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Portable AI Technology As Accurate As Cardiologists in Detecting Rheumatic Heart Disease
By MedImaging International staff writers Posted on 24 Jan 2024
Image: The novel AI platform matches cardiologists in detecting rheumatic heart disease (Photo courtesy of Children’s National Hospital)
Rheumatic heart disease (RHD), a result of the body's response to repeated Strep A bacterial infections, can lead to permanent heart damage. Early detection is crucial, as RHD is treatable with penicillin, a commonly available antibiotic. However, millions in low-income countries lack access to specialized care, and the standard method for RHD diagnosis requires a skilled cardiologist to interpret an echocardiogram—a widely used, non-invasive ultrasound imaging technology. The absence of a cardiologist often results in undetected RHD, leading to severe cardiac complications and even death. As a result, while almost eradicated in high-income countries, while RHD has been almost entirely eradicated in high-income nations, it still impacts the lives of 40 million people in low- and middle-income countries, causing nearly 400,000 deaths annually.
In new research, scientists at Children’s National Hospital (Washington, D.C., USA) have shown that artificial intelligence (AI) can detect RHD with equivalent accuracy to a cardiologist. This breakthrough in applying advanced deep learning technology to RHD, a disease of inequity, could help prevent hundreds of thousands of deaths globally each year. The innovative AI system combines advanced ultrasound probes with portable electronic devices equipped with algorithms that diagnose RHD from echocardiograms. Distributing these devices could enable healthcare workers, even without specialized medical training, to identify RHD in regions where it is still prevalent.
The AI system was developed through extensive testing of machine learning modalities, which emulate human intelligence, and deep learning, which surpasses human learning capabilities. This dual-approach optimization led to a novel algorithm trained to interpret ultrasound images for RHD detection. The AI algorithm has already identified 39 heart characteristics associated with RHD that are imperceptible to cardiologists with the naked eye. For instance, heart size is crucial in RHD diagnosis, with current guidelines using two weight categories—above or below 66 pounds—as indirect measures. However, heart size in children within these groups can vary significantly.
The research team faced the challenge of training the AI to manage clinical variations in ultrasound images and the intricacies of analyzing color Doppler echocardiograms, typically requiring specialized human skills. In trials, the AI algorithm successfully identified mitral regurgitation, a common RHD indicator, in up to 90% of affected children. This condition leads to improper closure of mitral valve flaps, causing reverse blood flow. A pilot program in Uganda will integrate AI into the echo screening process for children at risk of RHD. The researchers believe that a handheld ultrasound probe, a tablet, and a laptop equipped with this sophisticated algorithm could significantly improve early diagnosis and alter outcomes for these children.
“This technology has the potential to extend the reach of a cardiologist to anywhere in the world,” said Kelsey Brown, M.D., a cardiology fellow at Children’s National Hospital. “In one minute, anyone trained to use our system can screen a child to find out if their heart is demonstrating signs of RHD. This will lead them to more specialized care and a simple antibiotic to prevent this degenerative disease from critically damaging their hearts.”
“One of the most effective ways to prevent rheumatic heart disease is to find the patients that are affected in the very early stages, give them monthly penicillin for pennies a day and prevent them from becoming one of the 400,000 people a year who die from this disease,” added Craig Sable, M.D., interim division chief of Cardiology at Children’s National Hospital. “Once this technology is built and distributed at a scale to address the need, we are optimistic that it holds great promise to bring highly accurate care to economically disadvantaged countries and help eradicate RHD around the world.”
