We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us
GLOBETECH PUBLISHING LLC

Download Mobile App




Hyper-SAGE Technology Boosts Remote MRI Sensitivity

By MedImaging International staff writers
Posted on 02 Nov 2009
A new magnetic resonance imaging (MRI) technique, called hyper-SAGE (signal amplification by gas extraction), has the potential to detect ultra-low concentrations of clinical targets, such as lung and other cancers.

Development of hyper-SAGE technology was led by one of the world's leading authorities on MRI technology, Dr. Alexander Pines, a chemist who holds joint appointments with the Lawrence Berkeley U.S. National Laboratory (Berkeley Lab; Livermore, CA, USA) and the University of California, Berkeley (USA). The key to this technique is xenon gas that has been bombarded with laser light to "hyperpolarize” the spins of its atomic nuclei so that most are pointing in the same direction.

"By detecting the MRI signal of dissolved hyperpolarized xenon after the xenon has been extracted back into the gas phase, we can boost the signal's strength up to 10,000 times,” Dr. Pines said. "It is absolutely amazing because we're looking at pure gas and can reconstruct the whole image of our target. With this degree of sensitivity, Hyper-SAGE becomes a highly promising tool for in vivo diagnostics [IVD] and molecular imaging.”

MRI is a painless and radiation-free means of obtaining high quality three-dimensional (3D) tomographic images of internal tissue and organs. It is particularly valuable for optically opaque samples, such as blood. However, the application of MRI to biomedical samples has been limited by sensitivity issues. For the past three decades, Dr. Pines has led an ongoing effort to find ways of enhancing the sensitivity of MRI and its sister technology, nuclear magnetic resonance (NMR) spectroscopy. Hyper-SAGE, the latest development, represents a significant new advance for both technologies, according to Dr. Xin Zhou, a member of Dr. Pines' research group.

"Hyper-SAGE is a totally novel way to amplify a solvated xenon MRI/NMR signal in that instead of a chemical process, which is what previous signal enhancement techniques relied upon, it is a physical process,” said Dr. Zhou. "Because gas can be physically compressed, the density of information-carrying polarized gas in our detection chamber can be much greater than the density of an information-carrying solution. This means we can detect MRI signals from concentrations of molecules many thousands of times smaller than can be detected with conventional MRI.”

Dr. Zhou is the first author on an article available online in October 2009 in the Proceedings of the [U.S.] National Academy of Sciences (PNAS). The great contradiction about MRI/NMR spectroscopy is that for being two of the most powerful tools available today for studying the chemical composition and structure of a sample, they are based on an incredible weak signal. Both depend upon atomic nuclei that have an unpaired proton or neutron. Such nuclei spin on an axis similar to miniature tops, giving rise to a magnetic moment--meaning the nuclei act like magnets with a north and south pole. When exposed to an external magnetic field, these spinning "bar magnets” attempt to align their axes along the lines of magnetic force. Since the alignment is not exact, the result is a wobbling rotation, or "precession,” that is unique to each type of atom.

If, while exposed to the magnetic field, the precessing nuclei are also hit with a radiofrequency (RF) pulse, they will absorb and reemit energy at specific frequencies according to their rate of precession (NMR). When the RF pulse is combined with magnetic field gradients a spatially encoded signal is produced, which can be detected and translated into three-dimensional images (MRI).

Obtaining an MRI signal from a sample depends upon the spins of its precessing nuclei being polarized so that an excess point either "up” or "down.” MRI's intrinsic weakness stems from the fact that the natural excess of up versus down spins for any typical population of atomic nuclei in a sample is only approximately one in 100,000. For this reason, traditional MRI techniques are designed to detect nuclei that are highly abundant in tissue, typically the protons in water. Moreover, clinicians use contrasting agents to induce detectable changes in the MRI signal from a sample that can reveal the presence of anomalies. However, the sensitivity is usually too low for molecular imaging, which is needed in cancer detection, for example, where the earliest detections generally produce the most favorable outcomes.

Dr. Pines and his research group have developed numerous ways of increasing the sensitivity of MRI technology and expanding its applicability. Earlier research demonstrated that xenon, an inert gas whose nuclei naturally feature a tiny degree of spin polarization, can be hyperpolarized with laser light to produce a population of xenon atoms in which nearly five out of every 10 nuclei--instead of one out of every 100,000--- produce an MRI signal. The investigators also showed that xenon can be incorporated into a biosensor and linked to specific proteins or other biologic molecules to generated spatial images of a chosen molecular or cellular target.

