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Brain, Eye Abnormalities in Astronauts Caused by Long-Term Space Travel

By MedImaging International staff writers
Posted on 28 Mar 2012

Magnetic resonance imaging (MRI) of the eyes and brains of 27 astronauts who have spent prolonged periods of time in space demonstrated optical abnormalities similar to those that can occur in intracranial hypertension of unknown cause, a potentially serious disorder in which pressure builds within the skull.

A retrospective analysis of the MRI data was published online March 13, 2012, in the journal Radiology. Researchers performed MRI scanning and analyzed the data on the 27 astronauts, each of whom were exposed to microgravity, or zero gravity, for an average of 108 days while on space shuttle missions and/or the International Space Station (ISS), a habitable research facility that has been orbiting the earth since 1998. Eight of the 27 astronauts underwent a second MRI exam after a second space mission that lasted an average of 39 days.

“The MRI findings revealed various combinations of abnormalities following both short- and long-term cumulative exposure to microgravity also seen with idiopathic intracranial hypertension,” said Larry A. Kramer, MD, professor of diagnostic and interventional imaging at the University of Texas Medical School (Houston, USA). “These changes that occur during exposure to microgravity may help scientists to better understand the mechanisms responsible for intracranial hypertension in non-space-traveling patients.”

Among astronauts with more than 30 days of cumulative lifetime exposure to microgravity, findings included expansion of the cerebral spinal fluid space surrounding the optic nerve in nine of the 27 (33%) astronauts, flattening of the rear of the eyeball in six (22%), bulging of the optic nerve in four (15%), and changes in the pituitary gland and its connection to the brain in three (11%) of the astronauts. The pituitary gland secretes and stores hormones that regulate a variety of significant body functions.

The same sorts of abnormalities are observed in cases of intracranial hypertension where no cause can be found for increased pressure around the brain. The pressure causes swelling of the juncture between the optic nerve and the eyeball, which can result in visual impairment.

Bone mineral loss and muscle atrophy are some of the recognized effects of zero gravity on astronauts. With the onset of longer excursions in space afforded by the ISS, visual changes have also been noted and are now being evaluated. “Microgravity-induced intracranial hypertension represents a hypothetical risk factor and a potential limitation to long-duration space travel,” Dr. Kramer said.

William J. Tarver, MD, MPH, chief of flight medicine clinic at the US National Aeronautics and Space Administration (NASA) /Johnson Space Center (Houston, TX, USA), reported that the agency has observed changes in vision in some ISS astronauts, the origin of which is not yet fully determined. No astronauts have been considered ineligible for space flight duties as a result of the findings, which he said are suspicious but not conclusive of intracranial hypertension. “NASA has placed this problem high on its list of human risks, has initiated a comprehensive program to study its mechanisms and implications, and will continue to closely monitor the situation,” Dr. Tarver said.

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61 (859.02214050293): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

62 (580.0724029541): SELECT fid FROM jos_deeppockets WHERE id=294739968 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294739968 AND published='1' LIMIT 1

63 (159.02519226074): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

64 (308.99047851562): select jos_twitters.link from jos_twitters where cat=10

65 (278.94973754883): select jos_facebook.link from jos_facebook where cat=10

66 (156.16416931152): select jos_google_plus.link from jos_google_plus where cat=10

67 (31.948089599609): select jos_linkedin.link from jos_linkedin where cat=10

68 (144.95849609375): SELECT fid FROM jos_deeppockets WHERE id=294739968 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294739968 AND published='1' LIMIT 1

69 (161.17095947266): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

70 (605.10635375977): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294739968 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (251.05476379395): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294739968 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (162.12463378906): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (406.98051452637): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (47.206878662109): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (223.15979003906): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (29.802322387695): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (272.98927307129): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (218.86825561523): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (42.200088500977): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (459.90943908691): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294739968 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (390.05279541016): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294739968 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (123.97766113281): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (335.2165222168): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (88.214874267578): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (104.90417480469): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (163.07830810547): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (204.08630371094): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (92.983245849609): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (101.08947753906): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (113.01040649414): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (93.936920166016): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (118.01719665527): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (152.1110534668): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (74.863433837891): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (70.095062255859): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (80.82389831543): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (150.91896057129): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739968 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739968 AND published='1' LIMIT 1

105 (153.0647277832): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739968 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739968 AND published='1' LIMIT 1

106 (124.93133544922): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294739968 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (117.06352233887): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294739968 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (586.98654174805): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739968 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739968 AND published='1' LIMIT 1

109 (161.88621520996): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739968 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739968 AND published='1' LIMIT 1

110 (157.11784362793): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294739968 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (597.95379638672): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294739968 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (635.14709472656): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (476.12190246582): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (108.95729064941): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739968 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739968 AND published='1' LIMIT 1

115 (58.174133300781): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739968 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739968 AND published='1' LIMIT 1

116 (63.896179199219): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739968 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739968 AND published='1' LIMIT 1

117 (51.975250244141): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739968 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739968 AND published='1' LIMIT 1

118 (112.05673217773): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739968 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739968 AND published='1' LIMIT 1

119 (50.067901611328): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739968 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739968 AND published='1' LIMIT 1

120 (51.975250244141): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739968 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739968 AND published='1' LIMIT 1

121 (39.100646972656): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739968 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739968 AND published='1' LIMIT 1

122 (241.99485778809): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 53569.078445435): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (955.82008361816): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294739968 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294739968 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (134.94491577148): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (65.803527832031): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (66.995620727539): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (45.061111450195): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (81.062316894531): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (44.107437133789): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (67.949295043945): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (52.928924560547): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (49.114227294922): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (40.054321289062): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (447.98851013184): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739968 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (414.13307189941): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739968 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (39.100646972656): SELECT name FROM jos_deeppockets WHERE id=212

138 (30.040740966797): SELECT name FROM jos_deeppockets WHERE id=212

139 (810.86158752441): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (848.05488586426): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (140.90538024902): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739968 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739968 AND published='1' LIMIT 1

142 (57.93571472168): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739968 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739968 AND published='1' LIMIT 1

143 (!!!!! 9607.7919006348): TRUNCATE TABLE jos_trademed_module

144 (110.14938354492): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294739968 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (58.889389038086): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294739968 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (573.15826416016): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739968 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (85.830688476562): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739968 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (93.936920166016): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739968 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739968 AND published='1' LIMIT 1

149 (66.041946411133): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739968 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739968 AND published='1' LIMIT 1

150 (!!!!! 1502.0370483398): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (92.029571533203): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739968 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739968 AND published='1' LIMIT 1

152 (59.127807617188): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739968 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739968 AND published='1' LIMIT 1

153 (85.830688476562): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294739968 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294739968 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (42.200088500977): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

155 (41.007995605469): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

156 (61.988830566406): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (138.99803161621): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739968 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739968 AND published='1' LIMIT 1

158 (68.902969360352): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294739968 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294739968 AND published='1' LIMIT 1

159 (56.028366088867): select jos_twitters.link from jos_twitters where cat=10

160 (36.954879760742): select jos_facebook.link from jos_facebook where cat=10

161 (36.954879760742): select jos_google_plus.link from jos_google_plus where cat=10

162 (37.908554077148): select jos_linkedin.link from jos_linkedin where cat=10

163 (401.97372436523): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

164 (!!!!! 1857.9959869385): insert into jos_banners_delta values (14615,'2025-06-26 08:35:08','216.73.216.249','view'),(14202,'2025-06-26 08:35:08','216.73.216.249','view'),(14203,'2025-06-26 08:35:08','216.73.216.249','view')

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