Download Mobile App

Video Library

Featured Links

Ultrasound Equipment
Trademed.com is our new marketplace where you will find ultrasound devices and equipment for hospitals and clinics.

Biodegradable Ultrasound Could Make Brain Cancers More Treatable

By MedImaging International staff writers
Posted on 15 Jun 2023

When a person is found to have a malignant brain tumor, the usual treatment is surgical removal followed by chemotherapy to eradicate any remaining cancer cells. However, brain cancers are notoriously resistant to chemotherapy, due to the blood-brain barrier, which is a protective membrane preventing large potentially harmful molecules from entering the brain. This same barrier also blocks beneficial chemo-drugs and other treatments from attacking brain cancer cells and treating other brain diseases. A safe and effective method of breaching the blood-brain barrier involves using ultrasound to vibrate cells sufficiently to create pores that allow the medication to pass through.

However, directing ultrasound through the thick human skull is challenging. Usually, numerous powerful ultrasound devices must be strategically positioned around the skull and accurately focused on the tumor's location with an MRI machine right after administering chemotherapy in a hospital setting. The procedure lasts about five to six hours and the intense ultrasound can damage tissues. The procedure is rarely conducted more than once, despite most patients with aggressive brain cancers undergoing chemotherapy for months. Utilizing ultrasound at each chemotherapy session would be significantly more effective. However, due to the complex nature of the MRI-ultrasound process, this is rarely done. Now, a revolutionary, biodegradable ultrasound, considerably more powerful than earlier models, could improve the treatment of brain cancers.

A device implanted directly in the brain can be used repeatedly to allow chemotherapy to permeate the brain and eliminate tumor cells. An implantable ultrasound device already exists in the market, but it's made of potentially toxic ceramic materials that require surgical removal post-treatment. Researchers at University of Connecticut (Storrs, CT, USA) had earlier built a safe, biodegradable piezoelectric ultrasound brain implant, although it wasn't as powerful as the traditional ceramic variants. In their latest research, the team employed a completely new method to create a biodegradable polymer ultrasound that is as powerful as ceramic models.

Initially, the researchers intended to use glycine crystals, an amino acid that's a common protein in the body and known for its strong piezoelectric properties. Glycine is safe and biodegradable, but it dissolves too quickly in water. Additionally, glycine piezoelectric crystals are brittle and shatter easily, which makes processing this material into a practical ultrasound device highly challenging. The researchers devised a unique solution: they grew glycine crystals, shattered them intentionally into pieces just a few hundred nanometers in size, and then spun them with polycaprolactone (PCL), a biodegradable polymer, to produce piezoelectric films composed of glycine and PCL nanofibers. These films can generate ultrasound at 334 kilo-Pascals under small voltage (~ 0.15 Vrms), similar to a ceramic ultrasound brain implant. They then coated the glycine-PCL film in other biodegradable polymers for protection. Poly-L-Lactide (PLLA), one potential coating, decomposes approximately in six weeks.

The researchers tested the device on mice with brain cancer, treating them with PTX (paclitaxel), a potent chemotherapy drug effective against brain cancer but difficult to pass through the blood-brain barrier. The glycine-PCL ultrasound successfully enabled PTX to cross the blood-brain barrier, reducing the tumors and doubling the lifespan of mice with brain cancer compared to those untreated. The combined treatment of glycine-PCL ultrasound and PTX was much more effective than using PTX alone, or PTX and ultrasound from the original, less powerful version of the biodegradable ultrasound device, based on PLLA. The team also conducted a six-month safety evaluation of the device implanted in the brain and found no negative impact on the health of the mice. The researchers now plan to test the safety and efficacy of the device in large animals.

Related Links:
University of Connecticut

Visit expo >

Gold Member

Ultrasound System

FUTUS LE

Gold Member

Electrode Solution and Skin Prep

Signaspray

Double Sided Apron

Maxima

Pencil Beam System

inus D DXA

Read the full article by registering today, it's FREE!

Free digital version edition of Medical Imaging International sent by email on regular basis
Free print version of Medical Imaging International magazine (available only outside USA and Canada).
Free and unlimited access to back issues of Medical Imaging International in digital format
Free Medical Imaging International Newsletter sent every week containing the latest news
Free breaking news sent via email
Free access to Events Calendar
Free access to LinkXpress new product services
REGISTRATION IS FREE AND EASY!

