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Diamond Dust Could Offer New Contrast Agent Option for Future MRI Scans

By MedImaging International staff writers
Posted on 29 Apr 2024

Image: Diamond dust offers a potential alternative to the widely used contrast agent gadolinium in MRI (Photo courtesy of Max Planck Institute)

Gadolinium, a heavy metal used for over three decades as a contrast agent in medical imaging, enhances the clarity of MRI scans by highlighting affected areas. Despite its utility, gadolinium not only accumulates in targeted tumor tissues but also disperses into surrounding healthy tissues, where it can remain for months to years, particularly in the brain and kidneys. The long-term impacts of this retention are still unclear, and gadolinium is known to cause several side effects. Consequently, the medical field has long been in search of a safer alternative. Now, an unexpected discovery made in a laboratory suggests that diamond dust, a carbon-based material, might serve as a viable, more tolerable substitute for gadolinium.

This breakthrough was achieved at the Max Planck Institute for Intelligent Systems (Stuttgart, Germany), where researchers initially used nanometer-sized diamond particles for an entirely different experimental purpose. To their surprise, these diamond particles exhibited unexpected brightness in an MRI experiment, shining even more brightly than the actual contrast agent, gadolinium. The experiment involved encapsulating 3 to 5-nanometer diamond particles in tiny drug-delivery capsules made of gelatin that were designed to burst upon heating, leveraging diamond dust's high heat capacity to trigger this reaction. Initially, the researchers included gadolinium to monitor the location of the diamond particles, intending to see if the diamond-enhanced capsules would heat more efficiently. However, they encountered issues with gadolinium leakage from the gelatin, similar to how it would leak out of the bloodstream into patient tissues during clinical use.

Upon deciding to proceed without gadolinium, they observed that the capsules still appeared surprisingly bright in the MRI images, indicating that the diamond dust could have better signal-enhancing properties than gadolinium. They found that, unlike gadolinium which diffuses everywhere, the diamond nanoparticles remained in the blood vessels, did not leak out, and later shone brightly in the MRI, similar to how they had in the gelatin capsules. Given these promising results, the researchers are optimistic about the potential of diamond dust in MRI applications. If further studies confirm its safety and efficacy, diamond dust could emerge as a groundbreaking contrast agent in future MRI procedures, offering a safer alternative to gadolinium.

“Why the diamond dust shines bright in our MRI still remains a mystery to us,” said Dr. Jelena Lazovic Zinnanti, a research scientist, who heads the Central Scientific Facility Medical Systems at MPI-IS. “I think the tiny particles have carbons that are slightly paramagnetic. The particles may have a defect in their crystal lattice, making them slightly magnetic. That’s why they behave like a T1 contrast agent such as gadolinium. Additionally, we don’t know whether diamond dust could potentially be toxic, something that needs to be carefully examined in the future.”

Related Links:
Max Planck Institute for Intelligent Systems

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58 (!!!!! 3473.0434417725): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294801009 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294801009 AND published='1' LIMIT 1

59 (!!!!! 5321.0258483887): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294801009 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294801009 AND published='1' LIMIT 1

60 (267.02880859375): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294801009 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294801009 AND published='1' LIMIT 1

61 (!!!!! 9519.100189209): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

62 (!!!!! 3173.1128692627): SELECT fid FROM jos_deeppockets WHERE id=294801009 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294801009 AND published='1' LIMIT 1

63 (559.80682373047): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

64 (557.18421936035): select jos_twitters.link from jos_twitters where cat=10

65 (199.0795135498): select jos_facebook.link from jos_facebook where cat=10

66 (!!!!! 1852.0355224609): select jos_google_plus.link from jos_google_plus where cat=10

67 (383.85391235352): select jos_linkedin.link from jos_linkedin where cat=10

68 (314.95094299316): SELECT fid FROM jos_deeppockets WHERE id=294801009 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294801009 AND published='1' LIMIT 1

69 (!!!!! 3484.0106964111): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

70 (861.88316345215): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294801009 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (383.85391235352): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294801009 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (!!!!! 1891.1361694336): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (!!!!! 2125.9784698486): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (365.01884460449): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (52.928924560547): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (40.054321289062): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (382.90023803711): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (61.988830566406): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (43.869018554688): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (39.100646972656): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (!!!!! 1657.9627990723): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (61.988830566406): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (46.014785766602): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (41.961669921875): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (344.99168395996): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294801009 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (47.922134399414): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294801009 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (47.922134399414): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (!!!!! 2636.9094848633): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (59.127807617188): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (144.95849609375): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (139.95170593262): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (54.836273193359): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (38.14697265625): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (233.88862609863): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (46.014785766602): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (797.03330993652): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (192.16537475586): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (262.02201843262): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (41.007995605469): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (38.14697265625): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (!!!!! 1364.9463653564): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294801009 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294801009 AND published='1' LIMIT 1