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AND metakey != 'aacc'
ORDER BY `ordering`77
(60.081481933594): SELECT show_live FROM jos_com_show_setting LIMIT 178
(30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 179
(25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 180
(25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 181
(24.795532226562): SELECT show_live FROM jos_com_show_setting LIMIT 182
(25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 183
(25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 184
(25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 185
(25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 186
(26.226043701172): SELECT show_live FROM jos_com_show_setting LIMIT 187
(24.795532226562): SELECT show_live FROM jos_com_show_setting LIMIT 188
(30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 189
(25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 190
(25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 191
(41.961669921875): SELECT fid FROM jos_deeppockets
WHERE cat=10
AND id=294800001
AND (type='deeppockets_item' OR type='deeppockets_item_link')
AND published='1'
LIMIT 192
(27.894973754883): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294800001 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 193
(30.994415283203): SELECT id,name,title
FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1
AND id != 294743300
AND id != 294743301
AND id != 294743302
AND id != 294743303
AND id != 294743304
AND id != 294743305
AND id != 294743306
AND id != 294743307
AND id != 294743308
AND id != 294743309
AND id != 294743310
AND metakey != 'aacc'
ORDER BY `ordering`94
(48.160552978516): SELECT show_live FROM jos_com_show_setting LIMIT 195
(31.232833862305): SELECT show_live FROM jos_com_show_setting LIMIT 196
(29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 197
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 198
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 199
(27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1100
(41.007995605469): SELECT show_live FROM jos_com_show_setting LIMIT 1101
(27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1102
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1103
(26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1104
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1105
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1106
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1107
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1108
(63.896179199219): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800001 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800001 AND published='1'
LIMIT 1109
(41.961669921875): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800001 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800001 AND published='1'
LIMIT 1110
(53.167343139648): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.cat=10
AND dp.id=294800001
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1111
(46.968460083008): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.cat=10
AND dp.id=294800001
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1112
(94.175338745117): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800001 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800001 AND published='1'
LIMIT 1113
(79.870223999023): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800001 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800001 AND published='1'
LIMIT 1114
(62.942504882812): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.id=294800001
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1115
(541.92543029785): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.id=294800001
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1116
(553.13110351562): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp
LEFT JOIN jos_experts as ex
ON ex.id = dp.author
LEFT JOIN jos_deeppockets as dp2
ON dp2.id = dp.fid
WHERE dp.author != 0
AND dp.cat = 10
AND dp.published = 1
AND (
(dp.fid = 294743300)
OR (dp.fid = 294743301)
OR (dp.fid = 294743302)
OR (dp.fid = 294743303)
OR (dp.fid = 294743304)
OR (dp.fid = 294743305)
OR (dp.fid = 294743306)
OR (dp.fid = 294743307)
OR (dp.fid = 294743308)
OR (dp.fid = 294743309)
OR (dp.fid = 294743310)
)
ORDER BY RAND()
LIMIT 1117
(319.9577331543): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp
LEFT JOIN jos_experts as ex
ON ex.id = dp.author
LEFT JOIN jos_deeppockets as dp2
ON dp2.id = dp.fid
WHERE dp.author != 0
AND dp.cat = 10
AND dp.published = 1
AND (
(dp.fid = 294743300)
OR (dp.fid = 294743301)
OR (dp.fid = 294743302)
OR (dp.fid = 294743303)
OR (dp.fid = 294743304)
OR (dp.fid = 294743305)
OR (dp.fid = 294743306)
OR (dp.fid = 294743307)
OR (dp.fid = 294743308)
OR (dp.fid = 294743309)
OR (dp.fid = 294743310)
)
ORDER BY RAND()
LIMIT 1118
(77.962875366211): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800001 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800001 AND published='1'
LIMIT 1119
(55.074691772461): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800001 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800001 AND published='1'
LIMIT 1120
(81.062316894531): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800001 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800001 AND published='1'
LIMIT 1121
(40.054321289062): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800001 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800001 AND published='1'
LIMIT 1122
(96.08268737793): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800001 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800001 AND published='1'
LIMIT 1123
(53.882598876953): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800001 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800001 AND published='1'
LIMIT 1124
(305.8910369873): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`125
(!!!!! 17773.866653442): SELECT
*
FROM
jos_deeppockets
WHERE
jos_deeppockets.cat = 10
AND
jos_deeppockets.type = 'deeppockets_item'
AND
jos_deeppockets.published = 1
AND
jos_deeppockets.created + INTERVAL 14 DAY >= NOW()
ORDER BY
jos_deeppockets.hits DESC
LIMIT
7126
(87.02278137207): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800001 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800001 AND published='1'
LIMIT 1127
(44.107437133789): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800001 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800001 AND published='1'
LIMIT 1128
(381.9465637207): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294800001 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294800001 AND type='deeppockets_item' AND published='1' LIMIT 1129
