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Norwegian Research Center Provides Insights into Heart Defects in Newborns

By MedImaging International staff writers
Posted on 30 Mar 2011

A Norwegian medical research laboratory is making advances in imaging techniques for both ultrasound and magnetic resonance imaging (MRI). More...

One benefit will be an enhanced ability to better identify heart defects in newborns.

"Making the correct diagnosis is the greatest challenge facing pediatric cardiologists," explained Dr. Siri-Ann Nyrnes, consultant in the pediatric department of St. Olav's Hospital Trondheim University Hospital (Norway). "The organs are so small, and current ultrasound imaging can only provide limited information. A cardiologist needs many years of experience to be able to make a diagnosis with any certainty." Dr. Nyrnes is part of the Medical Imaging Laboratory (MI Lab; Trondheim, Norway), whose host institution is the Norwegian University of Science and Technology (NTNU).

MI Lab is one of Norway's 14 original Centers for Research-based Innovation (SFI), which have received funding from the Research Council of Norway since 2007. Color Doppler imaging has been the standard in ultrasound since the late 1980s. MI Lab's new method, called blood flow imaging (BFI), provides two-dimensional blood flow information by visualizing blood speckle movement superimposed on color Doppler images. The resulting pattern displays blood flow regardless of the ultrasound beam orientation providing greater information about flow direction as well as a more intuitive visualization. Blood flow rate can also be measured, and clinicians will soon be able to determine the actual volume of blood flowing through normal and pathologic openings.
In a pilot study, researchers examined 13 children with ventricular septal defect (a hole in the wall between the right and left ventricles of the heart, the most common heart defect in newborns). Using both new and traditional blood flow imaging methods, the researchers concluded that compared to the color Doppler, the new method provides a significantly more detailed image of blood flow.

"The images in this study were created by the physician and technician working together, so the latter could see first-hand what we physicians are contending with, and what we need in order to improve our diagnostics," remarked Dr. Nyrnes. "The method is being refined with each patient."

The MI Lab is now taking the method an additional step by using plane wave imaging, which can generate an image more quickly. A pilot study of five newborns indicated that plane wave imaging yielded 5-10 times more images per second, with a considerably higher image quality.

"Quantifying the blood flow is our next objective," said engineer and research fellow Lasse Løvstakken. "Ultimately we want to develop this method to provide blood flow information in 3D [three-dimensions]."

Olav Haraldseth, a professor of medicine at NTNU, is also the director of MI Lab. "We are focusing our research on ultrasound and MR because these will most likely be the most important methods in future healthcare," he asserted.

The goal of MI Lab is to establish a major interdisciplinary research group involving relevant participants from the entire research community in the Trondheim area. The group is to integrate fields such as medicine, ICT [information and communication technology], physics, mathematics, cybernetics, electronics, physiology, molecular biology, neuroscience, and psychology. "I believe that this collaborative effort between the university, hospital, and industry will prove very fruitful, yielding high-quality research and innovation that are useful to our industry partners and to society as a whole. Our objective must be to encourage medical research that makes Norwegian industry more competitive. Medicine is a knowledge-based industry, and the whole world is our market," said Prof. Haraldseth.

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57 (624.17984008789): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294734190 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

58 (!!!!! 1594.066619873): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734190 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734190 AND published='1' LIMIT 1

59 (72.002410888672): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734190 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734190 AND published='1' LIMIT 1

60 (144.00482177734): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734190 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734190 AND published='1' LIMIT 1

61 (65.088272094727): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734190 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734190 AND published='1' LIMIT 1

62 (84.877014160156): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

63 (625.1335144043): SELECT fid FROM jos_deeppockets WHERE id=294734190 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294734190 AND published='1' LIMIT 1

64 (51.975250244141): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=214 ORDER BY `ordering`

65 (46.968460083008): select jos_twitters.link from jos_twitters where cat=10

66 (32.901763916016): select jos_facebook.link from jos_facebook where cat=10

67 (36.954879760742): select jos_google_plus.link from jos_google_plus where cat=10

68 (36.001205444336): select jos_linkedin.link from jos_linkedin where cat=10

69 (35.04753112793): SELECT fid FROM jos_deeppockets WHERE id=294734190 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294734190 AND published='1' LIMIT 1

70 (35.04753112793): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=214 ORDER BY `ordering`

