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Real-Time 3D Imaging Provides First-of-Its-Kind View of X-Rays Hitting Inside Body During Radiation Therapy

By MedImaging International staff writers
Posted on 05 Jan 2023

Image: Tracking radiation treatment in real time promises safer, more effective cancer therapy (Photo courtesy of Pexels)

Radiation is used in treatment for hundreds of thousands of cancer patients each year, bombarding an area of the body with high energy waves and particles, usually X-rays. The radiation can kill cancer cells outright or damage them so that they can’t spread. These benefits are undermined by a lack of precision, as radiation treatment often kills and damages healthy cells in the areas surrounding a tumor. It can also raise the risk of developing new cancers. Now, radiation, used to treat half of all cancer patients, can be measured during treatment for the first time with precise 3D imaging. By capturing and amplifying tiny sound waves created when X-rays heat tissues in the body, medical professionals can map the radiation dose within the body, giving them new data to guide treatments in real time. It’s a first-of-its-kind view of an interaction doctors have previously been unable to “see.”

With real-time 3D imaging developed at the University of Michigan (Ann Arbor, MI, USA), doctors can more accurately direct the radiation toward cancerous cells and limit the exposure of adjacent tissues. To do that, they simply need to “listen.” When X-rays are absorbed by tissues in the body, they are turned into thermal energy. That heating causes the tissue to expand rapidly, and that expansion creates a sound wave. The acoustic wave is weak and usually undetectable by typical ultrasound technology. U-M’s new ionizing radiation acoustic imaging system detects the wave with an array of ultrasonic transducers positioned on the patient’s side. The signal is amplified and then transferred into an ultrasound device for image reconstruction. With the images in-hand, an oncology clinic can alter the level or trajectory of radiation during the process to ensure safer and more effective treatments. Another benefit of the technology is it can be easily added to current radiation therapy equipment without drastically changing the processes that clinicians are used to.

“In the future, we could use the imaging information to compensate for uncertainties that arise from positioning, organ motion and anatomical variation during radiation therapy,” said Wei Zhang, a research investigator in biomedical engineering and the study’s first author. “That would allow us to deliver the dose to the cancer tumor with pinpoint accuracy.”

“In future applications, this technology can be used to personalize and adapt each radiation treatment to assure normal tissues are kept to a safe dose and that the tumor receives the dose intended,” said Kyle Cuneo, associate professor of radiation oncology at Michigan Medicine. “This technology would be especially beneficial in situations where the target is adjacent to radiation sensitive organs such as the small bowel or stomach.”

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63 (!!!!! 1165.1515960693): SELECT fid FROM jos_deeppockets WHERE id=294795877 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294795877 AND published='1' LIMIT 1

64 (!!!!! 2378.9405822754): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=213 ORDER BY `ordering`

65 (!!!!! 1560.9264373779): select jos_twitters.link from jos_twitters where cat=10

66 (!!!!! 1119.1368103027): select jos_facebook.link from jos_facebook where cat=10

67 (730.03768920898): select jos_google_plus.link from jos_google_plus where cat=10

68 (!!!!! 4027.1282196045): select jos_linkedin.link from jos_linkedin where cat=10

69 (!!!!! 10900.974273682): SELECT fid FROM jos_deeppockets WHERE id=294795877 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294795877 AND published='1' LIMIT 1

70 (!!!!! 5691.0514831543): SELECT id,name,sponsor_text FROM jos_deeppockets dp left outer join jos_channel_sponsor cs on dp.id=cs.fid WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id=213 ORDER BY `ordering`

71 (!!!!! 2567.0528411865): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294795877 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

72 (998.97384643555): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294795877 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

73 (83.92333984375): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

74 (!!!!! 3104.2098999023): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (71.048736572266): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (660.89630126953): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (58.889389038086): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (52.928924560547): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (71.048736572266): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (47.922134399414): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (49.114227294922): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (214.0998840332): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (36.954879760742): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (705.00373840332): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (56.982040405273): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (53.167343139648): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (38.862228393555): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (!!!!! 1071.9299316406): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294795877 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

89 (56.028366088867): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294795877 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

90 (45.061111450195): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

91 (!!!!! 7608.8905334473): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (!!!!! 7961.0347747803): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (!!!!! 7833.0039978027): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (!!!!! 7986.7839813232): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (!!!!! 7864.9520874023): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (!!!!! 7954.8358917236): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (!!!!! 7808.9237213135): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (!!!!! 8005.1422119141): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (!!!!! 7819.1757202148): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (!!!!! 7993.221282959): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (!!!!! 7982.0156097412): SELECT show_live FROM jos_com_show_setting LIMIT 1