(!!!!! 407613.03901672): (
SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.video != ''
AND
dp.video_source != ''
AND
dp.cat = 10
AND
dp.published = 1
AND
dp.type != 'deeppockets_item_link'
ORDER BY
created DESC
LIMIT
3
)
UNION
(
SELECT
dpa.id,
dpa.name,
dpa.title,
dpa.video,
dpa.video_source,
dpa.created
FROM
jos_deeppockets_archive AS dpa
WHERE
dpa.video != ''
AND
dpa.video_source != ''
AND
dpa.cat = 10
AND
dpa.published = 1
AND
dpa.type != 'deeppockets_item_link'
ORDER BY
created DESC
LIMIT
3
)
ORDER BY
created DESC
LIMIT
3130
(72.002410888672): (
SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.video != ''
AND
dp.video_source != ''
AND
dp.cat = 10
AND
dp.published = 1
AND
dp.type != 'deeppockets_item_link'
ORDER BY
created DESC
LIMIT
3
)
UNION
(
SELECT
dpa.id,
dpa.name,
dpa.title,
dpa.video,
dpa.video_source,
dpa.created
FROM
jos_deeppockets_archive AS dpa
WHERE
dpa.video != ''
AND
dpa.video_source != ''
AND
dpa.cat = 10
AND
dpa.published = 1
AND
dpa.type != 'deeppockets_item_link'
ORDER BY
created DESC
LIMIT
3
)
ORDER BY
created DESC
LIMIT
3131
(341.89224243164): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294800513
LIMIT 1132
(41.961669921875): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294800513
LIMIT 1133
(247.00164794922): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294800359
LIMIT 1134
(36.954879760742): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294800359
LIMIT 1135
(294.92378234863): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294800361
LIMIT 1136
(46.968460083008): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294800361
LIMIT 1137
(462.05520629883): SELECT *
FROM jos_deeppockets
WHERE 1=1
AND id=294800001
AND (type='deeppockets_item' OR type='deeppockets_item_link')
AND published='1'
LIMIT 1138
(315.18936157227): SELECT *
FROM jos_deeppockets_archive
WHERE 1=1
AND id=294800001
AND (type='deeppockets_item' OR type='deeppockets_item_link')
AND published='1'
LIMIT 1139
(189.06593322754): SELECT name FROM jos_deeppockets WHERE id=214140
(31.948089599609): SELECT name FROM jos_deeppockets WHERE id=214141
(422.00088500977): SELECT *,
DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up,
DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down
FROM jos_events
WHERE state=1
AND publish_up > NOW()
and extra_info REGEXP '((;)|(^))214((;)|($))' AND catid IN (0,110)
ORDER BY publish_up ASC LIMIT 3142
(335.9317779541): SELECT *,
DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up,
DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down
FROM jos_events
WHERE state=1
AND publish_up > NOW()
and extra_info REGEXP '((;)|(^))214((;)|($))' AND catid IN (0,110)
ORDER BY publish_up ASC LIMIT 3143
(61.03515625): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800001 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800001 AND published='1'
LIMIT 1144
(48.160552978516): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800001 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800001 AND published='1'
LIMIT 1145
(!!!!! 7527.1129608154): TRUNCATE TABLE jos_trademed_module146
(77.009201049805): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.cat=10
AND dp.id=294800001
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1147
(52.928924560547): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.cat=10
AND dp.id=294800001
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1148
(756.02531433105): SELECT *
FROM jos_deeppockets
WHERE 1=1
AND id=294800001
AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1149
(50.067901611328): SELECT *
FROM jos_deeppockets
WHERE 1=1
AND id=294800001
AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1150
(52.928924560547): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800001 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800001 AND published='1'
LIMIT 1151
(39.100646972656): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800001 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800001 AND published='1'
LIMIT 1152
(996.11282348633): SELECT jos_item.*
FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id
WHERE 1=1
AND (jos_item.imgMini<>'')
AND jos_item.type='L'
AND jos_item.numberID= (
SELECT jos_number.id
FROM jos_number
WHERE jos_number.journalID IN (10)
and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P')
ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC
LIMIT 0,1
)
ORDER BY RAND() DESC LIMIT 6153
(50.783157348633): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800001 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800001 AND published='1'
LIMIT 1154
(41.961669921875): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800001 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800001 AND published='1'
LIMIT 1155
(36.954879760742): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294800001 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294800001 AND type='deeppockets_item' AND published='1' LIMIT 1156
(459.90943908691): select distinct links.*
from jos_textlinks links
join jos_textlinks_placement placement on links.id=placement.link_id
where journal_id=(10) and (channel_id=214 or channel_id is null)157
(39.100646972656): select distinct links.*
from jos_textlinks links
join jos_textlinks_placement placement on links.id=placement.link_id
where journal_id=(10) and (channel_id=214 or channel_id is null)158
(32.186508178711): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1159
(101.08947753906): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800001 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800001 AND published='1'
LIMIT 1160
(46.014785766602): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800001 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800001 AND published='1'
LIMIT 1161
(235.08071899414): select jos_twitters.link from jos_twitters where cat=10162
(30.994415283203): select jos_facebook.link from jos_facebook where cat=10163
(29.087066650391): select jos_google_plus.link from jos_google_plus where cat=10164
(26.941299438477): select jos_linkedin.link from jos_linkedin where cat=10165
(247.95532226562): update jos_bannersmanager_banner
set impmade=impmade+1
where id in(14615,14202,14203)166
(!!!!! 1133.918762207): insert into jos_banners_delta values (14615,'2025-05-09 12:35:46','3.144.39.8','view'),(14202,'2025-05-09 12:35:46','3.144.39.8','view'),(14203,'2025-05-09 12:35:46','3.144.39.8','view')
Expo
.jpg "Image: CT coronary angiography for diagnosing coronary artery disease offers advantages over other diagnostic tests (Photo courtesy of 123RF)")
.jpg "Image: Exemplary illustration of the labeling and segmentation process (Photo courtesy of TUM)")
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