The new technique, Hyper-SAGE, offers other major advantages over conventional MRI/NMR techniques in addition to a signal that is up to 10,000 times stronger than previous signals, according to Dr. Zhou. "Xenon gas has an intrinsically long relaxation time, greater than 45 minutes, which means the signal lasts long enough for us to collect all the encoded information, which in turn can enable us to detect specific targets, such as cancer-related proteins, at micromolar or parts per million concentrations,” he stated. "Also, Hyper-SAGE utilizes remote detection, meaning the signal encoding and detection processes are physically separated and carried out independently. This is a plus for imaging the lung, for example, where the signal of interest would occupy only a small portion of the traditional MRI signal receiver.”

In their PNAS article, Drs. Zhou, Graziani, and Pines describe the successful testing of the Hyper-SAGE technique on a pair of membranes that mimicked the function of the lungs. Hyperpolarized xenon was dissolved in solution in one membrane to mimic inhalation, and was then extracted as a gas for detection from the other membrane to represent exhalation.

Explained Dr. Zhou, "In a clinical setting, a patient would inhale the hyperpolarized xenon gas which would be dissolved in the blood and allowed to flow into the body and brain. The exhaled xenon gas would then be collected and its MRI signal would be detected. Used in combination with a target-specific xenon biomolecular sensor, we should be able to study the gas-exchange in the lung and detect cancerous cells at their earliest stage of development.”

Berkeley Lab is a U.S. Department of Energy national laboratory located in Berkeley, California. It conducts unclassified scientific research for Department of Energy's (DOE) Office of Science and is managed by the University of California.

Related Links:
Lawrence Berkeley National Laboratory
University of California, Berkeley


Gold Member
Ultrasound System
FUTUS LE
Gold Member
Electrode Solution and Skin Prep
Signaspray
Web-Based DICOM Viewer
iQ-4VIEW
X-Ray Generator
RF Series

Radcal

Channels

Nuclear Medicine

view channel
Image: In vivo imaging of U-87 MG xenograft model with varying mass doses of 89Zr-labeled KLG-3 or isotype control (Photo courtesy of L Gajecki et al.; doi.org/10.2967/jnumed.124.268762)

Novel Radiolabeled Antibody Improves Diagnosis and Treatment of Solid Tumors

Interleukin-13 receptor α-2 (IL13Rα2) is a cell surface receptor commonly found in solid tumors such as glioblastoma, melanoma, and breast cancer. It is minimally expressed in normal tissues, making it... Read more

Imaging IT

view channel
Image: The new Medical Imaging Suite makes healthcare imaging data more accessible, interoperable and useful (Photo courtesy of Google Cloud)

New Google Cloud Medical Imaging Suite Makes Imaging Healthcare Data More Accessible

Medical imaging is a critical tool used to diagnose patients, and there are billions of medical images scanned globally each year. Imaging data accounts for about 90% of all healthcare data1 and, until... Read more
Copyright © 2000-2025 Globetech Media. All rights reserved.

Notice: The user specified as a definer ('admin'@'%') does not exist in /home/www/medsites/shared/includes/database.php on line 307

