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AAPM 2025 - 67th Annual Meeting & Exhibition of the American Association of Physicists in Medicine

Nanoscale MRI Devised to Be Similar to an Atomic Force Microscope

By MedImaging International staff writers
Posted on 26 Feb 2013

Image: A tiny defect inside a diamond, called a nitrogen vacancy (NV), enabled researchers to detect the magnetic resonance of organic molecules in the same way an MRI produces images of a tissue or an organ (Photo courtesy of T. Staudacher and F. Reinhard).

German and American scientists have opened the possibility for nanoscale magnetic resonance imaging (MRI) by exploiting the minuscule flaws in diamonds to sense the magnetic resonance properties of molecules.

MRI shows the tiny specifics of living tissues, tumors, diseased organs inside the body without the need for surgery or X-rays. This new technology could potentially visualize down to the level of atoms. Clinicians could make visual diagnoses of an individual’s molecules—examining damage on a strand of DNA, watching molecules misfold, or identifying a cancer cell by the proteins on its surface.

Dr. Carlos Meriles, associate professor of physics at the City College of New York (NY, USA), and an international team of researchers at the University of Stuttgart (Germany) have published their new findings in the February 1, 2013, issue of the journal Science.

“It is bringing MRI to a level comparable to an atomic force microscope,” said Prof. Meriles, referring to the device that tracks the shape of atoms or the pull on a molecule to measure its strength. A nanoscale MRI could display how a molecule moves without touching it. Standard MRI typically gets to a resolution of 100 microns,” about the width of a human hair, said Prof. Meriles. “With extraordinary effort, it can get down to about 10 microns”—the width of a couple of blood cells. Nanoscale MRI would have a resolution 1,000 to 10,000 times better.

To try to capture magnetic resonance on such a small level, the investigators took advantage of the spin of protons in an atom, a characteristic typically used to study quantum computing. Specifically, they used miniscule imperfections in diamonds. Diamonds are crystals comprised of nearly entirely of carbon atoms. When a nitrogen atom stays next to an area where a carbon atom is missing, however, it creates a defect known as a nitrogen-vacancy (NV) center.

“These imperfections turn out to have a spin—like a little compass—and have some remarkable properties,” noted Prof. Meriles. In the last few years, researchers realized that these NV centers could serve as very sensitive sensors. They can pick up the magnetic resonance of nearby atoms in a cell, for example. But unlike the atoms in a cell, the NVs shine when a light is directed at them, signaling what their spin is. If you illuminate it with green light it flashes red back. “It is a form of what is called optically detected magnetic resonance,” he said. Similar to a boat flashing Morse code on the sea, the sensor “sends back flashes to say it is alive and well.”

Prof. Mireles has written on the hypothetic foundations of the research and proposed the project to the scientists, led by Prof. Jörg Wrachtrup, a physicist at the University of Stuttgart, with the help of postdoctoral researcher Friedemann Reinhard and collaborators from the University of Bochum (Germany) and the University of Science and Technology of China (Hefei, Anhui). Prof. Wrachtrup is head of a leading group studying such defects.

“The NV can also be thought of as an atomic magnet. You can manipulate the spin of that atomic magnet just like you do with MRI by applying a radio frequency or radio pulses,” Prof. Meriles explained. The NV responds, such as when one shines a green light at it when the spin is pointing up, it will respond with brighter red light. A down spin gives a dimmer red light.

Tobias Staudacher, a graduate student, and the first author in this study, employed NVs in the laboratory that had been created just below the diamond’s surface by bombarding it with nitrogen atoms. The scientists identified MR within a film of organic substance applied to the surface, just as one might study a thin film of cells or tissue.

“Ultimately,” concluded Prof. Meriles, “One will use a nitrogen-vacancy mounted on the tip of an atomic force microscope—or an array of NVs distributed on the diamond surface—to allow a scanning view of a cell, for example, to probe nuclear spins with a resolution down to a nanometer or perhaps better.”

