We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.
By MedImaging International staff writers Posted on 20 Aug 2019
Image: Focusing an electron beam can spare tissues surrounding a tumor, according to a new study (Photo courtesy of the University of Strathclyde).
A new study shows that very high-energy electron (VHEE) beams could potentially enable clinicians to accurately target malignancies and reduce damage to surrounding tissues.
Researchers at the University of Strathclyde (United Kingdom), the National Physical Laboratory (NPL; Teddington, United Kingdom), and other institutions conducted a water phantom study (based on Monte Carlo simulations) of a magnetic “lens” that can focus particle beams within the body. Concentrating such a VHEE beam into a small, well-defined volumetric element, which can be shaped or scanned to treat deep-seated tumors, allows the dose to surrounding tissue to be distributed over a larger volume.
The result is reduced peak surface and exit doses by more than one order of magnitude, compared with a collimated beam. The magnetic lens, which is in effect an ultra-compact laser-wakefield accelerator, is only millimeters long, and can be easily focused. The researchers are now planning to expand the study and are setting up a medical beamline with high energy electron accelerators at the Scottish Centre for the Application of Plasma-based Accelerator (SCAPA; Strathclyde, United Kingdom). The study was published on July 25, 2019, in Nature Scientific Reports.
“Electrons, much like protons, have properties specific to particles. The significantly smaller electron mass, however, must be compensated for by increasing their energy, and therefore inertia, to achieve an effect similar to high mass particles,” said lead author Strathclyde PhD student Karolina Kokurewicz, MSc. “We push the envelope, showing that a VHEE beam, when focused, can be easily controlled to target precisely tumors similar to beam scanning modalities. The net effect is a greatly enhanced dose profile that conforms closely to the target volumes and potentially provides better tumor control.”
“One of the challenges in radiotherapy is to deposit a high radiation dose in a way that the dose fully ‘conforms’ to the tumor, to ensure that all cancerous cells are killed, while preventing damage to healthy cells,” said senior author Professor Dino Jaroszynski, PhD, of the University of Strathclyde department of physics. “In a similar way to a magnifying glass focusing the sun's rays to a small spot, we propose to focus a particle beam to a small spot using a magnetic lens to ablate the tumor.”
Common forms of radiation currently used in RT include bremsstrahlung X-rays produced by linear accelerators. These relatively low energy electron beams can be used directly to irradiate tumors, but they do not penetrate deeply into the body. To irradiate the tumor with sufficient radiation to kill all tumor cells, the X-ray beam is often rotated, while the patient remains stationary, thus superimposing multiple beams with different energies to produce a spread-out-Bragg peak region. This, however, results in an increased entrance dose, which could be avoided by focusing VHEE beams.
1
(125.88500976562): SET sql_mode = 'MYSQL40'2
(87.976455688477): SELECT folder, element, published, params
FROM jos_mambots
WHERE published >= 1
AND access <= 0
AND folder = 'system'
ORDER BY ordering3
(739.09759521484): SELECT template
FROM jos_templates_menu
WHERE client_id = 0
AND ( menuid = 0 OR menuid = 294779048 )
ORDER BY menuid DESC
LIMIT 14
(339.98489379883): DELETE FROM jos_session
WHERE
time < 1758570902
AND guest = 1
AND userid = 05
(70.095062255859): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 16
(52.928924560547): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 17
(46.968460083008): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 18
(476.12190246582): SELECT *
FROM jos_menu
WHERE id = 2947790489
(858.06846618652): SELECT dp.*,
ch.title as channel,
ch.name as channel_name,
exp.name as author_name,
exp.specialization as author_specialization, exp.images as author_photo
FROM jos_deeppockets as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
#AND dp.cat=10
AND dp.id=294779048
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 110
(879.04930114746): SELECT dp.*,
ch.title as channel,
ch.name as channel_name,
exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo
