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3D Printed Heart Models Could Enable Non-Invasive Diagnosis of Aortic Stenosis

By MedImaging International staff writers
Posted on 11 Apr 2023

Image: Researchers have made advances in efforts to deploy 3D printed heart models (phantoms) to simulate and study aortic stenosis (Photo courtesy of KCL)

Aortic stenosis is a condition characterized by calcified and thickened aortic heart valves, which impede blood flow. Existing methods for assessing the severity of aortic stenosis, like Doppler echocardiography, can be prone to uncontrolled errors and often necessitate invasive pressure measurements for patients. No, aortic flow phantoms could provide a potential solution to this issue.

Researchers at King’s College London (KCL, London, UK) have made progress in utilizing 3D printed heart models (phantoms) to simulate and investigate aortic stenosis. Computer modeling and 3D printing of aortic flow phantoms present an alternative to in vivo studies, which are associated with challenges in patient recruitment and potential procedural risks. In contrast, the simulated option allows for greater variations in blood pressure flow and drop. The researchers created a non-invasive technique for evaluating pressure recovery distance based on blood flow momentum using 4D Flow cardiovascular magnetic resonance (CMR). Their findings revealed that pressure recovery distances in aortic stenosis are longer than previously recognized, indicating a need to reevaluate currently adopted interventional practices.

Furthermore, the researchers developed and successfully tested a flow phantom compatible with MRI and ultrasound, which accurately simulates valve opening and closing in both healthy and diseased conditions and offers ground-truth pressure measurement. The team's findings suggest that the peak-to-peak pressure drop, a current metric for assessing the burden of aortic stenosis, may be influenced by factors unrelated to the valve, such as wave reflection, and should be reexamined in clinical practice.

“By developing valve models that behave like real human valves, new techniques which more accurately characterize the severity of disease can be developed and improved without disrupting patients' care,” said Harminder Gill, BM BCh.

“The decision on how and when to treat stenotic valves is complex and the diagnostic tools typically used in clinical routine have barely evolved during the past 50 years,” explained Joao Filipe Fernandes, PhD, Marie Skłodowska-Curie Early Stage Researcher in Personalized in-Silico Cardiology. “Thus, advances in the study of aortic stenosis patho-physiology are essential to provide a more comprehensive characterization of this condition. The non-invasive assessment of the pressure recovery distance allows the detection of invasive catheterization errors as well as understanding the vessel length required for hemodynamic homeostasis to be reached.”

“These advances will enable us to take well informed decision on the best balance between drugs and surgeries for people living with valve conditions,” added Prof. Pablo Lamata, Head of Cardiac Modeling and Imaging Biomarkers Group.

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66 (!!!!! 7644.8917388916): select jos_twitters.link from jos_twitters where cat=10

67 (!!!!! 4992.9618835449): select jos_facebook.link from jos_facebook where cat=10

68 (!!!!! 6534.0995788574): select jos_google_plus.link from jos_google_plus where cat=10

69 (!!!!! 8627.17628479): select jos_linkedin.link from jos_linkedin where cat=10

70 (!!!!! 1348.9723205566): SELECT fid FROM jos_deeppockets WHERE id=294796804 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294796804 AND published='1' LIMIT 1

71 (!!!!! 2195.8351135254): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=214 ORDER BY `ordering`

72 (!!!!! 7791.0423278809): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294796804 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

73 (!!!!! 7936.0008239746): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294796804 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

74 (!!!!! 7930.9940338135): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

75 (!!!!! 5213.9759063721): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (!!!!! 10917.901992798): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (!!!!! 11752.128601074): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (!!!!! 5256.175994873): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (!!!!! 8123.8746643066): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (!!!!! 3450.1552581787): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (!!!!! 8884.9067687988): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (!!!!! 8069.0383911133): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (!!!!! 7516.1457061768): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (!!!!! 8838.8919830322): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (!!!!! 7367.8493499756): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (!!!!! 7972.0020294189): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (!!!!! 7847.0706939697): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (!!!!! 7985.1150512695): SELECT show_live FROM jos_com_show_setting LIMIT 1

89 (!!!!! 9197.9503631592): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294796804 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

90 (!!!!! 4686.8324279785): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294796804 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

91 (!!!!! 11163.949966431): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

92 (55.074691772461): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (29.802322387695): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (24.795532226562): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (52.928924560547): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (51.021575927734): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (81.062316894531): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (257.01522827148): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (49.114227294922): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (96.08268737793): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (56.028366088867): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (277.04238891602): SELECT show_live FROM jos_com_show_setting LIMIT 1

