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By MedImaging International staff writers Posted on 21 Dec 2021
Image: A graphical MAsS score of visceral fat (L) and muscle (R) (Photo courtesy of AMRA medical)
Novel software can analyze a patient with suspected sarcopenia using a rapid neck-to-knee magnetic resonance imaging (MRI) scan.
The AMRA medical (Linköping, Sweden) Muscle Assessment Score (MAsS) Scan is designed to measure volumetric changes in muscle mass and the diffusion of fat infiltration into the muscle. The scanning protocol is based on symmetrical chemical shift imaging, also known as two-point Dixon imaging. Acquired images consist of fat and water image pairs, as reconstructed by the software. The images are automatically calibrated and corrected for variations caused by inhomogeneity in the magnetic field and coil sensitivity.
The resulting report contains the MAsS scan, anatomic and color-coded images, and precise body composition measurements with contextual insights based on AMRA's reference database. The platform-agnostic software works across all major 1.5 and 3T MR scanners, such that output across scanners is standardized and calibrated using the fat signal as an internal reference. The value of each pixel shows the percentage of fat in it; partial-volume effects do not affect quantification, and thin layers of fat (or even diffuse infiltration) contribute to fat quantification.
In addition, AMRA automates the classification and quantification of fat and muscle groups, with segmentation based on registration between the image data volume and manually segmented prototype volumes. Body fat is divided into subcutaneous, visceral, and ectopic compartments; muscle groups are automatically classified, and the volume of each individual muscle group is obtained. Additionally, the amount of fat in any user-defined region, (e.g. a muscle or an internal organ) can be calculated also for diffuse fat infiltration.
“The AMRA MAsS Scan will greatly benefit patients by allowing clinicians to assess sarcopenia and improve patient outcomes an objectively and accurately assess muscle quality and take action,” said Eric Converse, CEO of AMRA Medical. “The beauty of the report is that it is easy-to-understand, it creates a common language among clinicians with the muscle assessment score, and adds only minutes to an already prescribed MRI.”
Sarcopenia (from the Greek, meaning "poverty of flesh") is the degenerative loss of skeletal muscle mass. Sarcopenia is characterized first by muscle atrophy, along with a reduction in muscle tissue "quality," caused by such factors as replacement of muscle fibers with fat, an increase in fibrosis, changes in muscle metabolism, oxidative stress, and degeneration of the neuromuscular junction. Combined, these changes lead to progressive loss of muscle function and frailty. Sarcopenia can be thought of as a muscular analog of osteoporosis, also caused by inactivity and counteracted by exercise. The combination of osteoporosis and sarcopenia results in the significant frailty often seen in the elderly population.
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(38.14697265625): SELECT show_live FROM jos_com_show_setting LIMIT 183
(38.14697265625): SELECT show_live FROM jos_com_show_setting LIMIT 184
(38.14697265625): SELECT show_live FROM jos_com_show_setting LIMIT 185
(37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 186
(36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 187
(38.14697265625): SELECT show_live FROM jos_com_show_setting LIMIT 188
(36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 189
(36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 190
(35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 191
(71.048736572266): SELECT fid FROM jos_deeppockets
WHERE cat=10
AND id=294791017
AND (type='deeppockets_item' OR type='deeppockets_item_link')
AND published='1'
LIMIT 192
(46.968460083008): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294791017 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 193
(86.784362792969): SELECT id,name,title
FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1
AND id != 294743300
AND id != 294743301
AND id != 294743302
AND id != 294743303
AND id != 294743304
AND id != 294743305
AND id != 294743306
AND id != 294743307
AND id != 294743308
AND id != 294743309
AND id != 294743310
AND metakey != 'aacc'
ORDER BY `ordering`94
(49.114227294922): SELECT show_live FROM jos_com_show_setting LIMIT 195
(32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 196
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 197
(29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 198
(34.809112548828): SELECT show_live FROM jos_com_show_setting LIMIT 199
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1100
(27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1101
(28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1102
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1103
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1104
(26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1105
(32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1106
(34.809112548828): SELECT show_live FROM jos_com_show_setting LIMIT 1107
(29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1108
(97.036361694336): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791017 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791017 AND published='1'
