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MRI Guidance, Remote-Controlled Catheter Technology May Improve Visualization of the Brain During Stroke Treatment

By MedImaging International staff writers
Posted on 13 Aug 2014

New technology in the form of a magnetically-assisted remote-controlled catheter (MARC) has been designed to allow physicians to see and evaluate brain tissue more accurately while treating a stroke.

Investigators presented their study’s results July 29, 2014, at the Society of NeuroInterventional Surgery (SNIS) 11th annual meeting, held in Colorado Springs (CO, USA). The new findings should advance the field of neurointervention, a discipline that facilitates stroke treatment by navigating a catheter (the tubing through which clot-dissolving drugs or clot retrieval devices are applied) through the blood vessels, from a point of entry in the groin up to the problematic spot in the brain. Neurointerventionists typically undertake this approach by manually directing the catheter and visualizing its progress under conventional X-ray guidance.

With MARC, the researchers tried to determine if a remote-controlled catheter under magnetic resonance imaging (MRI) guidance could more effectively accomplish maneuvering through complex vessel anatomy, which would ultimately allow for the enhanced visualization of the brain tissue affected during a stroke. “Given that MRI is the gold standard by which we determine brain tissue viability, it is exciting that we potentially now have new MRI-compatible technology that enables us, while treating a stroke, to make real-time assessments about whether brain tissue is dead or alive,” said Steven Hetts, MD, lead study author and associate professor of radiology at the University of California, San Francisco (UCSF; USA). “The implications are numerous, including improved medical decision-making, which would naturally result in optimizing patient safety and clinical outcomes.”

To evaluate the performance of MARC, Dr. Hetts and his colleagues tried to determine mean procedure times and success data for a custom, clinical-grade MARC prototype under MRI guidance as compared to a manually-navigated catheter, under both MRI and standard X-ray guidance—each procedure utilizing a cryogel vascular model designed to simulate the main and branch blood vessels in a living human. The MRI-guided procedures were performed at 1.5 Tesla using a balanced steady-state free precession sequence in the type of clinical MRI scanner available in most hospitals.

The study findings showed that MARC was clearly visible under MRI guidance and was used to effectively complete 192 (80%) of 240 total turns around blood vessels as compared to the manually directed catheter under both MRI and X-ray guidance, at 144 (60%) of 240 total turns and 119 (74%) of 160 total turns, respectively. MARC also was faster than the manually directed catheter under MRI, with a mean procedure time of 37 seconds per turn as compared to 55 seconds, but comparable to the manually directed catheter under X-ray guidance which required a mean of 44 seconds for each turn. When assessing the time required steering the various angles of branch vessels at turns of 45°, 60°, and 75°, MARC was shown to be faster than the manually directed catheter under MRI guidance.

“Given that the success of neurointerventional stroke treatment is directly tied to how fast and accurately physicians can eliminate the impact of a clot and restore blood flow to viable portions of the brain, technology that facilitates this objective stands to be transformative,” said Dr. Hetts. “By proving that MRI-guided neurointervention could be more effective than current standard approaches to stroke treatment, we are taking a significant step forward in the advancement of our field.”

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60 (49.829483032227): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294753945 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294753945 AND published='1' LIMIT 1

61 (114.91775512695): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

62 (513.07678222656): SELECT fid FROM jos_deeppockets WHERE id=294753945 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294753945 AND published='1' LIMIT 1

63 (44.107437133789): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

64 (41.961669921875): select jos_twitters.link from jos_twitters where cat=10

65 (28.133392333984): select jos_facebook.link from jos_facebook where cat=10

66 (30.040740966797): select jos_google_plus.link from jos_google_plus where cat=10

67 (29.087066650391): select jos_linkedin.link from jos_linkedin where cat=10

68 (180.00602722168): SELECT fid FROM jos_deeppockets WHERE id=294753945 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294753945 AND published='1' LIMIT 1

