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Study Identifies Children That Do Not Need CT Scanning after Head Trauma

By MedImaging International staff writers
Posted on 29 Sep 2009

A considerable percentage of children who get computed tomography (CT) scans after seemingly minor head trauma do not need them, and as a result are put at increased risk of cancer due to radiation exposure. More...

After analyzing more than 42,000 children with head trauma, a US research team led by two emergency department physicians has developed guidelines for physicians who care for children with head trauma aimed at reducing those risks.

The study's findings appear in an article published online September 14, 2009, and in an upcoming edition of the journal The Lancet. The collaborative study, conducted by investigators from the University of California (UC) Davis (USA), includes data collected at 25 hospitals from children who were evaluated for the possibility of serious brain injury following trauma to the head. The researchers found that one in five children over the age of two and almost one-quarter of those under two who received CT scans following head trauma did not need them because they were at very low risk of having serious brain injuries. In these low-risk children, the risk of developing cancer due to radiation exposure outweighed the risk of serious brain injury.

"When you have a sample size this large, it is easier to get your hands on the truth," said Dr. Nathan Kuppermann, professor and chair of emergency medicine, professor of pediatrics at UC Davis Children's Hospital and lead author of the study. "We think our investigation provides the best available evidence regarding the use of CT scans in children with head trauma, and it indicates that CT use can be safely reduced by eliminating its application in those children who are at very low risk of serious brain injuries."

As part of the study, Dr. Kuppermann and his colleagues developed a set of rules for identifying low-risk patients who would not need a CT. The "prediction rules" for children under two and for those two and older depend on the presence or absence of various symptoms and circumstances, including the way the injury was sustained, a history of loss of consciousness, neurologic status at the time of evaluation, and clinical evidence of skull fracture for both age groups. The use of CT in patients who do not fall into the low-risk group identified by the prediction rules will depend on other factors, such as the physician's experience, the severity and number of symptoms, and other factors.

The U.S. Centers for Disease Control (Atlanta, GA, USA) estimates that 435,000 children under 14 visit emergency rooms every year to be evaluated for traumatic brain injury (TBI). Not all head trauma results in a TBI. The severity of a brain injury may range from mild, causing brief change in mental status or consciousness, to severe, causing permanent symptoms and irreversible damage.

Studies have long suggested that CT scans were being overused to rule out traumatic brain injuries. However, those studies were considered too small to be sufficiently accurate and not precise enough to be widely applicable to a general population. The sheer size of the current study, and the fact that the investigators created the accurate prediction rules with one large group of children with head trauma and then tested the rules on another large but separate group to demonstrate their validity, allows physicians to have confidence in the results. The researchers emphasized, however, that the rules are not intended to replace clinical judgment.

"We're arming the clinician with the best available evidence so that they can make the best decisions," said Dr. James Holmes, professor of emergency medicine at UC Davis School of Medicine and a co-author of the report. "There certainly are instances when the risks of radiation are worth it, such as in cases of blunt head trauma, which result in changes in neurological status or clinical evidence of skull fractures. However, clinicians need reliable data to help them make those judgment calls when it is not clear whether or not a patient needs a CT. Until now, physicians haven't had data based on large and validated research."

The current study comes on the heels of an article published in late August 2009 by The New England Journal of Medicine (NEJM) that showed that at least 4 million Americans under age 65 are exposed to high doses of radiation each year from medical imaging tests, with CT scans accounting for almost one half of the total radiation dose. Approximately 10% of those get more than the maximum annual exposure allowed for nuclear power plant employees or anyone else who works with radioactive material.

Studies show that exposure to radiation increases the risk of cancer. Radiation exposure to the brain of developing children is of particular concern and must be considered carefully against the risk of traumatic brain injury that could cause permanent damage or death if not identified early. If the new guidelines are applied appropriately, the use of CT scans could be significantly reduced.

The effort was made possible by the Pediatric Emergency Care Applied Research Network (PECARN), which enabled the massive collection of data. Supported by the U.S. Department of Health and Human Services' Emergency Medical Services for Children Program, PECARN is the first U.S.-funded, multi-institutional network for research in pediatric emergency medicine in the nation. The network conducts research into the prevention and management of acute illnesses and injuries in children and youth across the continuum of emergency medicine and healthcare.