FROM jos_deeppockets_archive as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
#AND dp.cat=10
AND dp.id=294779048
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 111
(116.82510375977): SELECT dp.*,
ch.title as channel,
ch.name as channel_name,
exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo
FROM jos_deeppockets_archive as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
#AND dp.cat=10
AND dp.id=294779048
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 112
(!!!!! 1460.075378418): SELECT *
FROM jos_deeppockets
WHERE 1=1
AND cat=10
AND type='deeppockets_item'
AND published='1'
AND (id<>294779048)
AND (fid=213)
ORDER BY id DESC, `created` DESC
LIMIT 0,1613
(207.18574523926): SELECT *
FROM jos_deeppockets
WHERE 1=1
AND cat=10
AND type='deeppockets_item'
AND published='1'
AND (id<>294779048)
AND (fid=213)
ORDER BY id DESC, `created` DESC
LIMIT 0,1614
(!!!!! 15204.906463623): SELECT jos_item.*
FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id
WHERE 1=1
AND (jos_item.imgMini<>'')
AND jos_item.type='P'
AND jos_item.numberID= (
SELECT jos_number.id
FROM jos_number
WHERE jos_number.journalID IN (10)
and jos_item.fid=213
and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P')
ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC
LIMIT 0,1
)
AND (jos_number.channelID=294779048 OR jos_number.channelID=0)
ORDER BY RAND() DESC LIMIT 315
(!!!!! 5842.924118042): SELECT jos_item.*
FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id
WHERE 1=1
AND (jos_item.imgMini<>'')
AND jos_item.type='P'
AND jos_item.numberID= (
SELECT jos_number.id
FROM jos_number
WHERE jos_number.journalID IN (10)
and jos_item.fid=213
and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P')
ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC
LIMIT 0,1
)
AND (jos_number.channelID=294779048 OR jos_number.channelID=0)
ORDER BY RAND() DESC LIMIT 316
(!!!!! 8713.960647583): SELECT jos_item.*
FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id
WHERE 1=1
AND (jos_item.imgMini<>'')
AND jos_item.type='P'
AND jos_item.numberID= (
SELECT jos_number.id
FROM jos_number
WHERE jos_number.journalID IN (10)
and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P')
ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC
LIMIT 0,1
)
AND (jos_number.channelID=294779048 OR jos_number.channelID=0)
ORDER BY RAND() DESC LIMIT 317
(!!!!! 10569.81086731): SELECT jos_item.*
FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id
WHERE 1=1
AND (jos_item.imgMini<>'')
AND jos_item.type='P'
AND jos_item.numberID= (
SELECT jos_number.id
FROM jos_number
WHERE jos_number.journalID IN (10)
and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P')
ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC
LIMIT 0,1
)
AND (jos_number.channelID=294779048 OR jos_number.channelID=0)
ORDER BY RAND() DESC LIMIT 318
(!!!!! 11448.14491272): SELECT name,id,title FROM jos_deeppockets WHERE id=213 LIMIT 119
(82.015991210938): SELECT name,id,title FROM jos_deeppockets WHERE id=213 LIMIT 120
(!!!!! 1119.1368103027): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.id=294779048
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 121
(626.0871887207): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.id=294779048
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 122
(128.03077697754): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.id=294779048
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 123
(81.777572631836): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.id=294779048
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 124
(895.02334594727): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.cat=10
AND dp.id=294779048
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 125
(823.02093505859): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.cat=10
AND dp.id=294779048
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 126
(178.09867858887): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.id=294779048
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 127
(102.99682617188): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.id=294779048
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 128
(190.01960754395): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.cat=10
AND dp.id=294779048
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 129
(92.029571533203): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.cat=10
AND dp.id=294779048
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 130
