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MR Scans Reveal Brain May Age Faster in People Whose Hearts Pump Less Blood

By MedImaging International staff writers
Posted on 02 Sep 2010

In a new study, individuals whose hearts pumped less blood had brains that appeared older than the brains of those whose hearts pumped more blood. Decreased cardiac index, the amount of blood that pumps from the heart in relation to an individual's body size, was linked to decreased brain volume using magnetic resonance imaging (MRI).

Researchers observed the link even in those participants who did not have cardiovascular disease, such as heart failure or coronary heart disease. As the brain ages, it starts to atrophy (shrink) and has less volume. The decrease in brain volume is considered a sign of brain aging. More severe brain atrophy occurs in those with dementia, such as Alzheimer's disease.

"The results are interesting in that they suggest cardiac index and brain health are related,” said Angela L. Jefferson, Ph.D., the study's lead author and associate professor of neurology at the Boston University School of Medicine (MA, USA). "The association cannot be attributed to cardiovascular disease because the relationship also was seen when we removed those participants with known cardiovascular disease from our analyses.”

In the observational analyses, which cannot establish cause and effect, researchers examined brain and heart MRI information on 1,504 participants of the decades-long Framingham Offspring Cohort who did not have a history of stroke, transient ischemic attack, or dementia. Participants were 34 to 84 years old and 54% were women.

Researchers measured cardiac output using MRI and normalized the data for each participant's body surface area. Brain volume was evaluated using MRI scanning. Participants were divided into three groups based on cardiac index values. The participants who had the lowest cardiac index, or the least amount of blood pumping from the heart for their body size, demonstrated nearly two years more brain aging than the people with the highest cardiac index. The participants in the middle cardiac index group, who had low but still normal levels of blood pumping from the heart, also showed almost two years more brain aging than the people with the highest (or healthiest) cardiac index.

"We expected an association between the lowest levels of cardiac index and smaller brain volumes, but we were surprised to find people on the lower end of normal cardiac index also have smaller brain volumes when compared to people with very health cardiac index,” Dr. Jefferson said.

Because only 7% of all participants in the study had heart disease, Dr. Jefferson and her colleagues also did not expect 30% of participants would have low cardiac index. "These participants are not sick people. A very small number have heart disease. The observation that nearly a third of the entire sample has low cardiac index and that lower cardiac index is related to smaller brain volume is concerning and requires further study.”

As a group, participants with smaller brain volumes did not demonstrate obvious clinical signs of diminished brain function. "We observed cardiac index is related to structural changes in the brain but not cognitive changes,” Dr. Jefferson noted. "The structural changes may be early evidence that something is wrong. Investigators from Framingham will continue to follow these individuals to see how structural brain changes affect memory and cognitive abilities over time.”

The precise cause for a link between heart function and brain volume is still not well understood, according to Dr. Jefferson. "There are several theories for why reduced cardiac index might affect brain health. For instance, a lower volume of blood pumping from the heart might reduce blood flow to the brain, providing less oxygen and fewer nutrients needed for brain cells. It is too early to dole out health advice based on this one finding but it does suggest that heart and brain health go hand in hand.”

The study's findings were reported in the August 2010 issue of Circulation, the Journal of the American Heart Association.

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59 (154.97207641602): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294730976 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294730976 AND published='1' LIMIT 1

60 (!!!!! 3431.0817718506): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294730976 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294730976 AND published='1' LIMIT 1

61 (147.10426330566): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

62 (661.13471984863): SELECT fid FROM jos_deeppockets WHERE id=294730976 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294730976 AND published='1' LIMIT 1

63 (506.16264343262): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

64 (88.214874267578): select jos_twitters.link from jos_twitters where cat=10

65 (44.107437133789): select jos_facebook.link from jos_facebook where cat=10

66 (41.961669921875): select jos_google_plus.link from jos_google_plus where cat=10

67 (61.03515625): select jos_linkedin.link from jos_linkedin where cat=10

68 (60.081481933594): SELECT fid FROM jos_deeppockets WHERE id=294730976 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294730976 AND published='1' LIMIT 1