69 (44.107437133789): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

70 (345.94535827637): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294753945 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (257.96890258789): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294753945 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (41.961669921875): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (50.067901611328): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (44.107437133789): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (41.007995605469): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (41.961669921875): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (29.802322387695): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (44.822692871094): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294753945 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (30.994415283203): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294753945 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (40.054321289062): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (79.870223999023): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (33.855438232422): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (33.140182495117): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (46.968460083008): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (41.961669921875): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (39.100646972656): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (39.100646972656): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (77.009201049805): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294753945 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294753945 AND published='1' LIMIT 1

105 (66.995620727539): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294753945 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294753945 AND published='1' LIMIT 1

106 (53.882598876953): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294753945 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (49.829483032227): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294753945 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (133.03756713867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294753945 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294753945 AND published='1' LIMIT 1

109 (53.882598876953): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294753945 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294753945 AND published='1' LIMIT 1

110 (65.088272094727): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294753945 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (689.98336791992): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294753945 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (536.91864013672): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (336.1701965332): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (77.009201049805): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294753945 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294753945 AND published='1' LIMIT 1

115 (46.014785766602): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294753945 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294753945 AND published='1' LIMIT 1

116 (163.07830810547): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294753945 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294753945 AND published='1' LIMIT 1

117 (52.928924560547): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294753945 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294753945 AND published='1' LIMIT 1

118 (67.949295043945): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294753945 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294753945 AND published='1' LIMIT 1

119 (53.167343139648): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294753945 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294753945 AND published='1' LIMIT 1

120 (77.962875366211): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294753945 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294753945 AND published='1' LIMIT 1

121 (86.069107055664): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294753945 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294753945 AND published='1' LIMIT 1

122 (325.91819763184): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 25614.976882935): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (684.97657775879): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294753945 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294753945 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 10321.855545044): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (111.81831359863): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (65.088272094727): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (41.007995605469): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (62.942504882812): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (41.961669921875): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (419.85511779785): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (78.916549682617): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (84.161758422852): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (41.007995605469): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (555.03845214844): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294753945 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (361.91940307617): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294753945 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (56.028366088867): SELECT name FROM jos_deeppockets WHERE id=212

138 (37.908554077148): SELECT name FROM jos_deeppockets WHERE id=212

139 (777.00614929199): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (715.97099304199): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (321.1498260498): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294753945 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294753945 AND published='1' LIMIT 1

142 (71.048736572266): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294753945 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294753945 AND published='1' LIMIT 1

143 (!!!!! 4398.8227844238): TRUNCATE TABLE jos_trademed_module

144 (121.8318939209): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294753945 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (73.19450378418): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294753945 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (424.86190795898): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294753945 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (140.90538024902): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294753945 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (75.101852416992): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294753945 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294753945 AND published='1' LIMIT 1

149 (50.067901611328): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294753945 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294753945 AND published='1' LIMIT 1

150 (!!!!! 1425.9815216064): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (84.161758422852): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294753945 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294753945 AND published='1' LIMIT 1

152 (59.127807617188): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294753945 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294753945 AND published='1' LIMIT 1

153 (43.153762817383): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294753945 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294753945 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (36.954879760742): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

155 (34.093856811523): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

156 (48.160552978516): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (315.18936157227): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294753945 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294753945 AND published='1' LIMIT 1

158 (379.80079650879): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294753945 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294753945 AND published='1' LIMIT 1

159 (55.074691772461): select jos_twitters.link from jos_twitters where cat=10

160 (49.114227294922): select jos_facebook.link from jos_facebook where cat=10

161 (52.928924560547): select jos_google_plus.link from jos_google_plus where cat=10

162 (44.107437133789): select jos_linkedin.link from jos_linkedin where cat=10

163 (365.9725189209): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

164 (970.84045410156): insert into jos_banners_delta values (14615,'2025-06-24 01:20:40','216.73.216.120','view'),(14202,'2025-06-24 01:20:40','216.73.216.120','view'),(14203,'2025-06-24 01:20:40','216.73.216.120','view')

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