"Children with medical and traumatic illnesses usually have good outcomes, but you need a lot of children to assess factors and treatments that predict both good and bad outcomes. By studying large numbers of children, in a variety of settings and from diverse populations, the results will more likely be applicable to the general population. That's the power of PECARN," Dr. Kuppermann said. "Combined, our network of emergency departments around the country evaluates approximately one million children per year."

In order to create the prediction rules, the PECARN investigators studied outcomes in more than 42,000 children with minor initial symptoms and signs of head trauma. CT scans were performed in nearly 15,000 of those patients. Serious brain injuries were diagnosed in 376 children, and 60 children underwent neurosurgery.

Using these data, the researchers developed two prediction rules for identifying mild cases that do not need CT scans. One rule was developed for children under the age of two and another for those two and over. It was important to study children under two separately because they cannot communicate their symptoms or offer information as well as older children, and they are more sensitive to the effects of radiation.

Children under two who fell into the low-risk group showed normal mental status, no scalp swelling, no significant loss of consciousness, no palpable skull fracture, were normal-acting (according to the parent), and had an injury that was sustained in a nonsevere way. Severe accidents, which excluded children from the low-risk group, included motor vehicle crashes in which the patient was ejected, and bicycle accidents involving automobiles, in which the patient was not wearing a helmet. Key indicators for children older than two who were at low-risk for brain injury included normal mental status, no loss of consciousness, no vomiting, no signs of fracture of the base of skull, no severe headache, and they did not sustain the injury in a serious accident.

The researchers then validated these rules by applying them to data from a second population of more than 8,600 children. In more than 99.9% of the cases, the rules accurately predicted children who were not diagnosed with serious brain injuries and were therefore indeed at low risk. The researchers also identified and separated children at intermediate and high risk of serious brain injuries. Those in the high-risk group should receive CT scans, according to the researchers. The PECARN team is now working on refining recommendations for the use of CT scans in those at intermediate risk. Until now, emergency room physicians have relied mostly on instincts when deciding whether the symptoms of a child with head trauma warrant the use of CT.

"Now we have much better evidence to assist with making decisions regarding CT use," Dr. Kuppermann said.

Related Links:
University of California, Davis
Pediatric Emergency Care Applied Research Network

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48 (92.029571533203): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

49 (67.949295043945): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

50 (88.214874267578): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

51 (69.856643676758): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

52 (137.0906829834): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

53 (166.89300537109): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

54 (472.06878662109): SELECT name FROM jos_deeppockets WHERE id=294725587 LIMIT 1

55 (355.00526428223): SELECT name FROM jos_deeppockets_archive WHERE id=294725587 LIMIT 1

56 (88.930130004883): SELECT a.* FROM jos_components AS a WHERE ( a.admin_menu_link = 'option=com_syndicate' OR a.admin_menu_link = 'option=com_syndicate&hidemainmenu=1' ) AND a.option = 'com_syndicate'

57 (102.04315185547): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294725587 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

58 (682.11555480957): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294725587 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

59 (!!!!! 1914.9780273438): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

60 (105.85784912109): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

61 (155.92575073242): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

62 (67.949295043945): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

63 (120.87821960449): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

64 (571.96617126465): SELECT fid FROM jos_deeppockets WHERE id=294725587 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294725587 AND published='1' LIMIT 1

65 (62.942504882812): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=211 ORDER BY `ordering`

66 (73.909759521484): select jos_twitters.link from jos_twitters where cat=10

67 (47.922134399414): select jos_facebook.link from jos_facebook where cat=10

68 (45.061111450195): select jos_google_plus.link from jos_google_plus where cat=10

69 (41.961669921875): select jos_linkedin.link from jos_linkedin where cat=10

70 (83.92333984375): SELECT fid FROM jos_deeppockets WHERE id=294725587 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294725587 AND published='1' LIMIT 1

71 (50.783157348633): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=211 ORDER BY `ordering`

72 (500.91743469238): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294725587 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

73 (303.98368835449): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294725587 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

74 (45.061111450195): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

75 (61.03515625): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (33.855438232422): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (80.82389831543): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (41.007995605469): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (33.140182495117): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

89 (56.982040405273): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294725587 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