105 (108.95729064941): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294801009 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294801009 AND published='1' LIMIT 1

106 (126.12342834473): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294801009 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (627.04086303711): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294801009 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (!!!!! 4257.9174041748): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294801009 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294801009 AND published='1' LIMIT 1

109 (110.14938354492): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294801009 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294801009 AND published='1' LIMIT 1

110 (234.12704467773): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294801009 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (!!!!! 3513.8130187988): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294801009 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (!!!!! 4642.0097351074): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (!!!!! 5556.8218231201): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (!!!!! 2120.0180053711): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294801009 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294801009 AND published='1' LIMIT 1

115 (339.98489379883): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294801009 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294801009 AND published='1' LIMIT 1

116 (620.12672424316): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294801009 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294801009 AND published='1' LIMIT 1

117 (142.09747314453): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294801009 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294801009 AND published='1' LIMIT 1

118 (86.069107055664): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294801009 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294801009 AND published='1' LIMIT 1

119 (!!!!! 1043.0812835693): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294801009 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294801009 AND published='1' LIMIT 1

120 (101.80473327637): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294801009 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294801009 AND published='1' LIMIT 1

121 (63.896179199219): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294801009 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294801009 AND published='1' LIMIT 1

122 (326.87187194824): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 58676.00440979): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (809.1926574707): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294801009 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294801009 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 28409.004211426): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (68.902969360352): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (771.99935913086): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (164.98565673828): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (481.12869262695): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (724.79248046875): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (!!!!! 1121.0441589355): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (59.127807617188): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (410.07995605469): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (458.0020904541): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (!!!!! 1976.0131835938): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294801009 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (586.03286743164): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294801009 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (!!!!! 1013.9942169189): SELECT name FROM jos_deeppockets WHERE id=212

138 (64.849853515625): SELECT name FROM jos_deeppockets WHERE id=212

139 (!!!!! 3921.9856262207): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (!!!!! 3099.9183654785): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (!!!!! 6187.915802002): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294801009 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294801009 AND published='1' LIMIT 1

142 (!!!!! 1036.1671447754): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294801009 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294801009 AND published='1' LIMIT 1

143 (!!!!! 10562.896728516): TRUNCATE TABLE jos_trademed_module

144 (!!!!! 6820.9171295166): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294801009 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (!!!!! 7919.0731048584): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294801009 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (!!!!! 2285.9573364258): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294801009 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (!!!!! 1391.1724090576): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294801009 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (!!!!! 1644.8497772217): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294801009 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294801009 AND published='1' LIMIT 1

149 (!!!!! 1135.8261108398): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294801009 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294801009 AND published='1' LIMIT 1

150 (!!!!! 3695.9648132324): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (!!!!! 2451.8966674805): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294801009 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294801009 AND published='1' LIMIT 1

152 (!!!!! 1287.9371643066): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294801009 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294801009 AND published='1' LIMIT 1

153 (!!!!! 3456.1157226562): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294801009 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294801009 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (!!!!! 1151.0848999023): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

155 (73.19450378418): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

156 (!!!!! 1029.0145874023): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (!!!!! 1168.0126190186): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294801009 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294801009 AND published='1' LIMIT 1

158 (337.12387084961): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294801009 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294801009 AND published='1' LIMIT 1

159 (!!!!! 4422.9030609131): select jos_twitters.link from jos_twitters where cat=10

160 (339.98489379883): select jos_facebook.link from jos_facebook where cat=10

161 (342.13066101074): select jos_google_plus.link from jos_google_plus where cat=10

162 (46.968460083008): select jos_linkedin.link from jos_linkedin where cat=10

163 (!!!!! 1443.8629150391): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

164 (!!!!! 2009.1533660889): insert into jos_banners_delta values (14615,'2025-08-02 02:59:08','216.73.216.210','view'),(14202,'2025-08-02 02:59:08','216.73.216.210','view'),(14203,'2025-08-02 02:59:08','216.73.216.210','view')

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