Sign in: Registered website members

Sign in: Registered magazine subscribers

Latest Ultrasound News

Channels

Radiography

view channel

3D Mammography Almost Halves Breast Cancer Incidence between Two Screening Tests

Breast cancer represents 28.9% of all cancers in women and is the primary cause of cancer-related deaths among this group. Interval breast cancers are those diagnosed in the period between two screening... Read more

MRI

view channel

Image: PET/MRI can accurately classify prostate cancer patients (Photo courtesy of 123RF)

PET/MRI Improves Diagnostic Accuracy for Prostate Cancer Patients

The Prostate Imaging Reporting and Data System (PI-RADS) is a five-point scale to assess potential prostate cancer in MR images. PI-RADS category 3 which offers an unclear suggestion of clinically significant... Read more

Next Generation MR-Guided Focused Ultrasound Ushers In Future of Incisionless Neurosurgery

Essential tremor, often called familial, idiopathic, or benign tremor, leads to uncontrollable shaking that significantly affects a person’s life. When traditional medications do not alleviate symptoms,... Read more

Image: Shorter scan to diagnose prostate cancer can increase availability and reduce cost (Photo courtesy of 123RF)

Two-Part MRI Scan Detects Prostate Cancer More Quickly without Compromising Diagnostic Quality

Prostate cancer ranks as the most prevalent cancer among men. Over the last decade, the introduction of MRI scans has significantly transformed the diagnosis process, marking the most substantial advancement... Read more

World’s Most Powerful MRI Machine Images Living Brain with Unrivaled Clarity

The world's most powerful magnetic resonance imaging (MRI) scanner has generated its first images of the human brain, demonstrating new precision levels that could shed more light on the mysterious human... Read more

Nuclear Medicine

view channel

New SPECT/CT Technique Could Change Imaging Practices and Increase Patient Access

The development of lead-212 (212Pb)-PSMA–based targeted alpha therapy (TAT) is garnering significant interest in treating patients with metastatic castration-resistant prostate cancer. The imaging of 212Pb,... Read more

New Radiotheranostic System Detects and Treats Ovarian Cancer Noninvasively

Ovarian cancer is the most lethal gynecological cancer, with less than a 30% five-year survival rate for those diagnosed in late stages. Despite surgery and platinum-based chemotherapy being the standard... Read more

AI System Automatically and Reliably Detects Cardiac Amyloidosis Using Scintigraphy Imaging

Cardiac amyloidosis, a condition characterized by the buildup of abnormal protein deposits (amyloids) in the heart muscle, severely affects heart function and can lead to heart failure or death without... Read more

Early 30-Minute Dynamic FDG-PET Acquisition Could Halve Lung Scan Times

F-18 FDG-PET scans are a way to look inside the body using a special dye, and these scans can be either static or dynamic. Static scans happen 60 minutes after the dye is administered into the body, showing... Read more

General/Advanced Imaging

view channel

Image: The Tyche machine-learning model could help capture crucial information. (Photo courtesy of 123RF)

New AI Method Captures Uncertainty in Medical Images

In the field of biomedicine, segmentation is the process of annotating pixels from an important structure in medical images, such as organs or cells. Artificial Intelligence (AI) models are utilized to... Read more

CT Coronary Angiography Reduces Need for Invasive Tests to Diagnose Coronary Artery Disease

Coronary artery disease (CAD), one of the leading causes of death worldwide, involves the narrowing of coronary arteries due to atherosclerosis, resulting in insufficient blood flow to the heart muscle.... Read more

$Image: An amyloid blood test can help identify patients who may forgo imaging evaluation for Alzheimer\'s disease (Photo courtesy of 123RF)$

Novel Blood Test Could Reduce Need for PET Imaging of Patients with Alzheimer’s

Alzheimer's disease (AD), a condition marked by cognitive decline and the presence of beta-amyloid (Aβ) plaques and neurofibrillary tangles in the brain, poses diagnostic challenges. Amyloid positron emission... Read more

CT-Based Deep Learning Algorithm Accurately Differentiates Benign From Malignant Vertebral Fractures

The rise in the aging population is expected to result in a corresponding increase in the prevalence of vertebral fractures which can cause back pain or neurologic compromise, leading to impaired function... Read more

Imaging IT

view channel

New Google Cloud Medical Imaging Suite Makes Imaging Healthcare Data More Accessible

Medical imaging is a critical tool used to diagnose patients, and there are billions of medical images scanned globally each year. Imaging data accounts for about 90% of all healthcare data1 and, until... Read more

Global AI in Medical Diagnostics Market to Be Driven by Demand for Image Recognition in Radiology