90 (34.093856811523): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294725587 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

91 (46.014785766602): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

92 (69.141387939453): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (52.928924560547): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (43.869018554688): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (41.007995605469): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (48.160552978516): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (40.054321289062): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (45.061111450195): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (47.922134399414): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (38.14697265625): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

105 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

106 (92.029571533203): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

107 (64.13459777832): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

108 (50.067901611328): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294725587 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

109 (48.87580871582): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294725587 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

110 (80.82389831543): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

111 (45.7763671875): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

112 (46.014785766602): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294725587 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

113 (606.06002807617): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294725587 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

114 (656.1279296875): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

115 (362.87307739258): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

116 (90.122222900391): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

117 (60.796737670898): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

118 (71.048736572266): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

119 (52.213668823242): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

120 (66.995620727539): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

121 (42.915344238281): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

122 (82.015991210938): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

123 (51.975250244141): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

124 (422.00088500977): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

125 (!!!!! 27184.963226318): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

126 (723.83880615234): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294725587 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294725587 AND type='deeppockets_item' AND published='1' LIMIT 1

127 (!!!!! 11019.945144653): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

128 (108.00361633301): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

129 (83.92333984375): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

130 (46.968460083008): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

131 (97.990036010742): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

132 (41.961669921875): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

133 (421.04721069336): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

134 (66.041946411133): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

135 (47.922134399414): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

136 (39.100646972656): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

137 (640.1538848877): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

138 (550.0316619873): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

139 (58.889389038086): SELECT name FROM jos_deeppockets WHERE id=211

140 (43.869018554688): SELECT name FROM jos_deeppockets WHERE id=211

141 (899.07646179199): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

142 (798.22540283203): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

143 (119.92454528809): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

144 (75.101852416992): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

145 (!!!!! 11074.066162109): TRUNCATE TABLE jos_trademed_module

146 (149.01161193848): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294725587 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

147 (89.883804321289): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294725587 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

148 (642.06123352051): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

149 (77.009201049805): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

150 (96.08268737793): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

151 (71.048736572266): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

152 (!!!!! 1720.9053039551): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

153 (98.943710327148): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

154 (72.002410888672): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

155 (61.988830566406): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294725587 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294725587 AND type='deeppockets_item' AND published='1' LIMIT 1

156 (48.87580871582): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

157 (46.014785766602): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

158 (55.789947509766): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

159 (208.85467529297): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

160 (77.009201049805): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725587 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725587 AND published='1' LIMIT 1

161 (65.088272094727): select jos_twitters.link from jos_twitters where cat=10

162 (36.954879760742): select jos_facebook.link from jos_facebook where cat=10

163 (40.054321289062): select jos_google_plus.link from jos_google_plus where cat=10

164 (41.007995605469): select jos_linkedin.link from jos_linkedin where cat=10

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Novel PET Imaging Approach Offers Never-Before-Seen View of Neuroinflammation

Novel Radiotracer Identifies Biomarker for Triple-Negative Breast Cancer

Innovative PET Imaging Technique to Help Diagnose Neurodegeneration

General/Advanced Imaging

AI-Powered Imaging System Improves Lung Cancer Diagnosis

AI Model Significantly Enhances Low-Dose CT Capabilities

Ultra-Low Dose CT Aids Pneumonia Diagnosis in Immunocompromised Patients

AI Reduces CT Lung Cancer Screening Workload by Almost 80%

Imaging IT

New Google Cloud Medical Imaging Suite Makes Imaging Healthcare Data More Accessible

Global AI in Medical Diagnostics Market to Be Driven by Demand for Image Recognition in Radiology

AI-Based Mammography Triage Software Helps Dramatically Improve Interpretation Process

Artificial Intelligence (AI) Program Accurately Predicts Lung Cancer Risk from CT Images

Industry News

GE HealthCare and NVIDIA Collaboration to Reimagine Diagnostic Imaging

Patient-Specific 3D-Printed Phantoms Transform CT Imaging

Siemens and Sectra Collaborate on Enhancing Radiology Workflows

Bracco Diagnostics and ColoWatch Partner to Expand Availability CRC Screening Tests Using Virtual Colonoscopy

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Study Identifies Children That Do Not Need CT Scanning after Head Trauma

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