(113.01040649414): SELECT
conference_items.channel_id,
conference_items.tracking_code
FROM
conference_items
LEFT JOIN
conference_groups ON conference_groups.id = conference_items.group_id
LEFT JOIN
jos_deeppockets ON jos_deeppockets.id = conference_items.channel_id
LEFT JOIN
jos_journal ON jos_journal.cat = jos_deeppockets.cat AND jos_journal.real = 1 AND jos_journal.directory IS NOT NULL
WHERE
1 = 1
ORDER BY
conference_items.id31
(638.00811767578): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294779048
LIMIT 132
(61.03515625): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294779048
LIMIT 133
(370.97930908203): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets_archive AS dp
WHERE
dp.id = 294779048
LIMIT 134
(60.081481933594): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets_archive AS dp
WHERE
dp.id = 294779048
LIMIT 135
(!!!!! 1327.9914855957): SELECT id, title, module, position, content, showtitle, params
FROM jos_modules AS m
INNER JOIN jos_modules_menu AS mm ON mm.moduleid = m.id
WHERE m.published = 1
AND m.access <= 0
AND m.client_id != 1
AND ( mm.menuid = 0 OR mm.menuid = 294779048 )
ORDER BY ordering36
(!!!!! 1528.9783477783): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 137
(84.877014160156): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 138
(!!!!! 7509.9468231201): SELECT
*
FROM
jos_bannersmanager_banner
WHERE
`groupid` = 98
AND
`site_id` = 10
AND
`published` = 139
(!!!!! 13962.984085083): SELECT
*
FROM
jos_bannersmanager_banner
WHERE
`groupid` = 99
AND
`site_id` = 10
AND
`published` = 140
(221.01402282715): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 141
(107.0499420166): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 142
(283.95652770996): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294779048
LIMIT 143
(79.870223999023): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294779048
LIMIT 144
(61.03515625): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets_archive AS dp
WHERE
dp.id = 294779048
LIMIT 145
(52.928924560547): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets_archive AS dp
WHERE
dp.id = 294779048
LIMIT 146
(199.79476928711): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 147
(125.16975402832): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 148
(221.96769714355): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 149
(90.122222900391): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 150
(221.01402282715): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 151
(93.221664428711): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 152
(509.97734069824): SELECT name FROM jos_deeppockets WHERE id=294779048 LIMIT 153
(383.13865661621): SELECT name FROM jos_deeppockets_archive WHERE id=294779048 LIMIT 154
(82.015991210938): SELECT a.*
FROM jos_components AS a
WHERE ( a.admin_menu_link = 'option=com_syndicate' OR a.admin_menu_link = 'option=com_syndicate&hidemainmenu=1' )
AND a.option = 'com_syndicate'55
(602.00691223145): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.cat=10
AND dp.id=294779048
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 156
(!!!!! 1046.895980835): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.cat=10
AND dp.id=294779048
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 157
(!!!!! 7189.0354156494): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 158
(683.06922912598): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 159
(!!!!! 3123.9986419678): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 160
(217.91458129883): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 161
(!!!!! 3031.9690704346): select cover from jos_number
where journalid in (5) and cover is not null
order by left(issue,2)+right(issue,2)*12 desc limit 162
(!!!!! 1246.9291687012): SELECT fid FROM jos_deeppockets WHERE id=294779048 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294779048 AND published='1' LIMIT 163
(!!!!! 2353.9066314697): SELECT id,name,sponsor_text
FROM jos_deeppockets dp
left outer join jos_channel_sponsor cs
on dp.id=cs.fid
WHERE cat=10
AND TYPE='file_folder'
AND published=1
AND id=213
ORDER BY `ordering`64
(!!!!! 3465.1756286621): select jos_twitters.link from jos_twitters where cat=1065
(633.00132751465): select jos_facebook.link from jos_facebook where cat=1066
(65.088272094727): select jos_google_plus.link from jos_google_plus where cat=1067
(51.021575927734): select jos_linkedin.link from jos_linkedin where cat=1068
