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AAPM 2025 - 67th Annual Meeting & Exhibition of the American Association of Physicists in Medicine

Scientists Build $8.6 Million Imaging Suite to Speed Epidemics Diagnosis

By MedImaging International staff writers
Posted on 25 Aug 2011

A collaboration effort has been initiated to develop new imaging technology that could be used to help identify the beginning--and cause--of an epidemic.

The partnership is between the Methodist Hospital Research Institute (Houston, TX, USA) and Philips Healthcare (Best, The Netherlands). King Li, MD, radiology chair and the project’s leader, and other Methodist scientists will utilize an US$8.6 million imaging suite that includes an magnetic resonance imaging (MRI), a positron emission tomography-computed tomography (PET-CT) scanner, a single photon emission computed tomography-computed tomography (SPECT-CT) scanner, and an X-ray C-arm to study patterns of tissue damage and metabolic disarray caused by different infectious disease agents--without exposing the devices or suite rooms to the infectious agents. The suite is scheduled to be completed later in August 2011.

“The ability to have imaging suites that can handle high level infectious agents allows us to be more prepared in the community for these types of events and, more importantly, allows us to study ways to deal with their consequences,” Dr. Li said.

Airtight containment vessels make it possible for samples and infected research models to be imaged without posing risks of exposure to patients, researchers, or staff. Sophisticated technology also allows for rapid image scanning, so that time series imagery is possible. “No one can do longitudinal imaging studies anywhere at the moment,” said Ed Jones, vice president of operations for The Methodist Hospital Research Institute. “Researchers at Methodist will be able to do live imaging studies that give them crucial information about how and where infections are progressing. This is what can happen when the best scientists and engineers from academia and industry become partners in advancing the state of the art in medical technology.”

Methodist will be the sole practical test site for the development of the technology.

The purpose of the suite is to study pathogens that require biosafety level 3 (BSL-3) containment. BSL-3 pathogens include the bacteria that cause tuberculosis. “This imaging facility will be the first of its kind,” said James M. Musser, MD, PhD, chair of the department of pathology and laboratory medicine and director of the Center for Molecular and Translational Human Infectious Diseases Research at The Methodist Hospital. “Our facility will permit us to translate critical new discoveries into the clinic, permitting accelerated development of novel diagnostic strategies and assessment of new therapeutic agents and vaccines.”

According to Dr. King Li, the idea that imaging techniques might be used to shield populations from epidemiologic harm is nearly 10 years old. “After 9/11 and the SARS [severe acute respiratory syndrome] outbreak in southeast Asia, the NIH [US National Institutes of Health; Bethesda, MD, USA] wanted to build a BSL-4 imaging suite for studying infectious agents, both natural and bioterrorism-related,” Dr. Li said. “I was at the NIH at the time, and helped design the imaging equipment for that facility.”

Dr. Li’s research with Philips led to two pending imaging patents. A containment vessel will keep the subjects--initially model organisms--isolated from the unexposed space around it. Each vessel, or imaging cell, is accompanied by an external life support device on a transport trolley. The trolley is also used to maneuver the subject into place for imaging.

One of the project’s ultimate goals, Dr. Li reported, is to develop a similar facility that is equipped to diagnose infectious diseases in a large influx of (human) patients. “If the partnership with Philips is successful, The Methodist Hospital Research Institute can take the next steps toward creating the only clinic in the world expressly designed to image patients with infectious agents, such as multidrug-resistant TB,” Dr. Li said. “This will allow for medical centers in the world to be more prepared for emerging diseases and bioterrorism.”

The specific systems provided by Philips are the Ingenia 3T, Gemini TF 64, Precedence 16, and Veradius mobile C-arm.