LIMIT 1109
(51.975250244141): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791017 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791017 AND published='1'
LIMIT 1110
(77.962875366211): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.cat=10
AND dp.id=294791017
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1111
(62.942504882812): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.cat=10
AND dp.id=294791017
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1112
(102.99682617188): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791017 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791017 AND published='1'
LIMIT 1113
(56.028366088867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791017 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791017 AND published='1'
LIMIT 1114
(72.002410888672): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.id=294791017
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1115
(517.84515380859): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.id=294791017
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1116
(625.1335144043): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp
LEFT JOIN jos_experts as ex
ON ex.id = dp.author
LEFT JOIN jos_deeppockets as dp2
ON dp2.id = dp.fid
WHERE dp.author != 0
AND dp.cat = 10
AND dp.published = 1
AND (
(dp.fid = 294743300)
OR (dp.fid = 294743301)
OR (dp.fid = 294743302)
OR (dp.fid = 294743303)
OR (dp.fid = 294743304)
OR (dp.fid = 294743305)
OR (dp.fid = 294743306)
OR (dp.fid = 294743307)
OR (dp.fid = 294743308)
OR (dp.fid = 294743309)
OR (dp.fid = 294743310)
)
ORDER BY RAND()
LIMIT 1117
(447.98851013184): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp
LEFT JOIN jos_experts as ex
ON ex.id = dp.author
LEFT JOIN jos_deeppockets as dp2
ON dp2.id = dp.fid
WHERE dp.author != 0
AND dp.cat = 10
AND dp.published = 1
AND (
(dp.fid = 294743300)
OR (dp.fid = 294743301)
OR (dp.fid = 294743302)
OR (dp.fid = 294743303)
OR (dp.fid = 294743304)
OR (dp.fid = 294743305)
OR (dp.fid = 294743306)
OR (dp.fid = 294743307)
OR (dp.fid = 294743308)
OR (dp.fid = 294743309)
OR (dp.fid = 294743310)
)
ORDER BY RAND()
LIMIT 1118
(111.10305786133): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791017 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791017 AND published='1'
LIMIT 1119
(92.029571533203): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791017 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791017 AND published='1'
LIMIT 1120
(169.03877258301): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791017 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791017 AND published='1'
LIMIT 1121
(57.93571472168): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791017 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791017 AND published='1'
LIMIT 1122
(81.062316894531): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791017 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791017 AND published='1'
LIMIT 1123
(66.041946411133): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791017 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791017 AND published='1'
LIMIT 1124
(287.05596923828): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`125
(!!!!! 20979.166030884): SELECT
*
FROM
jos_deeppockets
WHERE
jos_deeppockets.cat = 10
AND
jos_deeppockets.type = 'deeppockets_item'
AND
jos_deeppockets.published = 1
AND
jos_deeppockets.created + INTERVAL 14 DAY >= NOW()
ORDER BY
jos_deeppockets.hits DESC
LIMIT
7126
(122.0703125): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791017 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791017 AND published='1'
LIMIT 1127
(50.067901611328): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791017 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791017 AND published='1'
LIMIT 1128
(435.11390686035): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294791017 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294791017 AND type='deeppockets_item' AND published='1' LIMIT 1129
(!!!!! 470130.92041016): (
SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.video != ''
AND
dp.video_source != ''
AND
dp.cat = 10
AND
dp.published = 1
AND
dp.type != 'deeppockets_item_link'
ORDER BY
created DESC
LIMIT
3
)
UNION
(
SELECT
dpa.id,
dpa.name,
dpa.title,
dpa.video,
dpa.video_source,
dpa.created
FROM
jos_deeppockets_archive AS dpa
WHERE
dpa.video != ''
AND
dpa.video_source != ''
AND
dpa.cat = 10
AND
dpa.published = 1
AND
dpa.type != 'deeppockets_item_link'
ORDER BY
created DESC
LIMIT
3
)
ORDER BY
created DESC
LIMIT
3130
(144.00482177734): (
SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.video != ''
AND
dp.video_source != ''
AND
dp.cat = 10
AND
dp.published = 1
AND
dp.type != 'deeppockets_item_link'
ORDER BY
created DESC
LIMIT
3
)
UNION
(
SELECT
dpa.id,
dpa.name,
dpa.title,
dpa.video,
dpa.video_source,
dpa.created
FROM
jos_deeppockets_archive AS dpa
WHERE
dpa.video != ''
AND
dpa.video_source != ''
AND
dpa.cat = 10
AND
dpa.published = 1
AND
dpa.type != 'deeppockets_item_link'
ORDER BY
created DESC
LIMIT
3
)
ORDER BY
created DESC
LIMIT
3131
(51.975250244141): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294800513
LIMIT 1132
(30.040740966797): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294800513
LIMIT 1133
(48.87580871582): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294800359
