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AI Software Uses MRI Scans to Automatically Segment Key Brain Structures for Improved Radiation Therapy Planning

By MedImaging International staff writers
Posted on 04 Sep 2024

Image: A new paradigm in radiation therapy planning aims to improve treatment outcomes for children with brain tumors (Photo courtesy of 123RF)

Advances in radiation therapy have led to significant innovations in the treatment of brain tumors in children, focusing on precision to minimize damage to surrounding healthy brain tissue. However, radiation therapy poses risks, particularly in sensitive areas like the brain, where it can lead to long-term cognitive effects affecting memory, learning, and attention. These side effects can present significant challenges years after treatment. Although current methods can precisely direct radiation to the tumor while sparing critical brain substructures, identifying these areas is crucial. Now, a new artificial intelligence (AI)-based technology aims to revolutionize the planning of brain radiation therapy and enhance treatment outcomes for pediatric brain tumor patients.

Investigators at Children's Hospital Los Angeles (CHLA, Los Angeles, CA, USA) are collaborating with radiation oncology software company Voxel Healthcare (Marina Del Rey, CA, USA) to jointly advance the company’s AI-driven clinical decision support product, ClickBrain RT. While traditional brain tumor radiation treatments aim to minimize exposure to healthy tissues, AI can enhance the precision of these treatments, marking a shift toward improved long-term health outcomes. Voxel’s ClickBrain RT utilizes an AI model that segments the brain into critical substructures affecting cognition, particularly in children. This model is trained on hundreds of MRI images annotated by neuroanatomy experts.

Despite the potential of radiation oncologists to understand complex brain substructures, standardized research on optimal dose tolerances for these specific brain areas is lacking. Such detailed dosage guidelines exist for organs like the kidneys and heart but have not been established for particular brain regions. The collaboration between CHLA and Voxel aims to develop ClickBrain RT not just to automatically segment crucial brain areas but also to provide clinical decision support regarding dosage, considering factors such as the patient's age, chemotherapy regimen, and the type, grade, and location of the tumor. To train the machine learning algorithm, the team will use demographic and neuropsychological data from pediatric brain tumor patients previously treated with radiation, linking specific radiation doses to their long-term impacts. The goal is to advance and validate this technology for widespread use among radiation oncologists, offering hope to children and their families that they can receive effective tumor treatment without experiencing long-term cognitive effects.

“When you cure an 8-year-old patient of their brain tumor, you want to give them the best chance of living the next 70-plus years of their life as healthily and as independently as possible,” said Arthur Olch, PhD, Chief of Physics in the Radiation Oncology Program at CHLA.

“Our main purpose at Voxel Healthcare is to give children a higher chance of reaching their full potential,” said Natasha Leporé, PhD, CHLA brain imaging scientist and co-founder and CTO of Voxel. “We’re excited to work alongside CHLA investigators to achieve this important goal.”

Related Links:
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62 (80.82389831543): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802353 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802353 AND published='1' LIMIT 1

63 (163.07830810547): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

64 (808.0005645752): SELECT fid FROM jos_deeppockets WHERE id=294802353 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294802353 AND published='1' LIMIT 1

65 (72.956085205078): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

66 (82.969665527344): select jos_twitters.link from jos_twitters where cat=10

67 (45.061111450195): select jos_facebook.link from jos_facebook where cat=10

68 (43.869018554688): select jos_google_plus.link from jos_google_plus where cat=10

69 (42.200088500977): select jos_linkedin.link from jos_linkedin where cat=10

70 (61.988830566406): SELECT fid FROM jos_deeppockets WHERE id=294802353 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294802353 AND published='1' LIMIT 1

71 (47.922134399414): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

72 (580.0724029541): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294802353 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

73 (396.0132598877): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294802353 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

74 (66.041946411133): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

75 (84.161758422852): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (44.107437133789): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (48.160552978516): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (79.870223999023): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (44.107437133789): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (38.862228393555): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (42.915344238281): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (38.862228393555): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (66.041946411133): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (41.961669921875): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (46.968460083008): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (38.14697265625): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (41.961669921875): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (40.054321289062): SELECT show_live FROM jos_com_show_setting LIMIT 1

89 (85.115432739258): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294802353 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

90 (48.160552978516): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294802353 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

