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AAPM 2025 - 67th Annual Meeting & Exhibition of the American Association of Physicists in Medicine

Pain Meter in Development Using fMRI Scans and Computer Algorithms

By MedImaging International staff writers
Posted on 28 Sep 2011

Researchers have taken the first steps toward devising a diagnostic tool that could eliminate a major obstacle in pain medicine--the dependency on self-reporting to measure the presence or absence of pain. The new tool would use patterns of brain activity to give an objective physiologic evaluation of whether someone is in pain.

The scientists, from the Stanford University School of Medicine (Stanford, CA, USA) utilized functional magnetic resonance imaging (fMRI) scans of the brain combined with advanced computer algorithms to accurately predict thermal pain 81% of the time in healthy study participants, according to a study published September 13, 2011, in the online journal PLoS ONE. “People have been looking for a pain detector for a very long time,” said Sean Mackey, MD, PhD, chief of the division of pain management and associate professor of anesthesiology. “We’re hopeful we can eventually use this technology for better detection and better treatment of chronic pain.”

Researchers emphasized that future studies are needed to determine whether these methods will work to measure various kinds of pain, such as chronic pain, and whether they can distinguish accurately between pain and other emotionally arousing states, such as anxiety or depression. “A key thing to remember is that this approach objectively measured thermal pain in a controlled lab setting,” Dr. Mackey said. “We should take care not to extrapolate these findings to say we can measure and detect pain in all circumstances.”

The need for a better way to measure pain objectively instead of relying on the current technique of self-reporting has long been recognized, but the highly subjective nature of pain has made this an elusive goal.

Advances in neuroimaging techniques have reinvigorated the debate over whether it might be possible to measure pain physiologically, and in fact, led to this current study. “We rely on patient self-reporting for pain, and that remains the gold standard,” commented Dr. Mackey, senior author of the study. “That’s what I, as a physician, rely on when I take care of a patient with chronic pain. But there are a large number of patients, particularly among the very young and the very old, who can’t communicate their pain levels. Wouldn’t it be great if we had a technique that could measure pain physiologically?”

A study released by the Institute of Medicine in June 2011 reported that more than 100 million Americans suffer chronic pain, costing around US$600 billion each year in medical expenses, and lost productivity. (Dr. Mackey was a member of the committee that produced the report.) Moreover, it found that cultural bias against chronic pain sufferers as being weak or even worse--they are often perceived as lying about their pain--complicates the delivery of appropriate treatment. Similar biases crop up in the legal field, with hundreds of thousands of cases each year that hinge on the existence of pain, according to Stanford law professor Hank Greely, an expert on the legal, ethical and social issues surrounding the biosciences. “A robust, accurate way to determine whether someone is in pain or not would be a godsend for the legal system,” said Prof. Greely, who did not participate in the study.

The idea for this study germinated at a 2009 Stanford Law School event organized by Prof. Greely that brought together neuroscientists and legal scholars to discuss how the neuroimaging of pain could be used and abused in the legal system. Dr. Mackey and two of his lab assistants attended. “At the end of the symposium, there was discussion about the challenges of creating a ‘pain-o-meter.’ I discussed hypothetically how we could do this in the future,” Dr. Mackey said. “These two young scientists in my lab came up to me after and said, ‘We think we can do this. We would like to try.’ I was skeptical.”

The two scientists--Neil Chatterjee, currently a MD/PhD student at Northwestern University (Evanston, IL, USA) , and first author of the study, Justin Brown, PhD, now an assistant professor of biology at Simpson College (Indianola, IA, USA) --came up with the concept in a discussion after the symposium.

“It was very much on a whim,” said coauthor Mr. Chatterjee. “We thought, maybe we can’t make the perfect tool, but has anyone ever really tried doing this on a very, very basic level? It turned out to be surprisingly simple to do this.”

Researchers took eight individuals, and placed them in the brain-scanning machine. A heat probe was then applied to their forearms, causing moderate pain. The brain patterns both with and without pain were then recorded and interpreted by advanced computer algorithms to create a model of what pain looks like. The process was repeated with a second group of eight subjects.

The plan was to train a linear support vector machine--a computer algorithm invented in 1995-- on one set of individuals, and then use that computer model to classify pain accurately in a completely new set of individuals.

The computer was then asked to consider the brain scans of eight new subjects and determine whether they had thermal pain. “We asked the computer to come up with what it thinks pain looks like,” Mr. Chatterjee said. “Then we could measure how well the computer did. And it did amazingly well. The computer was successful 81% of the time. I was definitely surprised.”