The global artificial intelligence (AI) in medical diagnostics market is expanding with early disease detection being one of its key applications and image recognition becoming a compelling consumer proposition... Read more

AI-Based Mammography Triage Software Helps Dramatically Improve Interpretation Process

An artificial intelligence (AI)-based mammography triage software is helping dramatically improve the interpretation process for healthcare providers. In a new study, researchers at the Scripps Green... Read more

Artificial Intelligence (AI) Program Accurately Predicts Lung Cancer Risk from CT Images

An artificial intelligence (AI) program accurately predicts the risk that lung nodules detected on screening CT will become cancerous, according to a study published in the journal Radiology.... Read more

Industry News

view channel

Bayer and Google Partner on New AI Product for Radiologists

Medical imaging data comprises around 90% of all healthcare data, and it is a highly complex and rich clinical data modality and serves as a vital tool for diagnosing patients. Each year, billions of medical... Read more

Image: Samsung Medison CEO Mr. Yongkwan Kim and Bracco Imaging CEO Dr. Fulvio Renoldi Bracco endorsed a MoU agreement (Photo courtesy of Bracco Group)

Samsung and Bracco Enter Into New Diagnostic Ultrasound Technology Agreement

Samsung Medison (Seoul, South Korea) and Bracco Imaging (Milan, Italy) have entered into a Memorandum of Understanding (MoU) agreement to pioneer a new area for diagnostic ultrasound devices and contrast agents.... Read more

Image: The acquisition will expand IBA’s medical imaging quality assurance offering (Photo courtesy of Radcal)

IBA Acquires Radcal to Expand Medical Imaging Quality Assurance Offering

Ion Beam Applications S.A. (IBA, Louvain-La-Neuve, Belgium), the global leader in particle accelerator technology and a world-leading provider of dosimetry and quality assurance (QA) solutions, has entered... Read more

International Societies Suggest Key Considerations for AI Radiology Tools

Artificial intelligence (AI) holds the potential to significantly disrupt the field of radiology, presenting both opportunities and challenges. Its integration could transform healthcare by enhancing the... Read more

1 (88.930130004883): SET sql_mode = 'MYSQL40'

2 (144.95849609375): SELECT folder, element, published, params FROM jos_mambots WHERE published >= 1 AND access <= 0 AND folder = 'system' ORDER BY ordering

3 (426.05400085449): SELECT template FROM jos_templates_menu WHERE client_id = 0 AND ( menuid = 0 OR menuid = 294797574 ) ORDER BY menuid DESC LIMIT 1

4 (321.1498260498): DELETE FROM jos_session WHERE time < 1745998961 AND guest = 1 AND userid = 0

5 (65.803527832031): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

6 (!!!!! 4452.9438018799): SELECT * FROM jos_session WHERE session_id = 'a3a45cc615260f5e3375e835deeb9b21'

7 (453.94897460938): UPDATE jos_session SET `time`='1745999861',`userid`='0',`usertype`='\'\'',`username`='',`gid`='0',`guest`='1' WHERE session_id='a3a45cc615260f5e3375e835deeb9b21'

8 (361.91940307617): SELECT * FROM jos_menu WHERE id = 294797574

9 (698.08959960938): SELECT dp.*, ch.title as channel, ch.name as channel_name, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 #AND dp.cat=10 AND dp.id=294797574 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

10 (727.89192199707): SELECT dp.*, ch.title as channel, ch.name as channel_name, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 #AND dp.cat=10 AND dp.id=294797574 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

11 (87.976455688477): SELECT dp.*, ch.title as channel, ch.name as channel_name, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 #AND dp.cat=10 AND dp.id=294797574 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

12 (!!!!! 1336.0977172852): SELECT * FROM jos_deeppockets WHERE 1=1 AND cat=10 AND type='deeppockets_item' AND published='1' AND (id<>294797574) AND (fid=214) ORDER BY id DESC, `created` DESC LIMIT 0,16

13 (180.95970153809): SELECT * FROM jos_deeppockets WHERE 1=1 AND cat=10 AND type='deeppockets_item' AND published='1' AND (id<>294797574) AND (fid=214) ORDER BY id DESC, `created` DESC LIMIT 0,16

14 (!!!!! 4860.1627349854): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='P' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_item.fid=214 and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) AND (jos_number.channelID=294797574 OR jos_number.channelID=0) ORDER BY RAND() DESC LIMIT 3

15 (!!!!! 13043.165206909): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='P' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_item.fid=214 and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) AND (jos_number.channelID=294797574 OR jos_number.channelID=0) ORDER BY RAND() DESC LIMIT 3

