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AAPM 2025 - 67th Annual Meeting & Exhibition of the American Association of Physicists in Medicine

MRI Technique Estimates Brain Tissue at Risk of Infarct from Stroke

By MedImaging International staff writers
Posted on 26 Jan 2009

Image: On left (A) An infarct already formed is identified by a sequence of classic diffusion MRI. On right (B) Derived from the original diffusion MRI, the Infarct is plotted on the apparent diffusion chart. The NEURiNFARCT technique predicts the future of the infarct and its growth potential in the brain of the patient, allowing the neurologist to estimate the risk / benefit ratio of aggressive treatments (Photo courtesy of the Cognitive Neuroscience and Brain Imaging Laboratory of the French National Center for Scientific Research and the Acute Stroke Center of the Pitié-Salpêtrière General Hospital).

A new approach to the early prediction of the evolution of cerebral infarcts caused by stroke has just been evaluated on nearly 100 patients. The new imaging technique yields an estimate of the final level of brain tissues at risk of infarction for acute stroke patients. This new technique is derived from an unprecedented analysis of magnetic resonance imaging (MRI) data.

The application, called the NEURiNFARCT technique, results from the collaboration of the Cognitive Neuroscience and Brain Imaging Laboratory of the French National Center for Scientific Research (CNRS; Paris), and the Acute Stroke Center of the Pitié-Salpêtrière General Hospital (Paris France). The results of Dr. Charlotte Rosso and her coauthors study, which were published online in November 18, 2008, on the Radiology journal web site, demonstrate how this new technique may help predict within minutes the severity of stroke infarcts using a conventional clinical MR scanner.

Ischemic stroke is caused by clogged blood vessels, thereby putting target organs at risk of cellular death. NEURiNFARCT identifies the ischemic penumbra, a region subject to rapid developments within a few hours after the onset of a stroke, and conducive to severe irreversible brain lesions. Contrary to the zone of initial infarct, the penumbra region may be saved during the early acute phase of stroke, and therefore, the risk of subsequent deficits for the patients may be reduced--using thrombolytic medication, although this treatment has its share of possible secondary hemorrhagic complications. Early evaluation of the severity of stroke could therefore help assist the critical fast therapeutic decision-making process.

This challenge has fostered the research project from which NEURiNFARCT has originated. Existing MRI-based approaches necessitated the injection of a contrast agent; something NEURiNFARCT could make obsolete as the new technique only necessitates basic routine diffusion MR image sequences. The diffusion data measure the mobility of water molecules in tissues, which is considerably reduced in the core of the infarct lesion and to a much lesser extent, in the ischemic penumbra region. Sight identification of these alterations of the MRI data in the region at risk of infarction is impossible. The new approach, therefore, proposes an image analysis approach based on a model of the ongoing infarct growth in brain tissues.

The results from the study demonstrated that NEURiNFARCT performs at least as well as alternative approaches using perfusion techniques in MRI or computed tomography (CT) scanners, though these latter are conditioned to the delicate intravenous injection of a contrast agent. NEURiNFARCT has the secondary advantages in the context of acute emergency care that it is an automatic and standard procedure.

This new approach, according to the investigators, is likely to significantly contribute to rapid therapeutic decision-making and to faster throughput in the assessment of new drug molecules by the pharmaceutical industry. A NEURiNFARCT software prototype is currently contributing to ongoing research studies on treatments against evolving brain infarcts. This is of critical importance in the context of stroke, which concerns as many patients as Alzheimer and Parkinson's diseases. The NEURiNFARCT technique has been internationally patented.

Related Links:
French National Center for Scientific Research

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59 (104.18891906738): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294721818 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294721818 AND published='1' LIMIT 1

60 (81.062316894531): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294721818 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294721818 AND published='1' LIMIT 1

61 (114.91775512695): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

62 (682.83081054688): SELECT fid FROM jos_deeppockets WHERE id=294721818 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294721818 AND published='1' LIMIT 1

63 (463.96255493164): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

64 (76.055526733398): select jos_twitters.link from jos_twitters where cat=10

65 (40.769577026367): select jos_facebook.link from jos_facebook where cat=10

66 (53.167343139648): select jos_google_plus.link from jos_google_plus where cat=10