91 (59.843063354492): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

92 (89.883804321289): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (46.968460083008): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (41.961669921875): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (40.054321289062): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (41.007995605469): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (38.862228393555): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (42.915344238281): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (38.14697265625): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (41.007995605469): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (44.107437133789): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (48.160552978516): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (39.815902709961): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (41.961669921875): SELECT show_live FROM jos_com_show_setting LIMIT 1

105 (41.961669921875): SELECT show_live FROM jos_com_show_setting LIMIT 1

106 (116.10984802246): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802353 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802353 AND published='1' LIMIT 1

107 (76.055526733398): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802353 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802353 AND published='1' LIMIT 1

108 (89.883804321289): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294802353 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

109 (77.962875366211): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294802353 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

110 (113.96408081055): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802353 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802353 AND published='1' LIMIT 1

111 (71.048736572266): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802353 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802353 AND published='1' LIMIT 1

112 (77.962875366211): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294802353 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

113 (844.95544433594): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294802353 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

114 (883.10241699219): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

115 (679.01611328125): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

116 (194.07272338867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802353 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802353 AND published='1' LIMIT 1

117 (87.976455688477): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802353 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802353 AND published='1' LIMIT 1

118 (95.129013061523): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802353 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802353 AND published='1' LIMIT 1

119 (66.995620727539): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802353 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802353 AND published='1' LIMIT 1

120 (89.883804321289): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802353 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802353 AND published='1' LIMIT 1

121 (62.942504882812): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802353 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802353 AND published='1' LIMIT 1

122 (82.015991210938): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802353 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802353 AND published='1' LIMIT 1

123 (63.896179199219): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802353 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802353 AND published='1' LIMIT 1

124 (449.89585876465): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

125 (!!!!! 30945.062637329): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

126 (790.11917114258): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294802353 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294802353 AND type='deeppockets_item' AND published='1' LIMIT 1

127 (!!!!! 10905.027389526): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

128 (125.16975402832): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

129 (82.969665527344): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

130 (46.968460083008): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

131 (77.009201049805): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

132 (46.968460083008): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

133 (511.88468933105): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

134 (123.02398681641): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

135 (57.93571472168): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

136 (43.153762817383): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

137 (634.90867614746): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802353 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

138 (625.1335144043): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802353 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

139 (67.949295043945): SELECT name FROM jos_deeppockets WHERE id=212

140 (41.007995605469): SELECT name FROM jos_deeppockets WHERE id=212

141 (844.95544433594): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

142 (769.13833618164): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

143 (108.00361633301): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802353 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802353 AND published='1' LIMIT 1

144 (73.909759521484): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802353 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802353 AND published='1' LIMIT 1

145 (!!!!! 11097.192764282): TRUNCATE TABLE jos_trademed_module

146 (139.95170593262): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294802353 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

147 (94.890594482422): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294802353 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

148 (663.99574279785): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802353 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

149 (91.075897216797): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802353 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

150 (99.897384643555): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802353 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802353 AND published='1' LIMIT 1

151 (73.909759521484): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802353 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802353 AND published='1' LIMIT 1

152 (!!!!! 1812.9348754883): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

153 (108.00361633301): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802353 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802353 AND published='1' LIMIT 1

154 (76.055526733398): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802353 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802353 AND published='1' LIMIT 1

155 (65.088272094727): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294802353 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294802353 AND type='deeppockets_item' AND published='1' LIMIT 1

156 (54.121017456055): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

157 (46.014785766602): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

158 (56.028366088867): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

159 (106.0962677002): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802353 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802353 AND published='1' LIMIT 1

160 (115.87142944336): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294802353 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294802353 AND published='1' LIMIT 1

161 (66.995620727539): select jos_twitters.link from jos_twitters where cat=10

162 (47.206878662109): select jos_facebook.link from jos_facebook where cat=10

163 (43.153762817383): select jos_google_plus.link from jos_google_plus where cat=10

164 (41.961669921875): select jos_linkedin.link from jos_linkedin where cat=10

165 (421.04721069336): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

166 (!!!!! 1403.0933380127): insert into jos_banners_delta values (14615,'2025-08-01 09:20:29','216.73.216.8','view'),(14202,'2025-08-01 09:20:29','216.73.216.8','view'),(14203,'2025-08-01 09:20:29','216.73.216.8','view')

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