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MRI’s Magnetic Fields Used to Treat Balance Problems

By MedImaging International staff writers
Posted on 15 Apr 2014

Investigators, expanding on earlier studies, reported that individuals with balance disorders or dizziness traceable to an inner-ear disturbance show distinctive abnormal eye movements when the affected ear is exposed to the strong pull of a magnetic resonance imaging scanner’s (MRI) magnetic field.

The researchers first reported in 2011 in the journal Current Biology that an MRI’s magnetic field pushes on the inner ear fluid responsible for maintaining balance, causing subjects undergoing MRI scans to have jerky eye movements and dizziness. Two new studies now suggest that these strong magnets could be used to diagnose, treat and study inner ear disorders in the future, replacing more invasive and uncomfortable examinations.

In the first study, reported online March 13, 2014, in the journal Frontiers in Neurology, a team led by Bryan Ward, MD, a resident in the department of otolaryngology-head and neck surgery at the Johns Hopkins University School of Medicine (Baltimore, MD, USA), placed nine patients with balance problems in an MRI machine and took video of their eye movements, without taking any MRI images.

Their earlier research had shown that healthy study participants subjected to a 7 Tesla magnetic field—the strength of the most modern MRI scanner—experienced a distinctive eye movement called nystagmus, in which the eyes repeatedly drift to one side and then jerk back. This time, the researchers were curious whether this movement might look different in patients with inner ear problems, whose semicircular canals would likely react differently to the MRI magnet’s pull.

While healthy, normal volunteers’ eyes moved side to side when in the MRI, with the direction of movement dependent on whether they entered the MRI tunnel head or feet first, people with “one-sided” inner ear problems displayed different eye movements that depended on which ear was affected. For example, according to Dr. Ward, the eyes of patients whose left ear was affected drifted down and jerked up when put into the MRI tunnel head first. Those whose right ear was affected had an opposite movement. Both sets of patients showed patterns of rapid eye motions not seen in the healthy volunteers.

Because the abnormal findings consistently showed which ear was affected in the patients, according to Dr. Ward, researchers may eventually be able to use magnetic stimulation to diagnose the cause of balance disorders. Currently, people whose dizziness or imbalance is suspected to originate in the inner ear may have eye movements measured after being spun around in a chair, tilted backward on special tables, or subjected to at times uncomfortable ear canal irrigation with cold or warm water.

Magnetic stimulation, acting as a virtual reality stimulator, could also offer an alternative to traditional physical therapy for balance disorders, which often involve rapid head movements that make patients dizzy. “Using magnetic stimulation, perhaps in a portable device that could fit in a doctor's office, could offer an alternative that’s more comfortable,” Dr. Ward stated.

In a second study, published March 19, 2014, in the journal PLOS One, Dr. Ward and his colleagues set out to investigate whether the inner ear balance systems of zebrafish are also influenced by magnetic stimulation. Zebrafish are a prevalent model for genetics and pharmaceutical studies of hearing and balance because of their surprising anatomical similarity to humans’ vestibular systems, according to Dr. Ward.

If the inner ears of these fish were also affected by a strong magnet’s pull, he says, these animals could eventually be a useful tool for studying which genes are involved in inherited inner ear balance problems or which drugs could be used to treat these disorders. To study this, the researchers placed 30 healthy zebrafish, one at a time, into a very strong 11.7 Tesla magnetic field, using a smaller MRI machine to better accommodate the aquarium used to hold each fish.

When the aquarium was in the magnetic field, the majority of fish responded in a dramatic way akin to the vertigo and imbalance that humans with inner ear system disturbances show: The fish flipped, rolled and swam faster than normal. The fish reverted to normal swimming behavior only when their aquarium was taken out of the MRI machine and away from the magnet.

To ascertain that this behavior was not due to any vision changes or effects on the lateral line—an organ on the side of the body of a fish important for helping the animals maintain posture or sense electrical currents in the water—the researchers turned lights on and off every 30 seconds while the fish were in the magnetic field and also had them swim in the magnetic field after they had been exposed to gentamicin, an antibiotic that destroys lateral line cells. Neither experiment changed the animals’ strange swimming behavior in the magnetic field.

The researchers additionally observed that individual fish seemed to be affected by the orientation of the magnetic field, swimming preferentially either in the direction of the magnetic field or in an opposite orientation. For instance, some of the animals preferred to swim north-south in a north-south field, while others chose to swim east-west. Putting the animals into an opposing field did not affect their preference. These results could add insight into the scientific field of magnetosensation, which studies how some animals are able to sense the Earth’s magnetic field and use it for purposes such as migration, Dr. Ward noted.

Overall, the findings in humans and fish could eventually lead to useful ways to harness the effect of an MRI magnet on the inner ear. “We may someday have some practical applications for this anatomical oddity,” Dr. Ward said.

