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MRI and Multidimensional Brain Measurements Can Calculate Child’s Age

By MedImaging International staff writers
Posted on 05 Sep 2012

A US team of researchers has developed a multidimensional set of brain measurements that, when combined together, can effectively assess a child’s age with 92% accuracy.

“We have uncovered a ‘developmental clock’ within the brain--a biological signature of maturation that captures age differences quite well regardless of other kinds of differences that exist across individuals,” said first author Timothy T. Brown, PhD, a developmental cognitive neuroscientist in the department of neurosciences at the University of California (UC), San Diego (USA) School of Medicine.

This study of the anatomy of the developing human brain planned for publication in the September 25, 2012, issue of the journal Current Biology, addresses a long-standing scientific query about individual biologic variability in children. The findings revealed that, for specific structural measures, maturational differentiations in the developing human brain are much smaller than was earlier thought--providing the first merged profile of different phases of brain development from ages three to 20 years.

Dr. Brown and lead investigators Terry Jernigan, PhD, professor of cognitive science at UC San Diego and Anders Dale, PhD, UC San Diego professor of neurosciences, collaborated with colleagues nine other major US universities. The study, the first published research from the group’s Pediatric Imaging, Neurocognition, and Genetics Study (PING), was supported by a two-year stimulus grant from the US National Institutes of Health (Bethesda, MD, USA).

The researchers developed a structural set of brain measurements including features of neuroanatomic development such as the shape, size, and tissue properties of various parts of the brain, resulting in what the researchers call a multidimensional phase metric.

The investigators exploited on major developments in structural magnetic resonance imaging (MRI), employing a standardized MRI protocol implemented at nine different institutions, using 12 different MRI scanners. Data were collected in a diverse sample of 885 typically developing children and teens, including information on anatomical brain features known to change over age; for example, measurements of cortical thickness and area, the volume of deep structures, tissue characteristics and signal intensities.

“No individual measurement closely reflects a child’s age across the childhood years, because changes of different kinds cascade dynamically as development progresses. But taken together, the measurements reveal a phenotype that is tightly linked to the child’s chronological age,” said Dr. Jernigan. She added that this collection of multimodal, multisite imaging developments now makes it possible for researchers across institutions to establish large-scale, shared databases.

“Since this multidimensional MRI method is entirely objective, quantitative, and noninvasive, and can powerfully distinguish among different phases of maturity, we hope it might also be useful for the early detection of developmental brain disorders,” said Dr. Brown.

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63 (360.01205444336): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

64 (44.107437133789): select jos_twitters.link from jos_twitters where cat=10

65 (28.848648071289): select jos_facebook.link from jos_facebook where cat=10

66 (30.040740966797): select jos_google_plus.link from jos_google_plus where cat=10

67 (29.087066650391): select jos_linkedin.link from jos_linkedin where cat=10

68 (49.114227294922): SELECT fid FROM jos_deeppockets WHERE id=294742400 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294742400 AND published='1' LIMIT 1

69 (41.007995605469): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

70 (339.03121948242): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294742400 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (222.92137145996): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294742400 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (37.908554077148): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (54.121017456055): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (29.802322387695): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (63.180923461914): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (45.061111450195): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294742400 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (31.948089599609): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294742400 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (36.001205444336): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (55.074691772461): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (72.956085205078): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (72.002410888672): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294742400 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294742400 AND published='1' LIMIT 1

105 (56.028366088867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294742400 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294742400 AND published='1' LIMIT 1

106 (51.021575927734): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294742400 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (46.014785766602): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294742400 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (70.095062255859): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294742400 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294742400 AND published='1' LIMIT 1

109 (51.021575927734): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294742400 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294742400 AND published='1' LIMIT 1

110 (46.014785766602): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294742400 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (451.08795166016): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294742400 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (675.20141601562): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (465.15464782715): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (91.791152954102): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294742400 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294742400 AND published='1' LIMIT 1

115 (117.06352233887): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294742400 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294742400 AND published='1' LIMIT 1

116 (91.075897216797): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294742400 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294742400 AND published='1' LIMIT 1

117 (51.975250244141): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294742400 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294742400 AND published='1' LIMIT 1

118 (55.789947509766): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294742400 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294742400 AND published='1' LIMIT 1

119 (51.021575927734): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294742400 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294742400 AND published='1' LIMIT 1

120 (55.074691772461): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294742400 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294742400 AND published='1' LIMIT 1

121 (42.915344238281): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294742400 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294742400 AND published='1' LIMIT 1

122 (384.09233093262): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 22078.037261963): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (558.85314941406): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294742400 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294742400 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 7325.8876800537): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (89.883804321289): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (284.91020202637): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (51.975250244141): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (200.03318786621): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (37.908554077148): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (229.1202545166): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (42.915344238281): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (230.07392883301): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (44.822692871094): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (439.16702270508): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294742400 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (349.99847412109): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294742400 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (250.81634521484): SELECT name FROM jos_deeppockets WHERE id=212

138 (32.901763916016): SELECT name FROM jos_deeppockets WHERE id=212

139 (530.00450134277): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (472.06878662109): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (69.141387939453): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294742400 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294742400 AND published='1' LIMIT 1

142 (43.869018554688): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294742400 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294742400 AND published='1' LIMIT 1

143 (!!!!! 8147.0012664795): TRUNCATE TABLE jos_trademed_module

144 (92.029571533203): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294742400 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (54.121017456055): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294742400 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (870.94306945801): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294742400 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (61.988830566406): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294742400 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (90.122222900391): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294742400 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294742400 AND published='1' LIMIT 1

149 (88.930130004883): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294742400 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294742400 AND published='1' LIMIT 1

150 (!!!!! 1102.9243469238): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (49.114227294922): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294742400 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294742400 AND published='1' LIMIT 1

152 (41.961669921875): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294742400 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294742400 AND published='1' LIMIT 1

153 (38.862228393555): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294742400 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294742400 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (33.855438232422): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

155 (31.948089599609): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

156 (35.04753112793): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (68.902969360352): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294742400 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294742400 AND published='1' LIMIT 1

158 (45.061111450195): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294742400 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294742400 AND published='1' LIMIT 1

159 (122.0703125): select jos_twitters.link from jos_twitters where cat=10

160 (35.04753112793): select jos_facebook.link from jos_facebook where cat=10

161 (33.855438232422): select jos_google_plus.link from jos_google_plus where cat=10

162 (31.948089599609): select jos_linkedin.link from jos_linkedin where cat=10

163 (291.10908508301): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

164 (946.99859619141): insert into jos_banners_delta values (14615,'2025-06-26 04:53:22','216.73.216.249','view'),(14202,'2025-06-26 04:53:22','216.73.216.249','view'),(14203,'2025-06-26 04:53:22','216.73.216.249','view')

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