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AI Could Improve Diagnostic Accuracy of Breast DCE-MRI
By MedImaging International staff writers Posted on 10 Oct 2022
Image: Breast MRI meets AI (Photo courtesy of Pexels)
Early detection is key to improving breast cancer outcomes. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has a high sensitivity in detecting breast cancer and is sometimes used for women at higher risk of breast cancer but often leads to unnecessary biopsies and patient workup. Now, a new study has demonstrated that a deep learning (DL) system could improve the diagnostic accuracy of DCE-MRI of breast tissue for detecting breast cancer,
For the study, researchers at the New York University Grossman School of Medicine (New York City, NY, USA) used a DL system to improve the overall accuracy of breast cancer diagnosis and personalize management of patients undergoing DCE-MRI. On the internal test set (n = 3936 exams), the system achieved an area under the receiver operating characteristic curve (AUROC) of 0.92 (95% CI: 0.92 to 0.93). In a retrospective reader study, there was no statistically significant difference (P = 0.19) between five board-certified breast radiologists and the DL system (mean ΔAUROC, +0.04 in favor of the DL system). Radiologists’ performance improved when their predictions were averaged with DL’s predictions [mean ΔAUPRC (area under the precision-recall curve), +0.07].
Additionally, the researchers demonstrated the generalizability of the DL system using multiple datasets from Poland and the U.S. An additional reader study on a Polish dataset showed that the DL system was as robust to distribution shift as radiologists. In subgroup analysis, the researchers observed consistent results across different cancer subtypes and patient demographics. Using decision curve analysis, the researchers showed that the DL system can reduce unnecessary biopsies in the range of clinically relevant risk thresholds. This would lead to avoiding biopsies yielding benign results in up to 20% of all patients with BI-RADS category 4 lesions. Last, the researchers performed an error analysis, investigating situations where DL predictions were mostly incorrect. This exploratory work creates a foundation for deployment and prospective analysis of DL-based models for breast MRI.
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AND id != 294743306
AND id != 294743307
AND id != 294743308
AND id != 294743309
AND id != 294743310
AND metakey != 'aacc'
ORDER BY `ordering`90
(49.829483032227): SELECT show_live FROM jos_com_show_setting LIMIT 191
(30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 192
(27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 193
(28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 194
(34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 195
(28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 196
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 197
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 198
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 199
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1100
(27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1101
(27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1102
(26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1103
(27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1104
(65.088272094727): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794883 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794883 AND published='1'
LIMIT 1105
(41.007995605469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794883 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794883 AND published='1'
LIMIT 1106
(52.213668823242): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.cat=10
AND dp.id=294794883
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1107
(45.061111450195): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.cat=10
AND dp.id=294794883
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1108
(77.009201049805): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794883 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794883 AND published='1'
LIMIT 1109
(46.014785766602): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794883 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794883 AND published='1'
LIMIT 1110
(46.014785766602): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.id=294794883
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1111
(522.85194396973): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.id=294794883
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1112
(730.99136352539): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp
LEFT JOIN jos_experts as ex
ON ex.id = dp.author
LEFT JOIN jos_deeppockets as dp2
ON dp2.id = dp.fid
WHERE dp.author != 0
AND dp.cat = 10
AND dp.published = 1
AND (
(dp.fid = 294743300)
OR (dp.fid = 294743301)
OR (dp.fid = 294743302)
OR (dp.fid = 294743303)
OR (dp.fid = 294743304)
OR (dp.fid = 294743305)
OR (dp.fid = 294743306)
OR (dp.fid = 294743307)
OR (dp.fid = 294743308)
OR (dp.fid = 294743309)
OR (dp.fid = 294743310)
)
ORDER BY RAND()
LIMIT 1113
(442.9817199707): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp
LEFT JOIN jos_experts as ex
ON ex.id = dp.author
LEFT JOIN jos_deeppockets as dp2
ON dp2.id = dp.fid
WHERE dp.author != 0
AND dp.cat = 10
AND dp.published = 1
AND (
(dp.fid = 294743300)
OR (dp.fid = 294743301)
OR (dp.fid = 294743302)
OR (dp.fid = 294743303)
OR (dp.fid = 294743304)
OR (dp.fid = 294743305)
OR (dp.fid = 294743306)
OR (dp.fid = 294743307)
OR (dp.fid = 294743308)
OR (dp.fid = 294743309)
OR (dp.fid = 294743310)
)
ORDER BY RAND()
LIMIT 1114
(108.95729064941): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794883 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794883 AND published='1'
LIMIT 1115
(160.93254089355): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794883 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794883 AND published='1'
LIMIT 1116
(64.13459777832): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794883 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794883 AND published='1'
LIMIT 1117
(56.982040405273): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794883 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794883 AND published='1'
LIMIT 1118
(72.956085205078): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794883 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794883 AND published='1'
LIMIT 1119
(50.067901611328): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794883 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794883 AND published='1'
LIMIT 1120
(81.062316894531): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794883 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794883 AND published='1'
LIMIT 1121
(52.928924560547): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794883 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794883 AND published='1'
LIMIT 1122
(391.96014404297): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`123
(!!!!! 24575.94871521): SELECT
*
FROM
