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Study Suggests Saturated Fatty Acid Levels Linked to Breast Cancer

By MedImaging International staff writers
Posted on 07 Jun 2016

Image: Analysis results of a post-menopausal woman with a benign lesion and a post-menopausal woman with invasive ductal carcinoma, using the new MRI technique (Photo courtesy of RSNA).

The results of a new study, published in the June 7, 2016, online issue of the journal Radiology, may help researchers find underlying pathways of the development of breast cancer in some patients.

Researchers have previously studied the role of fat in the development and growth of breast cancer extensively using measurements of Body Mass Index (BMI) and the intake of dietary fat. The researchers enrolled 89 patients for the final analysis of the study – 58 pre-menopausal women, and 31 post-menopausal women. The researchers evaluated the BMI of each patient and the status of their breast cancer.

The researchers from the NYU Langone Medical Center (NY, NY, USA) performed the measurements using a new innovative Magnetic Resonance Imaging (MRI) technique called gradient-echo spectroscopic imaging that they developed. The novel technique enabled them to estimate fractions of different types of fat in breast adipose tissue during a clinical breast MRI exam.

The results showed that the breast tissue of post-menopausal women with invasive ductal carcinoma had a lower proportion of monounsaturated fatty acids and a greater proportion of saturated fatty acids than in post-menopausal women with benign breast tissue. Post-menopausal women with benign lesions had significantly higher levels of polyunsaturated fatty acids in their breast tissue, and lower levels of saturated fatty acids than pre-menopausal women. The researchers could not find a correlation between BMI and fatty acid fractions in breast tissue.

Sungheon G. Kim, PhD, NYU Langone Medical Center, said, “BMI is an important risk factor for breast cancer development. While increased BMI may provide a protective effect for premenopausal women, postmenopausal women have an increased risk of developing breast cancer with increasing BMI. Our research is ongoing. We need to investigate these higher levels of saturated fat and their direct correlation with tissue estrogen levels and cancer development. The results may point to a new risk factor for breast cancer.”

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66 (30.994415283203): select jos_google_plus.link from jos_google_plus where cat=10

67 (36.001205444336): select jos_linkedin.link from jos_linkedin where cat=10

68 (32.186508178711): SELECT fid FROM jos_deeppockets WHERE id=294764478 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294764478 AND published='1' LIMIT 1

69 (31.948089599609): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

70 (313.99726867676): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294764478 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (216.96090698242): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294764478 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (46.014785766602): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (47.206878662109): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (79.870223999023): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (42.915344238281): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294764478 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (29.087066650391): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294764478 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (31.948089599609): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (75.101852416992): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (41.961669921875): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (42.915344238281): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (37.193298339844): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (42.915344238281): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (47.922134399414): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (35.762786865234): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (38.14697265625): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (133.03756713867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294764478 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294764478 AND published='1' LIMIT 1

105 (66.041946411133): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294764478 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294764478 AND published='1' LIMIT 1

106 (79.870223999023): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294764478 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (61.03515625): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294764478 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (134.22966003418): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294764478 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294764478 AND published='1' LIMIT 1

109 (67.949295043945): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294764478 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294764478 AND published='1' LIMIT 1

110 (61.988830566406): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294764478 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (627.99453735352): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294764478 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (705.00373840332): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (474.92980957031): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (135.89859008789): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294764478 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294764478 AND published='1' LIMIT 1

115 (59.843063354492): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294764478 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294764478 AND published='1' LIMIT 1

116 (61.988830566406): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294764478 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294764478 AND published='1' LIMIT 1

117 (55.074691772461): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294764478 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294764478 AND published='1' LIMIT 1

118 (67.949295043945): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294764478 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294764478 AND published='1' LIMIT 1

119 (51.975250244141): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294764478 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294764478 AND published='1' LIMIT 1

120 (61.988830566406): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294764478 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294764478 AND published='1' LIMIT 1

121 (53.167343139648): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294764478 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294764478 AND published='1' LIMIT 1

122 (325.91819763184): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 29047.012329102): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (637.05444335938): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294764478 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294764478 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 10121.10710144): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (147.10426330566): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (69.856643676758): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (43.869018554688): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (71.048736572266): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (45.061111450195): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (440.12069702148): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (56.982040405273): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (53.882598876953): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (41.007995605469): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (599.14588928223): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294764478 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (450.13427734375): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294764478 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (334.02442932129): SELECT name FROM jos_deeppockets WHERE id=212

138 (50.067901611328): SELECT name FROM jos_deeppockets WHERE id=212

139 (749.11117553711): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (741.95861816406): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (95.129013061523): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294764478 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294764478 AND published='1' LIMIT 1

142 (76.055526733398): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294764478 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294764478 AND published='1' LIMIT 1

143 (!!!!! 10100.126266479): TRUNCATE TABLE jos_trademed_module

144 (122.0703125): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294764478 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (82.015991210938): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294764478 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (!!!!! 1101.016998291): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294764478 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (83.92333984375): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294764478 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (96.08268737793): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294764478 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294764478 AND published='1' LIMIT 1

149 (67.949295043945): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294764478 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294764478 AND published='1' LIMIT 1

150 (!!!!! 1625.0610351562): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (96.08268737793): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294764478 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294764478 AND published='1' LIMIT 1

152 (66.995620727539): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294764478 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294764478 AND published='1' LIMIT 1

153 (59.843063354492): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294764478 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294764478 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (48.160552978516): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

155 (42.915344238281): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

156 (55.074691772461): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (94.890594482422): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294764478 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294764478 AND published='1' LIMIT 1

158 (66.995620727539): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294764478 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294764478 AND published='1' LIMIT 1

159 (53.882598876953): select jos_twitters.link from jos_twitters where cat=10

160 (41.007995605469): select jos_facebook.link from jos_facebook where cat=10

161 (37.908554077148): select jos_google_plus.link from jos_google_plus where cat=10

162 (41.007995605469): select jos_linkedin.link from jos_linkedin where cat=10

163 (341.17698669434): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

164 (!!!!! 1283.1687927246): insert into jos_banners_delta values (14615,'2025-06-20 23:54:06','216.73.216.120','view'),(14202,'2025-06-20 23:54:06','216.73.216.120','view'),(14203,'2025-06-20 23:54:06','216.73.216.120','view')

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