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3D Ultrasound Used with Breast Cancer Treatment Planning Better Defines Treatment Region

By MedImaging International staff writers
Posted on 02 Apr 2009

Researchers report that the use of three-dimensional (3D) ultrasound provided enhanced image information to enable radiation oncologists to better define the treatment region when delivering partial breast irradiation treatment (PBI) for breast cancer.

The Clarity breast system marks the first application of 3D ultrasound technology to image-guided radiation therapy (IGRT). The system was developed by Resonant Medical Montreal, Canada), an innovator of 3D ultrasound image-guided adaptive radiotherapy products. The study was published in the February 1, 2009, issue of the International Journal of Radiation Oncology Biology Physics.

The study, conducted at the Radiation Therapy Program, British Columbia Cancer Agency, Vancouver Island Center (Canada) and the University of British Columbia (Vancouver, Canada), examined 20 consecutive cases of early-stage breast cancer where the patients were treated with breast-conserving surgery. Researchers found that in 40% of cases, the variability between lumpectomy cavity contours was reduced when ultrasound was used instead of computed tomography (CT) imaging--the current standard of care for planning breast cancer treatment. Specifically, 3D ultrasound proved to be particularly beneficial for imaging patients with dense breasts and small cavities.

"Precision in planning and the increased certainty that radiation is being delivered to the exact area where it is needed have never been more critical, with the percentage of patients opting for breast conservation therapy and PBI on the rise," said Pauline Truong, M.D., C.M., a researcher on the study. "Following this study, however, it is clear that the benefits of this technology could be applicable to not only PBI patients, but those undergoing whole breast radiation and electron boost therapy--potentially helping an even larger population of women with breast cancer."

The Clarity system was approved by the U.S. Food and Drug Administration (FDA) in 2004 for guidance in the treatment of prostate and breast cancers. In addition to its application with treatment planning, the Clarity system is also used to image the lumpectomy cavity daily with each radiation treatment, to get an actual visual image and location of the tumor cavity on a regular basis. While the breast cancer radiation oncology community is aware that the location of the lumpectomy cavity target can change throughout the course of treatment, this issue is still largely unaccounted for in current treatment protocols.

Clinical consequences can include delivery of radiation to healthy tissue, application of radiation too close to the chest wall or skin, and in some instances, under-treatment of certain areas. Clarity provides the first method of daily lumpectomy cavity monitoring that is based on visualization of the actual anatomy--rather than an estimation of the location of the cavity. This precision in planning and treatment could enable physicians to reduce the field of radiation they need to deliver, which is always preferable if clinically justified.

Several studies detailing the benefits of the use of Clarity during breast cancer treatment have also been presented in recent months. For example, data from a study conducted at McGill University (Montreal, Canada) and the University of Vermont (Burlington, VT, USA) was presented investigating the use of the Clarity system to track tumor cavity movement prior to daily treatments. The study compared the use of 3D ultrasound to CT, and found that these techniques were statistically equivalent. Researchers concluded that because ultrasound is non-ionizing and noninvasive, it is preferable to daily CT for tumor cavity monitoring.

Moreover, at the 2008 meeting of the Radiological Society of North America (RSNA) in Chicago, IL, USA, data collected at Beth Israel Medical Center (New York, NY, USA) on the use of Clarity when delivering electron boost therapy was examined. Although electron boost treatments have been delivered for quite a while, there has been no way to ensure that the electron dose is treating the correct area. This study found that in 45% of treatments, part of the tumor cavity would have been outside of the dose region and would have been missed without ultrasound guidance.

"The Clarity system has been used in the treatment of thousands of prostate cancer patients, and we are encouraged by the results and feedback we have seen and heard from radiation oncologists regarding its application with breast cancer," said Tony Falco, Ph.D., FCCP, founder and chief executive officer of Resonant Medical. "This mounting clinical evidence acknowledges the value of the Clarity system for the effective planning and treatment of breast cancer."

Resonant Medical develops, manufactures, and markets 3D ultrasound image-guided adaptive radiotherapy products. Originally developed at McGill University Health Center, Resonant's technologies are available in more than 50 cancer centers in the United States Canada and Europe.

Related Links:
Resonant Medical
British Columbia Cancer Agency
University of British Columbia

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57 (!!!!! 1626.9683837891): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294722663 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294722663 AND published='1' LIMIT 1

58 (80.108642578125): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294722663 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294722663 AND published='1' LIMIT 1

59 (260.1146697998): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294722663 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294722663 AND published='1' LIMIT 1

60 (!!!!! 6760.835647583): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294722663 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294722663 AND published='1' LIMIT 1

61 (!!!!! 10330.200195312): select cover from jos_number where journalid in (5) and cover is not null order by left(issue,2)+right(issue,2)*12 desc limit 1

62 (!!!!! 7746.9348907471): SELECT fid FROM jos_deeppockets WHERE id=294722663 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294722663 AND published='1' LIMIT 1

63 (!!!!! 3889.0838623047): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=214 ORDER BY `ordering`

