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AAPM 2025 - 67th Annual Meeting & Exhibition of the American Association of Physicists in Medicine

MRI Fingerprint Technology Offers Early Detection of Disease

By MedImaging International staff writers
Posted on 25 Mar 2013

Magnetic resonance imaging (MRI) could routinely identify specific cancers, multiple sclerosis, heart disease, and other disorders early, when they are most treatable.

Each body tissue and disease has a unique fingerprint that can be used to diagnose problems rapidly, scientists from Case Western Reserve University (Cleveland, OH, USA) and University Hospitals (UH) Case Medical Center suggest in their article published March 2013 in the journal Nature. By using new MRI technologies to scan for different physical properties at the same time, the researches distinguished white matter from gray matter from cerebrospinal fluid (CSF) in the brain in about 12 seconds, with the promise of doing this much faster in the near future.

The technology has the potential to make an MRI scan standard procedure in annual check-ups, the authors believe. A full-body scan lasting only minutes would provide a lot more data and require no radiologist to interpret the data, making diagnostics inexpensive, compared to current scans, they argued. “The overall goal is to specifically identify individual tissues and diseases, to hopefully see things and quantify things before they become a problem,” said Dr. Mark Griswold, a radiology professor at Case Western Reserve School of Medicine and UH Case Medical Center. “But to try to get there, we’ve had to give up everything we knew about the MRI and start over.”

Magnetic resonance fingerprinting (MRF) can gather much more data with each measurement than a conventional MRI can. Dr. Griswold compares the difference in technologies to a couple of choirs. “In the traditional MRI, everyone is singing the same song and you can tell who is singing louder, who is off-pitch, who is singing softer,” he said. “But that’s about it.”

The louder, softer, and off-pitch singing is represented by dark, light, or bright spots in the scan that a radiologist must decode. An MRI scan, for instance, would reveal swelling as a bright area in an image. But brightness does not inevitably compare with cause or severity of disease. “With an MRF, we hope that with one step we can tell the severity and exactly what’s happening in that area,” remarked Dr. Griswold.

The fingerprint of each tissue, each disease, and each substance inside the body is therefore a different song. In an MRF, each member of the choir sings a different song simultaneously, Dr. Griswold stated. “What it sounds like in total is a randomized mess.”

The researchers generate distinct songs by simultaneously varying different parts of the input electromagnetic fields that probe the tissues. These variations make the received signal sensitive to four physical properties that vary from tissue to tissue. These differences—the different notes and lyrics of their songs—become evident when applying pattern recognition programs using the same math in facial recognition software.

The patterns are then mapped. Instead of looking at relative measurements from an image, Griswold said quantitative estimates told one tissue from another. As the technology progresses, these findings should determine whether tissue is healthy or diseased, how seriously and by what process. The scientists believe that they will be able to interrogate a total of eight or nine physical properties that will allow them to produce the songs from a huge range of tissues, diseases, and materials.

For a patient, an MRF would seem similar to a fast MRI. When the scan is performed, all of the patient’s songs would be compared with the songbook, which will provide physicians with a range of diagnostic data. “If colon cancer is ‘Happy Birthday’ and we don’t hear ‘Happy Birthday,’ the patient doesn’t have colon cancer,” Dr. Griswold said.

Other researchers have tried to employ multiple parameters in MRI scans, but this group was able to scan fast and with higher sensitivity than in earlier efforts, he continued. “This research gives us hope. We can see that it’s possible the MRI can see all sorts of things.”

The group expects to reduce scanning time and continue to build the library of fingerprints over the next few years. Case Western Reserve and UH Case Medical Center have a 31-year history of developing MRI technology with Siemens Healthcare (Erlangen, Germany).

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58 (62.942504882812): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294745354 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294745354 AND published='1' LIMIT 1

59 (!!!!! 2128.1242370605): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294745354 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294745354 AND published='1' LIMIT 1

60 (74.148178100586): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294745354 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294745354 AND published='1' LIMIT 1

61 (619.88830566406): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

62 (!!!!! 3497.838973999): SELECT fid FROM jos_deeppockets WHERE id=294745354 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294745354 AND published='1' LIMIT 1

63 (!!!!! 2712.0113372803): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

64 (195.02639770508): select jos_twitters.link from jos_twitters where cat=10

65 (31.948089599609): select jos_facebook.link from jos_facebook where cat=10

66 (112.05673217773): select jos_google_plus.link from jos_google_plus where cat=10

