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In Postconcussion Syndrome Patients, MRI Reveals Brain Disruption

By MedImaging International staff writers
Posted on 10 Dec 2012

Magnetic resonance imaging (MRI) scans are showing changes in the brains of individuals with postconcussion syndrome (PCS), according to new research. Researchers hope these new findings lead to improved detection and treatment for the disorder.

PCS affects approximately 20%–30% of people who suffer mild traumatic brain injury (MTBI) — classified by the World Health Organization (Geneva, Switzerland) as a traumatic event causing brief loss of consciousness and/or transient memory dysfunction or disorientation. Symptoms of PCS include poor concentration, headache, and problems with memory.

The study’s findings were published online November 25, 2012, in the journal Radiology. Traditional neuroimaging modalities cannot differentiate which MTBI patients will develop PCS. “Conventional imaging with CT [computed tomography] or MRI is pretty much normal in MTBI patients, even though some go on to develop symptoms, including severe cognitive problems,” said Yulin Ge, MD, associate professor, department of radiology at the New York University (NYU) School of Medicine (New York, NY, USA). “We want to try to better understand why and how these symptoms arise.”

Dr. Ge’s study used MRI to visualize at the brain during its resting state (when it is not engaged in a specific task), such as when the mind daydreams or meanders. The resting state is believed to involve connections among a number of regions, with the default mode network (DMN) playing an especially significant function. “Baseline DMN is very important for information processing and maintenance,” Dr. Ge noted.

Alterations in DMN have been found in several psychiatric disorders, including autism, Alzheimer’s disease, and schizophrenia, but not much is known about DMN connectivity changes in MTBI. Dr. Ge and colleagues employed resting-state functional MRI in this study to compare 23 MTBI patients who had post-traumatic symptoms within two months of the injury and 18 age-matched healthy controls. Resting state MRI identifies distinctive changes in baseline oxygen-level fluctuations associated with brain functional networks between patients with MTBI and control patients.

The MRI results showed that communication and information integration in the brain were disrupted among key DMN structures after mild head injury, and that the brain tapped into different neural resources to compensate for the impaired function. “We found decreased functional connectivity in the posterior network of the brain and increased connectivity in the anterior component, probably due to functional compensation in patients with PCS,” Dr. Ge said. “The reduced posterior connectivity correlated positively with neurocognitive dysfunction.”

Dr. Ge and the other investigators hope to recruit more MTBI patients for further studies with an eye toward developing a biomarker to monitor disease progression and recovery as well as treatment effects. “We want to do studies to look at the changes in the network over time and correlate these functional changes with structural changes in the brain,” he concluded. “This could give us hints on treatments to bring back cognitive function.”

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62 (545.97854614258): SELECT fid FROM jos_deeppockets WHERE id=294743766 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294743766 AND published='1' LIMIT 1

63 (384.09233093262): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

64 (92.029571533203): select jos_twitters.link from jos_twitters where cat=10

65 (37.908554077148): select jos_facebook.link from jos_facebook where cat=10

66 (32.901763916016): select jos_google_plus.link from jos_google_plus where cat=10

67 (30.040740966797): select jos_linkedin.link from jos_linkedin where cat=10

68 (31.948089599609): SELECT fid FROM jos_deeppockets WHERE id=294743766 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294743766 AND published='1' LIMIT 1

69 (33.140182495117): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

70 (472.06878662109): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294743766 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (259.1609954834): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294743766 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (52.213668823242): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (70.095062255859): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (55.074691772461): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (33.140182495117): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (66.041946411133): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (37.193298339844): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (63.180923461914): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (59.843063354492): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294743766 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (42.915344238281): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294743766 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (34.809112548828): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (54.121017456055): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (51.975250244141): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (46.014785766602): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (29.802322387695): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (70.095062255859): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743766 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743766 AND published='1' LIMIT 1

105 (41.007995605469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743766 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743766 AND published='1' LIMIT 1

106 (53.882598876953): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294743766 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (48.160552978516): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294743766 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (201.94053649902): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743766 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743766 AND published='1' LIMIT 1

109 (63.180923461914): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743766 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743766 AND published='1' LIMIT 1

110 (136.8522644043): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294743766 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (509.97734069824): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294743766 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (515.22254943848): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (336.1701965332): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (79.154968261719): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743766 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743766 AND published='1' LIMIT 1

115 (43.869018554688): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743766 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743766 AND published='1' LIMIT 1

116 (54.836273193359): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743766 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743766 AND published='1' LIMIT 1

117 (40.054321289062): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743766 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743766 AND published='1' LIMIT 1

118 (51.021575927734): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743766 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743766 AND published='1' LIMIT 1

119 (37.193298339844): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743766 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743766 AND published='1' LIMIT 1

120 (48.87580871582): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743766 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743766 AND published='1' LIMIT 1

121 (37.908554077148): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743766 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743766 AND published='1' LIMIT 1

122 (194.07272338867): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 19767.999649048): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (432.96813964844): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294743766 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294743766 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 9871.0060119629): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (68.902969360352): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (38.14697265625): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (29.087066650391): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (43.153762817383): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (41.007995605469): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (211.00044250488): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (91.075897216797): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (35.04753112793): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (27.894973754883): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (445.12748718262): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743766 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (327.11029052734): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743766 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (151.8726348877): SELECT name FROM jos_deeppockets WHERE id=212

138 (34.093856811523): SELECT name FROM jos_deeppockets WHERE id=212

139 (545.97854614258): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (512.12310791016): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (65.803527832031): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743766 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743766 AND published='1' LIMIT 1

142 (49.114227294922): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743766 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743766 AND published='1' LIMIT 1

143 (!!!!! 8808.1359863281): TRUNCATE TABLE jos_trademed_module

144 (93.936920166016): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294743766 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (54.121017456055): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294743766 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (854.9690246582): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743766 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (56.028366088867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743766 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (60.081481933594): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743766 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743766 AND published='1' LIMIT 1

149 (46.968460083008): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743766 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743766 AND published='1' LIMIT 1

150 (!!!!! 1018.0473327637): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (!!!!! 2364.1586303711): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743766 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743766 AND published='1' LIMIT 1

152 (86.069107055664): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743766 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743766 AND published='1' LIMIT 1

153 (68.902969360352): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294743766 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294743766 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (581.97975158691): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

155 (53.882598876953): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

156 (51.975250244141): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (121.11663818359): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743766 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743766 AND published='1' LIMIT 1

158 (75.101852416992): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294743766 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294743766 AND published='1' LIMIT 1

159 (!!!!! 1274.8241424561): select jos_twitters.link from jos_twitters where cat=10

160 (61.988830566406): select jos_facebook.link from jos_facebook where cat=10

161 (35.04753112793): select jos_google_plus.link from jos_google_plus where cat=10

162 (32.186508178711): select jos_linkedin.link from jos_linkedin where cat=10

163 (303.03001403809): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

164 (!!!!! 2943.0389404297): insert into jos_banners_delta values (14615,'2025-06-25 19:52:03','216.73.216.120','view'),(14202,'2025-06-25 19:52:03','216.73.216.120','view'),(14203,'2025-06-25 19:52:03','216.73.216.120','view')

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