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Multi-Beam OCT Scanner Provides Detailed Images of Subsurface Skin Microstructure at Resolutions Better than Ultrasound and MRI

By MedImaging International staff writers
Posted on 05 Oct 2009

A new optical coherence tomography (OCT) scanner with hand-held probe uses multi-beam OCT to provide images of surface tissue at extraordinarily high resolution--better than 7.5 microns lateral and 10 microns axial resolution--far higher than is possible with other modalities, such as magnetic resonance imaging (MRI) and ultrasound, revealing previously hidden details of tissue microstructure.

Multi-beam OCT uses four laser beams to achieve twice the lateral image resolution of traditional single-beam OCT, which is crucial to providing precise, clear images of the subject matter's microstructure. Michelson Diagnostics, Ltd. (Orpington, UK) has announced the award of a CE-marking for its new VivoSight OCT scanner, confirming its compliance with the European Medical Device Directive. The CE-Marking approval enables clinical use of the product in Europe and nonclinical use of the product worldwide. Moreover, the company has been awarded IS0-13485 status, which enables Michelson to manufacture and sell medical products in Europe.

Martin Johns, operations director and quality representative for Michelson Diagnostics said, "These certifications mark an important milestone in the progress of the company. They confirm that our products have met rigorous quality and safety standards required by European regulatory authorities. We are currently preparing our FDA [U.S. Food and Drug Administration] 510(k) submission, which, if successful, will enable clinical sales in the US to commence in the first half of 2010."

When the scanner's hand-held probe is positioned over the tissue, it can capture either two-dimensional (2D) or 3D images of a 5-mm square region. Tissue microstructure features such as epidermis, dermis, and sublayers can be imaged, in addition to subsurface blood vessels. VivoSight captures and displays images in real time, for instant visual feedback. The captured video data can be instantly replayed for review, or stored for later analysis.

Michelson is applying multi-beam OCT to the diagnosis, monitoring, and treatment of cancer, particularly dermal and oral cancer. MDL is working closely with leading clinicians, who believe that multi-beam OCT, by providing a new, detailed window into the body, will accelerate the care of cancer, enabling faster, more accurate treatment that will save lives and produce substantial cost savings to the medical services.

Michelson Diagnostics' medical applications director, Dr. Gordon McKenzie, explained, "Since the VivoSight scanner provides great imaging depth at very good resolution, it could play an important role in the preoperative diagnostics of early carcinomas in the skin. In addition, it can help eliminate the need for multiple biopsies since the technology can provide a view of subsurface tissue that would previously have required extraction."

In vivo trials of the VivoSight scanner have recently begun. The first trial, which is a collaboration between Michelson Diagnostics, Ludwig Maximilians University of Munich (Germany), and University College Hospital (London, UK), will evaluate the capability of the probe to be used to differentiate premalignant and early malignant lesions, and also to demarcate nonmelanoma skin cancers before planned surgical excision. At least 100 patients will be scanned.

Nonclinical applications of the technology will help pharmaceutical cosmetic companies and developers of cosmetic aesthetic equipment to assess the effectiveness of their cosmetic products and aesthetic procedures. Anticipated applications include observing before and after subdermal images of the skin in response to treatments for wrinkles, skin-texture, discoloration, pigmentation, and hair removal.

Michelson Diagnostics is focused in the design and delivery of multi-beam OCT products for scientific research and healthcare imaging.

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55 (119.92454528809): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725737 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725737 AND published='1' LIMIT 1

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57 (458.0020904541): SELECT name FROM jos_deeppockets WHERE id=294725737 LIMIT 1

58 (335.9317779541): SELECT name FROM jos_deeppockets_archive WHERE id=294725737 LIMIT 1

59 (72.956085205078): SELECT a.* FROM jos_components AS a WHERE ( a.admin_menu_link = 'option=com_syndicate' OR a.admin_menu_link = 'option=com_syndicate&hidemainmenu=1' ) AND a.option = 'com_syndicate'

60 (91.075897216797): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294725737 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

61 (593.90068054199): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294725737 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

62 (!!!!! 1914.0243530273): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725737 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725737 AND published='1' LIMIT 1

63 (61.988830566406): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725737 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725737 AND published='1' LIMIT 1

64 (468.96934509277): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725737 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725737 AND published='1' LIMIT 1

65 (80.108642578125): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725737 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725737 AND published='1' LIMIT 1

66 (297.06954956055): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

67 (718.11676025391): SELECT fid FROM jos_deeppockets WHERE id=294725737 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294725737 AND published='1' LIMIT 1

68 (46.968460083008): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

69 (463.00888061523): select jos_twitters.link from jos_twitters where cat=10

70 (118.97087097168): select jos_facebook.link from jos_facebook where cat=10

71 (99.897384643555): select jos_google_plus.link from jos_google_plus where cat=10