(133.03756713867): SELECT fid FROM jos_deeppockets WHERE id=294779048 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294779048 AND published='1' LIMIT 169
(339.03121948242): SELECT id,name,sponsor_text
FROM jos_deeppockets dp
left outer join jos_channel_sponsor cs
on dp.id=cs.fid
WHERE cat=10
AND TYPE='file_folder'
AND published=1
AND id=213
ORDER BY `ordering`70
(!!!!! 1527.0709991455): SELECT fid FROM jos_deeppockets
WHERE cat=10
AND id=294779048
AND (type='deeppockets_item' OR type='deeppockets_item_link')
AND published='1'
LIMIT 171
(344.99168395996): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294779048 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 172
(117.06352233887): SELECT id,name,title
FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1
AND id != 294743300
AND id != 294743301
AND id != 294743302
AND id != 294743303
AND id != 294743304
AND id != 294743305
AND id != 294743306
AND id != 294743307
AND id != 294743308
AND id != 294743309
AND id != 294743310
AND metakey != 'aacc'
ORDER BY `ordering`73
(88.930130004883): SELECT show_live FROM jos_com_show_setting LIMIT 174
(45.061111450195): SELECT show_live FROM jos_com_show_setting LIMIT 175
(44.822692871094): SELECT show_live FROM jos_com_show_setting LIMIT 176
(34.809112548828): SELECT show_live FROM jos_com_show_setting LIMIT 177
(186.92016601562): SELECT show_live FROM jos_com_show_setting LIMIT 178
(43.153762817383): SELECT show_live FROM jos_com_show_setting LIMIT 179
(44.107437133789): SELECT show_live FROM jos_com_show_setting LIMIT 180
(38.862228393555): SELECT show_live FROM jos_com_show_setting LIMIT 181
(!!!!! 1901.1497497559): SELECT show_live FROM jos_com_show_setting LIMIT 182
(90.837478637695): SELECT show_live FROM jos_com_show_setting LIMIT 183
(146.15058898926): SELECT show_live FROM jos_com_show_setting LIMIT 184
(55.074691772461): SELECT show_live FROM jos_com_show_setting LIMIT 185
(43.153762817383): SELECT show_live FROM jos_com_show_setting LIMIT 186
(116.82510375977): SELECT show_live FROM jos_com_show_setting LIMIT 187
(78.916549682617): SELECT fid FROM jos_deeppockets
WHERE cat=10
AND id=294779048
AND (type='deeppockets_item' OR type='deeppockets_item_link')
AND published='1'
LIMIT 188
(87.02278137207): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294779048 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 189
(161.88621520996): SELECT id,name,title
FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1
AND id != 294743300
AND id != 294743301
AND id != 294743302
AND id != 294743303
AND id != 294743304
AND id != 294743305
AND id != 294743306
AND id != 294743307
AND id != 294743308
AND id != 294743309
AND id != 294743310
AND metakey != 'aacc'
ORDER BY `ordering`90
(217.91458129883): SELECT show_live FROM jos_com_show_setting LIMIT 191
(!!!!! 4364.013671875): SELECT show_live FROM jos_com_show_setting LIMIT 192
(996.11282348633): SELECT show_live FROM jos_com_show_setting LIMIT 193
(82.969665527344): SELECT show_live FROM jos_com_show_setting LIMIT 194
(40.054321289062): SELECT show_live FROM jos_com_show_setting LIMIT 195
(36.001205444336): SELECT show_live FROM jos_com_show_setting LIMIT 196
(259.1609954834): SELECT show_live FROM jos_com_show_setting LIMIT 197
(!!!!! 1368.9994812012): SELECT show_live FROM jos_com_show_setting LIMIT 198
(!!!!! 2382.0400238037): SELECT show_live FROM jos_com_show_setting LIMIT 199
(86.069107055664): SELECT show_live FROM jos_com_show_setting LIMIT 1100
(!!!!! 1228.0941009521): SELECT show_live FROM jos_com_show_setting LIMIT 1101
(68.187713623047): SELECT show_live FROM jos_com_show_setting LIMIT 1102
(120.16296386719): SELECT show_live FROM jos_com_show_setting LIMIT 1103
(777.00614929199): SELECT show_live FROM jos_com_show_setting LIMIT 1104
(592.94700622559): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 1105
(252.00843811035): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 1106
(200.03318786621): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.cat=10
AND dp.id=294779048
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1107
(102.04315185547): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.cat=10
AND dp.id=294779048
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1108
(909.09004211426): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 1109
(118.97087097168): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 1110
(84.161758422852): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.id=294779048