Related Links:
Stanford University School of Medicine
Northwestern University
Simpson College

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55 (91.075897216797): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294737327 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

56 (477.07557678223): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294737327 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

57 (!!!!! 1152.0385742188): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294737327 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294737327 AND published='1' LIMIT 1

58 (66.995620727539): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294737327 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294737327 AND published='1' LIMIT 1

59 (!!!!! 2702.9514312744): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294737327 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294737327 AND published='1' LIMIT 1

60 (112.05673217773): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294737327 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294737327 AND published='1' LIMIT 1

61 (255.10787963867): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

62 (653.02848815918): SELECT fid FROM jos_deeppockets WHERE id=294737327 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294737327 AND published='1' LIMIT 1

63 (651.12113952637): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

64 (296.83113098145): select jos_twitters.link from jos_twitters where cat=10

65 (211.00044250488): select jos_facebook.link from jos_facebook where cat=10

66 (!!!!! 3676.8913269043): select jos_google_plus.link from jos_google_plus where cat=10

67 (192.88063049316): select jos_linkedin.link from jos_linkedin where cat=10

68 (432.01446533203): SELECT fid FROM jos_deeppockets WHERE id=294737327 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294737327 AND published='1' LIMIT 1

69 (231.02760314941): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

70 (594.8543548584): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294737327 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (495.19538879395): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294737327 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (41.961669921875): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (490.18859863281): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (52.928924560547): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (162.12463378906): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (165.93933105469): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (182.8670501709): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (44.107437133789): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (305.8910369873): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (42.915344238281): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (39.815902709961): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (38.14697265625): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (246.04797363281): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (187.15858459473): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (645.87593078613): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294737327 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (921.01097106934): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294737327 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (294.92378234863): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (!!!!! 1303.9112091064): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (228.1665802002): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (138.0443572998): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (51.975250244141): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (52.928924560547): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (41.007995605469): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (68.902969360352): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (261.78359985352): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (218.86825561523): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (45.061111450195): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (98.943710327148): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (319.00405883789): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (73.909759521484): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (133.03756713867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294737327 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294737327 AND published='1' LIMIT 1

105 (81.777572631836): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294737327 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294737327 AND published='1' LIMIT 1

106 (125.88500976562): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294737327 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (72.956085205078): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294737327 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (678.77769470215): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294737327 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294737327 AND published='1' LIMIT 1

109 (165.93933105469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294737327 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294737327 AND published='1' LIMIT 1

110 (97.036361694336): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294737327 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (!!!!! 1766.9200897217): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294737327 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (669.00253295898): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (456.09474182129): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (103.95050048828): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294737327 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294737327 AND published='1' LIMIT 1

115 (66.995620727539): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294737327 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294737327 AND published='1' LIMIT 1

116 (72.956085205078): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294737327 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294737327 AND published='1' LIMIT 1

117 (51.021575927734): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294737327 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294737327 AND published='1' LIMIT 1

118 (114.20249938965): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294737327 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294737327 AND published='1' LIMIT 1

119 (58.174133300781): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294737327 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294737327 AND published='1' LIMIT 1

120 (67.949295043945): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294737327 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294737327 AND published='1' LIMIT 1

121 (77.009201049805): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294737327 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294737327 AND published='1' LIMIT 1

122 (311.13624572754): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 21164.894104004): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (618.93463134766): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294737327 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294737327 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 8065.938949585): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (106.8115234375): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (156.87942504883): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (65.088272094727): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (68.902969360352): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (35.04753112793): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (361.91940307617): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (46.968460083008): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (46.014785766602): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (36.954879760742): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (505.92422485352): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294737327 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (444.17381286621): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294737327 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (294.92378234863): SELECT name FROM jos_deeppockets WHERE id=212

138 (46.968460083008): SELECT name FROM jos_deeppockets WHERE id=212

139 (681.87713623047): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (551.93901062012): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (123.97766113281): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294737327 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294737327 AND published='1' LIMIT 1

142 (52.213668823242): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294737327 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294737327 AND published='1' LIMIT 1

143 (!!!!! 8893.0130004883): TRUNCATE TABLE jos_trademed_module

144 (117.06352233887): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294737327 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (80.82389831543): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294737327 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (656.8431854248): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294737327 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (61.03515625): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294737327 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (90.122222900391): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294737327 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294737327 AND published='1' LIMIT 1

149 (59.843063354492): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294737327 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294737327 AND published='1' LIMIT 1

150 (!!!!! 1432.8956604004): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (76.055526733398): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294737327 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294737327 AND published='1' LIMIT 1

152 (75.101852416992): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294737327 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294737327 AND published='1' LIMIT 1

153 (39.100646972656): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294737327 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294737327 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (36.954879760742): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

155 (41.007995605469): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

156 (39.100646972656): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (217.91458129883): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294737327 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294737327 AND published='1' LIMIT 1

158 (298.02322387695): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294737327 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294737327 AND published='1' LIMIT 1

159 (51.975250244141): select jos_twitters.link from jos_twitters where cat=10

160 (36.001205444336): select jos_facebook.link from jos_facebook where cat=10

161 (70.095062255859): select jos_google_plus.link from jos_google_plus where cat=10

162 (37.908554077148): select jos_linkedin.link from jos_linkedin where cat=10

163 (328.06396484375): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

164 (!!!!! 1092.9107666016): insert into jos_banners_delta values (14615,'2025-06-27 00:00:49','216.73.216.249','view'),(14202,'2025-06-27 00:00:49','216.73.216.249','view'),(14203,'2025-06-27 00:00:49','216.73.216.249','view')

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