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AAPM 2025 - 67th Annual Meeting & Exhibition of the American Association of Physicists in Medicine

First U.S. Patient Undergoes MR-Guided Focused Ultrasound Procedure

By MedImaging International staff writers
Posted on 28 Aug 2008

A company that developed a non-invasive, radiation-free magnetic resonance-guided focused ultrasound (MRgFUS) system has been given the first U.S. patient to treat in the company's pivotal trial to evaluate the safety and effectiveness of the system as a pain-relieving treatment for patients with bone metastases who have failed an initial round of palliative radiation.

The ExAblate system, developed by InSightec, Ltd. (Tirat Carmel, Israel), was approved to treat women suffering from symptomatic uterine fibroids in 2004. Over 4,000 women have already undergone treatment with ExAblate worldwide. "Pain from tumors that have spread to the bone is the most common kind of pain for cancer patients,” said Dr. Kobi Vortman, InSightec's president and CEO. "Many patients are too weak to withstand invasive procedures to quell their pain if it persists or recurs after palliative radiation. We look forward to advancing the trial in hopes that ExAblate may provide a noninvasive, ionized radiation-free means to improve the quality of life of late-stage cancer patients.”

Bone is the third most common tissue to which cancer spreads, after the lungs and liver. Nearly all patients with metastatic prostate cancer have skeletal metastases and in breast cancer, bone is the second most common site of metastatic spread, affecting 90% of patients with progressive breast cancer. Most cancer patients suffer from pain; controlling it and managing its symptoms are important treatment goals.

Using the ExAblate system, the physician uses the magnetic resonance imaging (MRI) to visualize the patient's anatomy and then aims focused ultrasound waves at the targeted tissue to thermally ablate, or destroy it. The MRI allows the clincian to track and continuously adjust the treatment in real time. The patient is consciously sedated to alleviate pain and minimize motion. Due to the high acoustic absorption and low thermal conductivity of the bone cortex, it is possible to use a low level of energy and still achieve a localized heating effect while minimizing damage to adjacent tissue.

InSightec hopes to enroll patients with bone metastases who have failed palliative radiation therapy into the study, which is being conducted at 15 sites across the United States. The company is in the process of obtaining Institutional Review Board (IRB) approval from the remaining sites.

The ExAblate 2000 system received the European CE Mark certification for pain palliation of bone metastases in June. In clinical studies, which supported the CE mark, the majority of patients reported pain relief within days of treatment.

ExAblate is the first system to use the breakthrough MRgFUS technology that combines MRI to visualize the body anatomy, plan and monitor treatment outcome in real time, and high intensity focused ultrasound to thermally ablate tumors inside the body non-invasively. MR thermometry, provided uniquely by the system, allows the physician to control and adjust the treatment in real time to ensure that the targeted tumor is fully treated and surrounding tissue is spared.

Approved by the U.S. Food and Drug Administration in 2004 as a treatment for symptomatic uterine fibroids, ExAblate has been recognized for its innovation and potential to serve mankind and has been awarded the 2004 European Union's Information Society Technologies grand prize, The Wall Street Journal's 2004 Technology Innovation Awards, Advanced Imaging's 2005 Solutions of the Year, the Red Herring 100 Europe 2007 Award, and currently one of the World Economic Forum Technology Pioneer 2008.

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60 (82.969665527344): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720122 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720122 AND published='1' LIMIT 1

61 (94.890594482422): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

62 (550.98533630371): SELECT fid FROM jos_deeppockets WHERE id=294720122 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294720122 AND published='1' LIMIT 1

63 (45.061111450195): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

64 (102.04315185547): select jos_twitters.link from jos_twitters where cat=10

65 (44.107437133789): select jos_facebook.link from jos_facebook where cat=10

66 (74.863433837891): select jos_google_plus.link from jos_google_plus where cat=10

67 (42.915344238281): select jos_linkedin.link from jos_linkedin where cat=10

68 (34.093856811523): SELECT fid FROM jos_deeppockets WHERE id=294720122 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294720122 AND published='1' LIMIT 1