16 (!!!!! 4870.8915710449): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='P' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) AND (jos_number.channelID=294797574 OR jos_number.channelID=0) ORDER BY RAND() DESC LIMIT 3

17 (!!!!! 6125.9269714355): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='P' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) AND (jos_number.channelID=294797574 OR jos_number.channelID=0) ORDER BY RAND() DESC LIMIT 3

18 (514.03045654297): SELECT name,id,title FROM jos_deeppockets WHERE id=214 LIMIT 1

19 (60.081481933594): SELECT name,id,title FROM jos_deeppockets WHERE id=214 LIMIT 1

20 (666.85676574707): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294797574 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

21 (634.90867614746): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294797574 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

22 (118.01719665527): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294797574 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

23 (90.122222900391): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294797574 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

24 (706.91108703613): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294797574 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

25 (!!!!! 2972.1260070801): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294797574 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

26 (101.80473327637): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294797574 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

27 (82.015991210938): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294797574 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

28 (88.930130004883): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294797574 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

29 (76.055526733398): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294797574 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

30 (144.00482177734): SELECT conference_items.channel_id, conference_items.tracking_code FROM conference_items LEFT JOIN conference_groups ON conference_groups.id = conference_items.group_id LEFT JOIN jos_deeppockets ON jos_deeppockets.id = conference_items.channel_id LEFT JOIN jos_journal ON jos_journal.cat = jos_deeppockets.cat AND jos_journal.real = 1 AND jos_journal.directory IS NOT NULL WHERE 1 = 1 ORDER BY conference_items.id

31 (!!!!! 6433.9637756348): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294797574 LIMIT 1

32 (!!!!! 3376.0070800781): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294797574 LIMIT 1

33 (563.14468383789): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294797574 LIMIT 1

34 (62.942504882812): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294797574 LIMIT 1

35 (!!!!! 9678.840637207): SELECT * FROM jos_bannersmanager_banner WHERE `groupid` = 98 AND `site_id` = 10 AND `published` = 1

36 (!!!!! 4941.2250518799): SELECT * FROM jos_bannersmanager_banner WHERE `groupid` = 99 AND `site_id` = 10 AND `published` = 1

37 (!!!!! 23518.800735474): SELECT id, title, module, position, content, showtitle, params FROM jos_modules AS m INNER JOIN jos_modules_menu AS mm ON mm.moduleid = m.id WHERE m.published = 1 AND m.access <= 0 AND m.client_id != 1 AND ( mm.menuid = 0 OR mm.menuid = 294797574 ) ORDER BY ordering

38 (!!!!! 3595.1137542725): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

39 (138.0443572998): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

40 (62.227249145508): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294797574 LIMIT 1

41 (41.961669921875): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294797574 LIMIT 1

42 (39.815902709961): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294797574 LIMIT 1

43 (36.001205444336): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294797574 LIMIT 1

44 (36.001205444336): select journal.name,journal.id,dpcat.livesite,journal.code from jos_dp_categories dpcat join jos_journal journal on journal.id=dpcat.journalid where dpcat.id=10

45 (118.01719665527): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

46 (101.08947753906): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

47 (160.93254089355): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

48 (147.81951904297): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

49 (127.07710266113): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

50 (!!!!! 6605.1483154297): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

51 (!!!!! 3040.075302124): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

52 (114.91775512695): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

53 (709.05685424805): SELECT name FROM jos_deeppockets WHERE id=294797574 LIMIT 1

54 (745.05805969238): SELECT name FROM jos_deeppockets_archive WHERE id=294797574 LIMIT 1

55 (145.91217041016): SELECT a.* FROM jos_components AS a WHERE ( a.admin_menu_link = 'option=com_syndicate' OR a.admin_menu_link = 'option=com_syndicate&hidemainmenu=1' ) AND a.option = 'com_syndicate'

56 (66.995620727539): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294797574 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

57 (979.90036010742): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294797574 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

58 (!!!!! 11385.202407837): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

59 (!!!!! 7906.1985015869): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

60 (!!!!! 5508.1844329834): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

61 (!!!!! 1575.9468078613): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

62 (123.97766113281): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

63 (553.84635925293): SELECT fid FROM jos_deeppockets WHERE id=294797574 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294797574 AND published='1' LIMIT 1

64 (311.85150146484): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=214 ORDER BY `ordering`

65 (104.18891906738): select jos_twitters.link from jos_twitters where cat=10

66 (44.107437133789): select jos_facebook.link from jos_facebook where cat=10

67 (36.001205444336): select jos_google_plus.link from jos_google_plus where cat=10

