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CADx System Combines AI with Low-Cost MRI Scans to Speed up Prostate Cancer Detection

By MedImaging International staff writers
Posted on 29 Mar 2023

Image: New AI tool can safely delay, as well as inexpensively and accurately monitor prostate cancer treatment (Photo courtesy of Bot Image)

The current protocol for treating prostate cancer involves a number of uncomfortable and unreliable procedures. One example is the PSA test, which measures the level of prostate-specific antigen (PSA) in the blood and can sometimes indicate the presence of prostate cancer. However, this test is not conclusive and often leads to additional testing such as MRI to identify any abnormalities in the prostate. The development of new blood, urine or tissue tests for prostate cancer could be very promising but such tests do not reveal the location or extent of the cancer, which is something that imaging with artificial intelligence (AI) can do.

Similarly, digital rectal exams (DREs) have been found to be just slightly over 50% accurate due to the significant number of prostate cancers located in the anterior aspect of the gland, which is far from the rectum and cannot be felt. In addition, while biopsies can confirm the presence of cancer, their random or targeted sampling often miss cancerous lesions. Biopsies are also costly, carry a risk of infection, and can lead to false positives. Therefore, biopsies are not an effective screening method for prostate cancer but can confirm a diagnosis if used in conjunction with imaging guidance. Now, a powerful computer-aided diagnosis (CADx) software device is poised to change the standard of care for prostate cancer screening, detection and diagnosis by avoiding the expensive pitfalls of current prostate cancer pathways.

The ProstatID AI software from Bot Image, Inc. (Omaha, NE, USA) is not only intended for cancer detection and diagnosis but also for prostate cancer screening using MRI and a non-invasive/non-contrast "short-form" of MRI sequences known as bi-parametric MRI (bpMRI). bpMRI eliminates the need for expensive, time-consuming contrast agents that can damage the kidneys, thereby facilitating a low cost and easily accessible MRI. Bot Image's Prostate AI has enormous implications for men's health and healthcare cost savings, as it is a highly accurate tool for active surveillance. This means that periodic low-cost MRI scans supplemented with the AI interpretation of ProstatID can be conducted, resulting in significant savings.

In clinical trials conducted by Bot Image, the algorithm performed with 93.6% accuracy when used on its own (with area under the sensitivity-specificity curve). Additionally, physician performance was considerably enhanced. In comparison, no other screening method comes close to matching ProstatID's level of sensitivity, specificity, and ability to locate and determine the extent of cancer. ProstatID has been developed using thousands of proprietary MR image sets, radiologist interpretations, segmented prostate gland image sets, pathology laboratory results, correlation data, and initial AI interpretations to aid in the early diagnosis of prostate cancer. Bot Image has received FDA-clearance for its ProstatID AI software for cancer detection and diagnosis, as well as for prostate cancer screening using MRI and bpMRI.

Related Links:
Bot Image, Inc.

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68 (82.969665527344): SELECT fid FROM jos_deeppockets WHERE id=294796682 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294796682 AND published='1' LIMIT 1

69 (45.061111450195): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

70 (324.01084899902): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294796682 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (391.00646972656): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294796682 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (64.13459777832): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (49.114227294922): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (26.226043701172): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (24.795532226562): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (24.795532226562): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (33.855438232422): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (!!!!! 4219.0551757812): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294796682 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (83.92333984375): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294796682 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (41.961669921875): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (!!!!! 3813.9820098877): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (118.01719665527): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (38.14697265625): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (103.95050048828): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (32.186508178711): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (59.843063354492): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (53.882598876953): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (111.10305786133): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796682 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796682 AND published='1' LIMIT 1

105 (63.180923461914): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796682 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796682 AND published='1' LIMIT 1

106 (99.897384643555): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294796682 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (51.975250244141): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294796682 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (82.015991210938): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796682 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796682 AND published='1' LIMIT 1

109 (44.107437133789): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796682 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796682 AND published='1' LIMIT 1

110 (87.976455688477): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294796682 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (509.97734069824): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294796682 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (714.06364440918): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (476.83715820312): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (153.0647277832): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796682 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796682 AND published='1' LIMIT 1

115 (111.10305786133): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796682 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796682 AND published='1' LIMIT 1

116 (91.791152954102): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796682 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796682 AND published='1' LIMIT 1

117 (58.889389038086): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796682 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796682 AND published='1' LIMIT 1

118 (109.19570922852): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796682 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796682 AND published='1' LIMIT 1

119 (61.03515625): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796682 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796682 AND published='1' LIMIT 1

120 (384.09233093262): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

121 (!!!!! 45078.992843628): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

122 (141.85905456543): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796682 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796682 AND published='1' LIMIT 1

123 (66.995620727539): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796682 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796682 AND published='1' LIMIT 1

124 (617.02728271484): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294796682 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294796682 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 582605.83877563): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (!!!!! 984062.19482422): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (92.983245849609): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

128 (43.869018554688): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

129 (41.961669921875): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

130 (52.213668823242): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

131 (45.061111450195): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

132 (36.954879760742): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

133 (!!!!! 7646.0838317871): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796682 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

134 (398.87428283691): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796682 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

135 (184.05914306641): SELECT name FROM jos_deeppockets WHERE id=212

136 (48.87580871582): SELECT name FROM jos_deeppockets WHERE id=212

137 (497.10273742676): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

138 (484.94338989258): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

139 (127.07710266113): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796682 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796682 AND published='1' LIMIT 1

140 (52.928924560547): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796682 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796682 AND published='1' LIMIT 1

141 (!!!!! 5233.0493927002): TRUNCATE TABLE jos_trademed_module

142 (!!!!! 1927.8526306152): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294796682 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

143 (108.95729064941): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294796682 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

144 (518.0835723877): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796682 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

145 (72.956085205078): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796682 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

146 (57.93571472168): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796682 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796682 AND published='1' LIMIT 1

147 (72.956085205078): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796682 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796682 AND published='1' LIMIT 1

148 (!!!!! 1472.9499816895): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

149 (119.20928955078): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796682 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796682 AND published='1' LIMIT 1

150 (62.227249145508): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796682 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796682 AND published='1' LIMIT 1

151 (77.962875366211): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294796682 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294796682 AND type='deeppockets_item' AND published='1' LIMIT 1

152 (657.08160400391): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

153 (!!!!! 2068.9964294434): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

154 (44.107437133789): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

155 (!!!!! 3442.0490264893): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796682 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796682 AND published='1' LIMIT 1

156 (80.108642578125): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796682 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796682 AND published='1' LIMIT 1

157 (55.074691772461): select jos_twitters.link from jos_twitters where cat=10

158 (29.087066650391): select jos_facebook.link from jos_facebook where cat=10

159 (30.040740966797): select jos_google_plus.link from jos_google_plus where cat=10

160 (26.941299438477): select jos_linkedin.link from jos_linkedin where cat=10

161 (342.84591674805): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

162 (!!!!! 5640.983581543): insert into jos_banners_delta values (14615,'2025-04-30 08:56:49','3.148.241.210','view'),(14202,'2025-04-30 08:56:49','3.148.241.210','view'),(14203,'2025-04-30 08:56:49','3.148.241.210','view')

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