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1111
(686.1686706543): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.id=294779048
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1112
(656.1279296875): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp
LEFT JOIN jos_experts as ex
ON ex.id = dp.author
LEFT JOIN jos_deeppockets as dp2
ON dp2.id = dp.fid
WHERE dp.author != 0
AND dp.cat = 10
AND dp.published = 1
AND (
(dp.fid = 294743300)
OR (dp.fid = 294743301)
OR (dp.fid = 294743302)
OR (dp.fid = 294743303)
OR (dp.fid = 294743304)
OR (dp.fid = 294743305)
OR (dp.fid = 294743306)
OR (dp.fid = 294743307)
OR (dp.fid = 294743308)
OR (dp.fid = 294743309)
OR (dp.fid = 294743310)
)
ORDER BY RAND()
LIMIT 1113
(407.93418884277): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp
LEFT JOIN jos_experts as ex
ON ex.id = dp.author
LEFT JOIN jos_deeppockets as dp2
ON dp2.id = dp.fid
WHERE dp.author != 0
AND dp.cat = 10
AND dp.published = 1
AND (
(dp.fid = 294743300)
OR (dp.fid = 294743301)
OR (dp.fid = 294743302)
OR (dp.fid = 294743303)
OR (dp.fid = 294743304)
OR (dp.fid = 294743305)
OR (dp.fid = 294743306)
OR (dp.fid = 294743307)
OR (dp.fid = 294743308)
OR (dp.fid = 294743309)
OR (dp.fid = 294743310)
)
ORDER BY RAND()
LIMIT 1114
(121.11663818359): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 1115
(87.976455688477): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 1116
(101.08947753906): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 1117
(61.988830566406): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 1118
(109.91096496582): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 1119
(58.889389038086): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 1120
(76.055526733398): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 1121
(58.889389038086): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 1122
(325.91819763184): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`123
(!!!!! 86838.006973267): SELECT
*
FROM
jos_deeppockets
WHERE
jos_deeppockets.cat = 10
AND
jos_deeppockets.type = 'deeppockets_item'
AND
jos_deeppockets.published = 1
AND
jos_deeppockets.created + INTERVAL 14 DAY >= NOW()
ORDER BY
jos_deeppockets.hits DESC
LIMIT
7124
(869.0357208252): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294779048 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294779048 AND type='deeppockets_item' AND published='1' LIMIT 1125
(!!!!! 42165.994644165): (
SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.video != ''
AND
dp.video_source != ''
AND
dp.cat = 10
AND
dp.published = 1
AND
dp.type != 'deeppockets_item_link'
ORDER BY
created DESC
LIMIT
3
)
UNION
(
SELECT
dpa.id,
dpa.name,
dpa.title,
dpa.video,
dpa.video_source,
dpa.created
FROM
jos_deeppockets_archive AS dpa
WHERE
dpa.video != ''
AND
dpa.video_source != ''
AND
dpa.cat = 10
AND
dpa.published = 1
AND
dpa.type != 'deeppockets_item_link'
ORDER BY
created DESC
LIMIT
3
)
ORDER BY
created DESC
LIMIT
3126
(91.075897216797): (
SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.video != ''
AND
dp.video_source != ''
AND
dp.cat = 10
AND
dp.published = 1
AND
dp.type != 'deeppockets_item_link'
ORDER BY
created DESC
LIMIT
3
)
UNION
(
SELECT
dpa.id,
dpa.name,
dpa.title,
dpa.video,
dpa.video_source,
dpa.created
FROM
jos_deeppockets_archive AS dpa
WHERE
dpa.video != ''
AND
dpa.video_source != ''
AND
dpa.cat = 10
AND
dpa.published = 1
AND
dpa.type != 'deeppockets_item_link'
ORDER BY
created DESC
LIMIT
3
)
ORDER BY
created DESC
LIMIT
3127
(46.014785766602): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294803337
LIMIT 1128
(35.04753112793): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294803337
LIMIT 1129
(43.153762817383): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294803276
LIMIT 1130
(33.855438232422): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294803276
LIMIT 1131
(549.0779876709): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets_archive AS dp
WHERE
dp.id = 294803276
LIMIT 1132
(!!!!! 4799.1275787354): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets_archive AS dp
WHERE
dp.id = 294803276
LIMIT 1133
(!!!!! 9531.9747924805): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294802958
LIMIT 1134
(79.870223999023): SELECT
dp.id,
dp.name,
dp.title,
dp.video,
dp.video_source,
dp.created
FROM
jos_deeppockets AS dp
WHERE
dp.id = 294802958
LIMIT 1135
(574.82719421387): SELECT *
FROM jos_deeppockets
WHERE 1=1
AND id=294779048
