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AAPM 2025 - 67th Annual Meeting & Exhibition of the American Association of Physicists in Medicine

MRI, Neuropsychologic Tests Best Predicting Alzheimer’s Disease in Older Patients

By MedImaging International staff writers
Posted on 18 Apr 2012

Dutch investigators have demonstrated that in most elderly patients, invasive and expensive techniques, such as lumbar puncture and positron emission tomography (PET) scanning, are not useful in confirming the diagnosis of Alzheimer’s disease (AD).

The investigators came to this conclusion after analysis of data from the Alzheimer’s Disease Neuroimaging Initiative (ADNI), a large collaborative research project of medical centers in the United States and Canada. The researchers, from the University of Amsterdam (The Netherlands), divided the ADNI sample into two halves, a younger (< 75 years) and an older half (> 74 years). They showed that the cerebral spinal fluid (CSF) biomarkers (amyloid and tau), and fluorodeoxyglucose (FDG)- PET, are beneficial screening tools in the younger but not in the older patients.

In the older patients, MRI scans and neuropsychologic tests appeared to provide useful information, but CSF biomarkers and FDG-PET did not. The latter two techniques are informative only in younger patients. MRI scans and cognitive tests are not only helpful in differentiating patients who are already suffering from dementia from those who are not, but also in predicting who among older mild cognitive impairment (MCI) patients will progress to dementia within a few years. Predictions based on CSF biomarkers may turn out to be accurate in the longer term (5 or 10 years), in patients who live that long and become demented.

“But this long-term prediction is not what doctors, patients and families really need,” noted Willem A. van Gool, professor of neurology at the University of Amsterdam. “They want to know the causes of the symptoms, which made them seek help at a memory clinic, and they want to know what the prognosis is in a shorter time frame.”

From a theoretic point of view these results underscore that dementia in the older elderly is not exactly the same as Alzheimer’s disease in younger patients. It is in all probability a combination of disease processes. At older ages, vascular brain damage and degenerative processes other than amyloid accumulation, such as sclerosis of the hippocampus, are probably significant contributors to the dementia syndrome. “At any rate,” Prof. Van Gool said, “research findings stemming from relatively young patient samples cannot readily be extrapolated to the vast majority of older dementia patients. In older persons with dementia the causes are more complex than mere amyloid-beta accumulation, and researchers have to address this complexity.”

Dr. Ben Schmand, professor of clinical neuropsychology at the University of Amsterdam, cautioned a practical approach for clinicians. “In MCI patients,” he said, “particularly in older patients, it is not sufficient to base a diagnosis solely on a brief memory test, an MRI scan, and a lumbar puncture. Generally, a more thorough clinical evaluation will be necessary Cerebrospinal fluid biomarkers and PET scanning remain informative in relatively young patients.”

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62 (540.01808166504): SELECT fid FROM jos_deeppockets WHERE id=294740253 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294740253 AND published='1' LIMIT 1

63 (291.10908508301): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

64 (84.877014160156): select jos_twitters.link from jos_twitters where cat=10

65 (46.014785766602): select jos_facebook.link from jos_facebook where cat=10

66 (41.961669921875): select jos_google_plus.link from jos_google_plus where cat=10

67 (41.961669921875): select jos_linkedin.link from jos_linkedin where cat=10

68 (49.114227294922): SELECT fid FROM jos_deeppockets WHERE id=294740253 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294740253 AND published='1' LIMIT 1

69 (36.001205444336): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

70 (318.05038452148): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294740253 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (249.86267089844): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294740253 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (53.167343139648): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (52.928924560547): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (68.902969360352): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (74.863433837891): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294740253 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (33.855438232422): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294740253 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (37.193298339844): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (63.896179199219): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (43.869018554688): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (29.802322387695): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (77.009201049805): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (39.815902709961): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (75.817108154297): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740253 AND published='1' LIMIT 1

105 (58.889389038086): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740253 AND published='1' LIMIT 1

106 (67.949295043945): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294740253 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (53.882598876953): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294740253 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (72.002410888672): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740253 AND published='1' LIMIT 1

109 (44.107437133789): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740253 AND published='1' LIMIT 1

110 (49.114227294922): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294740253 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (612.97416687012): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294740253 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (689.98336791992): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (431.06079101562): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (85.830688476562): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740253 AND published='1' LIMIT 1

115 (103.95050048828): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740253 AND published='1' LIMIT 1

116 (128.98445129395): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740253 AND published='1' LIMIT 1

117 (52.928924560547): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740253 AND published='1' LIMIT 1

118 (61.03515625): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740253 AND published='1' LIMIT 1

119 (38.862228393555): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740253 AND published='1' LIMIT 1

120 (48.87580871582): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740253 AND published='1' LIMIT 1

121 (36.001205444336): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740253 AND published='1' LIMIT 1

122 (287.05596923828): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 21621.227264404): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (576.01928710938): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294740253 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294740253 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 8271.9326019287): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (77.962875366211): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (317.09671020508): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (43.153762817383): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (264.88304138184): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (42.915344238281): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (236.98806762695): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (34.809112548828): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (204.08630371094): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (34.093856811523): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (586.98654174805): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740253 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (447.98851013184): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740253 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (297.06954956055): SELECT name FROM jos_deeppockets WHERE id=212

138 (55.074691772461): SELECT name FROM jos_deeppockets WHERE id=212

139 (799.17907714844): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (777.00614929199): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (92.029571533203): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740253 AND published='1' LIMIT 1

142 (51.021575927734): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740253 AND published='1' LIMIT 1

143 (!!!!! 10728.83605957): TRUNCATE TABLE jos_trademed_module

144 (123.02398681641): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294740253 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (61.03515625): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294740253 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (562.90626525879): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740253 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (74.863433837891): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740253 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (70.095062255859): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740253 AND published='1' LIMIT 1

149 (46.968460083008): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740253 AND published='1' LIMIT 1

150 (!!!!! 1250.9822845459): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (97.036361694336): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740253 AND published='1' LIMIT 1

152 (72.956085205078): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740253 AND published='1' LIMIT 1

153 (61.03515625): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294740253 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294740253 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (37.908554077148): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

155 (44.107437133789): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

156 (52.928924560547): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (84.161758422852): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740253 AND published='1' LIMIT 1

158 (65.088272094727): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294740253 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294740253 AND published='1' LIMIT 1

159 (121.11663818359): select jos_twitters.link from jos_twitters where cat=10

160 (60.081481933594): select jos_facebook.link from jos_facebook where cat=10

161 (48.87580871582): select jos_google_plus.link from jos_google_plus where cat=10

162 (44.107437133789): select jos_linkedin.link from jos_linkedin where cat=10

163 (343.08433532715): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

164 (!!!!! 4073.1430053711): insert into jos_banners_delta values (14615,'2025-06-26 08:09:02','216.73.216.249','view'),(14202,'2025-06-26 08:09:02','216.73.216.249','view'),(14203,'2025-06-26 08:09:02','216.73.216.249','view')

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