69 (54.121017456055): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=212 ORDER BY `ordering`

70 (519.0372467041): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294720122 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (167.1314239502): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294720122 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (46.014785766602): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (49.829483032227): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (42.915344238281): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294720122 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (30.994415283203): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294720122 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (35.04753112793): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (59.127807617188): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (33.140182495117): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (33.140182495117): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (73.909759521484): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720122 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720122 AND published='1' LIMIT 1

105 (55.789947509766): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720122 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720122 AND published='1' LIMIT 1

106 (51.975250244141): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294720122 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (45.061111450195): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294720122 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (69.141387939453): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720122 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720122 AND published='1' LIMIT 1

109 (46.968460083008): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720122 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720122 AND published='1' LIMIT 1

110 (44.107437133789): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294720122 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (434.87548828125): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294720122 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (580.78765869141): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (381.9465637207): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (77.009201049805): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720122 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720122 AND published='1' LIMIT 1

115 (56.982040405273): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720122 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720122 AND published='1' LIMIT 1

116 (46.968460083008): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720122 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720122 AND published='1' LIMIT 1

117 (36.001205444336): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720122 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720122 AND published='1' LIMIT 1

118 (42.915344238281): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720122 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720122 AND published='1' LIMIT 1

119 (38.14697265625): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720122 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720122 AND published='1' LIMIT 1

120 (51.975250244141): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720122 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720122 AND published='1' LIMIT 1

121 (37.908554077148): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720122 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720122 AND published='1' LIMIT 1

122 (169.99244689941): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 19223.928451538): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (481.84394836426): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294720122 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294720122 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (92.983245849609): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (45.061111450195): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (60.081481933594): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (30.040740966797): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (38.14697265625): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (37.193298339844): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (40.054321289062): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (36.954879760742): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (44.107437133789): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (36.954879760742): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (491.14227294922): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720122 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (339.03121948242): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720122 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (56.028366088867): SELECT name FROM jos_deeppockets WHERE id=212

138 (41.007995605469): SELECT name FROM jos_deeppockets WHERE id=212

139 (611.0668182373): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (591.03965759277): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))212((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (97.036361694336): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720122 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720122 AND published='1' LIMIT 1

142 (72.956085205078): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720122 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720122 AND published='1' LIMIT 1

143 (!!!!! 10628.938674927): TRUNCATE TABLE jos_trademed_module

144 (82.969665527344): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294720122 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (118.01719665527): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294720122 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (830.88874816895): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720122 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (47.922134399414): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720122 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (51.975250244141): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720122 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720122 AND published='1' LIMIT 1

149 (40.054321289062): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720122 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720122 AND published='1' LIMIT 1

150 (!!!!! 1050.9490966797): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (53.882598876953): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720122 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720122 AND published='1' LIMIT 1

152 (40.054321289062): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720122 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720122 AND published='1' LIMIT 1

153 (36.001205444336): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294720122 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294720122 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (29.087066650391): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

155 (26.941299438477): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=212 or channel_id is null)

156 (29.087066650391): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (172.85346984863): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720122 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720122 AND published='1' LIMIT 1

158 (77.962875366211): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294720122 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294720122 AND published='1' LIMIT 1

159 (43.153762817383): select jos_twitters.link from jos_twitters where cat=10

160 (30.994415283203): select jos_facebook.link from jos_facebook where cat=10

161 (31.948089599609): select jos_google_plus.link from jos_google_plus where cat=10

162 (30.994415283203): select jos_linkedin.link from jos_linkedin where cat=10

163 (253.91578674316): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

164 (!!!!! 1054.048538208): insert into jos_banners_delta values (14615,'2025-06-30 07:50:54','216.73.216.249','view'),(14202,'2025-06-30 07:50:54','216.73.216.249','view'),(14203,'2025-06-30 07:50:54','216.73.216.249','view')

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