/home/www/medsites/shared/includes/post_processing.php:42
/home/www/medsites/shared/includes/post_processing.php:5
/home/www/medsites/medicalimaging/index.php:409164 queries executed
1
(65.088272094727): SET sql_mode = 'MYSQL40'
2 (174.99923706055): SELECT folder, element, published, params FROM jos_mambots WHERE published >= 1 AND access <= 0 AND folder = 'system' ORDER BY ordering
3 (272.03559875488): SELECT template FROM jos_templates_menu WHERE client_id = 0 AND ( menuid = 0 OR menuid = 294726218 ) ORDER BY menuid DESC LIMIT 1
4 (550.98533630371): DELETE FROM jos_session WHERE time < 1751162500 AND guest = 1 AND userid = 0
5 (178.09867858887): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1
6 (48.160552978516): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1
7 (344.03800964355): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1
8 (!!!!! 1651.0486602783): SELECT * FROM jos_menu WHERE id = 294726218
9 (758.88633728027): SELECT dp.*, ch.title as channel, ch.name as channel_name, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 #AND dp.cat=10 AND dp.id=294726218 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1
10 (653.02848815918): SELECT dp.*, ch.title as channel, ch.name as channel_name, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 #AND dp.cat=10 AND dp.id=294726218 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1
11 (363.11149597168): SELECT dp.*, ch.title as channel, ch.name as channel_name, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 #AND dp.cat=10 AND dp.id=294726218 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1
12 (!!!!! 4170.8946228027): SELECT * FROM jos_deeppockets WHERE 1=1 AND cat=10 AND type='deeppockets_item' AND published='1' AND (id<>294726218) AND (fid=212) ORDER BY id DESC, `created` DESC LIMIT 0,16
13 (!!!!! 1677.0362854004): SELECT * FROM jos_deeppockets WHERE 1=1 AND cat=10 AND type='deeppockets_item' AND published='1' AND (id<>294726218) AND (fid=212) ORDER BY id DESC, `created` DESC LIMIT 0,16
14 (!!!!! 2731.0848236084): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='P' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_item.fid=212 and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) AND (jos_number.channelID=294726218 OR jos_number.channelID=0) ORDER BY RAND() DESC LIMIT 3
15 (!!!!! 6002.9029846191): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='P' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_item.fid=212 and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) AND (jos_number.channelID=294726218 OR jos_number.channelID=0) ORDER BY RAND() DESC LIMIT 3
16 (!!!!! 2852.201461792): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='P' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) AND (jos_number.channelID=294726218 OR jos_number.channelID=0) ORDER BY RAND() DESC LIMIT 3
17 (!!!!! 1209.020614624): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='P' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) AND (jos_number.channelID=294726218 OR jos_number.channelID=0) ORDER BY RAND() DESC LIMIT 3
18 (!!!!! 3268.0034637451): SELECT name,id,title FROM jos_deeppockets WHERE id=212 LIMIT 1
19 (511.16943359375): SELECT name,id,title FROM jos_deeppockets WHERE id=212 LIMIT 1
20 (!!!!! 1163.9595031738): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294726218 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1
21 (!!!!! 1147.985458374): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294726218 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1
22 (240.08750915527): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294726218 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1
23 (139.95170593262): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294726218 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1
24 (640.869140625): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294726218 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1
25 (483.03604125977): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294726218 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1
26 (273.9429473877): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294726218 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1
27 (60.081481933594): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294726218 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1
28 (155.92575073242): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294726218 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1
29 (332.11708068848): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294726218 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1
30 (360.01205444336): SELECT conference_items.channel_id, conference_items.tracking_code FROM conference_items LEFT JOIN conference_groups ON conference_groups.id = conference_items.group_id LEFT JOIN jos_deeppockets ON jos_deeppockets.id = conference_items.channel_id LEFT JOIN jos_journal ON jos_journal.cat = jos_deeppockets.cat AND jos_journal.real = 1 AND jos_journal.directory IS NOT NULL WHERE 1 = 1 ORDER BY conference_items.id
31 (633.95500183105): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294726218 LIMIT 1
32 (54.121017456055): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294726218 LIMIT 1
33 (355.95893859863): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294726218 LIMIT 1
34 (158.78677368164): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294726218 LIMIT 1
35 (137.0906829834): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294726218 LIMIT 1
36 (32.901763916016): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294726218 LIMIT 1
37 (441.07437133789): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294726218 LIMIT 1
38 (47.922134399414): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294726218 LIMIT 1
39 (777.00614929199): SELECT id, title, module, position, content, showtitle, params FROM jos_modules AS m INNER JOIN jos_modules_menu AS mm ON mm.moduleid = m.id WHERE m.published = 1 AND m.access <= 0 AND m.client_id != 1 AND ( mm.menuid = 0 OR mm.menuid = 294726218 ) ORDER BY ordering
40 (!!!!! 2069.9501037598): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
41 (82.969665527344): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
42 (!!!!! 4389.0476226807): SELECT * FROM jos_bannersmanager_banner WHERE `groupid` = 98 AND `site_id` = 10 AND `published` = 1
43 (!!!!! 7855.8921813965): SELECT * FROM jos_bannersmanager_banner WHERE `groupid` = 99 AND `site_id` = 10 AND `published` = 1
44 (!!!!! 1389.9803161621): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
45 (159.02519226074): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
46 (161.17095947266): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
47 (84.877014160156): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
48 (82.969665527344): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
49 (54.121017456055): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
50 (109.91096496582): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
51 (60.081481933594): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
52 (393.15223693848): SELECT name FROM jos_deeppockets WHERE id=294726218 LIMIT 1
53 (248.19374084473): SELECT name FROM jos_deeppockets_archive WHERE id=294726218 LIMIT 1
54 (48.160552978516): SELECT a.* FROM jos_components AS a WHERE ( a.admin_menu_link = 'option=com_syndicate' OR a.admin_menu_link = 'option=com_syndicate&hidemainmenu=1' ) AND a.option = 'com_syndicate'
55 (57.93571472168): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294726218 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1
56 (496.86431884766): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294726218 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1
57 (!!!!! 1387.1192932129): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
58 (69.141387939453): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
59 (115.87142944336): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
60 (49.829483032227): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
61 (88.930130004883): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1
62 (543.11752319336): SELECT fid FROM jos_deeppockets WHERE id=294726218 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294726218 AND published='1' LIMIT 1
63 (46.014785766602): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`
64 (61.03515625): select jos_twitters.link from jos_twitters where cat=10