67 (34.809112548828): select jos_linkedin.link from jos_linkedin where cat=10

68 (30.994415283203): SELECT fid FROM jos_deeppockets WHERE id=294745354 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294745354 AND published='1' LIMIT 1

69 (30.994415283203): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

70 (218.15299987793): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294745354 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (167.8466796875): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294745354 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (89.168548583984): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (276.08871459961): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (124.93133544922): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (175.95291137695): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (29.802322387695): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (113.01040649414): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (360.96572875977): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (188.82751464844): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294745354 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (122.0703125): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294745354 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (33.855438232422): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (53.167343139648): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (48.87580871582): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (180.95970153809): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (!!!!! 1044.9886322021): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294745354 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294745354 AND published='1' LIMIT 1

105 (61.988830566406): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294745354 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294745354 AND published='1' LIMIT 1

106 (51.021575927734): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294745354 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (46.014785766602): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294745354 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (442.9817199707): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294745354 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294745354 AND published='1' LIMIT 1

109 (139.95170593262): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294745354 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294745354 AND published='1' LIMIT 1

110 (273.9429473877): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294745354 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (468.01567077637): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294745354 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (755.07164001465): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (478.02925109863): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (147.10426330566): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294745354 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294745354 AND published='1' LIMIT 1

115 (62.942504882812): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294745354 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294745354 AND published='1' LIMIT 1

116 (92.029571533203): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294745354 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294745354 AND published='1' LIMIT 1

117 (60.081481933594): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294745354 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294745354 AND published='1' LIMIT 1

118 (71.048736572266): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294745354 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294745354 AND published='1' LIMIT 1

119 (49.829483032227): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294745354 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294745354 AND published='1' LIMIT 1

120 (71.048736572266): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294745354 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294745354 AND published='1' LIMIT 1

121 (119.92454528809): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294745354 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294745354 AND published='1' LIMIT 1

122 (324.01084899902): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 57109.117507935): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (!!!!! 4035.9497070312): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294745354 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294745354 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 19767.045974731): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (53.882598876953): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (39.100646972656): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (32.901763916016): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (41.007995605469): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (32.901763916016): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (302.79159545898): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (36.954879760742): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (35.04753112793): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (31.948089599609): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (524.99771118164): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294745354 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (329.97131347656): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294745354 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (36.954879760742): SELECT name FROM jos_deeppockets WHERE id=212

138 (29.087066650391): SELECT name FROM jos_deeppockets WHERE id=212

139 (601.05323791504): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (451.80320739746): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (69.856643676758): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294745354 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294745354 AND published='1' LIMIT 1

142 (44.107437133789): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294745354 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294745354 AND published='1' LIMIT 1

143 (!!!!! 7550.9548187256): TRUNCATE TABLE jos_trademed_module

144 (77.009201049805): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294745354 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (56.028366088867): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294745354 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (758.88633728027): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294745354 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (47.206878662109): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294745354 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (57.220458984375): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294745354 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294745354 AND published='1' LIMIT 1

149 (39.815902709961): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294745354 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294745354 AND published='1' LIMIT 1

150 (!!!!! 1121.997833252): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (52.928924560547): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294745354 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294745354 AND published='1' LIMIT 1

152 (42.200088500977): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294745354 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294745354 AND published='1' LIMIT 1

153 (31.948089599609): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294745354 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294745354 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (29.087066650391): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

155 (25.98762512207): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

156 (27.894973754883): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (529.05082702637): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294745354 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294745354 AND published='1' LIMIT 1

158 (54.836273193359): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294745354 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294745354 AND published='1' LIMIT 1

159 (36.001205444336): select jos_twitters.link from jos_twitters where cat=10

160 (30.994415283203): select jos_facebook.link from jos_facebook where cat=10

161 (32.186508178711): select jos_google_plus.link from jos_google_plus where cat=10

162 (30.994415283203): select jos_linkedin.link from jos_linkedin where cat=10

163 (261.06834411621): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

164 (!!!!! 1028.0609130859): insert into jos_banners_delta values (14615,'2025-06-25 19:29:09','216.73.216.120','view'),(14202,'2025-06-25 19:29:09','216.73.216.120','view'),(14203,'2025-06-25 19:29:09','216.73.216.120','view')

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