105 (121.11663818359): SELECT show_live FROM jos_com_show_setting LIMIT 1

106 (562.90626525879): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796804 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796804 AND published='1' LIMIT 1

107 (177.14500427246): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796804 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796804 AND published='1' LIMIT 1

108 (!!!!! 4891.8724060059): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294796804 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

109 (!!!!! 1027.1072387695): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294796804 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

110 (!!!!! 4415.9889221191): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796804 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796804 AND published='1' LIMIT 1

111 (!!!!! 2218.9617156982): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796804 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796804 AND published='1' LIMIT 1

112 (771.04568481445): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294796804 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

113 (!!!!! 5285.9783172607): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294796804 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

114 (!!!!! 3998.9948272705): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294796798 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

115 (!!!!! 18440.961837769): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294796798 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

116 (!!!!! 15796.899795532): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

117 (!!!!! 7969.1410064697): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

118 (!!!!! 12087.106704712): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796804 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796804 AND published='1' LIMIT 1

119 (!!!!! 7728.099822998): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796804 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796804 AND published='1' LIMIT 1

120 (!!!!! 7748.1269836426): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796804 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796804 AND published='1' LIMIT 1

121 (!!!!! 7971.0483551025): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796804 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796804 AND published='1' LIMIT 1

122 (!!!!! 7515.1920318604): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796804 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796804 AND published='1' LIMIT 1

123 (868.08204650879): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796804 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796804 AND published='1' LIMIT 1

124 (!!!!! 2287.8646850586): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

125 (!!!!! 126179.93354797): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

126 (96.08268737793): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796804 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796804 AND published='1' LIMIT 1

127 (56.028366088867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796804 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796804 AND published='1' LIMIT 1

128 (455.85632324219): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294796804 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294796804 AND type='deeppockets_item' AND published='1' LIMIT 1

129 (!!!!! 1278450.012207): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

130 (!!!!! 2063.9896392822): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

131 (!!!!! 2648.8304138184): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

132 (!!!!! 7179.0218353271): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

133 (541.92543029785): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

134 (!!!!! 1007.7953338623): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

135 (297.06954956055): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

136 (715.97099304199): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

137 (854.9690246582): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796804 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

138 (673.05564880371): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796804 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

139 (!!!!! 4566.1926269531): SELECT name FROM jos_deeppockets WHERE id=214

140 (!!!!! 1917.1237945557): SELECT name FROM jos_deeppockets WHERE id=214

141 (!!!!! 1425.02784729): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))214((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

142 (!!!!! 1196.8612670898): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))214((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

143 (!!!!! 3901.0047912598): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796804 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796804 AND published='1' LIMIT 1

144 (!!!!! 3212.9287719727): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796804 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796804 AND published='1' LIMIT 1

145 (!!!!! 13782.978057861): TRUNCATE TABLE jos_trademed_module

146 (!!!!! 6693.8400268555): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294796804 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

147 (!!!!! 1553.0586242676): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294796804 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

148 (!!!!! 1873.9700317383): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796804 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

149 (!!!!! 4215.0020599365): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796804 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

150 (!!!!! 1220.2262878418): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796804 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796804 AND published='1' LIMIT 1

151 (590.08598327637): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796804 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796804 AND published='1' LIMIT 1

152 (!!!!! 2372.9801177979): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

153 (!!!!! 1456.0222625732): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796804 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796804 AND published='1' LIMIT 1

154 (!!!!! 4001.8558502197): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796804 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796804 AND published='1' LIMIT 1

155 (!!!!! 1442.9092407227): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294796804 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294796804 AND type='deeppockets_item' AND published='1' LIMIT 1

156 (!!!!! 1807.9280853271): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=0 or channel_id is null)

157 (339.98489379883): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=0 or channel_id is null)

158 (845.90911865234): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

159 (!!!!! 6392.9557800293): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796804 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796804 AND published='1' LIMIT 1

160 (291.10908508301): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294796804 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294796804 AND published='1' LIMIT 1

161 (43.153762817383): select jos_twitters.link from jos_twitters where cat=10

162 (31.948089599609): select jos_facebook.link from jos_facebook where cat=10

163 (42.915344238281): select jos_google_plus.link from jos_google_plus where cat=10

164 (26.941299438477): select jos_linkedin.link from jos_linkedin where cat=10

165 (980.13877868652): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

166 (!!!!! 12105.941772461): insert into jos_banners_delta values (14615,'2025-04-30 07:02:12','3.16.160.142','view'),(14202,'2025-04-30 07:02:12','3.16.160.142','view'),(14203,'2025-04-30 07:02:12','3.16.160.142','view')

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