65 (30.994415283203): select jos_facebook.link from jos_facebook where cat=10
66 (30.994415283203): select jos_google_plus.link from jos_google_plus where cat=10
67 (29.802322387695): select jos_linkedin.link from jos_linkedin where cat=10
68 (37.908554077148): SELECT fid FROM jos_deeppockets WHERE id=294726218 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294726218 AND published='1' LIMIT 1
69 (32.186508178711): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`
70 (391.96014404297): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294726218 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1
71 (336.88545227051): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294726218 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1
72 (44.107437133789): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`
73 (77.009201049805): SELECT show_live FROM jos_com_show_setting LIMIT 1
74 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1
75 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1
76 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1
77 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1
78 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1
79 (56.028366088867): SELECT show_live FROM jos_com_show_setting LIMIT 1
80 (54.836273193359): SELECT show_live FROM jos_com_show_setting LIMIT 1
81 (40.769577026367): SELECT show_live FROM jos_com_show_setting LIMIT 1
82 (38.14697265625): SELECT show_live FROM jos_com_show_setting LIMIT 1
83 (39.100646972656): SELECT show_live FROM jos_com_show_setting LIMIT 1
84 (37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1
85 (37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1
86 (37.193298339844): SELECT show_live FROM jos_com_show_setting LIMIT 1
87 (54.121017456055): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294726218 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1
88 (30.994415283203): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294726218 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1
89 (35.04753112793): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`
90 (46.968460083008): SELECT show_live FROM jos_com_show_setting LIMIT 1
91 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1
92 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1
93 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1
94 (37.193298339844): SELECT show_live FROM jos_com_show_setting LIMIT 1
95 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1
96 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1
97 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1
98 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1
99 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1
100 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1
101 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1
102 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1
103 (39.815902709961): SELECT show_live FROM jos_com_show_setting LIMIT 1
104 (102.04315185547): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
105 (51.021575927734): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
106 (49.829483032227): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294726218 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1
107 (54.836273193359): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294726218 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1
108 (74.148178100586): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
109 (46.014785766602): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
110 (47.922134399414): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294726218 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1
111 (517.84515380859): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294726218 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1
112 (652.07481384277): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1
113 (354.05158996582): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1
114 (129.93812561035): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
115 (61.988830566406): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
116 (78.916549682617): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
117 (91.075897216797): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
118 (86.069107055664): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
119 (80.82389831543): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
120 (61.988830566406): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
121 (50.067901611328): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
122 (319.9577331543): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`
123 (!!!!! 21399.021148682): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7
124 (550.98533630371): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294726218 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294726218 AND type='deeppockets_item' AND published='1' LIMIT 1
125 (!!!!! 8071.8994140625): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3
126 (87.976455688477): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3
127 (38.862228393555): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1
128 (34.093856811523): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1
129 (!!!!! 1094.1028594971): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1
130 (85.115432739258): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1
131 (321.1498260498): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1
132 (39.100646972656): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1
133 (40.054321289062): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1
134 (28.848648071289): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1
135 (524.99771118164): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1
136 (374.79400634766): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1
137 (39.100646972656): SELECT name FROM jos_deeppockets WHERE id=212
138 (33.855438232422): SELECT name FROM jos_deeppockets WHERE id=212
139 (571.01249694824): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3
140 (485.89706420898): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3
141 (92.029571533203): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
142 (54.121017456055): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
143 (!!!!! 9422.779083252): TRUNCATE TABLE jos_trademed_module
144 (98.943710327148): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294726218 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1
145 (72.956085205078): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294726218 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1
146 (445.12748718262): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1
147 (52.928924560547): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1
148 (61.988830566406): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
149 (83.92333984375): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
150 (!!!!! 1753.0918121338): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6
151 (118.97087097168): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
152 (77.009201049805): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
153 (71.048736572266): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294726218 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294726218 AND type='deeppockets_item' AND published='1' LIMIT 1
154 (54.121017456055): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)
155 (50.067901611328): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)
156 (64.849853515625): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1
157 (147.10426330566): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
158 (75.101852416992): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294726218 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294726218 AND published='1' LIMIT 1
159 (37.908554077148): select jos_twitters.link from jos_twitters where cat=10
160 (28.133392333984): select jos_facebook.link from jos_facebook where cat=10
161 (29.802322387695): select jos_google_plus.link from jos_google_plus where cat=10
162 (29.087066650391): select jos_linkedin.link from jos_linkedin where cat=10
163 (312.80517578125): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)
164 (!!!!! 1171.1120605469): insert into jos_banners_delta values (14615,'2025-06-29 02:16:40','216.73.216.249','view'),(14202,'2025-06-29 02:16:40','216.73.216.249','view'),(14203,'2025-06-29 02:16:40','216.73.216.249','view')