Related Links:
City College of New York
University of Stuttgart
University of Bochum

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56 (463.96255493164): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294744937 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

57 (!!!!! 1194.953918457): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294744937 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294744937 AND published='1' LIMIT 1

58 (60.796737670898): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294744937 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294744937 AND published='1' LIMIT 1

59 (167.8466796875): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294744937 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294744937 AND published='1' LIMIT 1

60 (66.041946411133): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294744937 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294744937 AND published='1' LIMIT 1

61 (!!!!! 5393.0282592773): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

62 (647.06802368164): SELECT fid FROM jos_deeppockets WHERE id=294744937 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294744937 AND published='1' LIMIT 1

63 (364.06517028809): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

64 (67.949295043945): select jos_twitters.link from jos_twitters where cat=10

65 (30.040740966797): select jos_facebook.link from jos_facebook where cat=10

66 (32.186508178711): select jos_google_plus.link from jos_google_plus where cat=10

67 (27.894973754883): select jos_linkedin.link from jos_linkedin where cat=10

68 (34.093856811523): SELECT fid FROM jos_deeppockets WHERE id=294744937 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294744937 AND published='1' LIMIT 1

69 (36.954879760742): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

70 (375.98609924316): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294744937 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (252.96211242676): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294744937 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (51.975250244141): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (77.962875366211): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (42.915344238281): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (41.961669921875): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (39.100646972656): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (34.809112548828): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (33.855438232422): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (57.93571472168): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (33.855438232422): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (47.922134399414): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (47.922134399414): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294744937 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (28.848648071289): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294744937 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (32.901763916016): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (46.968460083008): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (33.855438232422): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (66.995620727539): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294744937 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294744937 AND published='1' LIMIT 1

105 (92.983245849609): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294744937 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294744937 AND published='1' LIMIT 1

106 (63.180923461914): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294744937 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (!!!!! 1245.0218200684): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294744937 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (!!!!! 2841.9494628906): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294744937 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294744937 AND published='1' LIMIT 1

109 (96.797943115234): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294744937 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294744937 AND published='1' LIMIT 1

110 (72.002410888672): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294744937 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (705.00373840332): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294744937 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (621.08039855957): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (381.9465637207): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (75.101852416992): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294744937 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294744937 AND published='1' LIMIT 1

115 (62.942504882812): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294744937 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294744937 AND published='1' LIMIT 1

116 (50.067901611328): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294744937 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294744937 AND published='1' LIMIT 1

117 (41.961669921875): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294744937 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294744937 AND published='1' LIMIT 1

118 (58.889389038086): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294744937 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294744937 AND published='1' LIMIT 1

119 (40.054321289062): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294744937 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294744937 AND published='1' LIMIT 1

120 (51.975250244141): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294744937 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294744937 AND published='1' LIMIT 1

121 (41.007995605469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294744937 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294744937 AND published='1' LIMIT 1

122 (273.9429473877): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 41156.053543091): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (962.0189666748): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294744937 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294744937 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 15882.015228271): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (355.00526428223): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (122.7855682373): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (455.85632324219): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (114.91775512695): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (128.03077697754): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (!!!!! 1281.0230255127): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (301.83792114258): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (106.0962677002): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (391.00646972656): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (404.11949157715): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294744937 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (610.8283996582): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294744937 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (244.8558807373): SELECT name FROM jos_deeppockets WHERE id=212

138 (35.04753112793): SELECT name FROM jos_deeppockets WHERE id=212

139 (656.1279296875): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (597.00012207031): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (258.9225769043): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294744937 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294744937 AND published='1' LIMIT 1

142 (152.1110534668): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294744937 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294744937 AND published='1' LIMIT 1

143 (!!!!! 17135.143280029): TRUNCATE TABLE jos_trademed_module

144 (!!!!! 2743.9594268799): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294744937 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (84.877014160156): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294744937 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (335.9317779541): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294744937 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (154.01840209961): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294744937 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (56.028366088867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294744937 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294744937 AND published='1' LIMIT 1

149 (41.007995605469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294744937 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294744937 AND published='1' LIMIT 1

150 (!!!!! 1067.1615600586): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (55.074691772461): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294744937 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294744937 AND published='1' LIMIT 1

152 (52.928924560547): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294744937 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294744937 AND published='1' LIMIT 1

153 (39.100646972656): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294744937 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294744937 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (29.087066650391): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

155 (27.179718017578): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

156 (35.04753112793): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (!!!!! 2903.2230377197): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294744937 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294744937 AND published='1' LIMIT 1

158 (79.154968261719): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294744937 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294744937 AND published='1' LIMIT 1

159 (!!!!! 2816.915512085): select jos_twitters.link from jos_twitters where cat=10

160 (63.896179199219): select jos_facebook.link from jos_facebook where cat=10

161 (33.140182495117): select jos_google_plus.link from jos_google_plus where cat=10

162 (27.179718017578): select jos_linkedin.link from jos_linkedin where cat=10

163 (303.98368835449): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

164 (985.86082458496): insert into jos_banners_delta values (14615,'2025-06-25 20:39:09','216.73.216.120','view'),(14202,'2025-06-25 20:39:09','216.73.216.120','view'),(14203,'2025-06-25 20:39:09','216.73.216.120','view')

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