102 (!!!!! 7816.0762786865): SELECT show_live FROM jos_com_show_setting LIMIT 1

103 (!!!!! 7834.1960906982): SELECT show_live FROM jos_com_show_setting LIMIT 1

104 (!!!!! 7928.1330108643): SELECT show_live FROM jos_com_show_setting LIMIT 1

105 (!!!!! 7462.9783630371): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294795877 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294795877 AND published='1' LIMIT 1

106 (!!!!! 7998.9433288574): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294795877 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294795877 AND published='1' LIMIT 1

107 (!!!!! 7915.0199890137): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294795877 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (!!!!! 4519.9394226074): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294795877 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

109 (!!!!! 2159.1186523438): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294795877 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294795877 AND published='1' LIMIT 1

110 (!!!!! 12796.16355896): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294795877 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294795877 AND published='1' LIMIT 1

111 (!!!!! 7329.9407958984): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294795877 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

112 (!!!!! 8713.0069732666): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294795877 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

113 (!!!!! 1043.0812835693): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

114 (611.0668182373): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

115 (!!!!! 1045.9423065186): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294795877 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294795877 AND published='1' LIMIT 1

116 (797.98698425293): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294795877 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294795877 AND published='1' LIMIT 1

117 (!!!!! 6127.1190643311): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294795877 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294795877 AND published='1' LIMIT 1

118 (!!!!! 5508.8996887207): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294795877 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294795877 AND published='1' LIMIT 1

119 (!!!!! 2147.912979126): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294795877 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294795877 AND published='1' LIMIT 1

120 (281.81076049805): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294795877 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294795877 AND published='1' LIMIT 1

121 (!!!!! 1619.1005706787): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294795877 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294795877 AND published='1' LIMIT 1

122 (!!!!! 3881.9313049316): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294795877 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294795877 AND published='1' LIMIT 1

123 (794.88754272461): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

124 (!!!!! 76806.06842041): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

125 (!!!!! 1929.0447235107): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294795877 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294795877 AND type='deeppockets_item' AND published='1' LIMIT 1

126 (!!!!! 25022.983551025): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

127 (77.962875366211): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

128 (661.13471984863): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

129 (633.00132751465): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803337 LIMIT 1

130 (63.896179199219): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

131 (469.92301940918): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294803276 LIMIT 1

132 (650.16746520996): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

133 (225.06713867188): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets_archive AS dp WHERE dp.id = 294803276 LIMIT 1

134 (425.10032653809): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

135 (50.067901611328): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294802958 LIMIT 1

136 (874.04251098633): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294795877 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

137 (!!!!! 2938.985824585): SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294795877 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

138 (!!!!! 1116.9910430908): SELECT name FROM jos_deeppockets WHERE id=213

139 (261.06834411621): SELECT name FROM jos_deeppockets WHERE id=213

140 (807.04689025879): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))213((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

141 (!!!!! 1430.9883117676): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))213((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

142 (!!!!! 2805.9482574463): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294795877 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294795877 AND published='1' LIMIT 1

143 (745.05805969238): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294795877 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294795877 AND published='1' LIMIT 1

144 (!!!!! 17565.965652466): TRUNCATE TABLE jos_trademed_module

145 (!!!!! 6496.1910247803): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294795877 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

146 (!!!!! 3736.9728088379): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294795877 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

147 (!!!!! 3001.9283294678): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294795877 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

148 (!!!!! 7733.8218688965): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294795877 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

149 (!!!!! 7688.045501709): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294795877 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294795877 AND published='1' LIMIT 1

150 (!!!!! 5803.108215332): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294795877 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294795877 AND published='1' LIMIT 1

151 (!!!!! 3359.0793609619): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

152 (!!!!! 2854.8240661621): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294795877 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294795877 AND published='1' LIMIT 1

153 (83.92333984375): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294795877 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294795877 AND published='1' LIMIT 1

154 (55.074691772461): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294795877 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294795877 AND type='deeppockets_item' AND published='1' LIMIT 1

155 (222.20611572266): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=213 or channel_id is null)

156 (41.961669921875): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=213 or channel_id is null)

157 (301.83792114258): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

158 (478.02925109863): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294795877 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294795877 AND published='1' LIMIT 1

159 (80.108642578125): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294795877 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294795877 AND published='1' LIMIT 1

160 (!!!!! 7512.092590332): select jos_twitters.link from jos_twitters where cat=10

161 (530.00450134277): select jos_facebook.link from jos_facebook where cat=10

162 (815.15312194824): select jos_google_plus.link from jos_google_plus where cat=10

163 (776.05247497559): select jos_linkedin.link from jos_linkedin where cat=10

164 (!!!!! 7621.0498809814): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

165 (!!!!! 12001.037597656): insert into jos_banners_delta values (14615,'2025-08-03 20:18:10','216.73.216.210','view'),(14202,'2025-08-03 20:18:10','216.73.216.210','view'),(14203,'2025-08-03 20:18:10','216.73.216.210','view')

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