67 (42.915344238281): select jos_linkedin.link from jos_linkedin where cat=10

68 (58.889389038086): SELECT fid FROM jos_deeppockets WHERE id=294721818 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294721818 AND published='1' LIMIT 1

69 (45.7763671875): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

70 (406.02684020996): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294721818 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (349.04479980469): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294721818 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (56.982040405273): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (63.896179199219): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (65.088272094727): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (57.93571472168): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (39.100646972656): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (33.855438232422): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (33.140182495117): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (33.855438232422): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (77.962875366211): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294721818 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (38.862228393555): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294721818 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (42.915344238281): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (49.114227294922): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (55.789947509766): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (51.021575927734): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (51.021575927734): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (37.908554077148): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (85.830688476562): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294721818 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294721818 AND published='1' LIMIT 1

105 (56.028366088867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294721818 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294721818 AND published='1' LIMIT 1

106 (56.028366088867): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294721818 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (48.87580871582): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294721818 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (128.98445129395): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294721818 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294721818 AND published='1' LIMIT 1

109 (55.074691772461): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294721818 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294721818 AND published='1' LIMIT 1

110 (54.121017456055): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294721818 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (591.03965759277): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294721818 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (632.04765319824): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (402.92739868164): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (84.877014160156): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294721818 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294721818 AND published='1' LIMIT 1

115 (49.114227294922): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294721818 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294721818 AND published='1' LIMIT 1

116 (117.06352233887): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294721818 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294721818 AND published='1' LIMIT 1

117 (40.054321289062): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294721818 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294721818 AND published='1' LIMIT 1

118 (51.975250244141): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294721818 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294721818 AND published='1' LIMIT 1

119 (38.862228393555): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294721818 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294721818 AND published='1' LIMIT 1

120 (49.114227294922): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294721818 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294721818 AND published='1' LIMIT 1

121 (38.14697265625): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294721818 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294721818 AND published='1' LIMIT 1

122 (266.07513427734): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 20604.848861694): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (607.01370239258): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294721818 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294721818 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 7786.9892120361): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (131.84547424316): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (495.91064453125): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (106.8115234375): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (312.08992004395): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (94.890594482422): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (236.98806762695): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (64.13459777832): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (280.85708618164): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (69.856643676758): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (491.14227294922): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294721818 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (469.20776367188): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294721818 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (282.04917907715): SELECT name FROM jos_deeppockets WHERE id=212

138 (36.001205444336): SELECT name FROM jos_deeppockets WHERE id=212

139 (667.09518432617): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (524.99771118164): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (85.115432739258): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294721818 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294721818 AND published='1' LIMIT 1

142 (62.942504882812): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294721818 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294721818 AND published='1' LIMIT 1

143 (!!!!! 15959.978103638): TRUNCATE TABLE jos_trademed_module

144 (646.11434936523): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294721818 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (143.05114746094): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294721818 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (!!!!! 1403.0933380127): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294721818 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (231.02760314941): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294721818 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (!!!!! 4286.0507965088): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294721818 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294721818 AND published='1' LIMIT 1

149 (!!!!! 3250.1220703125): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294721818 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294721818 AND published='1' LIMIT 1

150 (!!!!! 1361.1316680908): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (66.041946411133): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294721818 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294721818 AND published='1' LIMIT 1

152 (55.074691772461): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294721818 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294721818 AND published='1' LIMIT 1

153 (116.10984802246): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294721818 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294721818 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (32.901763916016): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

155 (28.133392333984): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

156 (27.894973754883): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (!!!!! 3585.1001739502): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294721818 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294721818 AND published='1' LIMIT 1

158 (73.909759521484): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294721818 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294721818 AND published='1' LIMIT 1

159 (344.99168395996): select jos_twitters.link from jos_twitters where cat=10

160 (537.87231445312): select jos_facebook.link from jos_facebook where cat=10

161 (!!!!! 1384.973526001): select jos_google_plus.link from jos_google_plus where cat=10

162 (40.054321289062): select jos_linkedin.link from jos_linkedin where cat=10

163 (385.04600524902): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

164 (995.87440490723): insert into jos_banners_delta values (14615,'2025-06-29 21:25:05','216.73.216.249','view'),(14202,'2025-06-29 21:25:05','216.73.216.249','view'),(14203,'2025-06-29 21:25:05','216.73.216.249','view')

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