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55 (249.14741516113): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294751810 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

56 (675.91667175293): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294751810 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

57 (!!!!! 6917.9534912109): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294751810 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294751810 AND published='1' LIMIT 1

58 (153.0647277832): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294751810 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294751810 AND published='1' LIMIT 1

59 (!!!!! 2855.0624847412): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294751810 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294751810 AND published='1' LIMIT 1

60 (66.995620727539): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294751810 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294751810 AND published='1' LIMIT 1

61 (321.1498260498): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

62 (631.80923461914): SELECT fid FROM jos_deeppockets WHERE id=294751810 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294751810 AND published='1' LIMIT 1

63 (442.9817199707): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

64 (740.05126953125): select jos_twitters.link from jos_twitters where cat=10

65 (!!!!! 1066.2078857422): select jos_facebook.link from jos_facebook where cat=10

66 (61.03515625): select jos_google_plus.link from jos_google_plus where cat=10

67 (47.922134399414): select jos_linkedin.link from jos_linkedin where cat=10

68 (69.141387939453): SELECT fid FROM jos_deeppockets WHERE id=294751810 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294751810 AND published='1' LIMIT 1

69 (68.902969360352): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

70 (389.81437683105): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294751810 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (297.06954956055): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294751810 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (58.889389038086): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (!!!!! 2128.8394927979): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (99.18212890625): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (51.021575927734): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (38.862228393555): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (41.007995605469): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (40.054321289062): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (50.067901611328): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (42.915344238281): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (45.061111450195): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (39.100646972656): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (41.961669921875): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (43.869018554688): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (38.862228393555): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (38.14697265625): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (92.029571533203): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294751810 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (51.021575927734): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294751810 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (56.028366088867): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (72.002410888672): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (46.968460083008): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (45.061111450195): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (79.154968261719): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (33.140182495117): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (29.802322387695): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (120.87821960449): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294751810 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294751810 AND published='1' LIMIT 1

105 (85.830688476562): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294751810 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294751810 AND published='1' LIMIT 1

106 (113.01040649414): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294751810 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (71.048736572266): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294751810 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (!!!!! 2348.8998413086): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294751810 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294751810 AND published='1' LIMIT 1

109 (97.990036010742): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294751810 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294751810 AND published='1' LIMIT 1

110 (100.85105895996): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294751810 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (884.05609130859): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294751810 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (!!!!! 1151.0848999023): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (701.904296875): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (!!!!! 5081.1767578125): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294751810 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294751810 AND published='1' LIMIT 1

115 (!!!!! 3937.0059967041): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294751810 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294751810 AND published='1' LIMIT 1

116 (263.92936706543): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294751810 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294751810 AND published='1' LIMIT 1

117 (!!!!! 1153.9459228516): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294751810 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294751810 AND published='1' LIMIT 1

118 (125.88500976562): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294751810 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294751810 AND published='1' LIMIT 1

119 (219.10667419434): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294751810 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294751810 AND published='1' LIMIT 1

120 (108.00361633301): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294751810 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294751810 AND published='1' LIMIT 1

121 (620.12672424316): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294751810 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294751810 AND published='1' LIMIT 1

122 (296.83113098145): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 95259.90486145): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (717.8783416748): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294751810 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294751810 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 21785.020828247): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (!!!!! 5043.0297851562): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (264.16778564453): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (!!!!! 3538.1317138672): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (304.9373626709): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (128.03077697754): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (187.87384033203): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (55.074691772461): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (185.01281738281): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (40.054321289062): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (380.9928894043): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294751810 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (249.86267089844): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294751810 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (226.02081298828): SELECT name FROM jos_deeppockets WHERE id=212

138 (46.014785766602): SELECT name FROM jos_deeppockets WHERE id=212

139 (751.01852416992): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (681.16188049316): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (149.01161193848): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294751810 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294751810 AND published='1' LIMIT 1

142 (51.021575927734): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294751810 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294751810 AND published='1' LIMIT 1

143 (!!!!! 7475.1377105713): TRUNCATE TABLE jos_trademed_module

144 (!!!!! 3170.0134277344): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294751810 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (138.0443572998): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294751810 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (588.17863464355): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294751810 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (57.93571472168): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294751810 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (77.962875366211): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294751810 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294751810 AND published='1' LIMIT 1

149 (45.061111450195): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294751810 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294751810 AND published='1' LIMIT 1

150 (!!!!! 5416.8701171875): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (97.036361694336): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294751810 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294751810 AND published='1' LIMIT 1

152 (62.942504882812): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294751810 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294751810 AND published='1' LIMIT 1

153 (46.014785766602): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294751810 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294751810 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (36.954879760742): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

155 (34.093856811523): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

156 (39.100646972656): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (!!!!! 1453.161239624): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294751810 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294751810 AND published='1' LIMIT 1

158 (67.949295043945): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294751810 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294751810 AND published='1' LIMIT 1

159 (184.05914306641): select jos_twitters.link from jos_twitters where cat=10

160 (38.14697265625): select jos_facebook.link from jos_facebook where cat=10

161 (31.948089599609): select jos_google_plus.link from jos_google_plus where cat=10

162 (26.941299438477): select jos_linkedin.link from jos_linkedin where cat=10

163 (524.04403686523): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

164 (!!!!! 5342.0066833496): insert into jos_banners_delta values (14615,'2025-06-24 06:32:13','216.73.216.120','view'),(14202,'2025-06-24 06:32:13','216.73.216.120','view'),(14203,'2025-06-24 06:32:13','216.73.216.120','view')

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