AND (type='deeppockets_item' OR type='deeppockets_item_link')
AND published='1'
LIMIT 1136
(!!!!! 1580.9535980225): SELECT *
FROM jos_deeppockets_archive
WHERE 1=1
AND id=294779048
AND (type='deeppockets_item' OR type='deeppockets_item_link')
AND published='1'
LIMIT 1137
(313.99726867676): SELECT name FROM jos_deeppockets WHERE id=213138
(49.829483032227): SELECT name FROM jos_deeppockets WHERE id=213139
(839.9486541748): SELECT *,
DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up,
DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down
FROM jos_events
WHERE state=1
AND publish_up > NOW()
and extra_info REGEXP '((;)|(^))213((;)|($))' AND catid IN (0,110)
ORDER BY publish_up ASC LIMIT 3140
(782.01293945312): SELECT *,
DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up,
DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down
FROM jos_events
WHERE state=1
AND publish_up > NOW()
and extra_info REGEXP '((;)|(^))213((;)|($))' AND catid IN (0,110)
ORDER BY publish_up ASC LIMIT 3141
(176.90658569336): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 1142
(92.983245849609): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 1143
(!!!!! 32073.020935059): TRUNCATE TABLE jos_trademed_module144
(337.12387084961): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.cat=10
AND dp.id=294779048
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1145
(107.0499420166): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
LEFT JOIN jos_experts as exp
ON exp.id = dp.author
LEFT JOIN jos_deeppockets as ch
ON dp.fid = ch.id
WHERE 1=1
AND dp.cat=10
AND dp.id=294779048
AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
AND dp.published='1' LIMIT 1146
(922.91831970215): SELECT *
FROM jos_deeppockets
WHERE 1=1
AND id=294779048
AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1147
(176.19132995605): SELECT *
FROM jos_deeppockets
WHERE 1=1
AND id=294779048
AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1148
(114.20249938965): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 1149
(79.154968261719): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 1150
(!!!!! 1673.9368438721): SELECT jos_item.*
FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id
WHERE 1=1
AND (jos_item.imgMini<>'')
AND jos_item.type='L'
AND jos_item.numberID= (
SELECT jos_number.id
FROM jos_number
WHERE jos_number.journalID IN (10)
and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P')
ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC
LIMIT 0,1
)
ORDER BY RAND() DESC LIMIT 6151
(!!!!! 2279.0431976318): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 1152
(!!!!! 4352.8079986572): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 1153
(!!!!! 2859.8308563232): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294779048 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294779048 AND type='deeppockets_item' AND published='1' LIMIT 1154
(!!!!! 5025.8636474609): select distinct links.*
from jos_textlinks links
join jos_textlinks_placement placement on links.id=placement.link_id
where journal_id=(10) and (channel_id=213 or channel_id is null)155
(!!!!! 20599.842071533): select distinct links.*
from jos_textlinks links
join jos_textlinks_placement placement on links.id=placement.link_id
where journal_id=(10) and (channel_id=213 or channel_id is null)156
(!!!!! 3770.112991333): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1157
(!!!!! 3480.9112548828): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 1158
(!!!!! 3935.0986480713): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294779048 AND published='1'
union
SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294779048 AND published='1'
LIMIT 1159
(!!!!! 1358.9859008789): select jos_twitters.link from jos_twitters where cat=10160
(87.976455688477): select jos_facebook.link from jos_facebook where cat=10161
(55.074691772461): select jos_google_plus.link from jos_google_plus where cat=10162
(47.922134399414): select jos_linkedin.link from jos_linkedin where cat=10163
(417.94776916504): update jos_bannersmanager_banner
set impmade=impmade+1
where id in(14615,14202,14203)164
(!!!!! 2470.9701538086): insert into jos_banners_delta values (14615,'2025-09-22 20:10:04','216.73.216.167','view'),(14202,'2025-09-22 20:10:04','216.73.216.167','view'),(14203,'2025-09-22 20:10:04','216.73.216.167','view')
Expo
.jpeg "Image: The AI-powered lung ultrasound tool outperformed human experts by 9% in diagnosing TB (Photo courtesy of Adobe Stock)")
Client Login