72 (467.06199645996): select jos_linkedin.link from jos_linkedin where cat=10

73 (395.05958557129): SELECT fid FROM jos_deeppockets WHERE id=294725737 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294725737 AND published='1' LIMIT 1

74 (410.79521179199): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

75 (436.06758117676): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294725737 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

76 (699.04327392578): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294725737 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

77 (52.928924560547): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

78 (83.92333984375): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (46.014785766602): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (67.949295043945): SELECT show_live FROM jos_com_show_setting LIMIT 1

89 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

90 (29.802322387695): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (59.843063354492): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294725737 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

93 (43.153762817383): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294725737 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

94 (50.067901611328): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

95 (54.836273193359): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

105 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

106 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

107 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

108 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

109 (!!!!! 1194.0002441406): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725737 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725737 AND published='1' LIMIT 1

110 (54.836273193359): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725737 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725737 AND published='1' LIMIT 1

111 (74.863433837891): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294725737 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (497.10273742676): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294725737 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

113 (78.916549682617): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725737 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725737 AND published='1' LIMIT 1

114 (46.968460083008): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725737 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725737 AND published='1' LIMIT 1

115 (!!!!! 1652.9560089111): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294725737 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

116 (427.9613494873): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294725737 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

117 (55.074691772461): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294725735 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

118 (349.99847412109): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294725735 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

119 (778.9134979248): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

120 (594.8543548584): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

121 (96.08268737793): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725737 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725737 AND published='1' LIMIT 1

122 (66.995620727539): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725737 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725737 AND published='1' LIMIT 1

123 (74.148178100586): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725737 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725737 AND published='1' LIMIT 1

124 (55.074691772461): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725737 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725737 AND published='1' LIMIT 1

125 (64.13459777832): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725737 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725737 AND published='1' LIMIT 1

126 (55.074691772461): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725737 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725737 AND published='1' LIMIT 1

127 (75.101852416992): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725737 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725737 AND published='1' LIMIT 1

128 (53.882598876953): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725737 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725737 AND published='1' LIMIT 1

129 (499.96376037598): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

130 (!!!!! 47831.058502197): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

131 (549.0779876709): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294725737 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294725737 AND type='deeppockets_item' AND published='1' LIMIT 1

132 (!!!!! 18798.112869263): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

133 (98.943710327148): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

134 (72.956085205078): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

135 (41.007995605469): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

136 (75.817108154297): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

137 (34.093856811523): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

138 (368.11828613281): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

139 (41.007995605469): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

140 (35.04753112793): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

141 (30.994415283203): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

142 (530.00450134277): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725737 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

143 (385.04600524902): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725737 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

144 (46.014785766602): SELECT name FROM jos_deeppockets WHERE id=212

145 (30.994415283203): SELECT name FROM jos_deeppockets WHERE id=212

146 (630.14030456543): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

147 (622.03407287598): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

148 (77.962875366211): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725737 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725737 AND published='1' LIMIT 1

149 (56.982040405273): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725737 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725737 AND published='1' LIMIT 1

150 (!!!!! 14307.022094727): TRUNCATE TABLE jos_trademed_module

151 (113.01040649414): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294725737 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

152 (50.783157348633): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294725737 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

153 (!!!!! 3787.9943847656): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725737 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

154 (108.95729064941): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725737 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

155 (61.03515625): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725737 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725737 AND published='1' LIMIT 1

156 (41.961669921875): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725737 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725737 AND published='1' LIMIT 1

157 (!!!!! 1327.0378112793): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

158 (77.009201049805): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725737 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725737 AND published='1' LIMIT 1

159 (61.988830566406): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725737 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725737 AND published='1' LIMIT 1

160 (39.100646972656): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294725737 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294725737 AND type='deeppockets_item' AND published='1' LIMIT 1

161 (33.140182495117): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=0 or channel_id is null)

162 (46.014785766602): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=0 or channel_id is null)

163 (66.041946411133): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

164 (452.04162597656): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725737 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725737 AND published='1' LIMIT 1

165 (71.048736572266): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294725737 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294725737 AND published='1' LIMIT 1

166 (40.054321289062): select jos_twitters.link from jos_twitters where cat=10

167 (37.193298339844): select jos_facebook.link from jos_facebook where cat=10

168 (42.915344238281): select jos_google_plus.link from jos_google_plus where cat=10

169 (31.948089599609): select jos_linkedin.link from jos_linkedin where cat=10

170 (319.00405883789): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

171 (!!!!! 1183.9866638184): insert into jos_banners_delta values (14615,'2025-08-24 07:49:11','216.73.216.171','view'),(14202,'2025-08-24 07:49:11','216.73.216.171','view'),(14203,'2025-08-24 07:49:11','216.73.216.171','view')

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