294731061 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 7034.0633392334): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (108.95729064941): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (38.14697265625): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (30.040740966797): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (38.14697265625): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (27.894973754883): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (277.99606323242): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (40.054321289062): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (30.994415283203): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (28.133392333984): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (319.00405883789): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731061 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (267.02880859375): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731061 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (51.975250244141): SELECT name FROM jos_deeppockets WHERE id=211

138 (31.948089599609): SELECT name FROM jos_deeppockets WHERE id=211

139 (616.07360839844): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (442.0280456543): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (111.10305786133): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731061 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731061 AND published='1' LIMIT 1

142 (46.968460083008): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731061 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731061 AND published='1' LIMIT 1

143 (!!!!! 6152.1530151367): TRUNCATE TABLE jos_trademed_module

144 (127.07710266113): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294731061 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (736.95182800293): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294731061 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (569.10514831543): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731061 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (317.09671020508): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731061 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (154.01840209961): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731061 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731061 AND published='1' LIMIT 1

149 (245.09429931641): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731061 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731061 AND published='1' LIMIT 1

150 (!!!!! 1654.8633575439): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (285.14862060547): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731061 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731061 AND published='1' LIMIT 1

152 (173.09188842773): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731061 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731061 AND published='1' LIMIT 1

153 (111.10305786133): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294731061 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294731061 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (!!!!! 3242.015838623): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

155 (80.82389831543): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

156 (234.84230041504): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (100.85105895996): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731061 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731061 AND published='1' LIMIT 1

158 (!!!!! 2590.1794433594): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294731061 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294731061 AND published='1' LIMIT 1

159 (!!!!! 1145.8396911621): select jos_twitters.link from jos_twitters where cat=10

160 (40.054321289062): select jos_facebook.link from jos_facebook where cat=10

161 (41.961669921875): select jos_google_plus.link from jos_google_plus where cat=10

162 (!!!!! 1504.1828155518): select jos_linkedin.link from jos_linkedin where cat=10

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