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New Hybrid PET/MRI System Aims to Improve Breast Cancer Diagnosis

By MedImaging International staff writers
Posted on 10 Mar 2022

Image: Digital hybrid breast PET/MRI for enhanced diagnosis of breast cancer (Photo courtesy of HYPMED)

Breast cancer is one of the leading causes of cancer death in women and a major socioeconomic issue throughout the world. With the detection methods available today, diagnosing breast cancer early enough is still not possible in many cases. As well as the problem of detection, there is an ever-increasing need for improved non-invasive characterization of cancer. Targeted therapies require an in-depth analysis of cancer to select and guide appropriate treatment. Both, positron emission tomography (PET) and magnetic resonance imaging (MRI) can provide molecular and functional information that may be of vital importance to tailoring a patient's therapy. However, current whole-body PET/MRI systems lack the necessary sensitivity and resolution for this task. Now, HYPMED, a consortium of 10 partner organizations from Europe that includes major universities, research institutes, clinics as well as major industry and small-to-medium-sized enterprises, is developing a hybrid system of the two medical imaging modalities (MRI and PET) for improved diagnosis of breast cancer and personalized therapy control.

The HYPMED project, coordinated by the European Institute for Biomedical imaging (EIBIR, Vienna, Austria), aims to develop a radiofrequency coil that can be connected to any regular clinical MR scanner and transform the device into a high-resolution PET/MRI hybrid system, which can be used to identify even the smallest breast cancer tumors and better characterize the cancer, as well as its response to therapy. Patients will also benefit as the radiation dose of this new technology will, in contrast to other PET-MRI examinations, be comparable to a regular digital mammogram.

To achieve this, the HYPMED research team will integrate a fully digital MRI-transparent PET detector into a novel multichannel PET transparent MRI surface coil. The PET-RF insert will allow vastly improved imaging of breast cancer with high resolution and ultra-high sensitivity PET, combined with a high level of structural and functional MRI. It will also facilitate minimally invasive MRI and PET-guided targeted biopsy. With HYPMED's PET-RF insert, any regular clinical MRI scan could, upon demand, be turned into a hybrid PET system

The project will also evaluate the impact of this technology on breast cancer diagnosis, prediction, and monitoring/assessment of treatment response through a carefully designed clinical study that employs established and novel PET tracers in 250 patients. Imaging data will be correlated with established and novel molecular biomarkers and the results will be compared to those obtained from whole-body PET/MRI and PET/CT. A multidisciplinary consortium of clinical scientists, three SMEs and an industry partner will pave the way for the commercialization of HYPMED products for advanced clinical decision making in cancer patients. Once HYPMED is successful, the project's partners aim to expand this innovation to other medical applications such as prostate cancer or cardiac hybrid imaging, and introduce a paradigm shift in the field of PET/MR hybrid imaging as a whole.

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67 (36.954879760742): select jos_facebook.link from jos_facebook where cat=10

68 (36.001205444336): select jos_google_plus.link from jos_google_plus where cat=10

69 (33.855438232422): select jos_linkedin.link from jos_linkedin where cat=10

70 (50.067901611328): SELECT fid FROM jos_deeppockets WHERE id=294791940 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294791940 AND published='1' LIMIT 1

71 (41.961669921875): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

72 (349.04479980469): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294791940 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

73 (292.06275939941): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294791940 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

74 (50.067901611328): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

75 (51.021575927734): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (24.080276489258): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

89 (61.03515625): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294791940 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

90 (41.007995605469): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294791940 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

91 (32.901763916016): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

92 (65.803527832031): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (40.054321289062): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (44.822692871094): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (42.200088500977): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (37.193298339844): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

105 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

106 (86.069107055664): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791940 AND published='1' LIMIT 1

107 (71.048736572266): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791940 AND published='1' LIMIT 1

108 (72.002410888672): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294791940 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

109 (65.803527832031): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294791940 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

110 (87.02278137207): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791940 AND published='1' LIMIT 1

111 (51.021575927734): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791940 AND published='1' LIMIT 1

112 (434.87548828125): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294791940 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

113 (457.0484161377): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294791940 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

114 (67.949295043945): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294791933 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

115 (434.16023254395): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294791933 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

116 (732.8987121582): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

117 (599.86114501953): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

118 (133.03756713867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791940 AND published='1' LIMIT 1

119 (77.962875366211): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791940 AND published='1' LIMIT 1

120 (71.048736572266): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791940 AND published='1' LIMIT 1

121 (49.114227294922): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791940 AND published='1' LIMIT 1

122 (55.074691772461): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791940 AND published='1' LIMIT 1

123 (49.114227294922): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791940 AND published='1' LIMIT 1

124 (320.9114074707): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

125 (!!!!! 32489.061355591): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

126 (108.95729064941): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791940 AND published='1' LIMIT 1

127 (59.127807617188): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791940 AND published='1' LIMIT 1

128 (486.13548278809): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294791940 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294791940 AND type='deeppockets_item' AND published='1' LIMIT 1

129 (!!!!! 697938.91906738): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

130 (!!!!! 925410.98594666): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

131 (325.91819763184): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

132 (46.968460083008): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

133 (218.86825561523): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

134 (36.954879760742): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

135 (190.97328186035): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

136 (!!!!! 2852.9167175293): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

137 (349.04479980469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791940 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

138 (265.12145996094): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791940 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

139 (124.93133544922): SELECT name FROM jos_deeppockets WHERE id=212

140 (30.994415283203): SELECT name FROM jos_deeppockets WHERE id=212

141 (428.91502380371): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

142 (329.97131347656): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

143 (957.01217651367): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791940 AND published='1' LIMIT 1

144 (58.174133300781): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791940 AND published='1' LIMIT 1

145 (!!!!! 7255.0773620605): TRUNCATE TABLE jos_trademed_module

146 (163.07830810547): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294791940 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

147 (485.89706420898): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294791940 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

148 (424.86190795898): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791940 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

149 (49.829483032227): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791940 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

150 (45.061111450195): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791940 AND published='1' LIMIT 1

151 (36.001205444336): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791940 AND published='1' LIMIT 1

152 (971.79412841797): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

153 (44.822692871094): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791940 AND published='1' LIMIT 1

154 (41.007995605469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791940 AND published='1' LIMIT 1

155 (328.06396484375): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294791940 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294791940 AND type='deeppockets_item' AND published='1' LIMIT 1

156 (38.14697265625): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=0 or channel_id is null)

157 (27.179718017578): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=0 or channel_id is null)

158 (30.994415283203): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

159 (98.943710327148): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791940 AND published='1' LIMIT 1

160 (49.114227294922): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791940 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791940 AND published='1' LIMIT 1

161 (133.03756713867): select jos_twitters.link from jos_twitters where cat=10

162 (65.803527832031): select jos_facebook.link from jos_facebook where cat=10

163 (47.206878662109): select jos_google_plus.link from jos_google_plus where cat=10

164 (45.061111450195): select jos_linkedin.link from jos_linkedin where cat=10

165 (326.87187194824): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

166 (!!!!! 2132.8926086426): insert into jos_banners_delta values (14615,'2025-05-01 05:54:12','3.15.182.56','view'),(14202,'2025-05-01 05:54:12','3.15.182.56','view'),(14203,'2025-05-01 05:54:12','3.15.182.56','view')

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