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CT Scans Detect Differences in Lung Blood-Flow Patterns in Smokers

By MedImaging International staff writers
Posted on 18 May 2010

Using computed tomography (CT) scans to measure blood flow in the lungs of people who smoke may offer a way to identify which smokers are most at risk of emphysema before the disease damages and ultimately destroys areas of the lungs, according to new findings.

The study found that smokers who have very subtle signs of emphysema, but still have normal lung function, have very different blood-flow patterns in their lungs compared to nonsmokers and smokers without signs of emphysema. This difference could be used to identify smokers at increased risk of emphysema and allow for early intervention. The study's findings appear in early April 2010 in the early edition of the journal Proceedings of the [U.S.] National Academy of Sciences (PNAS).

"We have developed a new tool to detect early emphysema-related changes that occur in smokers who are susceptible to the disease,” said lead study author Eric Hoffman, Ph.D., a University of Iowa (UI; Iowa City, USA) professor of radiology, internal medicine, and biomedical engineering. "Our discovery may also help researchers understand the underlying causes of this disease and help distinguish this type of emphysema from other forms of chronic obstructive pulmonary disease. This type of CT scan could even be a tool to test the effectiveness of new therapies by looking at the changes in lung blood flow.”

As many as 24 million people in the United States have chronic obstructive pulmonary disease (COPD)--a group of debilitating lung diseases that includes emphysema--and COPD is the fourth leading cause of death nationwide. Because COPD is a group of different diseases, identifying more effective treatments may hinge on differentiating between these diseases and targeting them separately.

The team utilized multidetector row CT imaging to measure blood-flow patterns in the lungs of 41 study participants--17 non-smokers and 24 smokers. All the participants had normal lung function, but 12 of the smokers had very subtle signs of emphysema. The CT scans revealed that these 12 individuals had the most disrupted patterns of blood flow compared to the other participants.

The study findings also support the theory that abnormal blood flow occurs before emphysema develops. "Although the underlying causes of emphysema are not well understood, smoking increases the risk of developing the disease,” Dr. Hoffman said. "Our study suggests that some smokers have an abnormal response to inflammation in their lungs; instead of sending more blood to the inflamed areas to help repair the damage, blood flow is turned off and the inflamed areas deteriorate.”

The cellular pathway that switches off blood flow is helpful when an area of the lung has become permanently blocked and cannot be rescued. In that case, the lung "optimizes gas exchange” and stops supplying the area with blood. However, lung inflammation caused by smoking can be resolved and resultant damage repaired by increased blood flow, which brings oxygen and helpful cellular components to the site of injury.

This study suggests that the ability to distinguish when to turn off or when to increase blood flow is defective in some individuals--probably due to genetic differences. If this genetic difference is combined with smoking, which increases lung inflammation, that could increase the risk of developing emphysema.

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63 (589.13230895996): SELECT fid FROM jos_deeppockets WHERE id=294729380 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294729380 AND published='1' LIMIT 1

64 (84.877014160156): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=211 ORDER BY `ordering`

65 (47.922134399414): select jos_twitters.link from jos_twitters where cat=10

66 (30.040740966797): select jos_facebook.link from jos_facebook where cat=10

67 (30.040740966797): select jos_google_plus.link from jos_google_plus where cat=10

68 (26.941299438477): select jos_linkedin.link from jos_linkedin where cat=10

69 (30.994415283203): SELECT fid FROM jos_deeppockets WHERE id=294729380 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294729380 AND published='1' LIMIT 1

70 (36.954879760742): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=211 ORDER BY `ordering`

71 (257.01522827148): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294729380 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (200.98686218262): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294729380 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

73 (146.86584472656): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

74 (!!!!! 1816.987991333): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (72.002410888672): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (41.007995605469): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (33.855438232422): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (40.054321289062): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (57.93571472168): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294729380 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (30.040740966797): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294729380 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

90 (32.901763916016): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

91 (!!!!! 2981.1859130859): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (102.04315185547): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (55.789947509766): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (40.054321289062): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (33.140182495117): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

105 (152.8263092041): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294729380 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294729380 AND published='1' LIMIT 1

106 (44.107437133789): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294729380 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294729380 AND published='1' LIMIT 1

107 (70.095062255859): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294729380 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (53.882598876953): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294729380 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

109 (!!!!! 1554.012298584): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294729380 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294729380 AND published='1' LIMIT 1

110 (113.96408081055): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294729380 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294729380 AND published='1' LIMIT 1

111 (65.088272094727): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294729380 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (694.99015808105): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294729380 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

113 (!!!!! 8860.1112365723): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (516.89147949219): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

115 (84.877014160156): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294729380 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294729380 AND published='1' LIMIT 1

116 (72.956085205078): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294729380 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294729380 AND published='1' LIMIT 1

117 (95.129013061523): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294729380 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294729380 AND published='1' LIMIT 1

118 (55.789947509766): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294729380 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294729380 AND published='1' LIMIT 1

119 (72.002410888672): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294729380 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294729380 AND published='1' LIMIT 1

120 (68.902969360352): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294729380 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294729380 AND published='1' LIMIT 1

121 (68.902969360352): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294729380 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294729380 AND published='1' LIMIT 1

122 (56.028366088867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294729380 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294729380 AND published='1' LIMIT 1

123 (391.96014404297): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

124 (!!!!! 28831.958770752): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

125 (617.98095703125): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294729380 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294729380 AND type='deeppockets_item' AND published='1' LIMIT 1

126 (75.101852416992): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (36.954879760742): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

128 (36.001205444336): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (30.040740966797): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

130 (38.862228393555): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (29.087066650391): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

132 (29.087066650391): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (28.133392333984): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

134 (48.160552978516): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (31.948089599609): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

136 (515.93780517578): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294729380 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (377.17819213867): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294729380 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

138 (38.862228393555): SELECT name FROM jos_deeppockets WHERE id=211

139 (30.040740966797): SELECT name FROM jos_deeppockets WHERE id=211

140 (725.98457336426): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (488.9965057373): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

142 (66.995620727539): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294729380 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294729380 AND published='1' LIMIT 1

143 (51.975250244141): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294729380 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294729380 AND published='1' LIMIT 1

144 (!!!!! 10886.907577515): TRUNCATE TABLE jos_trademed_module

145 (249.86267089844): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294729380 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (74.148178100586): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294729380 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

147 (890.01655578613): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294729380 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (55.789947509766): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294729380 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

149 (61.03515625): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294729380 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294729380 AND published='1' LIMIT 1

150 (44.107437133789): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294729380 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294729380 AND published='1' LIMIT 1

151 (!!!!! 1362.0853424072): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

152 (54.121017456055): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294729380 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294729380 AND published='1' LIMIT 1

153 (42.915344238281): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294729380 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294729380 AND published='1' LIMIT 1

154 (39.100646972656): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294729380 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294729380 AND type='deeppockets_item' AND published='1' LIMIT 1

155 (35.04753112793): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

156 (32.186508178711): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

157 (40.054321289062): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

158 (68.902969360352): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294729380 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294729380 AND published='1' LIMIT 1

159 (44.822692871094): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294729380 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294729380 AND published='1' LIMIT 1

160 (36.954879760742): select jos_twitters.link from jos_twitters where cat=10

161 (31.948089599609): select jos_facebook.link from jos_facebook where cat=10

162 (31.948089599609): select jos_google_plus.link from jos_google_plus where cat=10

163 (30.040740966797): select jos_linkedin.link from jos_linkedin where cat=10

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