64 (169.99244689941): select jos_twitters.link from jos_twitters where cat=10

65 (179.05235290527): select jos_facebook.link from jos_facebook where cat=10

66 (234.84230041504): select jos_google_plus.link from jos_google_plus where cat=10

67 (105.85784912109): select jos_linkedin.link from jos_linkedin where cat=10

68 (84.877014160156): SELECT fid FROM jos_deeppockets WHERE id=294722663 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294722663 AND published='1' LIMIT 1

69 (61.03515625): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=214 ORDER BY `ordering`

70 (519.99092102051): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294722663 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

71 (!!!!! 1034.0213775635): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294722663 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (464.91622924805): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

73 (!!!!! 3248.929977417): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (128.03077697754): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (354.05158996582): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (96.797943115234): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (272.03559875488): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (51.975250244141): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (305.8910369873): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (47.922134399414): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (48.87580871582): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (247.00164794922): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (41.007995605469): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (35.04753112793): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (196.93374633789): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (81.062316894531): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (579.1187286377): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294722663 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

88 (46.014785766602): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294722663 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (212.9077911377): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

90 (595.8080291748): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (49.829483032227): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (217.91458129883): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (43.153762817383): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (174.99923706055): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (44.107437133789): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (264.16778564453): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (48.160552978516): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (51.021575927734): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (205.99365234375): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (46.968460083008): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (208.13941955566): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (47.922134399414): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (226.97448730469): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (263.21411132812): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294722663 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294722663 AND published='1' LIMIT 1

105 (306.12945556641): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294722663 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294722663 AND published='1' LIMIT 1

106 (107.0499420166): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294722663 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (247.00164794922): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294722663 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (837.08763122559): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294722663 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294722663 AND published='1' LIMIT 1

109 (326.87187194824): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294722663 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294722663 AND published='1' LIMIT 1

110 (212.19253540039): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294722663 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

111 (!!!!! 1631.9751739502): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294722663 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (806.80847167969): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

113 (545.02487182617): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (180.95970153809): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294722663 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294722663 AND published='1' LIMIT 1

115 (79.154968261719): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294722663 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294722663 AND published='1' LIMIT 1

116 (95.844268798828): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294722663 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294722663 AND published='1' LIMIT 1

117 (62.942504882812): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294722663 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294722663 AND published='1' LIMIT 1

118 (123.97766113281): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294722663 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294722663 AND published='1' LIMIT 1

119 (66.995620727539): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294722663 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294722663 AND published='1' LIMIT 1

120 (79.154968261719): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294722663 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294722663 AND published='1' LIMIT 1

121 (61.03515625): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294722663 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294722663 AND published='1' LIMIT 1

122 (427.0076751709): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

123 (!!!!! 28712.98789978): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

124 (584.12551879883): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294722663 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294722663 AND type='deeppockets_item' AND published='1' LIMIT 1

125 (!!!!! 9980.9169769287): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

126 (205.99365234375): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (97.990036010742): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

128 (56.982040405273): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (66.995620727539): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

130 (36.954879760742): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (395.05958557129): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

132 (61.03515625): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (60.796737670898): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

134 (41.961669921875): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (606.06002807617): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294722663 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

136 (416.99409484863): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294722663 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (214.81513977051): SELECT name FROM jos_deeppockets WHERE id=214

138 (44.822692871094): SELECT name FROM jos_deeppockets WHERE id=214

139 (700.95062255859): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))214((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

140 (637.05444335938): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))214((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (109.91096496582): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294722663 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294722663 AND published='1' LIMIT 1

142 (72.956085205078): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294722663 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294722663 AND published='1' LIMIT 1

143 (!!!!! 10497.093200684): TRUNCATE TABLE jos_trademed_module

144 (119.92454528809): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294722663 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

145 (71.048736572266): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294722663 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (692.12913513184): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294722663 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

147 (82.015991210938): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294722663 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (110.14938354492): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294722663 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294722663 AND published='1' LIMIT 1

149 (73.909759521484): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294722663 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294722663 AND published='1' LIMIT 1

150 (!!!!! 1667.0227050781): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

151 (72.002410888672): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294722663 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294722663 AND published='1' LIMIT 1

152 (55.074691772461): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294722663 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294722663 AND published='1' LIMIT 1

153 (49.114227294922): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294722663 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294722663 AND type='deeppockets_item' AND published='1' LIMIT 1

154 (105.14259338379): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=214 or channel_id is null)

155 (49.114227294922): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=214 or channel_id is null)

156 (56.028366088867): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

157 (456.80999755859): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294722663 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294722663 AND published='1' LIMIT 1

158 (102.99682617188): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294722663 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294722663 AND published='1' LIMIT 1

159 (55.074691772461): select jos_twitters.link from jos_twitters where cat=10

160 (34.809112548828): select jos_facebook.link from jos_facebook where cat=10

161 (32.901763916016): select jos_google_plus.link from jos_google_plus where cat=10

162 (36.954879760742): select jos_linkedin.link from jos_linkedin where cat=10

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