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BOLD MRI Can Detect Coronary Stenosis at Rest

By MedImaging International staff writers
Posted on 26 Jul 2016

Image: A patient about to undergo an MRI scan (Photo courtesy of MNT).

A new study suggests that blood oxygen-level dependent (BOLD) magnetic resonance imaging (MRI) can detect myocardial ischemia without inducing cardiac physiological or pharmacological stress.

Researchers at John Radcliffe Hospital (Oxford, United Kingdom) conducted a study to reevaluate data published in 2012 that focused more on segment-based analysis of BOLD, whereas the new analysis focused on whole-slice analysis. In the first study, which included 25 coronary artery disease (CAD) patients and 20 healthy volunteers, the researchers determined the diagnostic performance of stress BOLD imaging in identifying significant CAD.

For the present analysis, resting BOLD signal intensity was first evaluated in the derivation group, and then tested in a separate validation group of 57 patients with suspected CAD referred for diagnostic coronary angiography. The range of BOLD signals at rest for each patient was indexed to create a score that correlated with presence of CAD, with an average index of 22.6% in those with versus 15.4% for those without ischemia. The researchers therefore defined a 16.1% cutoff score that identified ischemia-causing blockages.

Upon validation, the researchers found that the BOLD model could identify blockages with 88% sensitivity, 58% specificity, and 75% overall diagnostic accuracy. It performed similarly for diagnosing anatomically-significant CAD--defined as 50% or greater stenosis--at 82% sensitivity, 61% specificity, and 75% overall diagnostic accuracy. The researchers also concluded that BOLD MRI could perform equally well at stress as at rest. The study was published in the July 2016 issue of JACC: Cardiovascular Imaging.

“Our findings are pertinent to alternative imaging modalities with the potential to identify microvascular heterogeneity, and advance the concept of a functional assessment of CAD being performed at rest,” concluded lead author Jayant Ranjit Arnold, BMBCh, MA, and colleagues. “The inability of resting myocardial blood flow to discriminate the presence of CAD indicates that the favorable diagnostic performance of resting BOLD assessment is not dependent on changes in resting myocardial blood flow.”

BOLD MRI measures the blood oxygen level dependent signal that is associated with changes in blood flow and oxygenation following neural activity. The technique is particularly helpful in neurology for patients with premotor symptoms of Parkinson’s disease (PD) such as frontal executive dysfunction. The neuroimaging provides excellent resolution and diagnostic sensitivity, and can facilitate the diagnosis of other neurodegenerative conditions, including multiple system atrophy, corticobasal degeneration, and progressive supranuclear palsy.

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64 (!!!!! 7688.045501709): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

65 (612.97416687012): SELECT fid FROM jos_deeppockets WHERE id=294765277 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294765277 AND published='1' LIMIT 1

66 (367.87986755371): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

67 (61.988830566406): select jos_twitters.link from jos_twitters where cat=10

68 (32.186508178711): select jos_facebook.link from jos_facebook where cat=10

69 (57.220458984375): select jos_google_plus.link from jos_google_plus where cat=10

70 (30.040740966797): select jos_linkedin.link from jos_linkedin where cat=10

71 (34.093856811523): SELECT fid FROM jos_deeppockets WHERE id=294765277 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294765277 AND published='1' LIMIT 1

72 (34.093856811523): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

73 (343.08433532715): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294765277 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

74 (283.95652770996): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294765277 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

75 (!!!!! 1424.0741729736): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

76 (829.93507385254): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (65.088272094727): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (43.153762817383): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (180.95970153809): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (456.09474182129): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (61.03515625): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (33.140182495117): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (34.809112548828): SELECT show_live FROM jos_com_show_setting LIMIT 1

89 (46.014785766602): SELECT show_live FROM jos_com_show_setting LIMIT 1

90 (469.92301940918): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294765277 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

91 (117.06352233887): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294765277 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

92 (297.06954956055): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

93 (700.95062255859): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (57.93571472168): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (!!!!! 1662.9695892334): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (58.174133300781): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (857.11479187012): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (39.815902709961): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (446.08116149902): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (494.00329589844): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (46.014785766602): SELECT show_live FROM jos_com_show_setting LIMIT 1