LIMIT 1134
(56.982040405273): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294800359
LIMIT 1135
(33.855438232422): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294800361
LIMIT 1136
(27.894973754883): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294800361
LIMIT 1137
(586.03286743164): SELECT *
FROM jos_deeppockets
WHERE 1=1
AND id=294791017
AND (type='deeppockets_item' OR type='deeppockets_item_link')
AND published='1'
LIMIT 1138
(398.87428283691): SELECT *
FROM jos_deeppockets_archive
WHERE 1=1
AND id=294791017
AND (type='deeppockets_item' OR type='deeppockets_item_link')
AND published='1'
LIMIT 1139
(272.03559875488): SELECT name FROM jos_deeppockets WHERE id=212140
(36.001205444336): SELECT name FROM jos_deeppockets WHERE id=212141
(468.96934509277): SELECT *,
DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up,
DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down
FROM jos_events
WHERE state=1
AND publish_up > NOW()
and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110)
ORDER BY publish_up ASC LIMIT 3142
(423.90823364258): SELECT *,
DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up,
DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down
FROM jos_events
WHERE state=1
AND publish_up > NOW()
and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110)
ORDER BY publish_up ASC LIMIT 3143
(72.956085205078): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791017 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791017 AND published='1'
LIMIT 1144
(51.021575927734): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791017 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791017 AND published='1'
LIMIT 1145
(!!!!! 9863.8534545898): TRUNCATE TABLE jos_trademed_module146
(113.96408081055): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.cat=10
AND dp.id=294791017
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1147
(72.956085205078): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.cat=10
AND dp.id=294791017
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1148
(!!!!! 1091.0034179688): SELECT *
FROM jos_deeppockets
WHERE 1=1
AND id=294791017
AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1149
(61.03515625): SELECT *
FROM jos_deeppockets
WHERE 1=1
AND id=294791017
AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1150
(60.081481933594): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791017 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791017 AND published='1'
LIMIT 1151
(63.896179199219): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791017 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791017 AND published='1'
LIMIT 1152
(!!!!! 1446.9623565674): SELECT jos_item.*
FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id
WHERE 1=1
AND (jos_item.imgMini<>'')
AND jos_item.type='L'
AND jos_item.numberID= (
SELECT jos_number.id
FROM jos_number
WHERE jos_number.journalID IN (10)
and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P')
ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC
LIMIT 0,1
)
ORDER BY RAND() DESC LIMIT 6153
(96.08268737793): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791017 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791017 AND published='1'
LIMIT 1154
(69.141387939453): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791017 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791017 AND published='1'
LIMIT 1155
(73.909759521484): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294791017 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294791017 AND type='deeppockets_item' AND published='1' LIMIT 1156
(46.014785766602): select distinct links.*
from jos_textlinks links
join jos_textlinks_placement placement on links.id=placement.link_id
where journal_id=(10) and (channel_id=212 or channel_id is null)157
(40.054321289062): select distinct links.*
from jos_textlinks links
join jos_textlinks_placement placement on links.id=placement.link_id
where journal_id=(10) and (channel_id=212 or channel_id is null)158
(44.107437133789): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1159
(90.837478637695): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791017 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791017 AND published='1'
LIMIT 1160
(63.896179199219): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294791017 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294791017 AND published='1'
LIMIT 1161
(47.206878662109): select jos_twitters.link from jos_twitters where cat=10162
(36.001205444336): select jos_facebook.link from jos_facebook where cat=10163
(35.04753112793): select jos_google_plus.link from jos_google_plus where cat=10164
(35.04753112793): select jos_linkedin.link from jos_linkedin where cat=10165
(325.91819763184): update jos_bannersmanager_banner
set impmade=impmade+1
where id in(14615,14202,14203)166
(!!!!! 1410.0074768066): insert into jos_banners_delta values (14615,'2025-05-12 12:58:24','3.148.233.239','view'),(14202,'2025-05-12 12:58:24','3.148.233.239','view'),(14203,'2025-05-12 12:58:24','3.148.233.239','view')
Expo
.jpg "Image: CT coronary angiography for diagnosing coronary artery disease offers advantages over other diagnostic tests (Photo courtesy of 123RF)")
.jpg "Image: Exemplary illustration of the labeling and segmentation process (Photo courtesy of TUM)")
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