jos_deeppockets
WHERE
jos_deeppockets.cat = 10
AND
jos_deeppockets.type = 'deeppockets_item'
AND
jos_deeppockets.published = 1
AND
jos_deeppockets.created + INTERVAL 14 DAY >= NOW()
ORDER BY
jos_deeppockets.hits DESC
LIMIT
7124
(669.00253295898): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294794883 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294794883 AND type='deeppockets_item' AND published='1' LIMIT 1125
(!!!!! 8960.9622955322): (
SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.video != ''
AND
dp.video_source != ''
AND
dp.cat = 10
AND
dp.published = 1
AND
dp.type != 'deeppockets_item_link'
ORDER BY
created DESC
LIMIT
3
)
UNION
(
SELECT
dpa.id,
dpa.name,
dpa.title,
dpa.video,
dpa.video_source,
dpa.created
FROM
jos_deeppockets_archive AS dpa
WHERE
dpa.video != ''
AND
dpa.video_source != ''
AND
dpa.cat = 10
AND
dpa.published = 1
AND
dpa.type != 'deeppockets_item_link'
ORDER BY
created DESC
LIMIT
3
)
ORDER BY
created DESC
LIMIT
3126
(83.92333984375): (
SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.video != ''
AND
dp.video_source != ''
AND
dp.cat = 10
AND
dp.published = 1
AND
dp.type != 'deeppockets_item_link'
ORDER BY
created DESC
LIMIT
3
)
UNION
(
SELECT
dpa.id,
dpa.name,
dpa.title,
dpa.video,
dpa.video_source,
dpa.created
FROM
jos_deeppockets_archive AS dpa
WHERE
dpa.video != ''
AND
dpa.video_source != ''
AND
dpa.cat = 10
AND
dpa.published = 1
AND
dpa.type != 'deeppockets_item_link'
ORDER BY
created DESC
LIMIT
3
)
ORDER BY
created DESC
LIMIT
3127
(52.213668823242): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294803337
LIMIT 1128
(31.948089599609): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294803337
LIMIT 1129
(71.048736572266): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294803276
LIMIT 1130
(39.815902709961): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294803276
LIMIT 1131
(443.93539428711): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets_archive AS dp
WHERE
dp.id = 294803276
LIMIT 1132
(50.067901611328): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets_archive AS dp
WHERE
dp.id = 294803276
LIMIT 1133
(31.948089599609): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294802958
LIMIT 1134
(29.802322387695): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294802958
LIMIT 1135
(496.14906311035): SELECT *
FROM jos_deeppockets
WHERE 1=1
AND id=294794883
AND (type='deeppockets_item' OR type='deeppockets_item_link')
AND published='1'
LIMIT 1136
(318.05038452148): SELECT *
FROM jos_deeppockets_archive
WHERE 1=1
AND id=294794883
AND (type='deeppockets_item' OR type='deeppockets_item_link')
AND published='1'
LIMIT 1137
(36.954879760742): SELECT name FROM jos_deeppockets WHERE id=212138
(28.133392333984): SELECT name FROM jos_deeppockets WHERE id=212139
(693.08280944824): SELECT *,
DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up,
DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down
FROM jos_events
WHERE state=1
AND publish_up > NOW()
and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110)
ORDER BY publish_up ASC LIMIT 3140
(698.08959960938): SELECT *,
DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up,
DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down
FROM jos_events
WHERE state=1
AND publish_up > NOW()
and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110)
ORDER BY publish_up ASC LIMIT 3141
(106.8115234375): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794883 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794883 AND published='1'
LIMIT 1142
(118.01719665527): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794883 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794883 AND published='1'
LIMIT 1143
(!!!!! 9315.013885498): TRUNCATE TABLE jos_trademed_module144
(112.05673217773): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.cat=10
AND dp.id=294794883
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1145
(84.161758422852): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.cat=10
AND dp.id=294794883
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1146
(890.01655578613): SELECT *
FROM jos_deeppockets
WHERE 1=1
AND id=294794883
AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1147
(56.028366088867): SELECT *
FROM jos_deeppockets
WHERE 1=1
AND id=294794883
AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1148
(57.93571472168): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794883 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794883 AND published='1'
LIMIT 1149
(47.922134399414): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794883 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794883 AND published='1'
LIMIT 1150
(!!!!! 1123.1899261475): SELECT jos_item.*
FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id
WHERE 1=1
AND (jos_item.imgMini<>'')
AND jos_item.type='L'
AND jos_item.numberID= (
SELECT jos_number.id
FROM jos_number
WHERE jos_number.journalID IN (10)
and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P')
ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC
LIMIT 0,1
)
ORDER BY RAND() DESC LIMIT 6151
(75.101852416992): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794883 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794883 AND published='1'
LIMIT 1152
(59.127807617188): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794883 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794883 AND published='1'
LIMIT 1153
(47.922134399414): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294794883 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294794883 AND type='deeppockets_item' AND published='1' LIMIT 1154
(41.007995605469): select distinct links.*
from jos_textlinks links
join jos_textlinks_placement placement on links.id=placement.link_id
where journal_id=(10) and (channel_id=212 or channel_id is null)155
(36.954879760742): select distinct links.*
from jos_textlinks links
join jos_textlinks_placement placement on links.id=placement.link_id
where journal_id=(10) and (channel_id=212 or channel_id is null)156
(42.915344238281): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1157
(89.883804321289): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794883 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794883 AND published='1'
LIMIT 1158
(62.942504882812): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294794883 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294794883 AND published='1'
LIMIT 1159
(41.961669921875): select jos_twitters.link from jos_twitters where cat=10160
(34.809112548828): select jos_facebook.link from jos_facebook where cat=10161
(35.04753112793): select jos_google_plus.link from jos_google_plus where cat=10162
(35.04753112793): select jos_linkedin.link from jos_linkedin where cat=10163
(362.87307739258): update jos_bannersmanager_banner
set impmade=impmade+1
where id in(14615,14202,14203)164
(!!!!! 1259.8037719727): insert into jos_banners_delta values (14615,'2025-08-28 20:48:09','216.73.216.120','view'),(14202,'2025-08-28 20:48:09','216.73.216.120','view'),(14203,'2025-08-28 20:48:09','216.73.216.120','view')
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