105 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

106 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

107 (!!!!! 1343.0118560791): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294765277 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294765277 AND published='1' LIMIT 1

108 (364.06517028809): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294765277 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294765277 AND published='1' LIMIT 1

109 (!!!!! 1636.0282897949): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294765277 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

110 (802.04010009766): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294765277 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (!!!!! 6114.9597167969): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294765277 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294765277 AND published='1' LIMIT 1

112 (196.93374633789): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294765277 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294765277 AND published='1' LIMIT 1

113 (!!!!! 3445.1484680176): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294765277 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

114 (!!!!! 1525.87890625): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294765277 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

115 (!!!!! 2017.0211791992): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

116 (!!!!! 1594.066619873): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

117 (!!!!! 11921.882629395): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294765277 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294765277 AND published='1' LIMIT 1

118 (!!!!! 11950.969696045): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294765277 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294765277 AND published='1' LIMIT 1

119 (!!!!! 6194.8299407959): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294765277 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294765277 AND published='1' LIMIT 1

120 (62.942504882812): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294765277 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294765277 AND published='1' LIMIT 1

121 (241.99485778809): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294765277 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294765277 AND published='1' LIMIT 1

122 (63.896179199219): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294765277 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294765277 AND published='1' LIMIT 1

123 (325.91819763184): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294765277 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294765277 AND published='1' LIMIT 1

124 (290.87066650391): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294765277 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294765277 AND published='1' LIMIT 1

125 (496.14906311035): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

126 (!!!!! 133157.0148468): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

127 (!!!!! 4623.8899230957): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294765277 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294765277 AND type='deeppockets_item' AND published='1' LIMIT 1

128 (!!!!! 110265.01655579): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

129 (!!!!! 2595.9014892578): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

130 (!!!!! 2067.0890808105): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

131 (880.00297546387): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

132 (!!!!! 1008.0337524414): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

133 (!!!!! 9371.9959259033): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

134 (!!!!! 4028.0818939209): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

135 (979.18510437012): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

136 (!!!!! 8293.8671112061): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

137 (!!!!! 2053.97605896): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

138 (226.97448730469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294765277 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

139 (267.02880859375): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294765277 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

140 (117.06352233887): SELECT name FROM jos_deeppockets WHERE id=212

141 (735.99815368652): SELECT name FROM jos_deeppockets WHERE id=212

142 (805.85479736328): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

143 (!!!!! 6372.9286193848): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

144 (!!!!! 6650.9246826172): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294765277 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294765277 AND published='1' LIMIT 1

145 (197.8874206543): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294765277 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294765277 AND published='1' LIMIT 1

146 (!!!!! 12611.865997314): TRUNCATE TABLE jos_trademed_module

147 (189.06593322754): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294765277 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

148 (674.00932312012): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294765277 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

149 (!!!!! 1970.0527191162): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294765277 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

150 (!!!!! 6006.0024261475): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294765277 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

151 (!!!!! 2950.90675354): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294765277 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294765277 AND published='1' LIMIT 1

152 (708.81843566895): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294765277 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294765277 AND published='1' LIMIT 1

153 (!!!!! 1727.819442749): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

154 (137.0906829834): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294765277 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294765277 AND published='1' LIMIT 1

155 (87.976455688477): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294765277 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294765277 AND published='1' LIMIT 1

156 (!!!!! 7933.1398010254): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294765277 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294765277 AND type='deeppockets_item' AND published='1' LIMIT 1

157 (85.115432739258): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

158 (41.007995605469): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

159 (34.093856811523): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

160 (181.91337585449): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294765277 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294765277 AND published='1' LIMIT 1

161 (434.87548828125): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294765277 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294765277 AND published='1' LIMIT 1

162 (158.07151794434): select jos_twitters.link from jos_twitters where cat=10

163 (33.140182495117): select jos_facebook.link from jos_facebook where cat=10

164 (30.994415283203): select jos_google_plus.link from jos_google_plus where cat=10

165 (28.133392333984): select jos_linkedin.link from jos_linkedin where cat=10

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