68 (32.186508178711): select jos_linkedin.link from jos_linkedin where cat=10

69 (41.961669921875): SELECT fid FROM jos_deeppockets WHERE id=294797574 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294797574 AND published='1' LIMIT 1

70 (37.908554077148): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=214 ORDER BY `ordering`

71 (249.14741516113): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294797574 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (349.04479980469): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294797574 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

73 (72.956085205078): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

74 (107.0499420166): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (33.855438232422): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (56.028366088867): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (63.180923461914): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294797574 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (41.961669921875): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294797574 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

90 (33.855438232422): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

91 (118.01719665527): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (46.968460083008): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (209.09309387207): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (!!!!! 2995.0141906738): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (!!!!! 7611.9899749756): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (!!!!! 3764.1525268555): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (!!!!! 3343.1053161621): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (!!!!! 1177.0725250244): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (959.15794372559): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (308.99047851562): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (654.93583679199): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (!!!!! 2038.0020141602): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (524.99771118164): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (67.949295043945): SELECT show_live FROM jos_com_show_setting LIMIT 1

105 (!!!!! 1368.0458068848): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

106 (89.883804321289): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

107 (322.10350036621): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294797574 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (730.03768920898): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294797574 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

109 (!!!!! 2337.9325866699): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

110 (97.990036010742): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

111 (172.85346984863): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294797574 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (!!!!! 1240.9687042236): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294797574 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

113 (!!!!! 2830.982208252): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (!!!!! 3855.9436798096): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

115 (!!!!! 8265.0184631348): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

116 (154.01840209961): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

117 (!!!!! 1488.9240264893): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

118 (810.14633178711): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

119 (!!!!! 3255.8441162109): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

120 (888.10920715332): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

121 (!!!!! 4154.9205780029): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

122 (!!!!! 60119.152069092): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

123 (!!!!! 2379.8942565918): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

124 (!!!!! 1668.9300537109): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

125 (!!!!! 5281.925201416): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294797574 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294797574 AND type='deeppockets_item' AND published='1' LIMIT 1

126 (!!!!! 1717339.9925232): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (!!!!! 1951487.0643616): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

128 (963.21105957031): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

129 (74.863433837891): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

130 (664.94941711426): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

131 (340.93856811523): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

132 (604.86793518066): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

133 (45.061111450195): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

134 (329.01763916016): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

135 (310.89782714844): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (159.02519226074): SELECT name FROM jos_deeppockets WHERE id=214

137 (97.990036010742): SELECT name FROM jos_deeppockets WHERE id=214

138 (719.07043457031): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))214((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

139 (576.01928710938): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))214((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (!!!!! 9361.0286712646): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

141 (209.09309387207): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

142 (!!!!! 8052.1106719971): TRUNCATE TABLE jos_trademed_module

143 (799.89433288574): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294797574 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

144 (590.08598327637): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294797574 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (491.14227294922): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

146 (67.949295043945): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (77.009201049805): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

148 (55.074691772461): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

149 (!!!!! 1541.1376953125): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

150 (675.91667175293): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

151 (126.12342834473): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

152 (!!!!! 2681.9705963135): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294797574 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294797574 AND type='deeppockets_item' AND published='1' LIMIT 1

153 (!!!!! 1760.0059509277): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=214 or channel_id is null)

154 (211.00044250488): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=214 or channel_id is null)

155 (107.0499420166): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

156 (218.15299987793): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

157 (107.0499420166): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797574 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797574 AND published='1' LIMIT 1

158 (158.07151794434): select jos_twitters.link from jos_twitters where cat=10

159 (66.041946411133): select jos_facebook.link from jos_facebook where cat=10

160 (40.054321289062): select jos_google_plus.link from jos_google_plus where cat=10

161 (36.001205444336): select jos_linkedin.link from jos_linkedin where cat=10

162 (495.91064453125): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

163 (!!!!! 1304.1496276855): insert into jos_banners_delta values (14615,'2025-04-30 07:57:47','3.145.152.98','view'),(14202,'2025-04-30 07:57:47','3.145.152.98','view'),(14203,'2025-04-30 07:57:47','3.145.152.98','view')

Click for LinkXpress Reader Inquiry Service
Enter code to receive information:

Where I can find code?

LinkXpress

Download Mobile App

Video Library

Featured Links

Biodegradable Ultrasound Could Make Brain Cancers More Treatable

Latest Ultrasound News

Channels

MedImaging

Channels

Features

Partner Sites

Archive: