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High-Risk Plaque Research Initiative To Identify Individuals at High Risk of Heart Attack or Stroke Two to Three Years before Occurrence

By MedImaging staff writers
Posted on 18 Feb 2008

A High-Risk Plaque Initiative (HRP Initiative) has been developed as a joint research effort to advance the understanding and management of high-risk plaque, which is believed to be the primary underlying cause of heart attacks and strokes.

As part of the research effort, NightHawk Radiology Holdings, Inc.'s (Coeur d'Alene, ID, USA) U.S. Board Certified radiologists will interpret chest computed tomography (CT) scans for approximately 6,000 study participants. Additionally, NightHawk Radiology Services expects its affiliated radiologists will read approximately 1,000 cardiac CT angiography (CTA) scans performed on a subset of participants believed to be at higher risk for a cardiac event. Cardiac CTA (CCTA) is a heart-imaging test that is quickly gaining acceptance for its ability to noninvasively determine whether fatty or calcium deposits (i.e., plaque) have built up in the coronary arteries. The purpose of the interpretation of the CT chest scans by NightHawk's affiliated radiologists is to identify clinically significant cardiac and noncardiac findings where the participant might benefit from its detection and follow-up.

Since there are currently no noninvasive methods of screening, diagnosis, or treatment for high-risk plaque, the HRP Initiative's goal is to provide a roadmap for the development of screening, diagnostic, and therapeutic interventions for high-risk plaque, and promote proper use to patients, providers, and payers.

NightHawk Radiology Services has deployed an independent imaging network system explicitly for the HRP Initiative and it expects to begin evaluating reads in the first quarter of 2008. "We are very excited to be a part of this initiative, which involves high-profile medical institutions, leading pharmaceutical and medical technology companies, and scientists in the fields of cardiology, pathology, and imaging,” said Dr. Paul Berger, chairman and chief executive officer of NightHawk Radiology Services. "Participating in this initiative builds on the opportunities that lie ahead for our new service offerings such as CCTA, which we believe will continue to gain acceptance as the standard noninvasive diagnostic tool.”

NightHawk Radiology provides services to radiology groups and hospitals throughout the United States.

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69 (35.04753112793): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=211 ORDER BY `ordering`

70 (308.03680419922): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=271610000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (222.92137145996): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=271610000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (45.061111450195): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (46.968460083008): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (41.961669921875): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=271610000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (30.040740966797): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=271610000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (32.901763916016): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (46.014785766602): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (32.186508178711): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (69.141387939453): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=271610000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=271610000 AND published='1' LIMIT 1

105 (41.961669921875): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=271610000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=271610000 AND published='1' LIMIT 1

106 (49.114227294922): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=271610000 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (45.061111450195): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=271610000 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (74.863433837891): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=271610000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=271610000 AND published='1' LIMIT 1

109 (45.7763671875): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=271610000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=271610000 AND published='1' LIMIT 1

110 (46.968460083008): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=271610000 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (520.94459533691): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=271610000 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (535.01129150391): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (360.01205444336): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (77.962875366211): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=271610000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=271610000 AND published='1' LIMIT 1

115 (45.061111450195): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=271610000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=271610000 AND published='1' LIMIT 1

116 (58.889389038086): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=271610000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=271610000 AND published='1' LIMIT 1

117 (36.954879760742): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=271610000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=271610000 AND published='1' LIMIT 1

118 (42.915344238281): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=271610000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=271610000 AND published='1' LIMIT 1

119 (36.954879760742): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=271610000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=271610000 AND published='1' LIMIT 1

120 (40.054321289062): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=271610000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=271610000 AND published='1' LIMIT 1

121 (36.954879760742): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=271610000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=271610000 AND published='1' LIMIT 1

122 (258.9225769043): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 19212.961196899): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (524.04403686523): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=271610000 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=271610000 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 7213.1156921387): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (139.95170593262): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (37.908554077148): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (30.040740966797): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (37.908554077148): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (28.848648071289): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (289.9169921875): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (36.001205444336): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (32.901763916016): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (56.982040405273): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (499.01008605957): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=271610000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (339.03121948242): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=271610000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (36.954879760742): SELECT name FROM jos_deeppockets WHERE id=211

138 (29.087066650391): SELECT name FROM jos_deeppockets WHERE id=211

139 (569.10514831543): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (441.07437133789): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (62.942504882812): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=271610000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=271610000 AND published='1' LIMIT 1

142 (49.114227294922): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=271610000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=271610000 AND published='1' LIMIT 1

143 (!!!!! 8688.9266967773): TRUNCATE TABLE jos_trademed_module

144 (82.969665527344): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=271610000 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (49.829483032227): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=271610000 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (782.96661376953): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=271610000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (51.021575927734): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=271610000 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (51.021575927734): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=271610000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=271610000 AND published='1' LIMIT 1

149 (41.007995605469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=271610000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=271610000 AND published='1' LIMIT 1

150 (!!!!! 1092.9107666016): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (54.121017456055): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=271610000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=271610000 AND published='1' LIMIT 1

152 (42.915344238281): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=271610000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=271610000 AND published='1' LIMIT 1

153 (33.140182495117): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=271610000 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=271610000 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (30.040740966797): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

155 (27.894973754883): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

156 (30.040740966797): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (61.988830566406): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=271610000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=271610000 AND published='1' LIMIT 1

158 (44.822692871094): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=271610000 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=271610000 AND published='1' LIMIT 1

159 (35.04753112793): select jos_twitters.link from jos_twitters where cat=10

160 (32.186508178711): select jos_facebook.link from jos_facebook where cat=10

161 (30.994415283203): select jos_google_plus.link from jos_google_plus where cat=10

162 (33.140182495117): select jos_linkedin.link from jos_linkedin where cat=10

163 (236.98806762695): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

164 (925.06408691406): insert into jos_banners_delta values (14615,'2025-08-25 00:10:45','216.73.216.171','view'),(14202,'2025-08-25 00:10:45','216.73.216.171','view'),(14203,'2025-08-25 00:10:45','216.73.216.171','view')

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