71 (327.82554626465): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294734190 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (247.00164794922): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294734190 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

73 (91.075897216797): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

74 (71.048736572266): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (34.093856811523): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (32.186508178711): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (31.232833862305): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (31.232833862305): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (66.995620727539): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294734190 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (34.809112548828): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294734190 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

90 (36.954879760742): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

91 (56.982040405273): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (33.855438232422): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (38.14697265625): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (63.896179199219): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (46.014785766602): SELECT show_live FROM jos_com_show_setting LIMIT 1

105 (104.90417480469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734190 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734190 AND published='1' LIMIT 1

106 (61.03515625): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734190 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734190 AND published='1' LIMIT 1

107 (83.92333984375): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294734190 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (58.174133300781): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294734190 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

109 (113.01040649414): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734190 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734190 AND published='1' LIMIT 1

110 (72.956085205078): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734190 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734190 AND published='1' LIMIT 1

111 (54.836273193359): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294734190 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (566.00570678711): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294734190 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

113 (644.92225646973): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (377.17819213867): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

115 (87.02278137207): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734190 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734190 AND published='1' LIMIT 1

116 (51.021575927734): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734190 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734190 AND published='1' LIMIT 1

117 (53.167343139648): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734190 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734190 AND published='1' LIMIT 1

118 (44.822692871094): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734190 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734190 AND published='1' LIMIT 1

119 (124.93133544922): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734190 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734190 AND published='1' LIMIT 1

120 (44.822692871094): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734190 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734190 AND published='1' LIMIT 1

121 (48.87580871582): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734190 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734190 AND published='1' LIMIT 1

122 (39.100646972656): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734190 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734190 AND published='1' LIMIT 1

123 (465.15464782715): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

124 (!!!!! 24662.017822266): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

125 (764.13154602051): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294734190 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294734190 AND type='deeppockets_item' AND published='1' LIMIT 1

126 (!!!!! 9336.9483947754): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (104.90417480469): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

128 (46.014785766602): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (34.809112548828): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

130 (47.922134399414): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (32.186508178711): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

132 (560.99891662598): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (53.882598876953): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

134 (38.862228393555): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (32.901763916016): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

136 (481.84394836426): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734190 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (404.11949157715): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734190 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

138 (46.014785766602): SELECT name FROM jos_deeppockets WHERE id=214

139 (51.975250244141): SELECT name FROM jos_deeppockets WHERE id=214

140 (616.07360839844): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))214((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (558.13789367676): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))214((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

142 (69.856643676758): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734190 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734190 AND published='1' LIMIT 1

143 (48.160552978516): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734190 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734190 AND published='1' LIMIT 1

144 (!!!!! 8726.8352508545): TRUNCATE TABLE jos_trademed_module

145 (243.9022064209): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294734190 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (131.84547424316): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294734190 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

147 (959.87319946289): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734190 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (62.942504882812): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734190 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

149 (98.943710327148): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734190 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734190 AND published='1' LIMIT 1

150 (76.055526733398): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734190 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734190 AND published='1' LIMIT 1

151 (!!!!! 1703.9775848389): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

152 (84.161758422852): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734190 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734190 AND published='1' LIMIT 1

153 (60.081481933594): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734190 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734190 AND published='1' LIMIT 1

154 (54.121017456055): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294734190 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294734190 AND type='deeppockets_item' AND published='1' LIMIT 1

155 (44.822692871094): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=214 or channel_id is null)

156 (39.100646972656): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=214 or channel_id is null)

157 (50.067901611328): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

158 (93.936920166016): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734190 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734190 AND published='1' LIMIT 1

159 (65.803527832031): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294734190 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294734190 AND published='1' LIMIT 1

160 (77.009201049805): select jos_twitters.link from jos_twitters where cat=10

161 (47.922134399414): select jos_facebook.link from jos_facebook where cat=10

162 (47.922134399414): select jos_google_plus.link from jos_google_plus where cat=10

163 (36.954879760742): select jos_linkedin.link from jos_linkedin where cat=10

164 (427.9613494873): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14202,14203)

165 (!!!!! 1114.8452758789): insert into jos_banners_delta values (14202,'2025-08-12 15:40:20','216.73.216.186','view'),(14203,'2025-08-12 15:40:20','216.73.216.186','view')

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