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AAPM 2025 - 67th Annual Meeting & Exhibition of the American Association of Physicists in Medicine

Human Brain Relies on Old and New Mechanisms for Diminishing Fear

By MedImaging International staff writers
Posted on 06 Oct 2008

A new study suggests that although humans may have developed complex thought processes that can help to regulate their emotions, these processes are linked with evolutionarily older mechanisms that are common across species. The new research provides new insights into the way the brain manages fear, and may help in the search for novel pharmacologic and therapeutic treatments for anxiety disorders.

"The ability to eliminate, control, or diminish negative emotional responses is important for adaptive function and critical in the treatment of psychopathology,” said study author, Dr. Mauricio Delgado, from Rutgers University (New Brunswick, NJ, USA). "Recent research examining the neural mechanisms for diminishing fears has focused on two techniques: [fear] extinction, which has been explored across species, and cognitive emotion regulation strategies, which are unique to humans.” Earlier research in rodents and humans has implicated activity in the amygdala and ventral medial prefrontal cortex (vmPFC) in extinction. In contrast, neural circuits underlying cognitive strategies to regulate emotions are not as well understood.

Dr. Delgado, Dr. Elizabeth A. Phelps, from New York University (NYU; New York, NY, USA), and their colleagues were interested in examining the similarities and differences of diminishing fear through both techniques. They used similar experimental paradigms with different means of controlling fear to directly compare the neural mechanisms that mediate extinction and emotional regulation. A typical fear conditioning method was combined with a measurement of physiologic arousal to examine extinction, while a cognitive emotion regulation strategy was also implemented. Functional magnetic resonance imaging (fMRI) scanning was utilized to compare the neural activation patterns of extinction and emotional regulation.

The researchers noted that the lateral prefrontal cortex regions engaged by cognitive emotion regulation strategies influenced the amygdala and diminished fear through similar vmPFC connections that are thought to suppress the amygdala during extinction. Taken together, the findings indicate that there is overlap in the neural circuitry of diminishing learned fears through emotion regulation and extinction and that vmPFC may play a general regulatory role in diminishing fear across a range of paradigms.

"Our results suggest that even though humans may have developed unique capabilities for using complex cognitive strategies to control emotion, these strategies may influence the amygdala through phylogenetically shared mechanisms of extinction," explained Dr. Phelps. "Extinction and cognitive emotion regulation may be, in part, complementary in that they rely on a common neural circuitry and, perhaps, similar neurophysiological and neurochemical mechanisms.”

The study was published in the September 11, 2008, issue of the journal Neuron.

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New York University

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63 (530.95817565918): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

64 (64.849853515625): select jos_twitters.link from jos_twitters where cat=10

65 (32.901763916016): select jos_facebook.link from jos_facebook where cat=10

66 (38.14697265625): select jos_google_plus.link from jos_google_plus where cat=10

67 (38.862228393555): select jos_linkedin.link from jos_linkedin where cat=10

68 (46.014785766602): SELECT fid FROM jos_deeppockets WHERE id=294720569 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294720569 AND published='1' LIMIT 1

69 (41.007995605469): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

70 (718.11676025391): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294720569 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (425.10032653809): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294720569 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (65.088272094727): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (50.067901611328): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (77.009201049805): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (970.84045410156): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294720569 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (60.796737670898): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294720569 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (37.908554077148): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (471.11511230469): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (231.98127746582): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (52.928924560547): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (154.01840209961): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (442.9817199707): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (62.942504882812): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (199.0795135498): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (193.11904907227): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (132.08389282227): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (630.14030456543): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720569 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720569 AND published='1' LIMIT 1

105 (79.870223999023): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720569 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720569 AND published='1' LIMIT 1

106 (212.19253540039): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294720569 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (51.975250244141): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294720569 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (828.98139953613): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720569 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720569 AND published='1' LIMIT 1

109 (51.975250244141): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720569 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720569 AND published='1' LIMIT 1

110 (81.062316894531): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294720569 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (698.08959960938): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294720569 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (722.16987609863): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (473.97613525391): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (144.95849609375): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720569 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720569 AND published='1' LIMIT 1

115 (77.962875366211): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720569 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720569 AND published='1' LIMIT 1

116 (68.187713623047): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720569 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720569 AND published='1' LIMIT 1

117 (39.815902709961): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720569 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720569 AND published='1' LIMIT 1

118 (86.069107055664): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720569 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720569 AND published='1' LIMIT 1

119 (72.002410888672): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720569 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720569 AND published='1' LIMIT 1

120 (76.055526733398): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720569 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720569 AND published='1' LIMIT 1

121 (61.988830566406): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720569 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720569 AND published='1' LIMIT 1

122 (403.88107299805): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 23489.952087402): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (653.98216247559): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294720569 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294720569 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 8014.9173736572): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (204.08630371094): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (58.889389038086): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (40.054321289062): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (74.148178100586): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (38.14697265625): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (467.06199645996): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (43.869018554688): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (40.054321289062): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (38.14697265625): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (497.10273742676): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720569 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (370.97930908203): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720569 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (229.1202545166): SELECT name FROM jos_deeppockets WHERE id=212

138 (44.107437133789): SELECT name FROM jos_deeppockets WHERE id=212

139 (560.04524230957): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (695.94383239746): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (88.930130004883): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720569 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720569 AND published='1' LIMIT 1

142 (49.114227294922): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720569 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720569 AND published='1' LIMIT 1

143 (!!!!! 8993.8640594482): TRUNCATE TABLE jos_trademed_module

144 (201.94053649902): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294720569 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (81.062316894531): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294720569 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (951.05171203613): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720569 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (85.830688476562): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720569 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (109.91096496582): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720569 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720569 AND published='1' LIMIT 1

149 (53.882598876953): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720569 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720569 AND published='1' LIMIT 1

150 (!!!!! 1600.0270843506): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (94.890594482422): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720569 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720569 AND published='1' LIMIT 1

152 (60.081481933594): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720569 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720569 AND published='1' LIMIT 1

153 (85.115432739258): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294720569 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294720569 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (41.961669921875): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

155 (34.093856811523): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

156 (45.061111450195): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (64.849853515625): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720569 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720569 AND published='1' LIMIT 1

158 (108.00361633301): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720569 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720569 AND published='1' LIMIT 1

159 (52.928924560547): select jos_twitters.link from jos_twitters where cat=10

160 (34.093856811523): select jos_facebook.link from jos_facebook where cat=10

161 (32.186508178711): select jos_google_plus.link from jos_google_plus where cat=10

162 (40.054321289062): select jos_linkedin.link from jos_linkedin where cat=10

163 (406.98051452637): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

164 (!!!!! 1250.9822845459): insert into jos_banners_delta values (14615,'2025-06-30 02:53:37','216.73.216.249','view'),(14202,'2025-06-30 02:53:37','216.73.216.249','view'),(14203,'2025-06-30 02:53:37','216.73.216.249','view')

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