69 (56.982040405273): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

70 (369.07196044922): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294730976 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (346.89903259277): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294730976 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (50.067901611328): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (92.983245849609): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (46.014785766602): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (42.915344238281): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (37.193298339844): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (51.975250244141): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (41.007995605469): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (83.208084106445): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294730976 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (42.915344238281): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294730976 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (46.014785766602): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (47.922134399414): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (29.802322387695): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (84.877014160156): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294730976 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294730976 AND published='1' LIMIT 1

105 (42.915344238281): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294730976 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294730976 AND published='1' LIMIT 1

106 (567.91305541992): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294730976 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (55.074691772461): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294730976 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (109.91096496582): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294730976 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294730976 AND published='1' LIMIT 1

109 (47.922134399414): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294730976 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294730976 AND published='1' LIMIT 1

110 (48.87580871582): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294730976 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (557.89947509766): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294730976 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (610.1131439209): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (353.09791564941): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (79.870223999023): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294730976 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294730976 AND published='1' LIMIT 1

115 (50.067901611328): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294730976 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294730976 AND published='1' LIMIT 1

116 (47.206878662109): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294730976 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294730976 AND published='1' LIMIT 1

117 (41.961669921875): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294730976 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294730976 AND published='1' LIMIT 1

118 (45.061111450195): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294730976 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294730976 AND published='1' LIMIT 1

119 (41.961669921875): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294730976 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294730976 AND published='1' LIMIT 1

120 (114.91775512695): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294730976 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294730976 AND published='1' LIMIT 1

121 (44.107437133789): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294730976 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294730976 AND published='1' LIMIT 1

122 (384.80758666992): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 46704.053878784): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (!!!!! 1029.0145874023): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294730976 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294730976 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 24074.792861938): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (72.956085205078): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (61.03515625): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (46.968460083008): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (252.00843811035): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (46.014785766602): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (!!!!! 5173.921585083): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (66.041946411133): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (310.89782714844): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (50.067901611328): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (534.0576171875): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294730976 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (447.98851013184): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294730976 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (284.91020202637): SELECT name FROM jos_deeppockets WHERE id=212

138 (48.160552978516): SELECT name FROM jos_deeppockets WHERE id=212

139 (746.9654083252): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (714.06364440918): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (102.04315185547): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294730976 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294730976 AND published='1' LIMIT 1

142 (72.956085205078): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294730976 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294730976 AND published='1' LIMIT 1

143 (!!!!! 12946.844100952): TRUNCATE TABLE jos_trademed_module

144 (!!!!! 5450.0102996826): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294730976 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (!!!!! 2580.1658630371): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294730976 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (644.92225646973): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294730976 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (109.19570922852): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294730976 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (82.015991210938): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294730976 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294730976 AND published='1' LIMIT 1

149 (61.03515625): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294730976 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294730976 AND published='1' LIMIT 1

150 (!!!!! 1693.9640045166): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (89.883804321289): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294730976 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294730976 AND published='1' LIMIT 1

152 (57.93571472168): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294730976 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294730976 AND published='1' LIMIT 1

153 (47.206878662109): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294730976 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294730976 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (40.054321289062): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

155 (36.001205444336): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

156 (42.915344238281): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (!!!!! 2544.8799133301): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294730976 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294730976 AND published='1' LIMIT 1

158 (741.00494384766): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294730976 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294730976 AND published='1' LIMIT 1

159 (73.909759521484): select jos_twitters.link from jos_twitters where cat=10

160 (34.093856811523): select jos_facebook.link from jos_facebook where cat=10

161 (33.855438232422): select jos_google_plus.link from jos_google_plus where cat=10

162 (32.186508178711): select jos_linkedin.link from jos_linkedin where cat=10

163 (319.9577331543): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

164 (!!!!! 1096.9638824463): insert into jos_banners_delta values (14615,'2025-06-28 02:40:11','216.73.216.249','view'),(14202,'2025-06-28 02:40:11','216.73.216.249','view'),(14203,'2025-06-28 02:40:11','216.73.216.249','view')

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