Related Links:
Methodist Hospital Research Institute
Philips Healthcare

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58 (86.069107055664): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736759 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736759 AND published='1' LIMIT 1

59 (187.87384033203): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736759 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736759 AND published='1' LIMIT 1

60 (87.976455688477): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736759 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736759 AND published='1' LIMIT 1

61 (107.76519775391): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

62 (600.81481933594): SELECT fid FROM jos_deeppockets WHERE id=294736759 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294736759 AND published='1' LIMIT 1

63 (56.028366088867): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

64 (61.03515625): select jos_twitters.link from jos_twitters where cat=10

65 (82.015991210938): select jos_facebook.link from jos_facebook where cat=10

66 (45.061111450195): select jos_google_plus.link from jos_google_plus where cat=10

67 (36.954879760742): select jos_linkedin.link from jos_linkedin where cat=10

68 (59.843063354492): SELECT fid FROM jos_deeppockets WHERE id=294736759 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294736759 AND published='1' LIMIT 1

69 (46.968460083008): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

70 (471.11511230469): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294736759 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (365.01884460449): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294736759 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (60.081481933594): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (76.055526733398): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (51.021575927734): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (50.067901611328): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (39.815902709961): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (40.054321289062): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (44.107437133789): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294736759 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (30.040740966797): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294736759 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (43.153762817383): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (48.87580871582): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (33.855438232422): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (41.007995605469): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (95.129013061523): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736759 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736759 AND published='1' LIMIT 1

105 (73.909759521484): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736759 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736759 AND published='1' LIMIT 1

106 (53.882598876953): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294736759 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (46.968460083008): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294736759 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (76.055526733398): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736759 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736759 AND published='1' LIMIT 1

109 (54.121017456055): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736759 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736759 AND published='1' LIMIT 1

110 (51.021575927734): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294736759 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (519.0372467041): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294736759 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (678.06243896484): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (365.9725189209): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (74.863433837891): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736759 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736759 AND published='1' LIMIT 1

115 (60.081481933594): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736759 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736759 AND published='1' LIMIT 1

116 (47.922134399414): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736759 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736759 AND published='1' LIMIT 1

117 (36.954879760742): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736759 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736759 AND published='1' LIMIT 1

118 (53.167343139648): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736759 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736759 AND published='1' LIMIT 1

119 (77.962875366211): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736759 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736759 AND published='1' LIMIT 1

120 (41.007995605469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736759 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736759 AND published='1' LIMIT 1

121 (36.954879760742): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736759 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736759 AND published='1' LIMIT 1

122 (299.93057250977): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 46283.960342407): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (487.08915710449): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294736759 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294736759 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 15016.078948975): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (68.902969360352): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (37.193298339844): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (29.087066650391): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (37.908554077148): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (29.087066650391): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (293.97010803223): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (92.983245849609): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (31.948089599609): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (28.133392333984): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (413.89465332031): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736759 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (474.92980957031): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736759 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (64.849853515625): SELECT name FROM jos_deeppockets WHERE id=212

138 (27.179718017578): SELECT name FROM jos_deeppockets WHERE id=212

139 (534.0576171875): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (559.09156799316): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (109.91096496582): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736759 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736759 AND published='1' LIMIT 1

142 (46.968460083008): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736759 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736759 AND published='1' LIMIT 1

143 (!!!!! 5975.0080108643): TRUNCATE TABLE jos_trademed_module

144 (!!!!! 3917.2172546387): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294736759 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (108.95729064941): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294736759 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (375.03242492676): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736759 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (165.93933105469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736759 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (65.088272094727): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736759 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736759 AND published='1' LIMIT 1

149 (42.915344238281): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736759 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736759 AND published='1' LIMIT 1

150 (!!!!! 1088.8576507568): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (57.93571472168): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736759 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736759 AND published='1' LIMIT 1

152 (42.915344238281): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736759 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736759 AND published='1' LIMIT 1

153 (41.961669921875): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294736759 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294736759 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (40.054321289062): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

155 (29.802322387695): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

156 (29.087066650391): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (!!!!! 3111.1240386963): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736759 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736759 AND published='1' LIMIT 1

158 (65.088272094727): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294736759 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294736759 AND published='1' LIMIT 1

159 (47.922134399414): select jos_twitters.link from jos_twitters where cat=10

160 (28.133392333984): select jos_facebook.link from jos_facebook where cat=10

161 (27.179718017578): select jos_google_plus.link from jos_google_plus where cat=10

162 (25.98762512207): select jos_linkedin.link from jos_linkedin where cat=10

163 (324.01084899902): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

164 (835.18028259277): insert into jos_banners_delta values (14615,'2025-06-22 02:54:21','216.73.216.120','view'),(14202,'2025-06-22 02:54:21','216.73.216.120','view'),(14203,'2025-06-22 02:54:21','216.73.216.120','view')

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