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Ultrasound Device Non-Invasively Improves Blood Circulation in Lower Limbs

By MedImaging International staff writers
Posted on 09 Nov 2024

Impaired blood circulation in the lower limbs is a common health issue among the elderly and is a significant complication of diabetes, often referred to as diabetic foot. More...

This condition arises due to impaired tissue circulation and progressive neuropathy, causing foot tissues to become insensitive and unable to respond appropriately to trauma. As a result, patients may experience progressive ulceration, wound infection, tissue necrosis, and ultimately, amputation. With limited options for pharmacological treatment, alternative and particularly non-invasive therapies, such as ultrasound energy, are gaining importance. Researchers have now created an ultrasonic foot stimulation device that can non-invasively enhance blood circulation in the lower limbs.

This innovative device was developed through collaboration between scientists from the Kaunas University of Technology (KTU, Kaunas, Lithuania) and the Lithuanian University of Health Sciences (LSMU, Kaunas, Lithuania). Ultrasound has recently found widespread application across various medical fields as a therapeutic method. It can affect diverse body tissues and structures, including bones, skin, muscles, and biological fluids like blood. The application of ultrasound can alleviate pain, reduce spasms and inflammation, and stimulate blood flow. Additionally, it can activate central blood flow in the body's main blood vessels, closer to the heart and lungs, through the retrograde neurogenic pathway, broadening its therapeutic potential.

The developed device employs specific piezoelectric elements to produce a broad spectrum of acoustic ultrasound waves in response to an electrical signal. By selecting the appropriate parameters, the ultrasound is transmitted to the foot tissues, stimulating blood flow throughout the leg. The vibrations caused by electric current passing through the elements generate acoustic waves that penetrate the skin and reach deeper tissues, creating vibrations that enhance the tone of blood vessel walls. This process improves blood flow in superficial tissues and modulates the activity of blood-forming components, including erythrocytes, leukocytes, and thrombocytes. Consequently, it regulates thrombogenesis, immune response, and inflammatory processes, all vital for maintaining normal vascular and tissue function. Furthermore, ultrasound waves can influence nerve structures since all blood vessels are innervated, thus activating vascular tone across a broad tissue area.

It is important to note that the therapeutic effects of ultrasound depend on physical parameters such as wave frequency, power, and intensity. The newly developed device utilizes low-frequency ultrasound, operating in a non-contact and non-thermal manner to minimize potential adverse effects. The researchers believe that, upon creating a commercial prototype, this device could significantly transform medical practice in rehabilitation hospitals, preventive medicine clinics, and nursing facilities. Its portability, safety, and capability to address a wide range of lower extremity circulatory disorders position it as a promising tool for the future. The device can also be customized for individual use through appropriate software modifications, making it beneficial for patients with diabetes and other peripheral circulatory disorders, as well as for older adults experiencing chronic vascular dysfunction. Additionally, with the right parameters, ultrasound may facilitate the targeted delivery of chemotherapeutic drugs, reducing overall toxic effects on the body.

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76 (51.021575927734): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

77 (72.956085205078): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (29.802322387695): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

89 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

90 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (133.99124145508): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803027 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803027 AND published='1' LIMIT 1

92 (339.03121948242): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803027 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803027 AND published='1' LIMIT 1

93 (102.04315185547): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294803027 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

94 (143.05114746094): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803027 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803027 AND published='1' LIMIT 1

95 (80.108642578125): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803027 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803027 AND published='1' LIMIT 1

96 (636.10076904297): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294803027 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

97 (888.82446289062): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

98 (891.92390441895): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

99 (221.01402282715): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803027 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803027 AND published='1' LIMIT 1

100 (82.015991210938): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803027 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803027 AND published='1' LIMIT 1

101 (100.85105895996): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803027 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803027 AND published='1' LIMIT 1

102 (71.048736572266): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803027 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803027 AND published='1' LIMIT 1

103 (73.909759521484): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803027 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803027 AND published='1' LIMIT 1

104 (55.074691772461): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803027 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803027 AND published='1' LIMIT 1

105 (66.041946411133): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803027 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803027 AND published='1' LIMIT 1

106 (56.028366088867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803027 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803027 AND published='1' LIMIT 1

107 (710.01052856445): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

108 (!!!!! 29724.836349487): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

109 (!!!!! 1205.9211730957): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294803027 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294803027 AND type='deeppockets_item' AND published='1' LIMIT 1

110 (!!!!! 11930.227279663): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

111 (100.85105895996): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

112 (551.93901062012): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

113 (87.976455688477): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

114 (427.0076751709): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

115 (118.01719665527): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

116 (43.869018554688): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

117 (41.007995605469): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

118 (343.79959106445): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

119 (55.789947509766): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

120 (399.11270141602): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803027 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

121 (355.00526428223): SELECT name FROM jos_deeppockets WHERE id=214

122 (132.08389282227): SELECT name FROM jos_deeppockets WHERE id=214

123 (!!!!! 1435.9951019287): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))214((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

124 (881.91032409668): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))214((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

125 (168.0850982666): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803027 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803027 AND published='1' LIMIT 1

126 (607.01370239258): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803027 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803027 AND published='1' LIMIT 1

127 (!!!!! 17983.198165894): TRUNCATE TABLE jos_trademed_module

128 (!!!!! 3174.7817993164): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294803027 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

129 (!!!!! 1249.0749359131): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803027 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

130 (113.01040649414): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803027 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

131 (128.03077697754): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803027 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803027 AND published='1' LIMIT 1

132 (79.870223999023): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803027 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803027 AND published='1' LIMIT 1

133 (!!!!! 2305.0308227539): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

134 (113.01040649414): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803027 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803027 AND published='1' LIMIT 1

135 (78.201293945312): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803027 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803027 AND published='1' LIMIT 1

136 (72.956085205078): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294803027 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294803027 AND type='deeppockets_item' AND published='1' LIMIT 1

137 (51.975250244141): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=214 or channel_id is null)

138 (43.869018554688): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=214 or channel_id is null)

139 (107.0499420166): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

140 (796.07963562012): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803027 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803027 AND published='1' LIMIT 1

141 (70.810317993164): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294803027 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294803027 AND published='1' LIMIT 1

142 (93.936920166016): select jos_twitters.link from jos_twitters where cat=10

143 (56.028366088867): select jos_facebook.link from jos_facebook where cat=10

144 (61.988830566406): select jos_google_plus.link from jos_google_plus where cat=10

145 (42.915344238281): select jos_linkedin.link from jos_linkedin where cat=10

146 (!!!!! 1950.0255584717): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14202,14203)

147 (!!!!! 1821.9947814941): insert into jos_banners_delta values (14202,'2025-08-01 22:22:01','216.73.216.210','view'),(14203,'2025-08-01 22:22:01','216.73.216.210','view')

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