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First of Its Kind AI Technology Analyzes Fast-Growing Brain Tumors on MRI

By MedImaging International staff writers
Posted on 12 Oct 2022

Image: Neosoma HGG is the first AI-based neuro-oncology software to receive (FDA) 510(k) clearance (Photo courtesy of Neosoma)

High-Grade Gliomas, which includes Glioblastoma, are the most common, and most challenging, malignant primary brain cancers. In clinical practice, the brain MRI is the physician’s best tool to evaluate the details and changes in a brain tumor. However, even for the most experienced physicians this presents considerable challenges, which can have a direct impact on clinical care. Now, an advanced AI-based technology produces precise and accurate brain tumor analysis on brain MRIs, providing physicians with critical insights to help them deliver optimal treatment.

Neosoma HGG (High-Grade Glioma) from Neosoma, Inc. (Groton, MA, USA) is the first technology of its kind to support neuro-oncology clinicians in improving treatment of brain cancers. Neosoma HGG conducts detailed tumor segmentation, volumetric measurements, generates imaging for 3D geometric analysis and longitudinally tracks patients with high-grade glioma brain tumors. These features will help physicians to better plan procedures, assess post-procedural results, guide chemo and immunotherapy treatments and support an improved patient experience. Neosoma HGG is combined with the proprietary Neosoma Clinical Management Software Platform, allowing the multi-disciplinary physician team more effectively centralize clinical data, plan and track patient care, and significantly increase efficiency.

The Neosoma HGG AI-based neuro-oncology software device has received U.S. Food and Drug Administration (FDA) 510(k) clearance. Performance testing results, submitted to the FDA demonstrated that Neosoma HGG’s outputs exceeded that of individual neuro-radiology experts. When compared to a consensus of neuroradiologists, Neosoma HGG achieved an excellent 95.5% accuracy in measuring tumor volumes at multiple timepoints of patient care.

“Clinicians commonly debate the results of brain MRIs and whether the brain tumor is stable, responding to treatment, or progressing. Neosoma HGG will give us the objectivity needed to make our decisions easier and more accurate,” commented Isabelle M. Germano, MD, MBA, FACS, Professor of Neurosurgery and Director of the Comprehensive Brain Tumor Program at The Mount Sinai Medical Center.

“Neosoma HGG will give us a novel tool allowing for comprehensive longitudinal monitoring and understanding of brain tumors, assist in our decision making, and will be a valuable part of our clinical practice. I look forward to using this new and important technology,” stated Roger Stupp, M.D., Chief of Neuro-oncology and Co-director of the Northwestern Medicine Malnati Brain Tumor Institute and Professor of Neurological Surgery, Neurology and Medicine at Northwestern University.

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68 (255.10787963867): SELECT fid FROM jos_deeppockets WHERE id=294794927 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294794927 AND published='1' LIMIT 1

69 (45.061111450195): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

70 (389.09912109375): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294794927 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (!!!!! 1857.9959869385): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294794927 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (!!!!! 1679.1820526123): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (!!!!! 1683.9504241943): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (327.82554626465): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (55.789947509766): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (39.100646972656): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (216.96090698242): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (61.988830566406): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (44.107437133789): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (325.91819763184): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (190.01960754395): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (43.153762817383): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (448.94218444824): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (192.88063049316): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (43.869018554688): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (324.01084899902): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (!!!!! 1103.8780212402): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294794927 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (51.021575927734): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294794927 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (49.114227294922): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (!!!!! 1114.1300201416): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (49.829483032227): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (54.836273193359): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (99.897384643555): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (39.815902709961): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (33.140182495117): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (34.809112548828): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (33.855438232422): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (33.140182495117): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (106.0962677002): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794927 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794927 AND published='1' LIMIT 1

105 (62.942504882812): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794927 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794927 AND published='1' LIMIT 1

106 (86.069107055664): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294794927 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (71.048736572266): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294794927 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (398.15902709961): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794927 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794927 AND published='1' LIMIT 1

109 (!!!!! 2122.8790283203): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794927 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794927 AND published='1' LIMIT 1

110 (72.956085205078): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294794927 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (622.98774719238): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294794927 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (755.07164001465): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (545.02487182617): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (124.93133544922): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794927 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794927 AND published='1' LIMIT 1

115 (63.896179199219): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794927 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794927 AND published='1' LIMIT 1

116 (72.002410888672): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794927 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794927 AND published='1' LIMIT 1

117 (54.836273193359): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794927 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794927 AND published='1' LIMIT 1

118 (60.081481933594): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794927 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794927 AND published='1' LIMIT 1

119 (51.021575927734): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794927 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794927 AND published='1' LIMIT 1

120 (255.10787963867): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

121 (!!!!! 52646.160125732): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

122 (!!!!! 3915.0714874268): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794927 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794927 AND published='1' LIMIT 1

123 (80.108642578125): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794927 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794927 AND published='1' LIMIT 1

124 (492.81120300293): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294794927 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294794927 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 604994.05860901): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (!!!!! 559656.14318848): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (69.856643676758): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

128 (39.100646972656): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

129 (50.067901611328): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

130 (30.040740966797): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

131 (44.107437133789): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

132 (32.901763916016): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

133 (664.94941711426): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794927 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

134 (478.02925109863): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794927 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

135 (89.883804321289): SELECT name FROM jos_deeppockets WHERE id=212

136 (51.021575927734): SELECT name FROM jos_deeppockets WHERE id=212

137 (606.06002807617): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

138 (523.09036254883): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

139 (89.168548583984): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794927 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794927 AND published='1' LIMIT 1

140 (56.982040405273): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794927 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794927 AND published='1' LIMIT 1

141 (!!!!! 7890.9397125244): TRUNCATE TABLE jos_trademed_module

142 (83.92333984375): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294794927 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

143 (56.028366088867): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294794927 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

144 (772.95303344727): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794927 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

145 (73.909759521484): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794927 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

146 (65.088272094727): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794927 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794927 AND published='1' LIMIT 1

147 (56.028366088867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794927 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794927 AND published='1' LIMIT 1

148 (!!!!! 1152.9922485352): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

149 (68.187713623047): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794927 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794927 AND published='1' LIMIT 1

150 (51.021575927734): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794927 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794927 AND published='1' LIMIT 1

151 (42.200088500977): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294794927 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294794927 AND type='deeppockets_item' AND published='1' LIMIT 1

152 (35.04753112793): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

153 (31.948089599609): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

154 (34.093856811523): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

155 (94.175338745117): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794927 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794927 AND published='1' LIMIT 1

156 (51.021575927734): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794927 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794927 AND published='1' LIMIT 1

157 (34.809112548828): select jos_twitters.link from jos_twitters where cat=10

158 (31.948089599609): select jos_facebook.link from jos_facebook where cat=10

159 (30.994415283203): select jos_google_plus.link from jos_google_plus where cat=10

160 (31.232833862305): select jos_linkedin.link from jos_linkedin where cat=10

161 (266.07513427734): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

162 (998.02017211914): insert into jos_banners_delta values (14615,'2025-04-30 14:33:08','3.139.237.218','view'),(14202,'2025-04-30 14:33:08','3.139.237.218','view'),(14203,'2025-04-30 14:33:08','3.139.237.218','view')

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